Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN360333 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Polo-Like Kinase 1 (PLK1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PLK1.
- Description
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references M phase-specific phosphorylation of BRCA2 by Polo-like kinase 1 correlates with the dissociation of the BRCA2-P/CAF complex.
Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis.
The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain.
The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex.
Repression of mRNA for the PLK cell cycle gene after DNA damage requires BRCA1.
Lin HR, Ting NS, Qin J, Lee WH
The Journal of biological chemistry 2003 Sep 19;278(38):35979-87
The Journal of biological chemistry 2003 Sep 19;278(38):35979-87
Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis.
Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg EA, Mayer TU, Barr FA
The Journal of cell biology 2003 Sep 1;162(5):863-75
The Journal of cell biology 2003 Sep 1;162(5):863-75
The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain.
Elia AE, Rellos P, Haire LF, Chao JW, Ivins FJ, Hoepker K, Mohammad D, Cantley LC, Smerdon SJ, Yaffe MB
Cell 2003 Oct 3;115(1):83-95
Cell 2003 Oct 3;115(1):83-95
The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex.
Cheng KY, Lowe ED, Sinclair J, Nigg EA, Johnson LN
The EMBO journal 2003 Nov 3;22(21):5757-68
The EMBO journal 2003 Nov 3;22(21):5757-68
Repression of mRNA for the PLK cell cycle gene after DNA damage requires BRCA1.
Ree AH, Bratland A, Nome RV, Stokke T, Fodstad Ø
Oncogene 2003 Dec 4;22(55):8952-5
Oncogene 2003 Dec 4;22(55):8952-5
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