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- References [13]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 10305-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- PLK1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PLK1 antibody (Cat. #10305-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Oxcarbazepine induces mitotic catastrophe and apoptosis in NRK-52E proximal tubular cells.
Vangl2 participates in the primary ciliary assembly under low fluid shear stress in hUVECs.
Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer.
Stimuli-Responsive and Highly Penetrable Nanoparticles as a Multifunctional Nanoplatform for Boosting Nonsmall Cell Lung Cancer siRNA Therapy.
CDK1-PLK1/SGOL2/ANLN pathway mediating abnormal cell division in cell cycle may be a critical process in hepatocellular carcinoma.
PLK1 Inhibition alleviates transplant-associated obliterative bronchiolitis by suppressing myofibroblast differentiation.
PHF7 is a novel histone H2A E3 ligase prior to histone-to-protamine exchange during spermiogenesis.
Translation control of the immune checkpoint in cancer and its therapeutic targeting.
pH-responsive hybrid nanoparticle with enhanced dissociation characteristic for siRNA delivery.
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
Impact of iASPP on chemoresistance through PLK1 and autophagy in ovarian clear cell carcinoma.
Effects of PLK1 on proliferation, invasion and metastasis of gastric cancer cells through epithelial-mesenchymal transition.
53BP1 and BRCA1 control pathway choice for stalled replication restart.
Ota M, Funakoshi T, Aki T, Unuma K, Uemura K
Toxicology letters 2021 Oct 10;350:240-248
Toxicology letters 2021 Oct 10;350:240-248
Vangl2 participates in the primary ciliary assembly under low fluid shear stress in hUVECs.
Sheng X, Gao S, Sheng Y, Xie X, Wang J, He Y
Cell and tissue research 2021 Nov 5;
Cell and tissue research 2021 Nov 5;
Hyperactivation of HER2-SHCBP1-PLK1 axis promotes tumor cell mitosis and impairs trastuzumab sensitivity to gastric cancer.
Shi W, Zhang G, Ma Z, Li L, Liu M, Qin L, Yu Z, Zhao L, Liu Y, Zhang X, Qin J, Ye H, Jiang X, Zhou H, Sun H, Jiao Z
Nature communications 2021 May 14;12(1):2812
Nature communications 2021 May 14;12(1):2812
Stimuli-Responsive and Highly Penetrable Nanoparticles as a Multifunctional Nanoplatform for Boosting Nonsmall Cell Lung Cancer siRNA Therapy.
Shi M, Wang Y, Zhao X, Zhang J, Hu H, Qiao M, Zhao X, Chen D
ACS biomaterials science & engineering 2021 Jul 12;7(7):3141-3155
ACS biomaterials science & engineering 2021 Jul 12;7(7):3141-3155
CDK1-PLK1/SGOL2/ANLN pathway mediating abnormal cell division in cell cycle may be a critical process in hepatocellular carcinoma.
Li L, Huang K, Zhao H, Chen B, Ye Q, Yue J
Cell cycle (Georgetown, Tex.) 2020 May;19(10):1236-1252
Cell cycle (Georgetown, Tex.) 2020 May;19(10):1236-1252
PLK1 Inhibition alleviates transplant-associated obliterative bronchiolitis by suppressing myofibroblast differentiation.
Yu J, Xu H, Cui J, Chen S, Zhang H, Zou Y, Zhao J, Le S, Jiang L, Chen Z, Liu H, Zhang D, Xia J, Wu J
Aging 2020 Jun 15;12(12):11636-11652
Aging 2020 Jun 15;12(12):11636-11652
PHF7 is a novel histone H2A E3 ligase prior to histone-to-protamine exchange during spermiogenesis.
Wang X, Kang JY, Wei L, Yang X, Sun H, Yang S, Lu L, Yan M, Bai M, Chen Y, Long J, Li N, Li D, Huang J, Lei M, Shao Z, Yuan W, Zuo E, Lu K, Liu MF, Li J
Development (Cambridge, England) 2019 Jul 10;146(13)
Development (Cambridge, England) 2019 Jul 10;146(13)
Translation control of the immune checkpoint in cancer and its therapeutic targeting.
Xu Y, Poggio M, Jin HY, Shi Z, Forester CM, Wang Y, Stumpf CR, Xue L, Devericks E, So L, Nguyen HG, Griselin A, Gordan JD, Umetsu SE, Reich SH, Worland ST, Asthana S, Barna M, Webster KR, Cunningham JT, Ruggero D
Nature medicine 2019 Feb;25(2):301-311
Nature medicine 2019 Feb;25(2):301-311
pH-responsive hybrid nanoparticle with enhanced dissociation characteristic for siRNA delivery.
Shi M, Zhao X, Zhang J, Pan S, Yang C, Wei Y, Hu H, Qiao M, Chen D, Zhao X
International journal of nanomedicine 2018;13:6885-6902
International journal of nanomedicine 2018;13:6885-6902
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
Song H, Guo T, Zhao Z, Wei Y, Luo H, Weng W, Zhang R, Zhong M, Chen C, Su J, Shen W
Biomaterials 2018 Sep;178:23-35
Biomaterials 2018 Sep;178:23-35
Impact of iASPP on chemoresistance through PLK1 and autophagy in ovarian clear cell carcinoma.
Chan KK, Wong OG, Wong ES, Chan KK, Ip PP, Tse KY, Cheung AN
International journal of cancer 2018 Sep 15;143(6):1456-1469
International journal of cancer 2018 Sep 15;143(6):1456-1469
Effects of PLK1 on proliferation, invasion and metastasis of gastric cancer cells through epithelial-mesenchymal transition.
Song R, Hou G, Yang J, Yuan J, Wang C, Chai T, Liu Z
Oncology letters 2018 Nov;16(5):5739-5744
Oncology letters 2018 Nov;16(5):5739-5744
53BP1 and BRCA1 control pathway choice for stalled replication restart.
Xu Y, Ning S, Wei Z, Xu R, Xu X, Xing M, Guo R, Xu D
eLife 2017 Nov 6;6
eLife 2017 Nov 6;6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A375 cells were subjected to SDS PAGE followed by western blot with 10305-1-AP(PLK1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 10305-1-AP(PLK1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PLK1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PLK1. This antibody recognizes human,mouse,rat antigen. The PLK1 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
