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- Immunoprecipitation [1]
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- Product number
- 11242-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11242-1-AP, RRID:AB_2085278
- Product name
- COXIV antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated COXIV antibody (Cat. #11242-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references Metformin Attenuates Osteoarthritis Progression by Modulating Mitochondrial Dynamics via Activation of the AMPK/Drp1 Pathway.
The YY1-KIF15-PRDX1 axis promotes gastric cancer progression by inducing mitochondrial ROS imbalance.
Curcumin augments mitophagy via Nrf2-PINK1-mediated, Parkin-dependent ubiquitination to suppress ferroptosis in post-cardiac arrest brain injury.
Osteoblast-derived osteomodulin restrains osteoclastogenesis via ITGB8/RRM2-mediated reduction of mitochondrial respiration and mitochondrial ATP production.
BNIP3L-Mediated Mitophagy Inhibits Cadmium-Induced Apoptosis in the Rat Cerebral Cortex.
NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2.
Complement 5a receptor 2 attenuates diabetic kidney disease by promoting mitochondria-associated endoplasmic reticulum membrane formation mediated by PSS-MFN2 interaction.
NAD+ subcellular partitioning mediated by miR-183 and miR-96 regulates muscle stem cell differentiation.
S100A11 regulates microglial inflammatory response in neuropathic pain via H3K27ac-TFEB-mitochondrial autophagy axis.
Qiang-Xin 1 formula improves cardiac function and alleviates myocardial injury in lipopolysaccharide-induced septic mice by activating calcium/calmodulin-dependent protein kinase I-mediated mitophagy.
Paeoniflorin mitigates myocardial hypertrophy by regulating mitophagy and ferroptosis mediated by mitochondria-associated AMPK-Parkin-ACSL4 pathway.
Echinacoside modulates PARP14-GLUD1 axis to mediate energy metabolism reprogramming and mitochondrial function in diminished ovarian reserve.
COX17 Attenuates Diabetes-Associated Retinal Injury by Improving Mitochondrial Function.
Hyperuricemia exacerbates acetaminophen hepatotoxicity via JNK activation and mitophagy reduction.
Sphinganine-induced lysosomal membrane permeabilization: Interplay with subcellular oxidative levels.
Targeting PAK4 promotes Gemcitabine-induced pyroptosis in pancreatic cancer via NLRP1/caspase-3/GSDME axis.
BNIP3-mediated mitophagy alleviates traumatic brain injury by inhibiting neuronal apoptosis and oxidative stress.
Mechano-matching hydrogel patch promotes myocardial infarction repair via YAP-Bcl-2 pathway activation.
p62/SQSTM1 Condensation Modulates Mitochondrial Clustering to Participate in Mitochondrial Quality Control.
A Novel CYP2E1 Inhibitor, 4-Methyl-5-Acetylthiazole (Q11), Alleviates Obesity Via Modulating Adipose Inflammation and Mitochondrial Dysfunction.
Ginsenoside Rg5 Targets PRDX1 to Disrupt Redox Homeostasis and Induce Mitochondria-Dependent Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells.
Discovery of α-carboline fused benzofuran-containing anticancer agents as rapid apoptosis inducers through intrinsic pathway.
PM(10) Disrupts Mitochondrial Homeostasis in Corneal Epithelial Cells: Protective Effects of SKQ1.
Novel mechanism of neuronal hypoxia response: HIF-1α/STOML2 mediated PINK1-dependent mitophagy activation against neuronal injury.
Integrative Proteomic and Bioenergetic Profiling Reveals Diet- and Strain-Specific Mitochondrial Dysfunction in Cohen Diabetic Rat Hearts.
Mast Cell Chymase and Human Lung Fibroblast Interaction: Mechanisms and Implications for Asthma.
FABP4 is highly expressed in preeclamptic placentas and regulates trophoblast lipid metabolism, mitochondrial function, and oxidative stress in vitro.
Urolithin A alleviates vascular remodeling through mitochondrial SIRT3-mediated SOD2 deacetylation and antioxidation in hypertensive rats.
Renal-targeted tFNA-TPP nanoagonist treats acute kidney injury by amplifying mitophagy.
Zinc Overload in Microvessels Contributes to Blood-Brain Barrier Disruption by Activating the JAK2 Pathway After Cerebral Ischemia/Reperfusion.
Celastrol triggers CAV-1-mediated mitochondrion cholesterol metabolism and mitophagy to suppress liver cancer.
A tumor-derived mitochondrial tsRNA drives vascular invasion of lung adenocarcinoma by promoting ribosomal assembly in endothelial cells.
Small-molecule binding-site discovery using silyl ether-enabled chemoproteomics.
Translocator protein in touch with mitochondrial chloride intracellular channel CLIC5.
Enterovirus A71 3AB protein facilitates immune evasion by blocking cGAS recognition of mtDNA.
Autophagy cargo profiles in skeletal muscle during starvation and exercise.
Role of VDAC1 in hepatocyte apoptosis during acute liver injury in rats induced by obstructive jaundice.
A method for isolating and cryopreserving intact mitochondria with improved integrity and functionality.
Metformin Alleviates Liver Metabolic Dysfunction in Polycystic Ovary Syndrome by Activating the Ethe1/Keap1/PINK1 Pathway.
Ganglioside GA2-mediated caspase-11 activation drives macrophage pyroptosis aggravating intimal hyperplasia after arterial injury.
Voluntarily wheel running protects doxorubicin-induced kidney injury by inhibiting oxidative stress through mitochondrial function.
Low-dose radiation ameliorates doxorubicin-induced renal injury via reducing oxidative stress and protecting mitochondrial function.
TRAP1 Improves Diabetic Retinopathy by Preserving Mitochondrial Function.
MK-4 Ameliorates Diabetic Osteoporosis in Angiogenesis-Dependent Bone Formation by Promoting Mitophagy in Endothelial Cells.
Calcium dysregulation disrupts mitochondrial homeostasis by interfering AMPK/Drp1 pathway to aggravate plaque progression and instability.
Detyrosinated α-tubulin mediates mitochondrial dysfunction and diastolic impairment in heart failure with preserved ejection fraction.
RFX2-BNIP3 axis-driven adaptive mitophagy promotes resistance to ACK1-targeted therapy in non-small cell lung cancer.
Oxidative stress-induced decreased expression of FABP5 leads to mitochondrial damage and survival disorder of decidual stromal cells in women with recurrent spontaneous abortion.
METTL14 promotes TBK1 mRNA stability through IGF2BP3-recognized m6A modification and enhances mitophagy in BMSCs.
Prepubertal Diabetes Stagnates Testicular Development by Skewing Autophagy Homeostasis in Leydig Cells.
HMGA2/PHGDH axis-mediated glycolysis under hypoxia is required for cadmium-induced A549 cell migration.
Galectin-3 gene deletion alters lipid profile in healthy and cardiomyopathy mouse hearts.
TRAP1 inhibits KANSL3 acetylation to alleviate mitochondrial dysfunction by promoting mitophagy in cardiomyocytes under diabetic conditions.
Identification of diagnostic biomarkers and mitochondrial metabolic characteristics in sepsis-associated acute kidney injury.
PTEN-L dephosphorylates Parkin and Ub Ser65 to aggravate mitophagy dysfunction in prion disease cell models.
Bioenergetics of cancer cells: insights into the Warburg effect and regulation of ATP synthase.
The ubiquitin-binding protein ANKRD13A mediates VCP-dependent mitochondrial outer membrane rupture during PINK1/Parkin-mediated mitophagy.
Targeting LARP1 to mitigate aging in lens epithelial cells: mechanistic insights into mitochondrial dysfunction.
Kindlin-1 promotes mitophagy by inhibiting PINK1 degradation to enhance hepatocellular carcinoma progression and modulates sensitivity to donafenib.
Galectin-3 directs mitophagy in response to Parkin-/proteasome-dependent rupture of mitochondrial outer membrane.
Elucidation of puberulic acid-induced nephrotoxicity using stem cell-based kidney organoids.
Kaempferol attenuated LPS-induced microglial neurotoxicity by promoting mitophagy to inhibit mtDNA-mediated NLRP3 inflammasome activation.
Xingnao jianshen prescription reduces mitochondrial cristae breakage by protecting GPX1 from oxidation against cerebral ischemia-reperfusion injury.
Human OPN-derived peptide SV prevents BPD model through interacting with KIF5B to repair mitochondrial damage and inhibit apoptosis.
Ginsenoside Rh2 as a novel PIN1 inhibitor disrupting the cancer stem cell-like phenotype in non-small cell lung cancer.
Dental pulp stem cells alleviate Schwann cell pyroptosis via mitochondrial transfer to enhance facial nerve regeneration.
Daidzein Attenuates Cadmium-Induced Neurotoxicity via Inhibiting Apoptosis and Mitophagy in the Cerebral Cortex of Sprague-Dawley Rats.
Syntaxin 17 Translocation Mediated Mitophagy Switching Drives Hyperglycemia-Induced Vascular Injury.
Mitochondrial Genome-Encoded lncND5 Regulates Mitophagy in Hypoxic Pulmonary Artery Smooth Muscle Cell.
Overexpression of c-Myc triggers p62 aggregation-mediated mitochondrial mitophagy in cabozantinib resistance of hepatocellular carcinoma.
Targeting mitochondrial complex I of CD177(+) neutrophils alleviates lung ischemia-reperfusion injury.
USP14 inhibits mitophagy and promotes tumorigenesis and chemosensitivity through deubiquitinating BAG4 in microsatellite instability-high colorectal cancer.
Retroviral foamy virus gag induces parkin-dependent mitophagy.
Acid-Triggered Cascaded Responsive Supramolecular Peptide Alleviates Myocardial Ischemia‒Reperfusion Injury by Restoring Redox Homeostasis and Protecting Mitochondrial Function.
Novel biallelic TK2 mutations cause mitochondrial DNA depletion syndrome with infantile early-onset lipid storage myopathy.
PNPLA6 regulates retinal homeostasis by choline through phospholipid turnover.
CHCHD2 rescues the mitochondrial dysfunction in iPSC-derived neurons from patient with Mohr-Tranebjaerg syndrome.
Inner Mitochondrial Membrane Peptidase 2-Like Deletion Aggravates Mitochondrial Apoptosis and Inhibits Autophagy After Hyperglycemia Stroke.
Resveratrol Inhibits VDAC1-Mediated Mitochondrial Dysfunction to Mitigate Pathological Progression in Parkinson's Disease Model.
α‑ketoglutarate protects against septic cardiomyopathy by improving mitochondrial mitophagy and fission.
The mitochondrial protease ClpP is a promising target for multiple myeloma treatment.
PFOS causes lysosomes-regulated mitochondrial fission through TRPML1-VDAC1 and oligomerization of MCU/ATP5J2.
STING-mediated mitochondrial DNA release exacerbates PANoptosis in liver ischemia reperfusion injury.
Pyruvate metabolism enzyme DLAT promotes tumorigenesis by suppressing leucine catabolism.
Antihypertensive Drug Amlodipine Besylate Shows Potential in Alleviating Diabetic Peripheral Neuropathy.
Corticosterone induces fatty liver syndrome in chickens via glucocorticoid receptor and inhibition of mitochondrial supercomplex formation.
Homocysteine induced N(6)-methyldeoxyadenosine modification perturbation elicits mitochondria dysfunction contributes to the impairment of learning and memory ability caused by early life stress in rats.
Gut microbiota-bile acid crosstalk contributes to calcium oxalate nephropathy through Hsp90α-mediated ferroptosis.
Harnessing tissue-derived mitochondria-rich extracellular vesicles (Ti-mitoEVs) to boost mitochondrial biogenesis for regenerative medicine.
Poldip2 Aggravates inflammation in diabetic retinopathy by impairing mitophagy via the AMPK/ULK1/Pink1 pathway.
Fatty Acid Metabolism via CPT1A Supports Poll Gland Function and Rutting Activities in Male Bactrian Camels.
Astroglial membrane camouflaged Ptbp1 siRNA delivery hinders glutamate homeostasis via SDH/Nrf2 pathway.
Isoliquiritin targeting m5C RNA methylation improves mitophagy in doxorubicin-induced myocardial cardiotoxicity.
Impaired Iron-Sulfur Cluster Synthesis Induces Mitochondrial PARthanatos in Diabetic Cardiomyopathy.
Ubiquitin specific peptidase 11 knockdown slows Huntington's disease progression via regulating mitochondrial dysfunction and neuronal damage depending on PTEN-mediated AKT pathway.
Aristolochic acid I induced mitochondrial Ca(2+) accumulation triggers the production of MitoROS and activates Src/FAK pathway in hepatocellular carcinoma cells.
Sirtuin-1 Regulates Mitochondrial Calcium Uptake Through Mitochondrial Calcium Uptake 1 (MICU1).
Idebenone Protects Photoreceptors Impaired by Oxidative Phosphorylation Disorder in Retinal Detachment.
OPA3 inhibits the cGAS-STING pathway mediated by mtDNA stress to promote colorectal cancer progression.
Nonenzymatic lysine D-lactylation induced by glyoxalase II substrate SLG dampens inflammatory immune responses.
CD24 flags anastasis in melanoma cells.
Aβ -induced excessive mitochondrial fission drives type H blood vessels injury to aggravate bone loss in APP/PS1 mice with Alzheimer's diseases.
β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy.
Zn(2 +) alleviates ischemia/reperfusion injury in H9c2 cells by modulating mitochondrial biogenesis and dynamics via MCU.
Porphyromonas gingivalis Induces Endothelial Dysfunction Through Sirt3-Dependent CypD Acetylation.
Vitexin enhances mitophagy and improves renal ischemia-reperfusion injury by regulating the p38/MAPK pathway.
RAB3GAP2 silencing alleviates oxidative stress in cataracts by enhancing Mfn2-mediated mitochondrial autophagy by activating JNK/STAT3.
Naringenin boosts Parkin-mediated mitophagy via estrogen receptor alpha to maintain mitochondrial quality control and heal diabetic foot ulcer.
Hispolon reduces mitochondrial dysfunction and improves fibrosis of diabetes nephropathy by activating AMPK signal and inhibiting mPTP opening.
Kaempferol exerts anti-colorectal cancer effects through its multi-target mediated glucose metabolism remodeling.
LRPPRC-Driven Oxidative Phosphorylation Is Associated with Elesclomol-Induced Cuproptosis in Ovarian Cancer.
Uptake mechanisms and functions of isolated mitochondria in mesenchymal stromal cells.
LncRNA-encoded peptide LRRC75A-AS1-ORF3 suppresses anti-tumor immunity in colorectal cancer through mitophagy-mediated attenuation of cGAS-STING signaling.
Ginsenoside Rh2 inhibits mesenchymal stem cell senescence by regulating mitochondrial and lysosomal function.
High matrix stiffness triggers the YAP-OPA1-TET1/3 loop to drive chemoresistance via enhanced nuclear-mitochondrial communication.
Lactate mitochondrial oxidation drives stemness potential in metastatic breast cancer.
Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity.
The DRP1 inhibitory peptide P110 provides neuroprotection after subarachnoid hemorrhage by suppressing neuronal apoptosis and stabilizing the blood-brain barrier.
Ceftriaxone alleviates mitochondrial damage through the inhibition of extrasynaptic NMDA receptor-mediated changes in intracellular calcium levels to improve cognitive deficits in APP/PS1 mice.
A novel modulator of IL-6R prevents inflammation-induced preterm birth and improves newborn outcome.
RONIN/HCF1-TFEB Axis Protects Against D-Galactose-Induced Cochlear Hair Cell Senescence Through Autophagy Activation.
c-FLIP Protects Cardiac Microcirculation in Sepsis-Induced Myocardial Dysfunction Via FUNDC1-Mediated Regulation of Mitochondrial Autophagy.
Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming.
RNA triggers chronic stress during neuronal aging.
Ankyrin-B modulates mitochondrial fission in skeletal muscle and is required for optimal endurance exercise capacity.
Dual-key cooperatively activated DNA regulator for controlling mitochondria-lysosome interactions.
MRPL13 enhances mitochondrial function and promotes tumor progression in ovarian cancer by inhibiting mPTP opening via SLC25A6.
PGAM5 aggravated doxorubicin-induced cardiotoxicity by disturbing mitochondrial dynamics and exacerbating cardiomyocytes apoptosis.
Olfactory mucosa mesenchymal stem cell-derived exosomes protect against neuroinflammation after subarachnoid hemorrhage by activating mitophagy.
Targeting SARM1 as a novel neuroprotective therapy in neurotropic viral infections.
Loss of lipid droplet-mitochondria contacts confers protection against ethanol-induced cardiotoxicity.
Microvesicles carrying EV71 virions cross BBB through endocytic pathway to induce brain injury.
Alda-1 mediates cell senescence and counteracts bone loss in weightlessness through regulating mitophagy.
Hypoxia-preconditioned bone marrow-derived mesenchymal stem cells protect neurons from cardiac arrest-induced pyroptosis.
REGγ deficiency ameliorates hepatic ischemia and reperfusion injury in a mitochondrial p66shc dependent manner in mice.
Schisandrin a Ameliorates Cardiac Injury and Dysfunction Induced by Hemorrhagic Shock via Activating the Nrf2 Signaling Pathway.
A liver-fat crosstalk for iron flux during healthy beiging of adipose tissue.
Jagged 2 inhibition attenuates hypoxia-induced mitochondrial damage and pulmonary hypertension through Sirtuin 1 signaling.
Mitochondria-Rich Microvesicles Alleviate CNI ED by Transferring Mitochondria and Suppressing Local Ferroptosis.
5-Methoxytryptophan Alleviates Lipopolysaccharide-Induced Acute Kidney Injury by Regulating Nrf2-Mediated Mitophagy.
NLRP3 Inflammasome Deficiency Alleviates Inflammation and Oxidative Stress by Promoting PINK1/Parkin-Mediated Mitophagy in Allergic Rhinitis Mice and Nasal Epithelial Cells.
Novel bi-allelic DNAH3 variants cause oligoasthenoteratozoospermia.
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux.
The mitochondria‒paraspeckle axis regulates the survival of transplanted stem cells under oxidative stress conditions.
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
β-arrestin1 protects intestinal tight junction through promoting mitofusin 2 transcription to drive parkin-dependent mitophagy in colitis.
Melatonin Alleviates Osteoarthritis by Regulating NADPH Oxidase 4-Induced Ferroptosis and Mitigating Mitochondrial Dysfunction.
HSPB8 attenuates lipopolysaccharide‑mediated acute lung injury in A549 cells by activating mitophagy.
LONP1 alleviates ageing-related renal fibrosis by maintaining mitochondrial homeostasis.
The one-carbon metabolic enzyme MTHFD2 promotes resection and homologous recombination after ionizing radiation.
Cocoa extract induces browning of white adipocytes and improves glucose intolerance in mice fed a high-fat diet.
Substrate-Mediated Regulation of Src Expression Drives Osteoclastogenesis Divergence.
Strategically engineered Au(I) complexes for orchestrated tumor eradication via chemo-phototherapy and induced immunogenic cell death.
Glucose-1,6-bisphosphate: A new gatekeeper of cerebral mitochondrial pyruvate uptake.
Mitochondrial Dysfunction due to Novel COQ8A Variation with Poor Response to CoQ10 Treatment: A Comprehensive Study and Review of Literatures.
Low-dose radiation promotes high-fat diet-induced atherosclerosis by activating cGAS signal pathway.
CHIP drives proteasomal degradation of NUR77 to alleviate oxidative stress and intrinsic apoptosis in cisplatin-induced nephropathy.
Mitochondrial fatty acid oxidation drives senescence.
Reduced expression of NUPR1 alleviates epilepsy progression via attenuating ER stress.
TRPC6-Calpain-1 Axis Promotes Tubulointerstitial Inflammation by Inhibiting Mitophagy in Diabetic Kidney Disease.
Long non-coding RNA MALAT1 triggers ferroptosis via interaction with FUS to enhance ACSF2 mRNA stabilization in septic acute kidney injury.
The PRMT6/STAT1/ACSL1 axis promotes ferroptosis in diabetic nephropathy.
Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity.
Emodin alleviates lung injury via the miR-217-5p/Sirt1 axis in rats with severe acute pancreatitis.
Taurine hypomodification underlies mitochondrial tRNATrp-related genetic diseases.
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells.
Endurance training increases mitochondrial myoglobin and enhances its interaction with complex IV in rat plantaris muscle.
Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia.
MicroRNA-142-3p alleviated high salt-induced cardiac fibrosis via downregulating optineurin-mediated mitophagy.
Pirin Inhibits FAS-Mediated Apoptosis to Support Colorectal Cancer Survival.
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
Metformin switches cell death modes to soothe the apical periodontitis via ZBP1.
Proteomic analysis of mitochondria associated membranes in renal ischemic reperfusion injury.
Atox1 protects hippocampal neurons after traumatic brain injury via DJ-1 mediated anti-oxidative stress and mitophagy.
Time of exercise differentially impacts bone growth in mice.
Maternal Ezh1/2 deficiency impairs the function of mitochondria in mouse oocytes and early embryos.
Targeting NKAα1 to treat Parkinson's disease through inhibition of mitophagy-dependent ferroptosis.
Cytochrome c oxidase IV isoform 1 (COX4-1) regulates the proliferation, migration and invasion of trophoblast cells via modulating mitochondrial function.
Targeting DRP1 with Mdivi-1 to correct mitochondrial abnormalities in ADOA+ syndrome.
MYG1 drives glycolysis and colorectal cancer development through nuclear-mitochondrial collaboration.
Static magnetic field-modulated mesenchymal stem cell-derived mitochondria-containing microvesicles for enhanced intervertebral disc degeneration therapy.
Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation.
Tafazzin mediates tamoxifen resistance by regulating cellular phospholipid composition in ER-positive breast cancer.
Suppression of NLRP3 inflammasome activation by astragaloside IV via promotion of mitophagy to ameliorate radiation-induced renal injury in mice.
AKT1 phosphorylation of cytoplasmic ME2 induces a metabolic switch to glycolysis for tumorigenesis.
Network pharmacology and experimental validation on yangjing zhongyu decoction against diminished ovarian reserve.
Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer's Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice.
Axonal injury mediated by neuronal p75NTR/TRAF6/JNK pathway contributes to cognitive impairment after repetitive mTBI.
Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis.
A new andrographolide derivative ADA targeting SIRT3-FOXO3a signaling mitigates cognitive impairment by activating mitophagy and inhibiting neuroinflammation in Apoe4 mice.
AMPK phosphorylation of FNIP1 (S220) controls mitochondrial function and muscle fuel utilization during exercise.
SERCA2 dysfunction triggers hypertension by interrupting mitochondrial homeostasis and provoking oxidative stress.
Zbtb16 increases susceptibility of atrial fibrillation in type 2 diabetic mice via Txnip-Trx2 signaling.
Sacubitril/valsartan ameliorates tubulointerstitial fibrosis by restoring mitochondrial homeostasis in diabetic kidney disease.
PX-478 induces apoptosis in acute myeloid leukemia under hypoxia by inhibiting the PI3K/AKT/mTOR pathway through downregulation of GBE1.
Regulatory roles of histamine receptor in astrocytic glutamate clearance under conditions of increased glucose variability.
New TIPARP inhibitor rescues mitochondrial function and brain injury in ischemic stroke.
Protein kinase N1 deficiency results in upregulation of cerebral energy metabolism and is highly protective in in vivo and in vitro stroke models.
Ginsenoside compound K alleviates brain aging by inhibiting ferroptosis through modulation of the ASK1-MKK7-JNK signaling pathway.
Targeting BRIX1 via Engineered Exosomes Induces Nucleolar Stress to Suppress Cancer Progression.
Conjugated fatty acids drive ferroptosis through chaperone-mediated autophagic degradation of GPX4 by targeting mitochondria.
Subcellular Proteomic Mapping of Lysine Lactylation.
Boosting neuronal activity-driven mitochondrial DNA transcription improves cognition in aged mice.
Lysosomes drive the piecemeal removal of mitochondrial inner membrane.
The VDAC1 oligomerization regulated by ATP5B leads to the NLRP3 inflammasome activation in the liver cells under PFOS exposure.
PGC-1α/LDHA signaling facilitates glycolysis initiation to regulate mechanically induced bone remodeling under inflammatory microenvironment.
Comparison of the stage-dependent mitochondrial changes in response to pressure overload between the diseased right and left ventricle in the rat.
Carcinoma-associated mesenchymal stem cells promote ovarian cancer heterogeneity and metastasis through mitochondrial transfer.
Queuine ameliorates impaired mitochondrial function caused by mt-tRNA(Asn) variants.
DsbA-L ameliorates renal aging and renal fibrosis by maintaining mitochondrial homeostasis.
SIRT3 alleviates painful diabetic neuropathy by mediating the FoxO3a-PINK1-Parkin signaling pathway to activate mitophagy.
Resveratrol Inhibits Zinc Deficiency-Induced Mitophagy and Exerts Cardiac Cytoprotective Effects.
The surface morphology of Atractylodes macrocephala polysaccharide and its inhibitory effect on PCV2 replication.
Taurine ameliorates sensorimotor function by inhibiting apoptosis and activating A2 astrocytes in mice after subarachnoid hemorrhage.
Cardiolipin externalization mediates prion protein (PrP) peptide 106-126-associated mitophagy and mitochondrial dysfunction.
A novel mutation in CFAP47 causes male infertility due to multiple morphological abnormalities of the sperm flagella.
Electroacupuncture preconditioning protects against myocardial ischemia-reperfusion injury by modulating dynamic inflammatory response.
MAVI1, an endoplasmic reticulum-localized microprotein, suppresses antiviral innate immune response by targeting MAVS on mitochondrion.
Ginsenoside Rh4 delays skeletal muscle aging through SIRT1 pathway.
UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture.
Crotonylated BEX2 interacts with NDP52 and enhances mitophagy to modulate chemotherapeutic agent-induced apoptosis in non-small-cell lung cancer cells.
The lysosome-mitochondrion crosstalk engaged in silver nanoparticles-disturbed mitochondrial homeostasis.
Mitochondrial dysfunction and calcium dysregulation in COQ8A-ataxia Purkinje neurons are rescued by CoQ10 treatment.
COX17 restricts renal fibrosis development by maintaining mitochondrial copper homeostasis and restoring complex IV activity.
Kinsenoside mitigates myocardial ischemia/reperfusion-induced ferroptosis via activation of the Akt/Nrf2/HO-1 pathway.
Afzelin protects against doxorubicin-induced cardiotoxicity by promoting the AMPKα/SIRT1 signaling pathway.
Matrix stiffness induces Drp1-mediated mitochondrial fission through Piezo1 mechanotransduction in human intervertebral disc degeneration.
Endoplasmic reticulum-mitochondrial calcium transport contributes to soft extracellular matrix-triggered mitochondrial dynamics and mitophagy in breast carcinoma cells.
Acid ground nano-realgar processed product inhibits breast cancer by inducing mitophagy via the p53/BNIP3/NIX pathway.
Glutathione Might Attenuate Arsenic-Induced Liver Injury by Modulating the Foxa2-XIAP Axis to Reduce Oxidative Stress and Mitochondrial Apoptosis.
Miquelianin in Folium Nelumbinis extract promotes white-to-beige fat conversion via blocking AMPK/DRP1/mitophagy and modulating gut microbiota in HFD-fed mice.
Methylcrotonyl-CoA carboxylase subunit 1 (MCCA) regulates multidrug resistance in multiple myeloma.
Interactome profiling of Crimean-Congo hemorrhagic fever virus glycoproteins.
CX3CR1(hi) macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue.
MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells.
Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats.
RAB7A GTPase Is Involved in Mitophagosome Formation and Autophagosome-Lysosome Fusion in N2a Cells Treated with the Prion Protein Fragment 106-126.
Inhibition of ACSF2 protects against renal ischemia/reperfusion injury via mediating mitophagy in proximal tubular cells.
MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model.
STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing PARL-induced PINK1 degradation.
The immunity-related GTPase IRGC mediates interaction between lipid droplets and mitochondria to facilitate sperm motility.
Toosendanin-induced apoptosis of CMT-U27 is mediated through the mitochondrial apoptotic pathway.
Necroptosis signaling and mitochondrial dysfunction cross-talking facilitate cell death mediated by chelerythrine in glioma.
LINC00493-encoded microprotein SMIM26 exerts anti-metastatic activity in renal cell carcinoma.
SS-31 alleviated nociceptive responses and restored mitochondrial function in a headache mouse model via Sirt3/Pgc-1α positive feedback loop.
5-HEPE reduces obesity and insulin resistance by promoting adipose tissue browning through GPR119/AMPK/PGC1α activation.
Expanding DdCBE-mediated targeting scope to aC motif preference in rat.
Toxicologic pathological mechanism of acute lung injury induced by oral administration of benzalkonium chloride in mice.
Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis.
SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes.
A proximity labeling strategy enables proteomic analysis of inter-organelle membrane contacts.
Ischemia/reperfusion-induced MiD51 upregulation recruits Drp1 to mitochondria and contributes to myocardial injury.
Site-specific ubiquitination of VDAC1 restricts its oligomerization and mitochondrial DNA release in liver fibrosis.
Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma.
Macrophage-derived exosomal miR-195a-5p impairs tubular epithelial cells mitochondria in acute kidney injury mice.
Oligomeric CHMP7 mediates three-way ER junctions and ER-mitochondria interactions.
Increased mitophagy protects cochlear hair cells from aminoglycoside-induced damage.
STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity.
ER stress-enhanced HMGA2 plays an important role in Cr (VI)-induced glycolysis and inhibited oxidative phosphorylation by targeting the transcription of ATF4.
Synthesis of Novel Pentacyclic Triterpenoid Derivatives that Induce Apoptosis in Cancer Cells through a ROS-dependent, Mitochondrial-Mediated Pathway.
Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via regulation of pyruvate dehydrogenase phosphorylation.
Novel ELAC2 Mutations in Individuals Presenting with Variably Severe Neurological Disease in the Presence or Absence of Cardiomyopathy.
Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation.
Cytosolic Release of Mitochondrial DNA and Associated cGAS Signaling Mediates Radiation-Induced Hematopoietic Injury of Mice.
A Missense Variant in AIFM1 Caused Mitochondrial Dysfunction and Intolerance to Riboflavin Deficiency.
Zinc Overload Induces Damage to H9c2 Cardiomyocyte Through Mitochondrial Dysfunction and ROS-Mediated Mitophagy.
Deficiency of aldehyde dehydrogenase 2 aggravates ethanol-induced cytotoxicity in N2a cells via CaMKII/Drp1-mediated mitophagy.
Active fraction of Polyrhachis vicina (Roger) alleviated cerebral ischemia/reperfusion injury by targeting SIRT3-mediated mitophagy and angiogenesis.
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis.
Mitochondrial Protein SLIRP Affects Biosynthesis of Cytochrome c Oxidase Subunits in HEK293T Cells.
Mitochondrion-targeted carboxymethyl chitosan hybrid nanoparticles loaded with Coenzyme Q10 protect cardiac grafts against cold ischaemia‒reperfusion injury in heart transplantation.
CK1δ and CK1ε Signaling Sustains Mitochondrial Metabolism and Cell Survival in Multiple Myeloma.
Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning.
Huoxue Jiedu Recipe represses mitochondrial fission to alleviate submandibular gland inflammation in Sjögren's syndrome.
Lias overexpression alleviates pulmonary injury induced by fine particulate matter in mice.
Polystyrene exacerbates cadmium-induced mitochondrial damage to lung by blocking autophagy in mice.
The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts.
Jionoside A1 alleviates ischemic stroke ischemia/reperfusion injury by promoting Nix-mediated mitophagy.
Flt3 Activation Mitigates Mitochondrial Fragmentation and Heart Dysfunction through Rebalanced L-OPA1 Processing by Hindering the Interaction between Acetylated p53 and PHB2 in Cardiac Remodeling.
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Restoration of mitochondrial function through activation of hypomodified tRNAs with pathogenic mutations associated with mitochondrial diseases.
Loganin alleviated cognitive impairment in 3×Tg-AD mice through promoting mitophagy mediated by optineurin.
Amino acids downregulate SIRT4 to detoxify ammonia through the urea cycle.
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
TOM complex-independent transport pathway of myoglobin into mitochondria in C2C12 myotubes.
Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function.
Tex2 is required for lysosomal functions at TMEM55-dependent ER membrane contact sites.
Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis.
Melatonin ameliorates glyphosate- and hard water-induced renal tubular epithelial cell senescence via PINK1-Parkin-dependent mitophagy.
A conditional knockout rat resource of mitochondrial protein-coding genes via a DdCBE-induced premature stop codon.
Evaluation of Coenzyme Q10 (CoQ10) Deficiency and Therapy in Mouse Models of Cardiomyopathy.
Effect of one-time high load exercise on skeletal muscle injury in rats of different genders: oxidative stress and mitochondrial responses.
San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway.
Claudin-10 overexpression suppresses human clear cell renal cell carcinoma growth and metastasis by regulating ATP5O and causing mitochondrial dysfunction.
B16 Membrane-Coated Vesicles for Combined Photodynamic Therapy and Immunotherapy Shift Immune Microenvironment of Melanoma.
Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction.
The expression pattern of GDF15 in human brain changes during aging and in Alzheimer's disease.
Shenxiong glucose injection inhibits oxidative stress and apoptosis to ameliorate isoproterenol-induced myocardial ischemia in rats and improve the function of HUVECs exposed to CoCl(2).
Inhibition of the PINK1-Parkin Pathway Enhances the Lethality of Sorafenib and Regorafenib in Hepatocellular Carcinoma.
Characterization and subcellular localization of Alongshan virus proteins.
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
Gefitinib facilitates PINK1/Parkin-mediated mitophagy by enhancing mitochondrial recruitment of OPTN.
Ca(2+) channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons.
Kaempferol impairs aerobic glycolysis against melanoma metastasis via inhibiting the mitochondrial binding of HK2 and VDAC1.
Yangjing Zhongyu decoction facilitates mitochondrial activity, estrogenesis, and energy metabolism in H(2)O(2)-induced human granulosa cell line KGN.
CHCHD10 Modulates Thermogenesis of Adipocytes by Regulating Lipolysis.
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42) inhibits cell proliferation and induces apoptosis via inhibiting ALK and its downstream pathways in Karpas299 cells.
Inhibition of High-Temperature Requirement Protein A2 Protease Activity Represses Myogenic Differentiation via UPRmt.
Protective effect of low-dose radiation on doxorubicin-induced brain injury in mice.
Mitophagy induced by classical swine fever virus nonstructural protein 5A promotes viral replication.
CGG repeat expansion in NOTCH2NLC causes mitochondrial dysfunction and progressive neurodegeneration in Drosophila model.
HMGA2 mediates Cr (VI)-induced metabolic reprogramming through binding to mitochondrial D-Loop region.
GRP75 Modulates Endoplasmic Reticulum-Mitochondria Coupling and Accelerates Ca(2+)-Dependent Endothelial Cell Apoptosis in Diabetic Retinopathy.
Nuclear Receptor NR1D1 Regulates Abdominal Aortic Aneurysm Development by Targeting the Mitochondrial Tricarboxylic Acid Cycle Enzyme Aconitase-2.
CircRNA Samd4 induces cardiac repair after myocardial infarction by blocking mitochondria-derived ROS output.
Pentatricopeptide Protein PTCD2 Regulates COIII Translation in Mitochondria of the HeLa Cell Line.
Mitochondrial apolipoprotein A-I binding protein alleviates atherosclerosis by regulating mitophagy and macrophage polarization.
The MFN1 and MFN2 mitofusins promote clustering between mitochondria and peroxisomes.
FNIP1 regulates adipocyte browning and systemic glucose homeostasis in mice by shaping intracellular calcium dynamics.
Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas.
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.
Sheng Mai San ameliorated heat stress-induced liver injury via regulating energy metabolism and AMPK/Drp1-dependent autophagy process.
Ubiquitylation of cyclin C by HACE1 regulates cisplatin-associated sensitivity in gastric cancer.
LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Acetaldehyde Induces Cytotoxicity via Triggering Mitochondrial Dysfunction and Overactive Mitophagy.
Long-term exercise pre-training attenuates Alzheimer's disease-related pathology in a transgenic rat model of Alzheimer's disease.
Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations.
An elemental diet protects mouse salivary glands from 5-fluorouracil-induced atrophy.
Inhibition of Drp1 ameliorates diabetic retinopathy by regulating mitochondrial homeostasis.
Maternal Herpesviridae infection during pregnancy alters midbrain dopaminergic signatures in adult offspring.
Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4.
Disrupted mitochondrial homeostasis coupled with mitotic arrest generates antineoplastic oxidative stress.
Extracellular vesicles derived from endothelial cells in hypoxia contribute to pulmonary artery smooth muscle cell proliferation in-vitro and pulmonary hypertension in mice.
Dopamine receptor D1 signaling stimulates lipolysis and browning of white adipocytes.
Theobromine enhances the conversion of white adipocytes into beige adipocytes in a PPARγ activation-dependent manner.
Phenotypic and genotypic changes in obesity and type 2 diabetes of male KK mice with aging.
Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis.
PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.
Protein C receptor maintains cancer stem cell properties via activating lipid synthesis in nasopharyngeal carcinoma.
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy.
The Absence of Parkin Does Not Promote Dopamine or Mitochondrial Dysfunction in PolgA(D257A/D257A) Mitochondrial Mutator Mice.
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
Glyphosate-induced mitochondrial reactive oxygen species overproduction activates parkin-dependent mitophagy to inhibit testosterone synthesis in mouse leydig cells.
Calenduloside E alleviates cerebral ischemia/reperfusion injury by preserving mitochondrial function.
Direct Analysis of Mitochondrial Damage Caused by Misfolded/Destabilized Proteins.
HIF-1α mediates renal fibrosis by regulating metabolic remodeling of renal tubule epithelial cells.
N(6)-adenomethylation of GsdmC is essential for Lgr5(+) stem cell survival to maintain normal colonic epithelial morphogenesis.
Ketogenesis acts as an endogenous protective programme to restrain inflammatory macrophage activation during acute pancreatitis.
Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells.
Role of molybdenum in material immunomodulation and periodontal wound healing: Targeting immunometabolism and mitochondrial function for macrophage modulation.
Brown adipose tissue involution associated with progressive restriction in progenitor competence.
Microcystin-leucine arginine (MC-LR) induces mouse ovarian inflammation by promoting granulosa cells to produce inflammatory cytokine via activation of cGAS-STING signaling.
Adipose-derived stem cells alleviate liver injury induced by type 1 diabetes mellitus by inhibiting mitochondrial stress and attenuating inflammation.
TGR5 Activation Ameliorates Mitochondrial Homeostasis via Regulating the PKCδ/Drp1-HK2 Signaling in Diabetic Retinopathy.
PINK1 Alleviates Cognitive Impairments via Attenuating Pathological Tau Aggregation in a Mouse Model of Tauopathy.
Transcription-Based Multidimensional Regulation of Fatty Acid Metabolism by HIF1α in Renal Tubules.
Phosphorylation of Dynamin-Related Protein 1 (DRP1) Regulates Mitochondrial Dynamics and Skeletal Muscle Wasting in Cancer Cachexia.
Mutations in RNA Methyltransferase Gene NSUN5 Confer High Risk of Outflow Tract Malformation.
Samm50 Promotes Hypertrophy by Regulating Pink1-Dependent Mitophagy Signaling in Neonatal Cardiomyocytes.
Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy.
Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke.
Tubeimoside I Ameliorates Myocardial Ischemia-Reperfusion Injury through SIRT3-Dependent Regulation of Oxidative Stress and Apoptosis.
Inhibition of α-Synuclein Accumulation Improves Neuronal Apoptosis and Delayed Postoperative Cognitive Recovery in Aged Mice.
miRNA-27a Transcription Activated by c-Fos Regulates Myocardial Ischemia-Reperfusion Injury by Targeting ATAD3a.
Inhibition of PI3K/AKT signaling via ROS regulation is involved in Rhein-induced apoptosis and enhancement of oxaliplatin sensitivity in pancreatic cancer cells.
High-Fat Diet-Induced Mitochondrial Dysfunction Promotes Genioglossus Injury - A Potential Mechanism for Obstructive Sleep Apnea with Obesity.
Sympathetic Denervation Ameliorates Renal Fibrosis via Inhibition of Cellular Senescence.
Cordycepin Decreases Ischemia/Reperfusion Injury in Diabetic Hearts via Upregulating AMPK/Mfn2-dependent Mitochondrial Fusion.
Empagliflozin Induces White Adipocyte Browning and Modulates Mitochondrial Dynamics in KK Cg-Ay/J Mice and Mouse Adipocytes.
Antioxidant activity of mesenchymal stem cell-derived extracellular vesicles restores hippocampal neurons following seizure damage.
Gastrodin protects against high glucose-induced cardiomyocyte toxicity via GSK-3β-mediated nuclear translocation of Nrf2.
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Mitochondria transplantation protects traumatic brain injury via promoting neuronal survival and astrocytic BDNF.
PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma.
3D-printing magnesium-polycaprolactone loaded with melatonin inhibits the development of osteosarcoma by regulating cell-in-cell structures.
Sigma-1 receptor regulates mitophagy in dopaminergic neurons and contributes to dopaminergic protection.
A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.
Load-matched acute and chronic exercise induce changes in mitochondrial biogenesis and metabolic markers.
Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca(2+) homeostasis.
Chaperone-mediated autophagy controls the turnover of E3 ubiquitin ligase MARCHF5 and regulates mitochondrial dynamics.
Influence of psychostimulants and opioids on epigenetic modification of class III histone deacetylase (HDAC)-sirtuins in glial cells.
EF24 exerts cytotoxicity against NSCLC via inducing ROS accumulation.
Kir6.2 is essential to maintain neurite features by modulating PM20D1-reduced mitochondrial ATP generation.
Methionine synthase supports tumour tetrahydrofolate pools.
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway.
Preservation of mitochondrial homeostasis is responsible for the ameliorative effects of Suhuang antitussive capsule on non-resolving inflammation via inhibition of NF-κB signaling and NLRP3 inflammasome activation.
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
AMPK-dependent and -independent coordination of mitochondrial function and muscle fiber type by FNIP1.
MiR-133a-3p relieves the oxidative stress induced trophoblast cell apoptosis through the BACH1/Nrf2/HO-1 signaling pathway.
Empagliflozin alleviates ethanol-induced cardiomyocyte injury through inhibition of mitochondrial apoptosis via a SIRT1/PTEN/Akt pathway.
ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.
Enzymatic activation of pyruvate kinase increases cytosolic oxaloacetate to inhibit the Warburg effect.
S100B/RAGE/Ceramide signaling pathway is involved in sepsis-associated encephalopathy.
miR-34a-5p regulates PINK1-mediated mitophagy via multiple modes.
Selenium Deficiency-Induced Damage and Altered Expression of Mitochondrial Biogenesis Markers in the Kidneys of Mice.
OMA1 reprograms metabolism under hypoxia to promote colorectal cancer development.
Neuroprotection against cerebral ischemia/reperfusion by dietary phytochemical extracts from Tibetan turnip (Brassica rapa L.).
The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling.
Bioactivation of clozapine by mitochondria of the murine heart: Possible cause of cardiotoxicity.
MiR-133a-3p relieves the oxidative stress induced trophoblast cell apoptosis through the BACH1/Nrf2/HO-1 signaling pathway.
Remote Ischemic Postconditioning Inhibits Hippocampal Neuronal Apoptosis and Mitophagy After Cardiopulmonary Resuscitation in Rats.
Involvement of miR-27a-3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress.
p53 induces ARTS to promote mitochondrial apoptosis.
Lobetyolin inhibits the proliferation of breast cancer cells via ASCT2 down-regulation-induced apoptosis.
UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma.
SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species.
USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.
Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis.
A novel protoapigenone analog RY10-4 induces apoptosis of breast cancer cells by exacerbating mitochondrial Ca(2+) influx through mitochondrial calcium uniporter.
Docosahexaenoic acid promotes the formation of autophagosomes in MCF-7 breast cancer cells through oxidative stress-induced growth inhibitor 1 mediated activation of AMPK/mTOR pathway.
Cypermethrin induces Sertoli cell apoptosis through mitochondrial pathway associated with calcium.
SESN2 protects against denervated muscle atrophy through unfolded protein response and mitophagy.
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
Protective autophagy attenuates soft substrate-induced apoptosis through ROS/JNK signaling pathway in breast cancer cells.
Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells.
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Bioactive compound from the Tibetan turnip (Brassica rapa L.) elicited anti-hypoxia effects in OGD/R-injured HT22 cells by activating the PI3K/AKT pathway.
Raman Spectroscopic Assessment of Myocardial Viability in Langendorff-Perfused Ischemic Rat Hearts.
The positive regulation loop between NRF1 and NONO-TFE3 fusion promotes phase separation and aggregation of NONO-TFE3 in NONO-TFE3 tRCC.
RGS12 is required for the maintenance of mitochondrial function during skeletal development.
Melatonin Protects Goat Spermatogonial Stem Cells against Oxidative Damage during Cryopreservation by Improving Antioxidant Capacity and Inhibiting Mitochondrial Apoptosis Pathway.
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Hydrogen Sulfide Overproduction Is Involved in Acute Ischemic Cerebral Injury Under Hyperhomocysteinemia.
Lysophosphatidic Acid Induces Apoptosis of PC12 Cells Through LPA1 Receptor/LPA2 Receptor/MAPK Signaling Pathway.
Perindopril Improves Cardiac Function by Enhancing the Expression of SIRT3 and PGC-1α in a Rat Model of Isoproterenol-Induced Cardiomyopathy.
Denervation drives skeletal muscle atrophy and induces mitochondrial dysfunction, mitophagy and apoptosis via miR-142a-5p/MFN1 axis.
DW14006 as a Direct AMPKα Activator Ameliorates Diabetic Peripheral Neuropathy in Mice.
Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy.
Mitochondrial superoxide contributes to oxidative stress exacerbated by DNA damage response in RAD51-depleted ovarian cancer cells.
Dependence of PINK1 accumulation on mitochondrial redox system.
Muscone suppresses inflammatory responses and neuronal damage in a rat model of cervical spondylotic myelopathy by regulating Drp1-dependent mitochondrial fission.
Mcl-1-mediated mitochondrial fission protects against stress but impairs cardiac adaptation to exercise.
Inhibition of miR-181a-5p reduces astrocyte and microglia activation and oxidative stress by activating SIRT1 in immature rats with epilepsy.
Neuroprotective Effect of Piracetam against Cocaine-Induced Neuro Epigenetic Modification of DNA Methylation in Astrocytes.
Immunoprecipitation of Acetyl-lysine And Western Blotting of Long-chain acyl-CoA Dehydrogenases and Beta-hydroxyacyl-CoA Dehydrogenase in Palmitic Acid Treated Human Renal Tubular Epithelial Cells.
DsbA-L mediated renal tubulointerstitial fibrosis in UUO mice.
Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras-Driven Tumor Growth or Metastasis.
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42), a novel ALK inhibitor, induces apoptosis and protective autophagy in H2228 cells.
V-ATPase blockade reduces renal gluconeogenesis and improves insulin secretion in type 2 diabetic rats.
OPA1 and MICOS Regulate mitochondrial crista dynamics and formation.
Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage.
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
Berberine protects against diabetic retinopathy by inhibiting cell apoptosis via deactivation of the NF‑κB signaling pathway.
Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
Inhibition of thioredoxin reductase 1 correlates with platinum-based chemotherapeutic induced tissue injury.
Echinacoside attenuates inflammatory response in a rat model of cervical spondylotic myelopathy via inhibition of excessive mitochondrial fission.
Overexpression of endogenous lipoic acid synthase attenuates pulmonary fibrosis induced by crystalline silica in mice.
The mitochondria-targeted anti-oxidant MitoQ protects against intervertebral disc degeneration by ameliorating mitochondrial dysfunction and redox imbalance.
FSH prevents porcine granulosa cells from hypoxia-induced apoptosis via activating mitophagy through the HIF-1α-PINK1-Parkin pathway.
Dynamic PGAM5 multimers dephosphorylate BCL-xL or FUNDC1 to regulate mitochondrial and cellular fate.
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis.
Quantitative Mitochondrial Proteomics Reveals ANXA7 as a Crucial Factor in Mitophagy.
Drp1, a potential therapeutic target for Parkinson's disease, is involved in olfactory bulb pathological alteration in the Rotenone-induced rat model.
Prenatal High-Salt Diet-Induced Metabolic Disorders via Decreasing Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1α in Adult Male Rat Offspring.
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway.
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.
Mitochondrial miR-181a-5p promotes glucose metabolism reprogramming in liver cancer by regulating the electron transport chain.
Fluoride-induced renal dysfunction via respiratory chain complex abnormal expression and fusion elevation in mice.
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA(2) phosphorylation in experimental ischemic stroke.
Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.
Magnetic Susceptibility Difference-Induced Nucleus Positioning in Gradient Ultrahigh Magnetic Field.
Bruceine D induces lung cancer cell apoptosis and autophagy via the ROS/MAPK signaling pathway in vitro and in vivo.
trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop.
Parkin and Nrf2 prevent oxidative stress-induced apoptosis in intervertebral endplate chondrocytes via inducing mitophagy and anti-oxidant defenses.
Flavonoids extracted from mulberry (Morus alba L.) leaf improve skeletal muscle mitochondrial function by activating AMPK in type 2 diabetes.
Silibinin ameliorats H(2)O(2)-induced cell apoptosis and oxidative stress response by activating Nrf2 signaling in trophoblast cells.
Brain-Specific Serine-47 Modification of Cytochrome c Regulates Cytochrome c Oxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling.
16-Hydroxycleroda-3,13-dien-15,16-olide Induces Apoptosis in Human Bladder Cancer Cells through Cell Cycle Arrest, Mitochondria ROS Overproduction, and Inactivation of EGFR-Related Signalling Pathways.
Transplantation of platelet-derived mitochondria alleviates cognitive impairment and mitochondrial dysfunction in db/db mice.
Antagomirs targeting miR-142-5p attenuate pilocarpine-induced status epilepticus in mice.
Deregulated MTOR (mechanistic target of rapamycin kinase) is responsible for autophagy defects exacerbating kidney stone development.
Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells.
Lanthanum chloride impairs spatial learning and memory by inducing [Ca(2+)](m) overload, mitochondrial fission-fusion disorder and excessive mitophagy in hippocampal nerve cells of rats.
A novel STAT3 inhibitor, HJC0152, exerts potent antitumor activity in glioblastoma.
Mitochondrial DNA 3,860-bp Deletion Increases with Aging in the Auditory Nervous System of C57BL/6J Mice.
Modulations of Histone Deacetylase 2 Offer a Protective Effect through the Mitochondrial Apoptosis Pathway in Acute Liver Failure.
Determination of the Molecular Mechanism of Torularhodin against Hepatic Oxidative Damage by Transcriptome Analysis.
NADPH Oxidase 2-Mediated Insult in the Auditory Cortex of Zucker Diabetic Fatty Rats.
Upregulation of UCP2 Expression Protects against LPS-Induced Oxidative Stress and Apoptosis in Cardiomyocytes.
Fetal bovine serum inhibits neomycin-induced apoptosis of hair cell-like HEI-OC-1 cells by maintaining mitochondrial function.
SIRT5 Promotes Hepatocellular Carcinoma Progression by Regulating Mitochondrial Apoptosis.
NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly.
Bone marrow adipose tissue-derived stem cell factor mediates metabolic regulation of hematopoiesis.
Mitochondria-Targeting Thermosensitive Initiator with Enhanced Anticancer Efficiency.
GCN5L1 controls renal lipotoxicity through regulating acetylation of fatty acid oxidation enzymes.
Deficiency of mitophagy receptor FUNDC1 impairs mitochondrial quality and aggravates dietary-induced obesity and metabolic syndrome.
Viral Nonstructural Protein 1 Induces Mitochondrion-Mediated Apoptosis in Mink Enteritis Virus Infection.
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.
Benzoylaconine induces mitochondrial biogenesis in mice via activating AMPK signaling cascade.
Mutations in the MRPS28 gene encoding the small mitoribosomal subunit protein bS1m in a patient with intrauterine growth retardation, craniofacial dysmorphism and multisystemic involvement.
NADPH oxidase inhibitor apocynin decreases mitochondrial dysfunction and apoptosis in the ventral cochlear nucleus of D-galactose-induced aging model in rats.
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.
Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.
2-D08 as a SUMOylation inhibitor induced ROS accumulation mediates apoptosis of acute myeloid leukemia cells possibly through the deSUMOylation of NOX2.
Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy.
Phosphorylation of MAVS/VISA by Nemo-like kinase (NLK) for degradation regulates the antiviral innate immune response.
Phenylephrine Alleviates (131)I Radiation Damage in Submandibular Gland Through Maintaining Mitochondrial Homeostasis.
Effects of resveratrol on regulation on UCP2 and cardiac function in diabetic rats.
Brain microvascular endothelial cell exosome-mediated S100A16 up-regulation confers small-cell lung cancer cell survival in brain.
NDUFAB1 protects against obesity and insulin resistance by enhancing mitochondrial metabolism.
Mitochondrial respiratory chain dysfunction mediated by ROS is a primary point of fluoride-induced damage in Hepa1-6 cells.
Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum.
Liraglutide ameliorates non-alcoholic steatohepatitis by inhibiting NLRP3 inflammasome and pyroptosis activation via mitophagy.
Promotion of Mitochondrial Biogenesis via Activation of AMPK-PGC1ɑ Signaling Pathway by Ginger (Zingiber officinale Roscoe) Extract, and Its Major Active Component 6-Gingerol.
EIF4G1 is a novel candidate gene associated with severe asthenozoospermia.
Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes.
MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1.
Zinc accumulation in mitochondria promotes ischemia-induced BBB disruption through Drp1-dependent mitochondria fission.
Increased Dynamin-Related Protein 1-Dependent Mitochondrial Fission Contributes to High-Fat-Diet-Induced Cardiac Dysfunction and Insulin Resistance by Elevating Tafazzin in Mouse Hearts.
O-GlcNAcylation on Rab3A attenuates its effects on mitochondrial oxidative phosphorylation and metastasis in hepatocellular carcinoma.
SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice.
A high-fat diet impairs mitochondrial biogenesis, mitochondrial dynamics, and the respiratory chain complex in rat myocardial tissues.
Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance.
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element-modifying factor 1.
Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity.
Modulation of sphingosine 1-phosphate (S1P) attenuates spatial learning and memory impairments in the valproic acid rat model of autism.
Hyper-acetylation contributes to the sensitivity of chemo-resistant prostate cancer cells to histone deacetylase inhibitor Trichostatin A.
Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.
NF-κB and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis.
Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway.
Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions.
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
Inhibition of mitochondrial translation in fibroblasts from a patient expressing the KARS p.(Pro228Leu) variant and presenting with sensorineural deafness, developmental delay, and lactic acidosis.
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway.
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
Curcumin inhibits the growth of liver cancer stem cells through the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway.
The dual role of poly(ADP-ribose) polymerase-1 in modulating parthanatos and autophagy under oxidative stress in rat cochlear marginal cells of the stria vascularis.
The cellular stress proteins CHCHD10 and MNRR1 (CHCHD2): Partners in mitochondrial and nuclear function and dysfunction.
Propofol Through Upregulating Caveolin-3 Attenuates Post-Hypoxic Mitochondrial Damage and Cell Death in H9C2 Cardiomyocytes During Hyperglycemia.
Fish oil feeding reverses hepatomegaly and disrupted hepatic function due to the lack of FXR signaling.
Inhibition of Caveolae Contributes to Propofol Preconditioning-Suppressed Microvesicles Release and Cell Injury by Hypoxia-Reoxygenation.
A unique polysaccharide purified from Hericium erinaceus mycelium prevents oxidative stress induced by H2O2 in human gastric mucosa epithelium cell.
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome.
Docosahexaenoic acid increases the expression of oxidative stress-induced growth inhibitor 1 through the PI3K/Akt/Nrf2 signaling pathway in breast cancer cells.
Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts.
Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.
Impaired mitochondrial fusion, autophagy, biogenesis and dysregulated lipid metabolism is associated with preeclampsia.
PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
MICU1 Alleviates Diabetic Cardiomyopathy Through Mitochondrial Ca(2+)-Dependent Antioxidant Response.
The changes in glucose metabolism and cell proliferation in the kidneys of polycystic kidney disease mini-pig models.
CSFV induced mitochondrial fission and mitophagy to inhibit apoptosis.
Polyphyllin I induces G2/M phase arrest and apoptosis in U251 human glioma cells via mitochondrial dysfunction and the JNK signaling pathway.
Mitochondria-Associated Apoptosis in Human Melanoma Cells Induced by Cardanol Monoene from Cashew Nut Shell Liquid.
Low-level laser therapy for beta amyloid toxicity in rat hippocampus.
ABT737 induces mitochondrial pathway apoptosis and mitophagy by regulating DRP1-dependent mitochondrial fission in human ovarian cancer cells.
Deficiency of PHB complex impairs respiratory supercomplex formation and activates mitochondrial flashes.
CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.
Vitamin K2 Induces Mitochondria-Related Apoptosis in Human Bladder Cancer Cells via ROS and JNK/p38 MAPK Signal Pathways.
Mir143-BBC3 cascade reduces microglial survival via interplay between apoptosis and autophagy: Implications for methamphetamine-mediated neurotoxicity.
Oral quercetin administration transiently protects respiratory function in dystrophin-deficient mice.
ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy.
Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway.
Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice.
Identification of a novel mitochondrial interacting protein of C1QBP using subcellular fractionation coupled with CoIP-MS.
HDAC4 mediates IFN-γ induced disruption of energy expenditure-related gene expression by repressing SIRT1 transcription in skeletal muscle cells.
Liraglutide suppresses obesity and induces brown fat-like phenotype via Soluble Guanylyl Cyclase mediated pathway in vivo and in vitro.
Pseudolaric acid B induces mitotic arrest and apoptosis in both 5-fluorouracil-sensitive and -resistant colorectal cancer cells.
Exercise Inducible Lactate Dehydrogenase B Regulates Mitochondrial Function in Skeletal Muscle.
Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients.
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
PCSK9 regulates apoptosis in human neuroglioma u251 cells via mitochondrial signaling pathways.
8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition.
FUS Interacts with HSP60 to Promote Mitochondrial Damage.
Development of a mitochondria-based centrifugal ultrafiltration/liquid chromatography/mass spectrometry method for screening mitochondria-targeted bioactive constituents from complex matrixes: Herbal medicines as a case study.
Reduction of zinc accumulation in mitochondria contributes to decreased cerebral ischemic injury by normobaric hyperoxia treatment in an experimental stroke model.
Bcl-2 phosphorylation triggers autophagy switch and reduces mitochondrial damage in limb remote ischemic conditioned rats after ischemic stroke.
Furazolidone induces apoptosis through activating reactive oxygen species-dependent mitochondrial signaling pathway and suppressing PI3K/Akt signaling pathway in HepG2 cells.
RIP1-dependent Bid cleavage mediates TNFα-induced but Caspase-3-independent cell death in L929 fibroblastoma cells.
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Trichostatin A targets the mitochondrial respiratory chain, increasing mitochondrial reactive oxygen species production to trigger apoptosis in human breast cancer cells.
Treatment with carnosine reduces hypoxia-ischemia brain damage in a neonatal rat model.
N -methyl- N -nitrosourea-induced retinal degeneration in mice.
S1 kills MCF-7/ADR cells more than MCF-7 cells: A protective mechanism of endoplasmic reticulum stress.
Phosphorylation of p38 MAPK mediates hypoxic preconditioning-induced neuroprotection against cerebral ischemic injury via mitochondria translocation of Bcl-xL in mice.
Mitochondrial bioenergetic deficits in the hippocampi of rats with chronic ischemia-induced vascular dementia.
alpha-Bisabolol induces dose- and time-dependent apoptosis in HepG2 cells via a Fas- and mitochondrial-related pathway, involves p53 and NFkappaB.
Yang Y, Zhou H, Yang J, Li F, Hu Q, Jia Y, Huang W, Qin L, Zhou Y
Journal of inflammation research 2026;19:540176
Journal of inflammation research 2026;19:540176
The YY1-KIF15-PRDX1 axis promotes gastric cancer progression by inducing mitochondrial ROS imbalance.
Li W, Wu B, Qian H, Zhang G, Wang X, Li X
Oncogene 2026 May;45(16):1437-1452
Oncogene 2026 May;45(16):1437-1452
Curcumin augments mitophagy via Nrf2-PINK1-mediated, Parkin-dependent ubiquitination to suppress ferroptosis in post-cardiac arrest brain injury.
Li Z, Xu W, Ren S, Zheng Q, Xing J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158035
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158035
Osteoblast-derived osteomodulin restrains osteoclastogenesis via ITGB8/RRM2-mediated reduction of mitochondrial respiration and mitochondrial ATP production.
Jiang X, Chen H, Hou W, Dai C, Zhang R, Chen E, Zhang J, Wu W, Xu J, Chen M, Liu L, Tan X, Ji X, Wu X, Wang K, Yu C, Yu X, Li W, Zhang W
Experimental & molecular medicine 2026 Mar;58(3):879-897
Experimental & molecular medicine 2026 Mar;58(3):879-897
BNIP3L-Mediated Mitophagy Inhibits Cadmium-Induced Apoptosis in the Rat Cerebral Cortex.
Wang L, Zhang Q, Hou Y, Miao W, Wen S
Journal of biochemical and molecular toxicology 2026 Mar;40(3):e70747
Journal of biochemical and molecular toxicology 2026 Mar;40(3):e70747
NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2.
Zhang L, Zhang Y, Wen D, Guo S, Qi X, Wang H, Sun Y, Yang G, Wang Y, Xue S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e05240
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e05240
Complement 5a receptor 2 attenuates diabetic kidney disease by promoting mitochondria-associated endoplasmic reticulum membrane formation mediated by PSS-MFN2 interaction.
Zhao YY, Wang YH, Li ZH, Chang DY, Nie L, Zhao MH, Tang SCW, Chen M
Cell discovery 2026 Mar 31;12(1)
Cell discovery 2026 Mar 31;12(1)
NAD+ subcellular partitioning mediated by miR-183 and miR-96 regulates muscle stem cell differentiation.
Ma M, Ma R, Li Z, Shen S, Kong W, Qiu T, Niu Z, Chen J, Wu Y, Li Y, Jin ZB, Li Y, Ying H
Journal of molecular cell biology 2026 Mar 31;
Journal of molecular cell biology 2026 Mar 31;
S100A11 regulates microglial inflammatory response in neuropathic pain via H3K27ac-TFEB-mitochondrial autophagy axis.
Zheng H, Tian S, Wu L, Jia G, Xiao Y, Yu X, Zuo Q, Zhou R, Min J, Wu Q, Xie H, Luo Q, Wu W
The journal of headache and pain 2026 Mar 11;27(1)
The journal of headache and pain 2026 Mar 11;27(1)
Qiang-Xin 1 formula improves cardiac function and alleviates myocardial injury in lipopolysaccharide-induced septic mice by activating calcium/calmodulin-dependent protein kinase I-mediated mitophagy.
Huang P, Wang Q, Zhu Y, Hu X, Fang X, Deng W, Cao P, He S
Journal of ethnopharmacology 2026 Mar 1;358:121033
Journal of ethnopharmacology 2026 Mar 1;358:121033
Paeoniflorin mitigates myocardial hypertrophy by regulating mitophagy and ferroptosis mediated by mitochondria-associated AMPK-Parkin-ACSL4 pathway.
Wang Y, Lin S, Liu J, Hu S, Zeng J, Wang M, Li X, He Y, Ren S, Lyu Y, Jia W, Zhao Y, Lin Y
Free radical biology & medicine 2026 Mar 1;245:98-114
Free radical biology & medicine 2026 Mar 1;245:98-114
Echinacoside modulates PARP14-GLUD1 axis to mediate energy metabolism reprogramming and mitochondrial function in diminished ovarian reserve.
Liang H, Shu C, Huang Z, Yuan S, Yang Q, Chen S, Zhou X, Yang N, Xiang X, Xia Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158100
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158100
COX17 Attenuates Diabetes-Associated Retinal Injury by Improving Mitochondrial Function.
Lian HY, Deng ZD, Yan M, Huang Z, Ye Y, Song YP
Clinical and experimental pharmacology & physiology 2026 Jan;53(1):e70098
Clinical and experimental pharmacology & physiology 2026 Jan;53(1):e70098
Hyperuricemia exacerbates acetaminophen hepatotoxicity via JNK activation and mitophagy reduction.
Liu Y, Peng B, Li D, Chen J, Lai Y, You Y, Jiang Z, Zhou X, Wu C, Chen L, Kwan HY, Yu L, Zuo D, Zhao X
Biochemical pharmacology 2026 Jan;243(Pt 1):117487
Biochemical pharmacology 2026 Jan;243(Pt 1):117487
Sphinganine-induced lysosomal membrane permeabilization: Interplay with subcellular oxidative levels.
Cheng G, Qi C, Xu H, Wang X, Li M, Chen H, Zheng P, Liu Y, Liu J, Zhao X
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Jan;1871(1):159705
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Jan;1871(1):159705
Targeting PAK4 promotes Gemcitabine-induced pyroptosis in pancreatic cancer via NLRP1/caspase-3/GSDME axis.
Lu T, Song Y, Liang K, Zhang Z, Li Y, Tan X, Li X, Li F
Communications biology 2026 Jan 16;9(1):260
Communications biology 2026 Jan 16;9(1):260
BNIP3-mediated mitophagy alleviates traumatic brain injury by inhibiting neuronal apoptosis and oxidative stress.
Yin H, Wei Y, Han Z, Li Z, Liu K, Zhu L
International immunopharmacology 2026 Jan 1;168(Pt 1):115793
International immunopharmacology 2026 Jan 1;168(Pt 1):115793
Mechano-matching hydrogel patch promotes myocardial infarction repair via YAP-Bcl-2 pathway activation.
Zhao Y, Shen J, Lin R, Huang J, Zou X, Hou H, Qiu X
Materials today. Bio 2026 Feb;36:102670
Materials today. Bio 2026 Feb;36:102670
p62/SQSTM1 Condensation Modulates Mitochondrial Clustering to Participate in Mitochondrial Quality Control.
Sun S, Xin J, Zhang Y, Yang B, Su D, Ni R, Ma Q, Li N, Ma G, Peng Q, Chen S, Prehn JHM, Tam KY, Wang H, Ying Z
Aging cell 2026 Feb;25(2):e70402
Aging cell 2026 Feb;25(2):e70402
A Novel CYP2E1 Inhibitor, 4-Methyl-5-Acetylthiazole (Q11), Alleviates Obesity Via Modulating Adipose Inflammation and Mitochondrial Dysfunction.
Qiu J, Gao L, Wang L, Wang X, Jia L, Deng M, Tang L, Wen Q, Gao N, Xu H, Qiao H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e15315
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e15315
Ginsenoside Rg5 Targets PRDX1 to Disrupt Redox Homeostasis and Induce Mitochondria-Dependent Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells.
Ye HL, Wang YN, Li GA, Jin XH, Wu GT, Li Y, Jin YH
Molecules (Basel, Switzerland) 2026 Feb 5;31(3)
Molecules (Basel, Switzerland) 2026 Feb 5;31(3)
Discovery of α-carboline fused benzofuran-containing anticancer agents as rapid apoptosis inducers through intrinsic pathway.
Lin F, Luo Z, Wu Q, Lv L, Chen Z, He Y, Yuan HX, Zhao Y, Nie S
European journal of medicinal chemistry 2026 Feb 5;303:118464
European journal of medicinal chemistry 2026 Feb 5;303:118464
PM(10) Disrupts Mitochondrial Homeostasis in Corneal Epithelial Cells: Protective Effects of SKQ1.
Somayajulu M, Wright R, Muhammed FS, McClellan SA, Ibrahim AS, Hazlett LD
Antioxidants (Basel, Switzerland) 2026 Feb 25;15(3)
Antioxidants (Basel, Switzerland) 2026 Feb 25;15(3)
Novel mechanism of neuronal hypoxia response: HIF-1α/STOML2 mediated PINK1-dependent mitophagy activation against neuronal injury.
Li Y, Xu Z, Tian Z, Guo M, Shao Q, Liu Y, Gu Y, Jin F, Ji X, Liu J
Cell death discovery 2026 Feb 21;12(1)
Cell death discovery 2026 Feb 21;12(1)
Integrative Proteomic and Bioenergetic Profiling Reveals Diet- and Strain-Specific Mitochondrial Dysfunction in Cohen Diabetic Rat Hearts.
Pavelich L, Arroum T, Pham L, Komnenov D, Stemmer PM, Lax R, Saada A, Weksler-Zangen S, Hüttemann M
Antioxidants (Basel, Switzerland) 2026 Feb 13;15(2)
Antioxidants (Basel, Switzerland) 2026 Feb 13;15(2)
Mast Cell Chymase and Human Lung Fibroblast Interaction: Mechanisms and Implications for Asthma.
Pejler G, Paivandy A, Rabelo Melo F, Allam VSRR, Öberg A, Wen Q, Bergsten P, Zhao XO
Inflammation 2026 Feb 10;49(1)
Inflammation 2026 Feb 10;49(1)
FABP4 is highly expressed in preeclamptic placentas and regulates trophoblast lipid metabolism, mitochondrial function, and oxidative stress in vitro.
Sun H, Wang Q, Wu L, Jing R, Xuan S, Zhuang W
BMC pregnancy and childbirth 2026 Feb 10;26(1)
BMC pregnancy and childbirth 2026 Feb 10;26(1)
Urolithin A alleviates vascular remodeling through mitochondrial SIRT3-mediated SOD2 deacetylation and antioxidation in hypertensive rats.
Dai M, Wang YM, Dong HK, Xu XY, Wang JX, Zhu GQ, Zheng F
Redox report : communications in free radical research 2026 Dec;31(1):2622255
Redox report : communications in free radical research 2026 Dec;31(1):2622255
Renal-targeted tFNA-TPP nanoagonist treats acute kidney injury by amplifying mitophagy.
Xu J, Li Y, Xu J, He R, Jiang F, Lu J, Xu T, Wang J, Zhang C
Materials today. Bio 2026 Apr;37:102926
Materials today. Bio 2026 Apr;37:102926
Zinc Overload in Microvessels Contributes to Blood-Brain Barrier Disruption by Activating the JAK2 Pathway After Cerebral Ischemia/Reperfusion.
Guo Z, Shi W, Chen X, Yuan S, Ji X, Qi Z
CNS neuroscience & therapeutics 2026 Apr;32(4):e70885
CNS neuroscience & therapeutics 2026 Apr;32(4):e70885
Celastrol triggers CAV-1-mediated mitochondrion cholesterol metabolism and mitophagy to suppress liver cancer.
Li HF, Zhang CJ, Shi YN, Zhu N, Yang Q, Long JP, Liang YT, Qin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157989
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157989
A tumor-derived mitochondrial tsRNA drives vascular invasion of lung adenocarcinoma by promoting ribosomal assembly in endothelial cells.
Liang S, Wang Q, Zhang M, Song X, Zhang Y, Wang H, Feng Y, Li R, Xia W, Xu L, Dong G, Mao Q, Jiang F
Cancer letters 2026 Apr 28;644:218324
Cancer letters 2026 Apr 28;644:218324
Small-molecule binding-site discovery using silyl ether-enabled chemoproteomics.
Ngo C, Takechi S, Sivakumar A, Villanueva M, Yu F, Ball AB, Rubio J, Biletch E, Burton NR, Boatner LM, Kim P, Turmon AC, Perumal N, Liesa M, Divakaruni AS, Nesvizhskii AI, Backus KM
Nature chemistry 2026 Apr 27;
Nature chemistry 2026 Apr 27;
Translocator protein in touch with mitochondrial chloride intracellular channel CLIC5.
Dekhtiarenko R, Polcicova K, Tomaskova ZS
Biochemical and biophysical research communications 2026 Apr 23;810:153537
Biochemical and biophysical research communications 2026 Apr 23;810:153537
Enterovirus A71 3AB protein facilitates immune evasion by blocking cGAS recognition of mtDNA.
Sun P, Yang X, Cui J, Fang G, Wu Y, Chang J, Li X, Xie Y, Gan L, Ma L, Li Z
EMBO reports 2026 Apr 2;
EMBO reports 2026 Apr 2;
Autophagy cargo profiles in skeletal muscle during starvation and exercise.
Farhan M, Lyu S, Nguyen TP, Zhang D, Liang H, Zhou Y, An YA, Wang J, Yang H, Du G, Liu Y
Autophagy reports 2025;4(1):2593060
Autophagy reports 2025;4(1):2593060
Role of VDAC1 in hepatocyte apoptosis during acute liver injury in rats induced by obstructive jaundice.
Liu J, Hu J, Xu H, Yan L, Yao J, Cao B
Iranian journal of basic medical sciences 2025;28(1):87-97
Iranian journal of basic medical sciences 2025;28(1):87-97
A method for isolating and cryopreserving intact mitochondria with improved integrity and functionality.
Okutani A, Naima J, Ogihara A, Motoichi T, Ohsawa I, Ohta Y
Biophysics and physicobiology 2025;22(2):e220012
Biophysics and physicobiology 2025;22(2):e220012
Metformin Alleviates Liver Metabolic Dysfunction in Polycystic Ovary Syndrome by Activating the Ethe1/Keap1/PINK1 Pathway.
Xie Y, Tian Y, Huang J, Deng W, Li X, Liu Y, Liu H, Gao L, Xie Q, Yu Q
International journal of biological sciences 2025;21(8):3505-3526
International journal of biological sciences 2025;21(8):3505-3526
Ganglioside GA2-mediated caspase-11 activation drives macrophage pyroptosis aggravating intimal hyperplasia after arterial injury.
Shi Y, He T, Liu H, Li X, Li Z, Wen Q, Dai Z, Sun X, Tan Q, Yang W, Jiang Y, Liu Y, Yuan H, Lei F, Yi Y, Cai J
International journal of biological sciences 2025;21(1):433-453
International journal of biological sciences 2025;21(1):433-453
Voluntarily wheel running protects doxorubicin-induced kidney injury by inhibiting oxidative stress through mitochondrial function.
Jiang X, Wang Z, Wang L, Wang Y, Zhao L, Jiang H
PloS one 2025;20(4):e0321121
PloS one 2025;20(4):e0321121
Low-dose radiation ameliorates doxorubicin-induced renal injury via reducing oxidative stress and protecting mitochondrial function.
Chen M, He K, Wang K, Cai Y, Ying Z, Li X, Liu Y, Xiang L, Yang P, Wu H, Jiang J
PloS one 2025;20(2):e0313649
PloS one 2025;20(2):e0313649
TRAP1 Improves Diabetic Retinopathy by Preserving Mitochondrial Function.
Li Y, Xu W, Zhao G, Guo Y, Wang L, Du Q, Fei Y, Hu X, Hu H, Chen L, Xu Y
Clinical ophthalmology (Auckland, N.Z.) 2025;19:2343-2362
Clinical ophthalmology (Auckland, N.Z.) 2025;19:2343-2362
MK-4 Ameliorates Diabetic Osteoporosis in Angiogenesis-Dependent Bone Formation by Promoting Mitophagy in Endothelial Cells.
Ding F, Zhang W, Liu T, Rong X, Cui Y, Meng L, Wang L, Liu B, Li M
Drug design, development and therapy 2025;19:2173-2188
Drug design, development and therapy 2025;19:2173-2188
Calcium dysregulation disrupts mitochondrial homeostasis by interfering AMPK/Drp1 pathway to aggravate plaque progression and instability.
Hu P, Liu M, Wu T, Zhang Y, Liu C, Wang L, Zhang W, Que Y, You J, Yu W, Tong X
Theranostics 2025;15(15):7567-7583
Theranostics 2025;15(15):7567-7583
Detyrosinated α-tubulin mediates mitochondrial dysfunction and diastolic impairment in heart failure with preserved ejection fraction.
Miura S, Misaka T, Sekine T, Ogawara R, Ichimura S, Tomita Y, Yokokawa T, Oikawa M, Ishida T, Takeishi Y
FEBS letters 2025 Sep;599(17):2474-2490
FEBS letters 2025 Sep;599(17):2474-2490
RFX2-BNIP3 axis-driven adaptive mitophagy promotes resistance to ACK1-targeted therapy in non-small cell lung cancer.
Cao K, Wei S, Ma T, Zou X, Meng H, Yang X, Lu M, Wang Y, He X, Ma J, Zhu J
Oncogene 2025 Sep;44(37):3461-3475
Oncogene 2025 Sep;44(37):3461-3475
Oxidative stress-induced decreased expression of FABP5 leads to mitochondrial damage and survival disorder of decidual stromal cells in women with recurrent spontaneous abortion.
Li D, Duan H, Jiang Z, Zhou C, Cao C, Ni M, He L, Zhu X, Jin L, Liu W, Gu L, Li H, Liu D, Zhao X, Zhao G, Li J
Free radical biology & medicine 2025 Sep;237:270-284
Free radical biology & medicine 2025 Sep;237:270-284
METTL14 promotes TBK1 mRNA stability through IGF2BP3-recognized m6A modification and enhances mitophagy in BMSCs.
Shen Y, Wang L, Guo Z, Wang J, Zhang R, Tang C, Wu J
Cellular signalling 2025 Sep;133:111873
Cellular signalling 2025 Sep;133:111873
Prepubertal Diabetes Stagnates Testicular Development by Skewing Autophagy Homeostasis in Leydig Cells.
Tang Z, Zheng Y
Cells 2025 Sep 4;14(17)
Cells 2025 Sep 4;14(17)
HMGA2/PHGDH axis-mediated glycolysis under hypoxia is required for cadmium-induced A549 cell migration.
Gao C, Xie Q, Li L, Luo S, Fan J, Cao J
Ecotoxicology and environmental safety 2025 Sep 15;303:118787
Ecotoxicology and environmental safety 2025 Sep 15;303:118787
Galectin-3 gene deletion alters lipid profile in healthy and cardiomyopathy mouse hearts.
Du XJ, Huynh K, Ziemann M, She G, Wu W, Duong T, Hai XX, Yang YY, Zhao WB, Lu Q, Zhang Y, Deng XL, Meikle PJ
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159676
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159676
TRAP1 inhibits KANSL3 acetylation to alleviate mitochondrial dysfunction by promoting mitophagy in cardiomyocytes under diabetic conditions.
Zhang X, Cheng S, Li W, Xu X, Huang X, Chen Z, Li Q, Huang W, Zhang L, Ouyang M
Cell communication and signaling : CCS 2025 Oct 2;23(1):414
Cell communication and signaling : CCS 2025 Oct 2;23(1):414
Identification of diagnostic biomarkers and mitochondrial metabolic characteristics in sepsis-associated acute kidney injury.
Xia Y, Qian Y, Hu G, Pu Y, Guo J
European journal of medical research 2025 Oct 17;30(1):991
European journal of medical research 2025 Oct 17;30(1):991
PTEN-L dephosphorylates Parkin and Ub Ser65 to aggravate mitophagy dysfunction in prion disease cell models.
Li X, Li J, Gou F, Dai Y, Zhao M, Wang D, Sun Z, Wen P, Wang J, Fan Q, Ma T, Wang X, Zhao D, Yang L
Life sciences 2025 Oct 15;379:123860
Life sciences 2025 Oct 15;379:123860
Bioenergetics of cancer cells: insights into the Warburg effect and regulation of ATP synthase.
Del Dotto V, Grillini S, Righetti R, Grandi M, Giorgio V, Solaini G, Baracca A
Molecular medicine (Cambridge, Mass.) 2025 Oct 13;31(1):311
Molecular medicine (Cambridge, Mass.) 2025 Oct 13;31(1):311
The ubiquitin-binding protein ANKRD13A mediates VCP-dependent mitochondrial outer membrane rupture during PINK1/Parkin-mediated mitophagy.
Chu WH, Lin YS, Guo J, Jane WN, Wang WJ, Lin YY, Liu PH, Huang PY, Chiang WC
The Journal of biological chemistry 2025 Nov;301(11):110739
The Journal of biological chemistry 2025 Nov;301(11):110739
Targeting LARP1 to mitigate aging in lens epithelial cells: mechanistic insights into mitochondrial dysfunction.
Qi H, Sun L, Chai J, Ma J, Yu H, Xia M, Hu X
Experimental eye research 2025 Nov;260:110582
Experimental eye research 2025 Nov;260:110582
Kindlin-1 promotes mitophagy by inhibiting PINK1 degradation to enhance hepatocellular carcinoma progression and modulates sensitivity to donafenib.
Ma H, Ou G, Wu B, Ding H, Zhang Y, Xia F, Shen Z, Zhao K, Chen C, Wu L, Lei J, Xu Y, Zhao X, Cao K, Li H
Cellular signalling 2025 Nov;135:112032
Cellular signalling 2025 Nov;135:112032
Galectin-3 directs mitophagy in response to Parkin-/proteasome-dependent rupture of mitochondrial outer membrane.
Liu PH, Lin YS, Chu WH, Sun WT, Huang PY, Huang JR, Chiang WC
Biology direct 2025 Nov 6;20(1):108
Biology direct 2025 Nov 6;20(1):108
Elucidation of puberulic acid-induced nephrotoxicity using stem cell-based kidney organoids.
Nakanoh H, Tsuji K, Uchida N, Fukushima K, Haraguchi S, Kitamura S, Wada J
Scientific reports 2025 Nov 26;15(1):42195
Scientific reports 2025 Nov 26;15(1):42195
Kaempferol attenuated LPS-induced microglial neurotoxicity by promoting mitophagy to inhibit mtDNA-mediated NLRP3 inflammasome activation.
Xiao L, Liang L, Zhou S, Peng F, Yuan C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157486
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157486
Xingnao jianshen prescription reduces mitochondrial cristae breakage by protecting GPX1 from oxidation against cerebral ischemia-reperfusion injury.
Wang X, Tao K, Sun L, Ren D, Xie S, Zhang K, Li X, Zhao D, Yang Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157369
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157369
Human OPN-derived peptide SV prevents BPD model through interacting with KIF5B to repair mitochondrial damage and inhibit apoptosis.
Yan R, Zhang H, Zhang P, Lv M, Pu Y, Yu L, Jin W, Zhang L, Zhou Y
iScience 2025 Nov 21;28(11):113691
iScience 2025 Nov 21;28(11):113691
Ginsenoside Rh2 as a novel PIN1 inhibitor disrupting the cancer stem cell-like phenotype in non-small cell lung cancer.
Liu X, Mao Z, Yang J, Zhu Q, Dong X, Huang G, Shen X, Zhang L, Yang H
Journal of translational medicine 2025 Nov 10;23(1):1256
Journal of translational medicine 2025 Nov 10;23(1):1256
Dental pulp stem cells alleviate Schwann cell pyroptosis via mitochondrial transfer to enhance facial nerve regeneration.
Zheng X, Wang J, Zhou H, Chai Y, Li Z, Chen M, Yang Z, Xu C, Lei C, He Y, Zou D, Ye Q
Bioactive materials 2025 May;47:313-326
Bioactive materials 2025 May;47:313-326
Daidzein Attenuates Cadmium-Induced Neurotoxicity via Inhibiting Apoptosis and Mitophagy in the Cerebral Cortex of Sprague-Dawley Rats.
Wen S, Zhao Y, Wang L, Yuan Y
Journal of biochemical and molecular toxicology 2025 May;39(5):e70299
Journal of biochemical and molecular toxicology 2025 May;39(5):e70299
Syntaxin 17 Translocation Mediated Mitophagy Switching Drives Hyperglycemia-Induced Vascular Injury.
Luo A, Wang R, Gong J, Wang S, Yun C, Chen Z, Jiang Y, Liu X, Dai H, Liu H, Zheng Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2414960
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(19):e2414960
Mitochondrial Genome-Encoded lncND5 Regulates Mitophagy in Hypoxic Pulmonary Artery Smooth Muscle Cell.
Bai J, He S, Wang X, Zhang L, Ma C, Gao D, Yuan H, Mei J, Guan X, Yu H, Wan K, Zhu D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70618
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70618
Overexpression of c-Myc triggers p62 aggregation-mediated mitochondrial mitophagy in cabozantinib resistance of hepatocellular carcinoma.
Yang K, Zhang X, Yang K, Liu S, Zhang J, Fu Y, Liu T, Wu K, Li J, Liu C, Huang Q, Qu K
Molecular medicine (Cambridge, Mass.) 2025 May 27;31(1):209
Molecular medicine (Cambridge, Mass.) 2025 May 27;31(1):209
Targeting mitochondrial complex I of CD177(+) neutrophils alleviates lung ischemia-reperfusion injury.
Wu J, Gao P, Yang C, Zhuang F, Luo Y, Wen F, Zhang P, Wang L, Xie H, Dai C, Zhao D, Li C, Deng H, Deng Z, Chen C
Cell reports. Medicine 2025 May 20;6(5):102140
Cell reports. Medicine 2025 May 20;6(5):102140
USP14 inhibits mitophagy and promotes tumorigenesis and chemosensitivity through deubiquitinating BAG4 in microsatellite instability-high colorectal cancer.
Wang Z, Yu C, Xie G, Tao K, Yin Z, Lv Q
Molecular medicine (Cambridge, Mass.) 2025 May 2;31(1):163
Molecular medicine (Cambridge, Mass.) 2025 May 2;31(1):163
Retroviral foamy virus gag induces parkin-dependent mitophagy.
Wang S, Du T, Yan J, Zheng Y, Tang Y, Wu J, Xu Q, Xu S, Liu L, Chen X, Han S, Yin J, Peng B, He X, Liu W
Retrovirology 2025 May 2;22(1):7
Retrovirology 2025 May 2;22(1):7
Acid-Triggered Cascaded Responsive Supramolecular Peptide Alleviates Myocardial Ischemia‒Reperfusion Injury by Restoring Redox Homeostasis and Protecting Mitochondrial Function.
Liao X, Tang M, Li J, Guo R, Zhong C, Chen X, Zhang X, Mo H, Que D, Yu W, Song X, Li H, Cai Y, Yang P
Advanced healthcare materials 2025 Mar;14(7):e2404319
Advanced healthcare materials 2025 Mar;14(7):e2404319
Novel biallelic TK2 mutations cause mitochondrial DNA depletion syndrome with infantile early-onset lipid storage myopathy.
Li D, Shi Y, Sun H, Yan C, Lin Y
Orphanet journal of rare diseases 2025 Mar 17;20(1):130
Orphanet journal of rare diseases 2025 Mar 17;20(1):130
PNPLA6 regulates retinal homeostasis by choline through phospholipid turnover.
Ono T, Taketomi Y, Higashi T, Sato H, Mochizuki-Ono C, Nagasaki Y, Ueta T, Miyai T, Tokuoka SM, Oda Y, Nishito Y, Ono T, Taya C, Arata S, Watanabe S, Soga T, Hirabayashi T, Aihara M, Murakami M
Nature communications 2025 Mar 13;16(1):2221
Nature communications 2025 Mar 13;16(1):2221
CHCHD2 rescues the mitochondrial dysfunction in iPSC-derived neurons from patient with Mohr-Tranebjaerg syndrome.
Huang Y, Chen Z, Deng W, Jiang Y, Pan Y, Yuan Z, Hu H, Wu Y, Hu Y
Cell death & disease 2025 Mar 12;16(1):173
Cell death & disease 2025 Mar 12;16(1):173
Inner Mitochondrial Membrane Peptidase 2-Like Deletion Aggravates Mitochondrial Apoptosis and Inhibits Autophagy After Hyperglycemia Stroke.
Ma N, Luo X, Wang J, Sun S, Liang R, Zhang Z, Cheng Z, Wang J, Ma Y
Molecular neurobiology 2025 Jun;62(6):6884-6897
Molecular neurobiology 2025 Jun;62(6):6884-6897
Resveratrol Inhibits VDAC1-Mediated Mitochondrial Dysfunction to Mitigate Pathological Progression in Parkinson's Disease Model.
Feng S, Gui J, Qin B, Ye J, Zhao Q, Guo A, Sang M, Sun X
Molecular neurobiology 2025 Jun;62(6):6636-6654
Molecular neurobiology 2025 Jun;62(6):6636-6654
α‑ketoglutarate protects against septic cardiomyopathy by improving mitochondrial mitophagy and fission.
Wu W, Ma Q, Li BT, Shi S, Guan GC, Wang JK, Xue BY, Liu ZW
Molecular medicine reports 2025 Jun;31(6)
Molecular medicine reports 2025 Jun;31(6)
The mitochondrial protease ClpP is a promising target for multiple myeloma treatment.
Liu X, Gu J, Liu S, Huang J, Li L, Wang F, He S, Mi Z, Zhang Y, Wen J, Gao Q, Yang H, Feng Y, Luo H, Zhai X, Zhang L, Zheng Y, Luo Y, Niu T
Biochemical pharmacology 2025 Jun;236:116855
Biochemical pharmacology 2025 Jun;236:116855
PFOS causes lysosomes-regulated mitochondrial fission through TRPML1-VDAC1 and oligomerization of MCU/ATP5J2.
Yang W, Li Y, Feng R, Liang P, Tian K, Hu L, Wang K, Qiu T, Zhang J, Sun X, Yao X
Journal of hazardous materials 2025 Jun 5;489:137685
Journal of hazardous materials 2025 Jun 5;489:137685
STING-mediated mitochondrial DNA release exacerbates PANoptosis in liver ischemia reperfusion injury.
Wu C, Miao H, Yi Z, Jia H, Huang A, Zhang H, Liu Z, Sun X, Zheng Y, Gao L, Ma S
International immunopharmacology 2025 Jun 5;157:114778
International immunopharmacology 2025 Jun 5;157:114778
Pyruvate metabolism enzyme DLAT promotes tumorigenesis by suppressing leucine catabolism.
Wang N, Lu S, Cao Z, Li H, Xu J, Zhou Q, Yin H, Qian Q, Zhang X, Tao M, Jiang Q, Zhou P, Zheng L, Han L, Li H, Yin L, Gu Y, Dou X, Sun H, Wang W, Piao HL, Li F, Xu Y, Yang W, Chen S, Liu J
Cell metabolism 2025 Jun 3;37(6):1381-1399.e9
Cell metabolism 2025 Jun 3;37(6):1381-1399.e9
Antihypertensive Drug Amlodipine Besylate Shows Potential in Alleviating Diabetic Peripheral Neuropathy.
Wei Y, Huang Y, Huang R, Ruan Y, Feng T, Zhou F, Zhang W, Lu J, Xie S, Yao Y, Wang J, Ji S, Shen X
Diabetes 2025 Jun 1;74(6):983-997
Diabetes 2025 Jun 1;74(6):983-997
Corticosterone induces fatty liver syndrome in chickens via glucocorticoid receptor and inhibition of mitochondrial supercomplex formation.
Chen H, Zhang K, Yu H, Guan Z, Zhao R, Wu L
American journal of physiology. Regulatory, integrative and comparative physiology 2025 Jun 1;328(6):R770-R782
American journal of physiology. Regulatory, integrative and comparative physiology 2025 Jun 1;328(6):R770-R782
Homocysteine induced N(6)-methyldeoxyadenosine modification perturbation elicits mitochondria dysfunction contributes to the impairment of learning and memory ability caused by early life stress in rats.
Zhang L, Xie F, Wang X, Sun Z, Wu Y, Sun Z, Zhang S, Chen X, Zhao Y, Qian L
Redox biology 2025 Jul;84:103668
Redox biology 2025 Jul;84:103668
Gut microbiota-bile acid crosstalk contributes to calcium oxalate nephropathy through Hsp90α-mediated ferroptosis.
Liu L, Ma Y, Jian Z, Liao B, Li Y, Lin L, Wang M, Chen J, Wei J, Yang M, Liu Y, Yuan Y, Wen J, Xiang L, Qi S, Jin X, Wang K
Cell reports 2025 Jul 22;44(7):115936
Cell reports 2025 Jul 22;44(7):115936
Harnessing tissue-derived mitochondria-rich extracellular vesicles (Ti-mitoEVs) to boost mitochondrial biogenesis for regenerative medicine.
Lou P, Zhou X, Zhang Y, Xie Y, Wang Y, Wang C, Liu S, Wan M, Lu Y, Liu J
Science advances 2025 Jul 18;11(29):eadt1318
Science advances 2025 Jul 18;11(29):eadt1318
Poldip2 Aggravates inflammation in diabetic retinopathy by impairing mitophagy via the AMPK/ULK1/Pink1 pathway.
Lin S, Ji Z, Gao J, Fan J, Hou J, Liu S, Wang C, Chen K, Tao L, Jiang Z
Life sciences 2025 Jul 15;373:123681
Life sciences 2025 Jul 15;373:123681
Fatty Acid Metabolism via CPT1A Supports Poll Gland Function and Rutting Activities in Male Bactrian Camels.
Ma Q, Zhang B, Zhou B, Zhang Q, Gao Y
Biomolecules 2025 Jul 11;15(7)
Biomolecules 2025 Jul 11;15(7)
Astroglial membrane camouflaged Ptbp1 siRNA delivery hinders glutamate homeostasis via SDH/Nrf2 pathway.
Liu Y, Ren J, Zhang W, Ding L, Ma R, Zhang M, Zheng S, Liang R, Zhang Y
Biomaterials 2025 Jan;312:122707
Biomaterials 2025 Jan;312:122707
Isoliquiritin targeting m5C RNA methylation improves mitophagy in doxorubicin-induced myocardial cardiotoxicity.
Fu J, Cheng L, Zhang J, Sun R, Yu M, Wu M, Li S, Cui X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156293
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156293
Impaired Iron-Sulfur Cluster Synthesis Induces Mitochondrial PARthanatos in Diabetic Cardiomyopathy.
Wang M, Zhang S, Tian J, Yang F, Chen H, Bai S, Kang J, Pang K, Huang J, Dong M, Dong S, Tian Z, Fang S, Fan H, Lu F, Yu B, Li S, Zhang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(1):e2406695
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jan;12(1):e2406695
Ubiquitin specific peptidase 11 knockdown slows Huntington's disease progression via regulating mitochondrial dysfunction and neuronal damage depending on PTEN-mediated AKT pathway.
Gao B, Jing Y, Li X, Cong S
Molecular medicine (Cambridge, Mass.) 2025 Jan 8;31(1):7
Molecular medicine (Cambridge, Mass.) 2025 Jan 8;31(1):7
Aristolochic acid I induced mitochondrial Ca(2+) accumulation triggers the production of MitoROS and activates Src/FAK pathway in hepatocellular carcinoma cells.
Hu Y, Zhang Q, Jiang W, Wang X, Guo X, Chen L, Cheng S, Ying J, Ye J, Zhang L
Chemico-biological interactions 2025 Jan 5;405:111269
Chemico-biological interactions 2025 Jan 5;405:111269
Sirtuin-1 Regulates Mitochondrial Calcium Uptake Through Mitochondrial Calcium Uptake 1 (MICU1).
Zhang X, Liu S, Su Y, Zhang L, Guo T, Wang X
Life (Basel, Switzerland) 2025 Jan 25;15(2)
Life (Basel, Switzerland) 2025 Jan 25;15(2)
Idebenone Protects Photoreceptors Impaired by Oxidative Phosphorylation Disorder in Retinal Detachment.
Wang L, Zou G, Yan Y, Shi R, Guo Y, Zhang M, Lu L, Dong K
Investigative ophthalmology & visual science 2025 Jan 2;66(1):17
Investigative ophthalmology & visual science 2025 Jan 2;66(1):17
OPA3 inhibits the cGAS-STING pathway mediated by mtDNA stress to promote colorectal cancer progression.
Yin Y, Ma Z, Yuan S, Xu K, Wang X
In vitro cellular & developmental biology. Animal 2025 Feb;61(2):165-177
In vitro cellular & developmental biology. Animal 2025 Feb;61(2):165-177
Nonenzymatic lysine D-lactylation induced by glyoxalase II substrate SLG dampens inflammatory immune responses.
Zhao Q, Wang Q, Yao Q, Yang Z, Li W, Cheng X, Wen Y, Chen R, Xu J, Wang X, Qin D, Zhu S, He L, Li N, Wu Y, Yu Y, Cao X, Wang P
Cell research 2025 Feb;35(2):97-116
Cell research 2025 Feb;35(2):97-116
CD24 flags anastasis in melanoma cells.
Vasileva MH, Bennemann A, Zachmann K, Schön MP, Frank J, Ulaganathan VK
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):1-15
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):1-15
Aβ -induced excessive mitochondrial fission drives type H blood vessels injury to aggravate bone loss in APP/PS1 mice with Alzheimer's diseases.
Zhang W, Ding F, Rong X, Ren Q, Hasegawa T, Liu H, Li M
Aging cell 2025 Feb;24(2):e14374
Aging cell 2025 Feb;24(2):e14374
β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy.
Huo Y, Shen T, Feng T, Li M, Zhao W, Loor JJ, Aernouts B, Psifidi A, Xu C
Journal of animal science and biotechnology 2025 Feb 1;16(1):15
Journal of animal science and biotechnology 2025 Feb 1;16(1):15
Zn(2 +) alleviates ischemia/reperfusion injury in H9c2 cells by modulating mitochondrial biogenesis and dynamics via MCU.
Wang B, Xing B, Huang L, Li X, Bian X, Xi J
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Dec;92:127769
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Dec;92:127769
Porphyromonas gingivalis Induces Endothelial Dysfunction Through Sirt3-Dependent CypD Acetylation.
Xu S, Zheng C, Huang J, Lu B, Que H, Xu L, Hou Y, He L, Fan X, Deng K, Hu R, Deng H, Wang Y
Journal of periodontal research 2025 Dec;60(12):1296-1307
Journal of periodontal research 2025 Dec;60(12):1296-1307
Vitexin enhances mitophagy and improves renal ischemia-reperfusion injury by regulating the p38/MAPK pathway.
Chen J, Chen C, Lv C, Feng R, Zhong W, Liu Y, Zhou S, Zhao M
Renal failure 2025 Dec;47(1):2463572
Renal failure 2025 Dec;47(1):2463572
RAB3GAP2 silencing alleviates oxidative stress in cataracts by enhancing Mfn2-mediated mitochondrial autophagy by activating JNK/STAT3.
Huang Y, Liu Q, Chen L, Tan X, Zeng D, Zhang Y, Qin J, Zeng F, Wei X, Zhong Q, Zhang J, Yuan D
International journal of biological macromolecules 2025 Dec;334(Pt 2):149102
International journal of biological macromolecules 2025 Dec;334(Pt 2):149102
Naringenin boosts Parkin-mediated mitophagy via estrogen receptor alpha to maintain mitochondrial quality control and heal diabetic foot ulcer.
Zhou XM, Yang Y, Yu DJ, Xie T, Sun XL, Han YX, Tian HY, Liao QQ, Zhao YJ, Liou YC, Huang W, Xu Y, Kuang X, Sun XD, Zhang YY
Journal of pharmaceutical analysis 2025 Dec;15(12):101333
Journal of pharmaceutical analysis 2025 Dec;15(12):101333
Hispolon reduces mitochondrial dysfunction and improves fibrosis of diabetes nephropathy by activating AMPK signal and inhibiting mPTP opening.
Wang Y, Danis A, Wang X, Ren J, Ma T, Wang R
Cellular signalling 2025 Dec;136:112130
Cellular signalling 2025 Dec;136:112130
Kaempferol exerts anti-colorectal cancer effects through its multi-target mediated glucose metabolism remodeling.
Wu H, Guo Z, Hu P, Du J, Wang P, Ma J, Zhao B, Wei J, Li Z
Food & function 2025 Dec 8;16(24):9593-9608
Food & function 2025 Dec 8;16(24):9593-9608
LRPPRC-Driven Oxidative Phosphorylation Is Associated with Elesclomol-Induced Cuproptosis in Ovarian Cancer.
Wu Y, Zhang W, Jiang S, Liu S, Su J, Sun L
International journal of molecular sciences 2025 Dec 31;27(1)
International journal of molecular sciences 2025 Dec 31;27(1)
Uptake mechanisms and functions of isolated mitochondria in mesenchymal stromal cells.
Kanai M, Goto M, Itakura S, Nishikawa M, Kusamori K
Scientific reports 2025 Dec 29;15(1):44799
Scientific reports 2025 Dec 29;15(1):44799
LncRNA-encoded peptide LRRC75A-AS1-ORF3 suppresses anti-tumor immunity in colorectal cancer through mitophagy-mediated attenuation of cGAS-STING signaling.
Wu Q, Li Z, He X, Yu S, Zhang M, Mo H, He S, Li J, Ni W
Carcinogenesis 2025 Dec 26;47(1)
Carcinogenesis 2025 Dec 26;47(1)
Ginsenoside Rh2 inhibits mesenchymal stem cell senescence by regulating mitochondrial and lysosomal function.
Zhuang J, Li Y, Huang YL, Wang X, Lin NM
Stem cell research & therapy 2025 Dec 24;16(1):683
Stem cell research & therapy 2025 Dec 24;16(1):683
High matrix stiffness triggers the YAP-OPA1-TET1/3 loop to drive chemoresistance via enhanced nuclear-mitochondrial communication.
Wu P, Wang S, Hu Z, Zhang H, Lin Y, Li Z, Wu J, Chen Y, Chen Y, Xu Y, Li J, Guan Y
iScience 2025 Dec 19;28(12):113996
iScience 2025 Dec 19;28(12):113996
Lactate mitochondrial oxidation drives stemness potential in metastatic breast cancer.
Zhang JJ, Tian RF, Song CG, Liu R, He D, Zhang GQ, Fan XY, Duan ZC, Zhang K, Zhang TJ, Chen YT, Zhang J, Wang K, Zhao JM, Yang XM, Chen ZN, Li L
Nature communications 2025 Dec 18;17(1):399
Nature communications 2025 Dec 18;17(1):399
Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity.
Li Y, Sheng M, Li W, Liu S, Wang B, Liu B, Luo M, Zhou X, Xia Q, Hong S, Zheng Z, Cheng SY, Jiang X, Li J, Huang T
Nature communications 2025 Dec 13;17(1):440
Nature communications 2025 Dec 13;17(1):440
The DRP1 inhibitory peptide P110 provides neuroprotection after subarachnoid hemorrhage by suppressing neuronal apoptosis and stabilizing the blood-brain barrier.
Hao S, Luo J, Yuan S, Chen W, Zhang X, Zhao C, Xu H, Liu Z, Zhang D
Free radical biology & medicine 2025 Dec 1;240:1-14
Free radical biology & medicine 2025 Dec 1;240:1-14
Ceftriaxone alleviates mitochondrial damage through the inhibition of extrasynaptic NMDA receptor-mediated changes in intracellular calcium levels to improve cognitive deficits in APP/PS1 mice.
Liu LR, Li L, Lu LL, Fan SJ, Liu LZ, He RB, Li H, Xian XH, Li WB
Alzheimer's research & therapy 2025 Dec 1;17(1):253
Alzheimer's research & therapy 2025 Dec 1;17(1):253
A novel modulator of IL-6R prevents inflammation-induced preterm birth and improves newborn outcome.
Côté F, Prairie E, Sierra EM, Quiniou C, Habelrih T, Xu W, Ferri B, Hou X, Lahaie I, Côté N, Loiselle SE, Gobeil L, Sawaya K, Faucher A, Beaulieu A, Delisle S, Simard MP, Mohammad Nezhady MA, Laplante V, Reuben A, Kalaidji SM, Bajon E, Cagnone G, Leimert KB, Gauchat JF, Gaudreau L, Robertson S, Lubell WD, Olson DM, Chemtob S
EMBO molecular medicine 2025 Aug;17(8):1950-1982
EMBO molecular medicine 2025 Aug;17(8):1950-1982
RONIN/HCF1-TFEB Axis Protects Against D-Galactose-Induced Cochlear Hair Cell Senescence Through Autophagy Activation.
Wei Y, Zhang Y, Cao W, Cheng N, Xiao Y, Zhu Y, Xu Y, Zhang L, Guo L, Song J, Sha SH, Shao B, Ma F, Yang J, Ying Z, He Z, Chai R, Fang Q, Yang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e2407880
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(29):e2407880
c-FLIP Protects Cardiac Microcirculation in Sepsis-Induced Myocardial Dysfunction Via FUNDC1-Mediated Regulation of Mitochondrial Autophagy.
Gao L, Shi Q, Sun B, Zhang X, Zheng P, Zhou L, Tian G, Li H
JACC. Basic to translational science 2025 Aug;10(8):101257
JACC. Basic to translational science 2025 Aug;10(8):101257
Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming.
Zhao T, He L, Wong LP, Mei S, Xia J, Xu Y, Van Vranken JG, Mazzola M, Chen L, Rhee C, Fang T, Fukushima T, Sayles LC, Diaz M, Gibbons JAB, Mostoslavsky R, Gygi SP, Dou Z, Sykes DB, Sadreyev RI, Sweet-Cordero EA, Scadden DT
Cell metabolism 2025 Aug 5;37(8):1667-1681.e13
Cell metabolism 2025 Aug 5;37(8):1667-1681.e13
RNA triggers chronic stress during neuronal aging.
Rhine K, Epstein E, Carlson NM, Ge X, Mizrahi O, Kamat A, Hermann A, Brothers WR, Ravits J, Bennett EJ, Pekkurnaz G, Yeo GW
bioRxiv : the preprint server for biology 2025 Aug 5;
bioRxiv : the preprint server for biology 2025 Aug 5;
Ankyrin-B modulates mitochondrial fission in skeletal muscle and is required for optimal endurance exercise capacity.
Voos KM, Tzeng J, Patel P, Rubinsky S, Choi HE, Pharr T, Sookram S, Baur JA, Soderblom EJ, Lorenzo DN
Nature communications 2025 Aug 25;16(1):7671
Nature communications 2025 Aug 25;16(1):7671
Dual-key cooperatively activated DNA regulator for controlling mitochondria-lysosome interactions.
Xiao Y, Zhu L, Du S, Ge X, Ma L, Deng S, Ren K
Nature communications 2025 Aug 22;16(1):7811
Nature communications 2025 Aug 22;16(1):7811
MRPL13 enhances mitochondrial function and promotes tumor progression in ovarian cancer by inhibiting mPTP opening via SLC25A6.
Liu O, Hu Y, Wang S, Nie X, Wang Y, Fan X, Zeng K, Li X, Liu B, Lin B
Cell death & disease 2025 Aug 21;16(1):634
Cell death & disease 2025 Aug 21;16(1):634
PGAM5 aggravated doxorubicin-induced cardiotoxicity by disturbing mitochondrial dynamics and exacerbating cardiomyocytes apoptosis.
He W, Wang J, He W, Zeng L, Zhao R, Qiu K, Tong G, Sun Z, He P
Free radical biology & medicine 2025 Aug 1;235:95-108
Free radical biology & medicine 2025 Aug 1;235:95-108
Olfactory mucosa mesenchymal stem cell-derived exosomes protect against neuroinflammation after subarachnoid hemorrhage by activating mitophagy.
Wang J, Peng J, Gao L, He J, Lin L, Li JM, Xia Y
The Kaohsiung journal of medical sciences 2025 Apr;41(4):e12951
The Kaohsiung journal of medical sciences 2025 Apr;41(4):e12951
Targeting SARM1 as a novel neuroprotective therapy in neurotropic viral infections.
He S, Zhu Y, Wang X, Zhang G, Hou K, Xia X, Jiang Z, Gong X, Zhao P
Journal of neuroinflammation 2025 Apr 20;22(1):113
Journal of neuroinflammation 2025 Apr 20;22(1):113
Loss of lipid droplet-mitochondria contacts confers protection against ethanol-induced cardiotoxicity.
He W, He W, Zeng L, Zhao R, Qiu K, He P, Sun Z, Tan N
Experimental cell research 2025 Apr 15;447(2):114517
Experimental cell research 2025 Apr 15;447(2):114517
Microvesicles carrying EV71 virions cross BBB through endocytic pathway to induce brain injury.
Tian X, Liu B, Li L, Yuan M, You Q, Zhang R, Chen D, Cheng M, Zheng N, He M, Wu Z
Cell communication and signaling : CCS 2025 Apr 14;23(1):183
Cell communication and signaling : CCS 2025 Apr 14;23(1):183
Alda-1 mediates cell senescence and counteracts bone loss in weightlessness through regulating mitophagy.
Wang J, Li S, Li Q, Yan Q, Wang Y, Zeng X, Yang F, Jiang S, Zhang M, Pi Y, Tahir R, Wei L
Life sciences 2025 Apr 1;366-367:123482
Life sciences 2025 Apr 1;366-367:123482
Hypoxia-preconditioned bone marrow-derived mesenchymal stem cells protect neurons from cardiac arrest-induced pyroptosis.
Tang X, Zheng N, Lin Q, You Y, Gong Z, Zhuang Y, Wu J, Wang Y, Huang H, Ke J, Chen F
Neural regeneration research 2025 Apr 1;20(4):1103-1123
Neural regeneration research 2025 Apr 1;20(4):1103-1123
REGγ deficiency ameliorates hepatic ischemia and reperfusion injury in a mitochondrial p66shc dependent manner in mice.
Guo L, Yang Q, Zhu J, Li J
Translational gastroenterology and hepatology 2024;9:62
Translational gastroenterology and hepatology 2024;9:62
Schisandrin a Ameliorates Cardiac Injury and Dysfunction Induced by Hemorrhagic Shock via Activating the Nrf2 Signaling Pathway.
Li B, Zhou W, Zhang J, Wang N, Yang X, Ge X
The American journal of Chinese medicine 2024;52(8):2453-2468
The American journal of Chinese medicine 2024;52(8):2453-2468
A liver-fat crosstalk for iron flux during healthy beiging of adipose tissue.
Yang J, Shi L, Cubito AL, Collins JF, Cheng Z
Autophagy reports 2024;3(1):2396696
Autophagy reports 2024;3(1):2396696
Jagged 2 inhibition attenuates hypoxia-induced mitochondrial damage and pulmonary hypertension through Sirtuin 1 signaling.
Liu H, Pan Z, Wu X, Gong C, Hu J
PloS one 2024;19(1):e0297525
PloS one 2024;19(1):e0297525
Mitochondria-Rich Microvesicles Alleviate CNI ED by Transferring Mitochondria and Suppressing Local Ferroptosis.
Liang Z, Chen Z, Zhang C, Chen C, Yang W, Zhang Y, Wei H
International journal of nanomedicine 2024;19:11745-11765
International journal of nanomedicine 2024;19:11745-11765
5-Methoxytryptophan Alleviates Lipopolysaccharide-Induced Acute Kidney Injury by Regulating Nrf2-Mediated Mitophagy.
Sun X, Wang H, Liu Y, Yang Y, Wang Y, Liu Y, Ai S, Shan Z, Luo P
Journal of inflammation research 2024;17:9857-9873
Journal of inflammation research 2024;17:9857-9873
NLRP3 Inflammasome Deficiency Alleviates Inflammation and Oxidative Stress by Promoting PINK1/Parkin-Mediated Mitophagy in Allergic Rhinitis Mice and Nasal Epithelial Cells.
Ding H, Lu X, Wang H, Chen W, Niu B
Journal of asthma and allergy 2024;17:717-731
Journal of asthma and allergy 2024;17:717-731
Novel bi-allelic DNAH3 variants cause oligoasthenoteratozoospermia.
Li S, Zhang Z, Xie L, Zhao Y, Chen H, Zhang S, Cai Y, Ren B, Liu W, Tang S, Sha Y
Frontiers in endocrinology 2024;15:1462509
Frontiers in endocrinology 2024;15:1462509
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux.
He W, Sun Z, Tong G, Zeng L, He W, Chen X, Zhen C, Chen P, Tan N, He P
Theranostics 2024;14(9):3719-3738
Theranostics 2024;14(9):3719-3738
The mitochondria‒paraspeckle axis regulates the survival of transplanted stem cells under oxidative stress conditions.
Zhao M, Liu S, Wang Y, Lv K, Lou P, Zhou P, Zhu J, Li L, Cheng J, Lu Y, Liu J
Theranostics 2024;14(4):1517-1533
Theranostics 2024;14(4):1517-1533
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke.
Wang Y, Bai Y, Cai Y, Zhang Y, Shen L, Xi W, Zhou Z, Xu L, Liu X, Han B, Yao H
Theranostics 2024;14(19):7292-7308
Theranostics 2024;14(19):7292-7308
β-arrestin1 protects intestinal tight junction through promoting mitofusin 2 transcription to drive parkin-dependent mitophagy in colitis.
Wu S, Liu H, Yi J, Xu M, Jiang J, Tao J, Wu B
Gastroenterology report 2024;12:goae084
Gastroenterology report 2024;12:goae084
Melatonin Alleviates Osteoarthritis by Regulating NADPH Oxidase 4-Induced Ferroptosis and Mitigating Mitochondrial Dysfunction.
Wang Q, Qi B, Shi S, Jiang W, Li D, Jiang X, Yi C
Journal of pineal research 2024 Sep;76(6):e12992
Journal of pineal research 2024 Sep;76(6):e12992
HSPB8 attenuates lipopolysaccharide‑mediated acute lung injury in A549 cells by activating mitophagy.
Zhou X, Wang M, Sun M, Yao N
Molecular medicine reports 2024 Sep;30(3)
Molecular medicine reports 2024 Sep;30(3)
LONP1 alleviates ageing-related renal fibrosis by maintaining mitochondrial homeostasis.
Zhang C, Shen S, Xu L, Li M, Tian B, Yao L, Zhu X
Journal of cellular and molecular medicine 2024 Sep;28(17):e70090
Journal of cellular and molecular medicine 2024 Sep;28(17):e70090
The one-carbon metabolic enzyme MTHFD2 promotes resection and homologous recombination after ionizing radiation.
Marttila P, Bonagas N, Chalkiadaki C, Stigsdotter H, Schelzig K, Shen J, Farhat CM, Hondema A, Albers J, Wiita E, Rasti A, Warpman Berglund U, Slipicevic A, Mortusewicz O, Helleday T
Molecular oncology 2024 Sep;18(9):2179-2195
Molecular oncology 2024 Sep;18(9):2179-2195
Cocoa extract induces browning of white adipocytes and improves glucose intolerance in mice fed a high-fat diet.
Yonemoto E, Ihara R, Tanaka E, Mitani T
Bioscience, biotechnology, and biochemistry 2024 Sep 20;88(10):1188-1198
Bioscience, biotechnology, and biochemistry 2024 Sep 20;88(10):1188-1198
Substrate-Mediated Regulation of Src Expression Drives Osteoclastogenesis Divergence.
Hu B, Chen Y, Li Y, Deng C, Niu Y, Hu Z, Li Y, Sun S, Huang Y, Deng X, Wei Y
Genes 2024 Sep 18;15(9)
Genes 2024 Sep 18;15(9)
Strategically engineered Au(I) complexes for orchestrated tumor eradication via chemo-phototherapy and induced immunogenic cell death.
Feng N, Peng Z, Zhang X, Lin Y, Hu L, Zheng L, Tang BZ, Zhang J
Nature communications 2024 Sep 18;15(1):8187
Nature communications 2024 Sep 18;15(1):8187
Glucose-1,6-bisphosphate: A new gatekeeper of cerebral mitochondrial pyruvate uptake.
Safari MS, Woerl P, Garmsiri C, Weber D, Kwiatkowski M, Hotze M, Kuenkel L, Lang L, Erlacher M, Gelpi E, Hainfellner JA, Baier G, Baier-Bitterlich G, Zur Nedden S
Molecular metabolism 2024 Oct;88:102018
Molecular metabolism 2024 Oct;88:102018
Mitochondrial Dysfunction due to Novel COQ8A Variation with Poor Response to CoQ10 Treatment: A Comprehensive Study and Review of Literatures.
Wang J, Lin Y, Xu Z, Yan C, Zhao Y, Ji K
Cerebellum (London, England) 2024 Oct;23(5):1824-1838
Cerebellum (London, England) 2024 Oct;23(5):1824-1838
Low-dose radiation promotes high-fat diet-induced atherosclerosis by activating cGAS signal pathway.
Liu X, Huang X, Luo J, Gao SN, Bai C, Xie D, Gao SS, Guan H, Huang R, Zhou PK
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167443
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167443
CHIP drives proteasomal degradation of NUR77 to alleviate oxidative stress and intrinsic apoptosis in cisplatin-induced nephropathy.
Zhang H, Deng Z, Wang Y, Zheng X, Zhou L, Yan S, Wang Y, Dai Y, Kanwar YS, Chen F, Deng F
Communications biology 2024 Oct 26;7(1):1403
Communications biology 2024 Oct 26;7(1):1403
Mitochondrial fatty acid oxidation drives senescence.
Yamauchi S, Sugiura Y, Yamaguchi J, Zhou X, Takenaka S, Odawara T, Fukaya S, Fujisawa T, Naguro I, Uchiyama Y, Takahashi A, Ichijo H
Science advances 2024 Oct 25;10(43):eado5887
Science advances 2024 Oct 25;10(43):eado5887
Reduced expression of NUPR1 alleviates epilepsy progression via attenuating ER stress.
Cui Y, Yang G, Li H, Sun J, Liu X, Xia X
Biochemical and biophysical research communications 2024 Oct 20;730:150365
Biochemical and biophysical research communications 2024 Oct 20;730:150365
TRPC6-Calpain-1 Axis Promotes Tubulointerstitial Inflammation by Inhibiting Mitophagy in Diabetic Kidney Disease.
Liu CC, Ji JL, Wang Z, Zhang XJ, Ding L, Zhang Y, Zhou Y, Zhang DJ, Tang ZL, Cao JY, Zhang AQ, Liu BC, Li ZL, Ma RX
Kidney international reports 2024 Nov;9(11):3301-3317
Kidney international reports 2024 Nov;9(11):3301-3317
Long non-coding RNA MALAT1 triggers ferroptosis via interaction with FUS to enhance ACSF2 mRNA stabilization in septic acute kidney injury.
Duan ZB, Zheng JF, Huang SY, Hu LL
The Kaohsiung journal of medical sciences 2024 Nov;40(11):972-984
The Kaohsiung journal of medical sciences 2024 Nov;40(11):972-984
The PRMT6/STAT1/ACSL1 axis promotes ferroptosis in diabetic nephropathy.
Hong J, Li X, Hao Y, Xu H, Yu L, Meng Z, Zhang J, Zhu M
Cell death and differentiation 2024 Nov;31(11):1561-1575
Cell death and differentiation 2024 Nov;31(11):1561-1575
Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity.
He W, He W, Chen X, Zeng L, Zeng L, Liu Y, He P, Sun Z
Biochemical pharmacology 2024 Nov;229:116495
Biochemical pharmacology 2024 Nov;229:116495
Emodin alleviates lung injury via the miR-217-5p/Sirt1 axis in rats with severe acute pancreatitis.
Zhang Z, Luo Y, Zhuang X, Gao H, Yang Q, Chen H
Journal of pharmacological sciences 2024 Nov;156(3):188-197
Journal of pharmacological sciences 2024 Nov;156(3):188-197
Taurine hypomodification underlies mitochondrial tRNATrp-related genetic diseases.
Lu JL, Dai Y, Ji K, Peng GX, Li H, Yan C, Shen B, Zhou XL
Nucleic acids research 2024 Nov 27;52(21):13351-13367
Nucleic acids research 2024 Nov 27;52(21):13351-13367
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells.
Lin YH, Lin KL, Wang XW, Lee JJ, Wang FS, Wang PW, Lan MY, Liou CW, Lin TK
Mitochondrion 2024 May;76:101856
Mitochondrion 2024 May;76:101856
Endurance training increases mitochondrial myoglobin and enhances its interaction with complex IV in rat plantaris muscle.
Koma R, Shibaguchi T, Yamada T, Nonaka Y, Jue T, Yamazaki A, Masuda K
Acta physiologica (Oxford, England) 2024 May;240(5):e14139
Acta physiologica (Oxford, England) 2024 May;240(5):e14139
Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia.
Tang Y, Wu J, Sun X, Tan S, Li W, Yin S, Liu L, Chen Y, Liu Y, Tan Q, Jiang Y, Yang W, Huang W, Weng C, Wu Q, Lu Y, Yuan H, Xiao Q, Chen AF, Xu Q, Billiar TR, Cai J
Cell reports 2024 May 28;43(5):114237
Cell reports 2024 May 28;43(5):114237
MicroRNA-142-3p alleviated high salt-induced cardiac fibrosis via downregulating optineurin-mediated mitophagy.
Li Y, Zhao K, Hu Y, Yang F, Li P, Liu Y
iScience 2024 May 17;27(5):109764
iScience 2024 May 17;27(5):109764
Pirin Inhibits FAS-Mediated Apoptosis to Support Colorectal Cancer Survival.
Ma H, Suleman M, Zhang F, Cao T, Wen S, Sun D, Chen L, Jiang B, Wang Y, Lin F, Wang J, Li B, Li Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2301476
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2301476
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
Huang W, Wang L, Huang Z, Sun Z, Zheng B
Respiratory research 2024 Mar 2;25(1):110
Respiratory research 2024 Mar 2;25(1):110
Metformin switches cell death modes to soothe the apical periodontitis via ZBP1.
Liu H, Liu YX, Fan W, Fan B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23549
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 15;38(5):e23549
Proteomic analysis of mitochondria associated membranes in renal ischemic reperfusion injury.
Li Y, Wang HB, Cao JL, Zhang WJ, Wang HL, Xu CH, Li KP, Liu Y, Wang JR, Ha HL, Fu SJ, Yang L
Journal of translational medicine 2024 Mar 10;22(1):261
Journal of translational medicine 2024 Mar 10;22(1):261
Atox1 protects hippocampal neurons after traumatic brain injury via DJ-1 mediated anti-oxidative stress and mitophagy.
Zhao P, Shi W, Ye Y, Xu K, Hu J, Chao H, Tao Z, Xu L, Gu W, Zhang L, Wang T, Wang X, Ji J
Redox biology 2024 Jun;72:103156
Redox biology 2024 Jun;72:103156
Time of exercise differentially impacts bone growth in mice.
Yu S, Tang Q, Lu X, Chen G, Xie M, Yang J, Yin Y, Zheng W, Wang J, Han Y, Zhang L, Chen L
Nature metabolism 2024 Jun;6(6):1036-1052
Nature metabolism 2024 Jun;6(6):1036-1052
Maternal Ezh1/2 deficiency impairs the function of mitochondria in mouse oocytes and early embryos.
Zhang D, Deng W, Jiang T, Zhao Y, Bai D, Tian Y, Kong S, Zhang L, Wang H, Gao S, Lu Z
Journal of cellular physiology 2024 Jun;239(6):e31244
Journal of cellular physiology 2024 Jun;239(6):e31244
Targeting NKAα1 to treat Parkinson's disease through inhibition of mitophagy-dependent ferroptosis.
Zhang X, Li G, Chen H, Nie XW, Bian JS
Free radical biology & medicine 2024 Jun;218:190-204
Free radical biology & medicine 2024 Jun;218:190-204
Cytochrome c oxidase IV isoform 1 (COX4-1) regulates the proliferation, migration and invasion of trophoblast cells via modulating mitochondrial function.
Yu J, Duan Y, Lu Q, Chen M, Ning F, Ye Y, Lu S, Ou D, Sha X, Gan X, Zhao M, Lash GE
Placenta 2024 Jun;151:48-58
Placenta 2024 Jun;151:48-58
Targeting DRP1 with Mdivi-1 to correct mitochondrial abnormalities in ADOA+ syndrome.
Lin Y, Wang D, Li B, Wang J, Xu L, Sun X, Ji K, Yan C, Liu F, Zhao Y
JCI insight 2024 Jun 25;9(15)
JCI insight 2024 Jun 25;9(15)
MYG1 drives glycolysis and colorectal cancer development through nuclear-mitochondrial collaboration.
Chen J, Duan S, Wang Y, Ling Y, Hou X, Zhang S, Liu X, Long X, Lan J, Zhou M, Xu H, Zheng H, Zhou J
Nature communications 2024 Jun 11;15(1):4969
Nature communications 2024 Jun 11;15(1):4969
Static magnetic field-modulated mesenchymal stem cell-derived mitochondria-containing microvesicles for enhanced intervertebral disc degeneration therapy.
Shi P, Gao H, Cheng Z, Zhao K, Chen Y, Chen X, Gan W, Zhang A, Yang C, Zhang Y
Journal of nanobiotechnology 2024 Jul 31;22(1):457
Journal of nanobiotechnology 2024 Jul 31;22(1):457
Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation.
Kopsidas CA, Lowe CC, McDaniel DP, Zhou X, Feng Y
iScience 2024 Jul 19;27(7):110199
iScience 2024 Jul 19;27(7):110199
Tafazzin mediates tamoxifen resistance by regulating cellular phospholipid composition in ER-positive breast cancer.
Li X, Zhang Y, Zhang T, Zhao L, Lin CG, Hu H, Zheng H
Cancer gene therapy 2024 Jan;31(1):69-81
Cancer gene therapy 2024 Jan;31(1):69-81
Suppression of NLRP3 inflammasome activation by astragaloside IV via promotion of mitophagy to ameliorate radiation-induced renal injury in mice.
Ding Y, Liu S, Zhang M, Su M, Shao B
Translational andrology and urology 2024 Jan 31;13(1):25-41
Translational andrology and urology 2024 Jan 31;13(1):25-41
AKT1 phosphorylation of cytoplasmic ME2 induces a metabolic switch to glycolysis for tumorigenesis.
Chen T, Xie S, Cheng J, Zhao Q, Wu H, Jiang P, Du W
Nature communications 2024 Jan 23;15(1):686
Nature communications 2024 Jan 23;15(1):686
Network pharmacology and experimental validation on yangjing zhongyu decoction against diminished ovarian reserve.
Liu J, Wei B, Ma Q, Shi D, Pan X, Liu Z, Li J, Zhao P
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117023
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117023
Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer's Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice.
Zhu Y, Huang H, Chen Z, Tao Y, Liao LY, Gao SH, Wang YJ, Gao CY
Neuroscience bulletin 2024 Feb;40(2):182-200
Neuroscience bulletin 2024 Feb;40(2):182-200
Axonal injury mediated by neuronal p75NTR/TRAF6/JNK pathway contributes to cognitive impairment after repetitive mTBI.
Liu G, He M, Wu C, Lv P, Sun H, Wang H, Xin X, Liao H
Experimental neurology 2024 Feb;372:114618
Experimental neurology 2024 Feb;372:114618
Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis.
Xu J, Shi C, Yuan F, Ding Y, Xie Y, Liu Y, Zhu F, Lu H, Duan C, Hu J, Jiang L
Bioactive materials 2024 Feb;32:427-444
Bioactive materials 2024 Feb;32:427-444
A new andrographolide derivative ADA targeting SIRT3-FOXO3a signaling mitigates cognitive impairment by activating mitophagy and inhibiting neuroinflammation in Apoe4 mice.
Zhou Y, Zhao Q, Zhang Y, Di L, Xue F, Xu W, Gao W, Guo Y, He Y, Kou J, Qin Y, Xie X, Du L, Han G, Pang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155298
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155298
AMPK phosphorylation of FNIP1 (S220) controls mitochondrial function and muscle fuel utilization during exercise.
Xiao L, Yin Y, Sun Z, Liu J, Jia Y, Yang L, Mao Y, Peng S, Xie Z, Fang L, Li J, Xie X, Gan Z
Science advances 2024 Feb 9;10(6):eadj2752
Science advances 2024 Feb 9;10(6):eadj2752
SERCA2 dysfunction triggers hypertension by interrupting mitochondrial homeostasis and provoking oxidative stress.
Wang Y, Wang M, Su H, Song J, Ren M, Hu P, Liu G, Tong X
Free radical biology & medicine 2024 Feb 20;212:284-294
Free radical biology & medicine 2024 Feb 20;212:284-294
Zbtb16 increases susceptibility of atrial fibrillation in type 2 diabetic mice via Txnip-Trx2 signaling.
Wei ZX, Cai XX, Fei YD, Wang Q, Hu XL, Li C, Hou JW, Yang YL, Chen TZ, Xu XL, Wang YP, Li YG
Cellular and molecular life sciences : CMLS 2024 Feb 13;81(1):88
Cellular and molecular life sciences : CMLS 2024 Feb 13;81(1):88
Sacubitril/valsartan ameliorates tubulointerstitial fibrosis by restoring mitochondrial homeostasis in diabetic kidney disease.
Zhang XJ, Liu CC, Li ZL, Ding L, Zhou Y, Zhang DJ, Zhang Y, Hou ST, Ma RX
Diabetology & metabolic syndrome 2024 Feb 10;16(1):40
Diabetology & metabolic syndrome 2024 Feb 10;16(1):40
PX-478 induces apoptosis in acute myeloid leukemia under hypoxia by inhibiting the PI3K/AKT/mTOR pathway through downregulation of GBE1.
Liu W, Dou C, Zhang C, Chen P, Zhang S, Wang R, Han Q, Zhao H, Li D
Biochemical pharmacology 2024 Dec;230(Pt 3):116620
Biochemical pharmacology 2024 Dec;230(Pt 3):116620
Regulatory roles of histamine receptor in astrocytic glutamate clearance under conditions of increased glucose variability.
Zhou Y, Xie W, Kong C, Luo W, Wei H, Zheng J
Biochemical pharmacology 2024 Dec;230(Pt 3):116611
Biochemical pharmacology 2024 Dec;230(Pt 3):116611
New TIPARP inhibitor rescues mitochondrial function and brain injury in ischemic stroke.
Cai Y, Gu H, Li L, Liu X, Bai Y, Shen L, Han B, Xu Y, Yao H
Pharmacological research 2024 Dec;210:107508
Pharmacological research 2024 Dec;210:107508
Protein kinase N1 deficiency results in upregulation of cerebral energy metabolism and is highly protective in in vivo and in vitro stroke models.
Zur Nedden S, Safari MS, Weber D, Kuenkel L, Garmsiri C, Lang L, Orset C, Freret T, Haelewyn B, Hotze M, Kwiatkowski M, Sarg B, Faserl K, Savic D, Skvortsova II, Krogsdam A, Carollo S, Trajanoski Z, Oberacher H, Zlotek D, Ostermaier F, Cameron A, Baier G, Baier-Bitterlich G
Metabolism: clinical and experimental 2024 Dec;161:156039
Metabolism: clinical and experimental 2024 Dec;161:156039
Ginsenoside compound K alleviates brain aging by inhibiting ferroptosis through modulation of the ASK1-MKK7-JNK signaling pathway.
Yan X, Bai X, Sun G, Duan Z, Fu R, Zeng W, Zhu C, Fan D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156239
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156239
Targeting BRIX1 via Engineered Exosomes Induces Nucleolar Stress to Suppress Cancer Progression.
Gan Y, Hao Q, Han T, Tong J, Yan Q, Zhong H, Gao B, Li Y, Xuan Z, Li P, Yao L, Xu Y, Jiang YZ, Shao ZM, Deng J, Chen J, Zhou X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(47):e2407370
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(47):e2407370
Conjugated fatty acids drive ferroptosis through chaperone-mediated autophagic degradation of GPX4 by targeting mitochondria.
Hirata Y, Yamada Y, Taguchi S, Kojima R, Masumoto H, Kimura S, Niijima T, Toyama T, Kise R, Sato E, Uchida Y, Ito J, Nakagawa K, Taguchi T, Inoue A, Saito Y, Noguchi T, Matsuzawa A
Cell death & disease 2024 Dec 6;15(12):884
Cell death & disease 2024 Dec 6;15(12):884
Subcellular Proteomic Mapping of Lysine Lactylation.
Bao Q, Wan N, He Z, Cao J, Yuan W, Hao H, Ye H
Journal of the American Society for Mass Spectrometry 2024 Dec 4;35(12):3221-3232
Journal of the American Society for Mass Spectrometry 2024 Dec 4;35(12):3221-3232
Boosting neuronal activity-driven mitochondrial DNA transcription improves cognition in aged mice.
Li W, Li J, Li J, Wei C, Laviv T, Dong M, Lin J, Calubag M, Colgan LA, Jin K, Zhou B, Shen Y, Li H, Cui Y, Gao Z, Li T, Hu H, Yasuda R, Ma H
Science (New York, N.Y.) 2024 Dec 20;386(6728):eadp6547
Science (New York, N.Y.) 2024 Dec 20;386(6728):eadp6547
Lysosomes drive the piecemeal removal of mitochondrial inner membrane.
Prashar A, Bussi C, Fearns A, Capurro MI, Gao X, Sesaki H, Gutierrez MG, Jones NL
Nature 2024 Aug;632(8027):1110-1117
Nature 2024 Aug;632(8027):1110-1117
The VDAC1 oligomerization regulated by ATP5B leads to the NLRP3 inflammasome activation in the liver cells under PFOS exposure.
Ma Y, Yang W, Liang P, Feng R, Qiu T, Zhang J, Sun X, Li Q, Yang G, Yao X
Ecotoxicology and environmental safety 2024 Aug;281:116647
Ecotoxicology and environmental safety 2024 Aug;281:116647
PGC-1α/LDHA signaling facilitates glycolysis initiation to regulate mechanically induced bone remodeling under inflammatory microenvironment.
Liu J, Wang J, Wang Z, Ren H, Zhang Z, Fu Y, Li L, Shen Z, Li T, Tang S, Wei F
Bone 2024 Aug;185:117132
Bone 2024 Aug;185:117132
Comparison of the stage-dependent mitochondrial changes in response to pressure overload between the diseased right and left ventricle in the rat.
Li L, Niemann B, Knapp F, Werner S, Mühlfeld C, Schneider JP, Jurida LM, Molenda N, Schmitz ML, Yin X, Mayr M, Schulz R, Kracht M, Rohrbach S
Basic research in cardiology 2024 Aug;119(4):587-611
Basic research in cardiology 2024 Aug;119(4):587-611
Carcinoma-associated mesenchymal stem cells promote ovarian cancer heterogeneity and metastasis through mitochondrial transfer.
Frisbie L, Pressimone C, Dyer E, Baruwal R, Garcia G, St Croix C, Watkins S, Calderone M, Gorecki G, Javed Z, Atiya HI, Hempel N, Pearson A, Coffman LG
Cell reports 2024 Aug 27;43(8):114551
Cell reports 2024 Aug 27;43(8):114551
Queuine ameliorates impaired mitochondrial function caused by mt-tRNA(Asn) variants.
Lin Y, Wang J, Zhuang X, Zhao Y, Wang W, Wang D, Zhao Y, Yan C, Ji K
Journal of translational medicine 2024 Aug 22;22(1):780
Journal of translational medicine 2024 Aug 22;22(1):780
DsbA-L ameliorates renal aging and renal fibrosis by maintaining mitochondrial homeostasis.
Yang M, Liu Y, Luo SL, Liu CB, Jiang N, Li CR, Zhao H, Han YC, Chen W, Li L, Sun L
Acta pharmacologica Sinica 2024 Apr;45(4):777-789
Acta pharmacologica Sinica 2024 Apr;45(4):777-789
SIRT3 alleviates painful diabetic neuropathy by mediating the FoxO3a-PINK1-Parkin signaling pathway to activate mitophagy.
Yang J, Yu Z, Jiang Y, Zhang Z, Tian Y, Cai J, Wei M, Lyu Y, Yang D, Shen S, Xing GG, Li M
CNS neuroscience & therapeutics 2024 Apr;30(4):e14703
CNS neuroscience & therapeutics 2024 Apr;30(4):e14703
Resveratrol Inhibits Zinc Deficiency-Induced Mitophagy and Exerts Cardiac Cytoprotective Effects.
Wang P, Yang Y, Guo J, Ma T, Hu Y, Huang L, He Y, Xi J
Biological trace element research 2024 Apr;202(4):1669-1682
Biological trace element research 2024 Apr;202(4):1669-1682
The surface morphology of Atractylodes macrocephala polysaccharide and its inhibitory effect on PCV2 replication.
Qi C, Lv C, Jiang M, Zhao X, Gao Y, Wang Y, Zhang P, Liu J, Zhao X
Journal of the science of food and agriculture 2024 Apr;104(6):3624-3636
Journal of the science of food and agriculture 2024 Apr;104(6):3624-3636
Taurine ameliorates sensorimotor function by inhibiting apoptosis and activating A2 astrocytes in mice after subarachnoid hemorrhage.
Yang C, Jiang Z, Gao X, Yang H, Su J, Weng R, Ni W, Gu Y
Amino acids 2024 Apr 14;56(1):31
Amino acids 2024 Apr 14;56(1):31
Cardiolipin externalization mediates prion protein (PrP) peptide 106-126-associated mitophagy and mitochondrial dysfunction.
Yang D, Li J, Li Z, Zhao M, Wang D, Sun Z, Wen P, Gou F, Dai Y, Ji Y, Li W, Zhao D, Yang L
Frontiers in molecular neuroscience 2023;16:1163981
Frontiers in molecular neuroscience 2023;16:1163981
A novel mutation in CFAP47 causes male infertility due to multiple morphological abnormalities of the sperm flagella.
Liu M, Dai S, Zhang J, Yang Y, Shen Y, Liu H, Yang Y, Jiang C, Tian E
Frontiers in endocrinology 2023;14:1155639
Frontiers in endocrinology 2023;14:1155639
Electroacupuncture preconditioning protects against myocardial ischemia-reperfusion injury by modulating dynamic inflammatory response.
Bai H, Xu SL, Shi JJ, Ding YP, Liu QQ, Jiang CH, He LL, Zhang HR, Lu SF, Gu YH
Heliyon 2023 Sep;9(9):e19396
Heliyon 2023 Sep;9(9):e19396
MAVI1, an endoplasmic reticulum-localized microprotein, suppresses antiviral innate immune response by targeting MAVS on mitochondrion.
Shi TT, Huang Y, Li Y, Dai XL, He YH, Ding JC, Ran T, Shi Y, Yuan Q, Li WJ, Liu W
Science advances 2023 Sep;9(35):eadg7053
Science advances 2023 Sep;9(35):eadg7053
Ginsenoside Rh4 delays skeletal muscle aging through SIRT1 pathway.
Zhu A, Duan Z, Chen Y, Zhu C, Fan D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154906
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154906
UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture.
Ma Q, Xin J, Peng Q, Li N, Sun S, Hou H, Ma G, Wang N, Zhang L, Tam KY, Dussmann H, Prehn JH, Wang H, Ying Z
EMBO reports 2023 Sep 6;24(9):e55859
EMBO reports 2023 Sep 6;24(9):e55859
Crotonylated BEX2 interacts with NDP52 and enhances mitophagy to modulate chemotherapeutic agent-induced apoptosis in non-small-cell lung cancer cells.
Mu N, Wang Y, Li X, Du Z, Wu Y, Su M, Wang Y, Sun X, Su L, Liu X
Cell death & disease 2023 Sep 30;14(9):645
Cell death & disease 2023 Sep 30;14(9):645
The lysosome-mitochondrion crosstalk engaged in silver nanoparticles-disturbed mitochondrial homeostasis.
Liu J, Huang Z, Yin S, Zhou X, Jiang Y, Shao L
The Science of the total environment 2023 Sep 1;889:164078
The Science of the total environment 2023 Sep 1;889:164078
Mitochondrial dysfunction and calcium dysregulation in COQ8A-ataxia Purkinje neurons are rescued by CoQ10 treatment.
Manolaras I, Del Bondio A, Griso O, Reutenauer L, Eisenmann A, Habermann BH, Puccio H
Brain : a journal of neurology 2023 Sep 1;146(9):3836-3850
Brain : a journal of neurology 2023 Sep 1;146(9):3836-3850
COX17 restricts renal fibrosis development by maintaining mitochondrial copper homeostasis and restoring complex IV activity.
Zhu SY, Zhou WQ, Niu YY, Zheng C, Liu X, Zhang YY, Yu C
Acta pharmacologica Sinica 2023 Oct;44(10):2091-2102
Acta pharmacologica Sinica 2023 Oct;44(10):2091-2102
Kinsenoside mitigates myocardial ischemia/reperfusion-induced ferroptosis via activation of the Akt/Nrf2/HO-1 pathway.
Wang R, Dong S, Xia R, Sun M, Sun Y, Ren H, Zhang Y, Xia Z, Yao S, Wang T
European journal of pharmacology 2023 Oct 5;956:175985
European journal of pharmacology 2023 Oct 5;956:175985
Afzelin protects against doxorubicin-induced cardiotoxicity by promoting the AMPKα/SIRT1 signaling pathway.
Sun Y, Guo D, Yue S, Zhou M, Wang D, Chen F, Wang L
Toxicology and applied pharmacology 2023 Oct 15;477:116687
Toxicology and applied pharmacology 2023 Oct 15;477:116687
Matrix stiffness induces Drp1-mediated mitochondrial fission through Piezo1 mechanotransduction in human intervertebral disc degeneration.
Ke W, Wang B, Liao Z, Song Y, Li G, Ma L, Wang K, Li S, Hua W, Yang C
Journal of translational medicine 2023 Oct 10;21(1):711
Journal of translational medicine 2023 Oct 10;21(1):711
Endoplasmic reticulum-mitochondrial calcium transport contributes to soft extracellular matrix-triggered mitochondrial dynamics and mitophagy in breast carcinoma cells.
Chen Y, Li P, Chen X, Yan R, Zhang Y, Wang M, Qin X, Li S, Zheng C, You F, Li T, Liu Y
Acta biomaterialia 2023 Oct 1;169:192-208
Acta biomaterialia 2023 Oct 1;169:192-208
Acid ground nano-realgar processed product inhibits breast cancer by inducing mitophagy via the p53/BNIP3/NIX pathway.
Fang J, Zou X, Gong L, Xi J, Liu Y, Yang X, Zhang X, Gui C
Journal of cellular and molecular medicine 2023 Nov;27(22):3478-3490
Journal of cellular and molecular medicine 2023 Nov;27(22):3478-3490
Glutathione Might Attenuate Arsenic-Induced Liver Injury by Modulating the Foxa2-XIAP Axis to Reduce Oxidative Stress and Mitochondrial Apoptosis.
Zhang H, Jin B, Liu L, Li H, Zheng X, Li M, He R, Wang K
Biological trace element research 2023 Nov;201(11):5201-5212
Biological trace element research 2023 Nov;201(11):5201-5212
Miquelianin in Folium Nelumbinis extract promotes white-to-beige fat conversion via blocking AMPK/DRP1/mitophagy and modulating gut microbiota in HFD-fed mice.
Wang Z, Yang T, Zeng M, Wang Z, Chen Q, Chen J, Christian M, He Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114089
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114089
Methylcrotonyl-CoA carboxylase subunit 1 (MCCA) regulates multidrug resistance in multiple myeloma.
Feng Y, Huang J, Wang F, Lin Z, Luo H, Li Q, Wang X, Liu X, Zhai X, Gao Q, Li L, Zhang Y, Wen J, Zhang L, Niu T, Zheng Y
Life sciences 2023 Nov 15;333:122157
Life sciences 2023 Nov 15;333:122157
Interactome profiling of Crimean-Congo hemorrhagic fever virus glycoproteins.
Dai S, Min YQ, Li Q, Feng K, Jiang Z, Wang Z, Zhang C, Ren F, Fang Y, Zhang J, Zhu Q, Wang M, Wang H, Deng F, Ning YJ
Nature communications 2023 Nov 14;14(1):7365
Nature communications 2023 Nov 14;14(1):7365
CX3CR1(hi) macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue.
Zhou Z, Zhang H, Tao Y, Jie H, Zhao J, Zang J, Li H, Wang Y, Wang T, Zhao H, Li Y, Guo C, Zhu F, Mao H, Zhang L, Liu F, Wang Q
Cell reports 2023 May 30;42(5):112424
Cell reports 2023 May 30;42(5):112424
MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells.
Ji X, Chu L, Su D, Sun J, Song P, Sun S, Wang Y, Mu Q, Liu Y, Wan Q
iScience 2023 May 19;26(5):106656
iScience 2023 May 19;26(5):106656
Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats.
Wang Y, Miao Z, Xu C, Cai Y, Yang Y, Hu Y, Zhao M, Shao Y, Li Z, Chen J, Chen S, Wang L
Cell death & disease 2023 May 13;14(5):325
Cell death & disease 2023 May 13;14(5):325
RAB7A GTPase Is Involved in Mitophagosome Formation and Autophagosome-Lysosome Fusion in N2a Cells Treated with the Prion Protein Fragment 106-126.
Li Z, Lai M, Li J, Yang D, Zhao M, Wang D, Sun Z, Wen P, Gou F, Dai Y, Ji Y, Zhao D, Qiao J, Yang L
Molecular neurobiology 2023 Mar;60(3):1391-1407
Molecular neurobiology 2023 Mar;60(3):1391-1407
Inhibition of ACSF2 protects against renal ischemia/reperfusion injury via mediating mitophagy in proximal tubular cells.
Shi H, Qi H, Xie D, Zhuang J, Qi H, Dai Y, Wu J
Free radical biology & medicine 2023 Mar;198:68-82
Free radical biology & medicine 2023 Mar;198:68-82
MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model.
Shahin S, Lu B, Zhou Y, Xu H, Chetsawang J, Baloh RH, Wang S
iScience 2023 Mar 17;26(3):106270
iScience 2023 Mar 17;26(3):106270
STOML2 restricts mitophagy and increases chemosensitivity in pancreatic cancer through stabilizing PARL-induced PINK1 degradation.
Qin C, Wang Y, Zhao B, Li Z, Li T, Yang X, Zhao Y, Wang W
Cell death & disease 2023 Mar 11;14(3):191
Cell death & disease 2023 Mar 11;14(3):191
The immunity-related GTPase IRGC mediates interaction between lipid droplets and mitochondria to facilitate sperm motility.
Li J, Xu X, Liu J, Zhang S, Wang T, Liu Y, Wang Z
FEBS letters 2023 Jun;597(12):1595-1605
FEBS letters 2023 Jun;597(12):1595-1605
Toosendanin-induced apoptosis of CMT-U27 is mediated through the mitochondrial apoptotic pathway.
Yang Y, Mei C, Xian H, Zhang X, Li J, Liang ZX, Zhi Y, Ma Y, Wang HJ
Veterinary and comparative oncology 2023 Jun;21(2):315-326
Veterinary and comparative oncology 2023 Jun;21(2):315-326
Necroptosis signaling and mitochondrial dysfunction cross-talking facilitate cell death mediated by chelerythrine in glioma.
Wang P, Zheng SY, Jiang RL, Wu HD, Li YA, Lu JL, Xiong Y, Han B, Lin L
Free radical biology & medicine 2023 Jun;202:76-96
Free radical biology & medicine 2023 Jun;202:76-96
LINC00493-encoded microprotein SMIM26 exerts anti-metastatic activity in renal cell carcinoma.
Meng K, Lu S, Li YY, Hu LL, Zhang J, Cao Y, Wang Y, Zhang CZ, He QY
EMBO reports 2023 Jun 5;24(6):e56282
EMBO reports 2023 Jun 5;24(6):e56282
SS-31 alleviated nociceptive responses and restored mitochondrial function in a headache mouse model via Sirt3/Pgc-1α positive feedback loop.
Shan Z, Wang Y, Qiu T, Zhou Y, Zhang Y, Hu L, Zhang L, Liang J, Ding M, Fan S, Xiao Z
The journal of headache and pain 2023 Jun 5;24(1):65
The journal of headache and pain 2023 Jun 5;24(1):65
5-HEPE reduces obesity and insulin resistance by promoting adipose tissue browning through GPR119/AMPK/PGC1α activation.
Zong Y, Wang M, Liu Y, Suo X, Fan G, Yang X
Life sciences 2023 Jun 15;323:121703
Life sciences 2023 Jun 15;323:121703
Expanding DdCBE-mediated targeting scope to aC motif preference in rat.
Qi X, Tan L, Zhang X, Jin J, Kong W, Chen W, Wang J, Dong W, Gao L, Luo L, Lu D, Gong J, Guan F, Shu W, Huang X, Zhang L, Wang S, Shen B, Ma Y
Molecular therapy. Nucleic acids 2023 Jun 13;32:1-12
Molecular therapy. Nucleic acids 2023 Jun 13;32:1-12
Toxicologic pathological mechanism of acute lung injury induced by oral administration of benzalkonium chloride in mice.
Sekijima H, Oshima T, Ueji Y, Kuno N, Kondo Y, Nomura S, Asakura T, Sakai-Sugino K, Kawano M, Komada H, Kotani H
Toxicological research 2023 Jul;39(3):409-418
Toxicological research 2023 Jul;39(3):409-418
Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis.
Radaelli E, Assenmacher CA, Verrelle J, Banerjee E, Manero F, Khiati S, Girona A, Lopez-Lluch G, Navas P, Spinazzi M
eLife 2023 Jul 28;12
eLife 2023 Jul 28;12
SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes.
Chang Y, Wang C, Zhu J, Zheng S, Sun S, Wu Y, Jiang X, Li L, Ma R, Li G
Journal of translational medicine 2023 Jul 22;21(1):494
Journal of translational medicine 2023 Jul 22;21(1):494
A proximity labeling strategy enables proteomic analysis of inter-organelle membrane contacts.
Zhou M, Kong B, Zhang X, Xiao K, Lu J, Li W, Li M, Li Z, Ji W, Hou J, Xu T
iScience 2023 Jul 21;26(7):107159
iScience 2023 Jul 21;26(7):107159
Ischemia/reperfusion-induced MiD51 upregulation recruits Drp1 to mitochondria and contributes to myocardial injury.
Gao T, Shi R, Liu Z, De D, Li R, Chen Y, Pei J, Ding M
Biochemical and biophysical research communications 2023 Jul 12;665:78-87
Biochemical and biophysical research communications 2023 Jul 12;665:78-87
Site-specific ubiquitination of VDAC1 restricts its oligomerization and mitochondrial DNA release in liver fibrosis.
Wu NN, Wang L, Wang L, Xu X, Lopaschuk GD, Zhang Y, Ren J
Experimental & molecular medicine 2023 Jan;55(1):269-280
Experimental & molecular medicine 2023 Jan;55(1):269-280
Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma.
Zheng M, Ai Z, Guo Y, Chen Y, Xie P, An W
Oncogene 2023 Jan;42(4):308-321
Oncogene 2023 Jan;42(4):308-321
Macrophage-derived exosomal miR-195a-5p impairs tubular epithelial cells mitochondria in acute kidney injury mice.
Yuan L, Yang J, Liu F, Li L, Liu J, Chen Y, Cheng J, Lu Y, Yuan Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22691
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jan;37(1):e22691
Oligomeric CHMP7 mediates three-way ER junctions and ER-mitochondria interactions.
Chu Q, Wang J, Du Y, Zhou T, Shi A, Xiong J, Ji WK, Deng L
Cell death and differentiation 2023 Jan;30(1):94-110
Cell death and differentiation 2023 Jan;30(1):94-110
Increased mitophagy protects cochlear hair cells from aminoglycoside-induced damage.
Zhang Y, Fang Q, Wang H, Qi J, Sun S, Liao M, Wu Y, Hu Y, Jiang P, Cheng C, Qian X, Tang M, Cao W, Xiang S, Zhang C, Yang J, Gao X, Ying Z, Chai R
Autophagy 2023 Jan;19(1):75-91
Autophagy 2023 Jan;19(1):75-91
STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity.
Zhu Z, Zhou X, Du H, Cloer EW, Zhang J, Mei L, Wang Y, Tan X, Hepperla AJ, Simon JM, Cook JG, Major MB, Dotti G, Liu P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jan;10(3):e2203718
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jan;10(3):e2203718
ER stress-enhanced HMGA2 plays an important role in Cr (VI)-induced glycolysis and inhibited oxidative phosphorylation by targeting the transcription of ATF4.
Luo S, Zhang C, Gao Z, Jiang L, Li Q, Shi X, Kong Y, Cao J
Chemico-biological interactions 2023 Jan 5;369:110293
Chemico-biological interactions 2023 Jan 5;369:110293
Synthesis of Novel Pentacyclic Triterpenoid Derivatives that Induce Apoptosis in Cancer Cells through a ROS-dependent, Mitochondrial-Mediated Pathway.
Cheng B, Chu X, Liu R, Ma X, Wang M, Zhang J, Jiao P, Gao Q, Ma W, Zhang Y, Zhao C, Zhou D, Xiao S
Molecular pharmaceutics 2023 Jan 2;20(1):701-710
Molecular pharmaceutics 2023 Jan 2;20(1):701-710
Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via regulation of pyruvate dehydrogenase phosphorylation.
Ikizawa T, Ikeda K, Arita M, Kitajima S, Soga T, Ichijo H, Naguro I
The Journal of biological chemistry 2023 Feb;299(2):102837
The Journal of biological chemistry 2023 Feb;299(2):102837
Novel ELAC2 Mutations in Individuals Presenting with Variably Severe Neurological Disease in the Presence or Absence of Cardiomyopathy.
Cafournet C, Zanin S, Guimier A, Hully M, Assouline Z, Barcia G, de Lonlay P, Steffann J, Munnich A, Bonnefont JP, Rötig A, Ruzzenente B, Metodiev MD
Life (Basel, Switzerland) 2023 Feb 4;13(2)
Life (Basel, Switzerland) 2023 Feb 4;13(2)
Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation.
He Y, Ji Z, Gong Y, Fan L, Xu P, Chen X, Miao J, Zhang K, Zhang W, Ma P, Zhao H, Cheng C, Wang D, Wang J, Jing N, Liu K, Zhang P, Dong B, Zhuang G, Fu Y, Xue W, Gao WQ, Zhu HH
Cell reports 2023 Feb 28;42(2):112033
Cell reports 2023 Feb 28;42(2):112033
Cytosolic Release of Mitochondrial DNA and Associated cGAS Signaling Mediates Radiation-Induced Hematopoietic Injury of Mice.
Guan H, Zhang W, Xie D, Nie Y, Chen S, Sun X, Zhao H, Liu X, Wang H, Huang X, Bai C, Huang B, Zhou P, Gao S
International journal of molecular sciences 2023 Feb 16;24(4)
International journal of molecular sciences 2023 Feb 16;24(4)
A Missense Variant in AIFM1 Caused Mitochondrial Dysfunction and Intolerance to Riboflavin Deficiency.
Zhao Y, Lin Y, Wang B, Liu F, Zhao D, Wang W, Ren H, Wang J, Xu Z, Yan C, Ji K
Neuromolecular medicine 2023 Dec;25(4):489-500
Neuromolecular medicine 2023 Dec;25(4):489-500
Zinc Overload Induces Damage to H9c2 Cardiomyocyte Through Mitochondrial Dysfunction and ROS-Mediated Mitophagy.
Yang Y, Wang P, Guo J, Ma T, Hu Y, Huang L, Xing B, He Y, Xi J
Cardiovascular toxicology 2023 Dec;23(11-12):388-405
Cardiovascular toxicology 2023 Dec;23(11-12):388-405
Deficiency of aldehyde dehydrogenase 2 aggravates ethanol-induced cytotoxicity in N2a cells via CaMKII/Drp1-mediated mitophagy.
Yan T, Chen J, Wang Y, Wang Y, Zhang Y, Zhao Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114129
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114129
Active fraction of Polyrhachis vicina (Roger) alleviated cerebral ischemia/reperfusion injury by targeting SIRT3-mediated mitophagy and angiogenesis.
Wei J, Xie J, He J, Li D, Wei D, Li Y, Li X, Fang W, Wei G, Lai K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155104
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155104
Ginsenoside Rb1 protects hippocampal neurons in depressed rats based on mitophagy-regulated astrocytic pyroptosis.
Li Y, Li J, Yang L, Ren F, Dong K, Zhao Z, Duan W, Wei W, Guo R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155083
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155083
Mitochondrial Protein SLIRP Affects Biosynthesis of Cytochrome c Oxidase Subunits in HEK293T Cells.
Baleva MV, Piunova U, Chicherin I, Vasilev R, Levitskii S, Kamenski P
International journal of molecular sciences 2023 Dec 20;25(1)
International journal of molecular sciences 2023 Dec 20;25(1)
Mitochondrion-targeted carboxymethyl chitosan hybrid nanoparticles loaded with Coenzyme Q10 protect cardiac grafts against cold ischaemia‒reperfusion injury in heart transplantation.
Yuan S, Che Y, Wang Z, Xing K, Xie X, Chen Y
Journal of translational medicine 2023 Dec 20;21(1):925
Journal of translational medicine 2023 Dec 20;21(1):925
CK1δ and CK1ε Signaling Sustains Mitochondrial Metabolism and Cell Survival in Multiple Myeloma.
Burger KL, Fernandez MR, Meads MB, Sudalagunta P, Oliveira PS, Renatino Canevarolo R, Alugubelli RR, Tungsevik A, De Avila G, Silva M, Graeter AI, Dai HA, Vincelette ND, Prabhu A, Magaletti D, Yang C, Li W, Kulkarni A, Hampton O, Koomen JM, Roush WR, Monastyrskyi A, Berglund AE, Silva AS, Cleveland JL, Shain KH
Cancer research 2023 Dec 1;83(23):3901-3919
Cancer research 2023 Dec 1;83(23):3901-3919
Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning.
Shi F, de Fatima Silva F, Liu D, Patel HU, Xu J, Zhang W, Türk C, Krüger M, Collins S
Molecular metabolism 2023 Aug;74:101753
Molecular metabolism 2023 Aug;74:101753
Huoxue Jiedu Recipe represses mitochondrial fission to alleviate submandibular gland inflammation in Sjögren's syndrome.
Xu J, Shen Z, Du Y, Zhang S, Xi Y, Zhang Y, Wang D, Zhu Y
Microbiology and immunology 2023 Aug;67(8):377-387
Microbiology and immunology 2023 Aug;67(8):377-387
Lias overexpression alleviates pulmonary injury induced by fine particulate matter in mice.
Xu G, Zhao Y, Tao Y, Xiong C, Lv M, Gao Q, Zhang F, An Z, Wu W
Environmental geochemistry and health 2023 Aug;45(8):6585-6603
Environmental geochemistry and health 2023 Aug;45(8):6585-6603
Polystyrene exacerbates cadmium-induced mitochondrial damage to lung by blocking autophagy in mice.
Tong X, Fu X, Yu G, Qu H, Zou H, Song R, Ma Y, Yuan Y, Bian J, Gu J, Liu Z
Environmental toxicology 2023 Aug;38(8):1775-1785
Environmental toxicology 2023 Aug;38(8):1775-1785
The RNA-binding protein ZC3H11A interacts with the nuclear poly(A)-binding protein PABPN1 and alters polyadenylation of viral transcripts.
Kases K, Schubert E, Hajikhezri Z, Larsson M, Devi P, Darweesh M, Andersson L, Akusjärvi G, Punga T, Younis S
The Journal of biological chemistry 2023 Aug;299(8):104959
The Journal of biological chemistry 2023 Aug;299(8):104959
Jionoside A1 alleviates ischemic stroke ischemia/reperfusion injury by promoting Nix-mediated mitophagy.
Yu X, Liu X, Mi X, Luo X, Lian Z, Tang J, Wang G
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Aug 31;69(8):237-245
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Aug 31;69(8):237-245
Flt3 Activation Mitigates Mitochondrial Fragmentation and Heart Dysfunction through Rebalanced L-OPA1 Processing by Hindering the Interaction between Acetylated p53 and PHB2 in Cardiac Remodeling.
Zhang K, Zheng Y, Bao G, Ma W, Han B, Shi H, Zhao Z
Antioxidants (Basel, Switzerland) 2023 Aug 22;12(9)
Antioxidants (Basel, Switzerland) 2023 Aug 22;12(9)
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Zhao T, Zhang J, Lei H, Meng Y, Cheng H, Zhao Y, Geng G, Mu C, Chen L, Liu Q, Luo Q, Zhang C, Long Y, Su J, Wang Y, Li Z, Sun J, Chen G, Li Y, Liao X, Shang Y, Hu G, Chen Q, Zhu Y
The EMBO journal 2023 Aug 15;42(16):e113258
The EMBO journal 2023 Aug 15;42(16):e113258
Restoration of mitochondrial function through activation of hypomodified tRNAs with pathogenic mutations associated with mitochondrial diseases.
Tomoda E, Nagao A, Shirai Y, Asano K, Suzuki T, Battersby BJ, Suzuki T
Nucleic acids research 2023 Aug 11;51(14):7563-7579
Nucleic acids research 2023 Aug 11;51(14):7563-7579
Loganin alleviated cognitive impairment in 3×Tg-AD mice through promoting mitophagy mediated by optineurin.
Zhou Y, Luo D, Shi J, Yang X, Xu W, Gao W, Guo Y, Zhao Q, Xie X, He Y, Du G, Pang X
Journal of ethnopharmacology 2023 Aug 10;312:116455
Journal of ethnopharmacology 2023 Aug 10;312:116455
Amino acids downregulate SIRT4 to detoxify ammonia through the urea cycle.
Hu SH, Feng YY, Yang YX, Ma HD, Zhou SX, Qiao YN, Zhang KH, Zhang L, Huang L, Yuan YY, Lin Y, Zhang XY, Li Y, Li HT, Zhao JY, Xu W, Zhao SM
Nature metabolism 2023 Apr;5(4):626-641
Nature metabolism 2023 Apr;5(4):626-641
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Qiu S, Zhong X, Meng X, Li S, Qian X, Lu H, Cai J, Zhang Y, Wang M, Ye Z, Zhang H, Gao P
Cell research 2023 Apr;33(4):299-311
Cell research 2023 Apr;33(4):299-311
TOM complex-independent transport pathway of myoglobin into mitochondria in C2C12 myotubes.
Koma R, Shibaguchi T, Araiso Y, Yamada T, Nonaka Y, Jue T, Masuda K
Physiological reports 2023 Apr;11(7):e15632
Physiological reports 2023 Apr;11(7):e15632
Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function.
Chen L, Zhang Q, Meng Y, Zhao T, Mu C, Fu C, Deng C, Feng J, Du S, Liu W, Geng G, Ma K, Cheng H, Liu Q, Luo Q, Zhang J, Du Z, Cao L, Wang H, Liu Y, Lin J, Chen G, Liu L, Lam SM, Shui G, Zhu Y, Chen Q
EMBO reports 2023 Apr 5;24(4):e54731
EMBO reports 2023 Apr 5;24(4):e54731
Tex2 is required for lysosomal functions at TMEM55-dependent ER membrane contact sites.
Du Y, Chang W, Gao L, Deng L, Ji WK
The Journal of cell biology 2023 Apr 3;222(4)
The Journal of cell biology 2023 Apr 3;222(4)
Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis.
Ji W, Zhang L, Ma C, Xu X, Li S, Xia H, Zhou W, Liu X
Cell reports 2023 Apr 25;42(4):112327
Cell reports 2023 Apr 25;42(4):112327
Melatonin ameliorates glyphosate- and hard water-induced renal tubular epithelial cell senescence via PINK1-Parkin-dependent mitophagy.
Zhang L, Ding F, Wu X, Wang R, Wan Y, Hu J, Zhang X, Wu Q
Ecotoxicology and environmental safety 2023 Apr 15;255:114719
Ecotoxicology and environmental safety 2023 Apr 15;255:114719
A conditional knockout rat resource of mitochondrial protein-coding genes via a DdCBE-induced premature stop codon.
Tan L, Qi X, Kong W, Jin J, Lu D, Zhang X, Wang Y, Wang S, Dong W, Shi X, Chen W, Wang J, Li K, Xie Y, Gao L, Guan F, Gao K, Li C, Wang C, Hu Z, Zhang L, Guo X, Shen B, Ma Y
Science advances 2023 Apr 14;9(15):eadf2695
Science advances 2023 Apr 14;9(15):eadf2695
Evaluation of Coenzyme Q10 (CoQ10) Deficiency and Therapy in Mouse Models of Cardiomyopathy.
Pu TT, Wu W, Liang PD, Du JC, Han SL, Deng XL, Du XJ
Journal of cardiovascular pharmacology 2023 Apr 1;81(4):259-269
Journal of cardiovascular pharmacology 2023 Apr 1;81(4):259-269
Effect of one-time high load exercise on skeletal muscle injury in rats of different genders: oxidative stress and mitochondrial responses.
Wang Y, Chen M, Gao Y, He K, Yang Z, Li Y, Zhang S, Zhao L
Acta cirurgica brasileira 2022;37(8):e370805
Acta cirurgica brasileira 2022;37(8):e370805
San-Huang-Yi-Shen Capsule Ameliorates Diabetic Kidney Disease through Inducing PINK1/Parkin-Mediated Mitophagy and Inhibiting the Activation of NLRP3 Signaling Pathway.
Li H, Wang Y, Su X, Wang Q, Zhang S, Sun W, Zhang T, Dong M, Zhang Z, Lv S
Journal of diabetes research 2022;2022:2640209
Journal of diabetes research 2022;2022:2640209
Claudin-10 overexpression suppresses human clear cell renal cell carcinoma growth and metastasis by regulating ATP5O and causing mitochondrial dysfunction.
Yang W, Zhang K, Zhang Z, Zhou J, Li L, Xu Y, Qiu J, Cai L, Gong Y, Gong K
International journal of biological sciences 2022;18(6):2329-2344
International journal of biological sciences 2022;18(6):2329-2344
B16 Membrane-Coated Vesicles for Combined Photodynamic Therapy and Immunotherapy Shift Immune Microenvironment of Melanoma.
Wang Y, Zhao Z, Liu C, Hao M, Kong C, Zhao X, Gao Y, Zhang Y, Cui W, Zhang C, Jiang J
International journal of nanomedicine 2022;17:855-868
International journal of nanomedicine 2022;17:855-868
Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction.
Guo J, Zhang L, Bu Y, Li W, Hu J, Li J
Frontiers in molecular neuroscience 2022;15:986710
Frontiers in molecular neuroscience 2022;15:986710
The expression pattern of GDF15 in human brain changes during aging and in Alzheimer's disease.
Chiariello A, Valente S, Pasquinelli G, Baracca A, Sgarbi G, Solaini G, Medici V, Fantini V, Poloni TE, Tognocchi M, Arcaro M, Galimberti D, Franceschi C, Capri M, Salvioli S, Conte M
Frontiers in aging neuroscience 2022;14:1058665
Frontiers in aging neuroscience 2022;14:1058665
Shenxiong glucose injection inhibits oxidative stress and apoptosis to ameliorate isoproterenol-induced myocardial ischemia in rats and improve the function of HUVECs exposed to CoCl(2).
Wu ZX, Chen SS, Lu DY, Xue WN, Sun J, Zheng L, Wang YL, Li C, Li YJ, Liu T
Frontiers in pharmacology 2022;13:931811
Frontiers in pharmacology 2022;13:931811
Inhibition of the PINK1-Parkin Pathway Enhances the Lethality of Sorafenib and Regorafenib in Hepatocellular Carcinoma.
Zhang S, Wang Y, Cao Y, Wu J, Zhang Z, Ren H, Xu X, Kaznacheyeva E, Li Q, Wang G
Frontiers in pharmacology 2022;13:851832
Frontiers in pharmacology 2022;13:851832
Characterization and subcellular localization of Alongshan virus proteins.
Zhao Y, Wu P, Liu L, Ma B, Pan M, Huang Y, Du N, Yu H, Sui L, Wang ZD, Hou Z, Liu Q
Frontiers in microbiology 2022;13:1000322
Frontiers in microbiology 2022;13:1000322
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model.
Yang L, Wu C, Parker E, Li Y, Dong Y, Tucker L, Brann DW, Lin HW, Zhang Q
Theranostics 2022;12(5):2205-2231
Theranostics 2022;12(5):2205-2231
Mitochondrion-Localized SND1 Promotes Mitophagy and Liver Cancer Progression Through PGAM5.
Liang S, Zhu C, Suo C, Wei H, Yu Y, Gu X, Chen L, Yuan M, Shen S, Li S, Sun L, Gao P
Frontiers in oncology 2022;12:857968
Frontiers in oncology 2022;12:857968
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
Li C, Pan Y, Tan Y, Wang Y, Sun X
Frontiers in cell and developmental biology 2022;10:896014
Frontiers in cell and developmental biology 2022;10:896014
Gefitinib facilitates PINK1/Parkin-mediated mitophagy by enhancing mitochondrial recruitment of OPTN.
Li N, Sun S, Ma G, Hou H, Ma Q, Zhang L, Zhang Z, Wang H, Ying Z
Fundamental research 2022 Sep;2(5):807-816
Fundamental research 2022 Sep;2(5):807-816
Ca(2+) channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons.
Zampese E, Wokosin DL, Gonzalez-Rodriguez P, Guzman JN, Tkatch T, Kondapalli J, Surmeier WC, D'Alessandro KB, De Stefani D, Rizzuto R, Iino M, Molkentin JD, Chandel NS, Schumacker PT, Surmeier DJ
Science advances 2022 Sep 30;8(39):eabp8701
Science advances 2022 Sep 30;8(39):eabp8701
Kaempferol impairs aerobic glycolysis against melanoma metastasis via inhibiting the mitochondrial binding of HK2 and VDAC1.
Zheng X, Pan Y, Yang G, Liu Y, Zou J, Zhao H, Yin G, Wu Y, Li X, Wei Z, Yu S, Zhao Y, Wang A, Chen W, Lu Y
European journal of pharmacology 2022 Sep 15;931:175226
European journal of pharmacology 2022 Sep 15;931:175226
Yangjing Zhongyu decoction facilitates mitochondrial activity, estrogenesis, and energy metabolism in H(2)O(2)-induced human granulosa cell line KGN.
Liu J, Shi D, Ma Q, Zhao P
Journal of ethnopharmacology 2022 Sep 15;295:115398
Journal of ethnopharmacology 2022 Sep 15;295:115398
CHCHD10 Modulates Thermogenesis of Adipocytes by Regulating Lipolysis.
Ding M, Ma YJ, Du RQ, Zhou WY, Dou X, Yang QQ, Tang Y, Qian SW, Liu Y, Pan DN, Tang QQ, Liu Y
Diabetes 2022 Sep 1;71(9):1862-1879
Diabetes 2022 Sep 1;71(9):1862-1879
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42) inhibits cell proliferation and induces apoptosis via inhibiting ALK and its downstream pathways in Karpas299 cells.
Chang X, Wang J, Bian J, Liu Z, Guo M, Li Z, Wu Y, Zhai X, Zuo D
Toxicology and applied pharmacology 2022 Sep 1;450:116156
Toxicology and applied pharmacology 2022 Sep 1;450:116156
Inhibition of High-Temperature Requirement Protein A2 Protease Activity Represses Myogenic Differentiation via UPRmt.
Sun H, Shen L, Zhang P, Lin F, Ma J, Wu Y, Yu H, Sun L
International journal of molecular sciences 2022 Oct 4;23(19)
International journal of molecular sciences 2022 Oct 4;23(19)
Protective effect of low-dose radiation on doxorubicin-induced brain injury in mice.
Gao Y, Dong J, Chen M, Wang T, Yang Z, He K, Li Y, Wang K, Jiang J, Zhang S
Archives of biochemistry and biophysics 2022 Oct 30;729:109390
Archives of biochemistry and biophysics 2022 Oct 30;729:109390
Mitophagy induced by classical swine fever virus nonstructural protein 5A promotes viral replication.
Chengcheng Z, Xiuling W, Jiahao S, Mengjiao G, Xiaorong Z, Yantao W
Virus research 2022 Oct 15;320:198886
Virus research 2022 Oct 15;320:198886
CGG repeat expansion in NOTCH2NLC causes mitochondrial dysfunction and progressive neurodegeneration in Drosophila model.
Yu J, Liufu T, Zheng Y, Xu J, Meng L, Zhang W, Yuan Y, Hong D, Charlet-Berguerand N, Wang Z, Deng J
Proceedings of the National Academy of Sciences of the United States of America 2022 Oct 11;119(41):e2208649119
Proceedings of the National Academy of Sciences of the United States of America 2022 Oct 11;119(41):e2208649119
HMGA2 mediates Cr (VI)-induced metabolic reprogramming through binding to mitochondrial D-Loop region.
Bao S, Zhang C, Luo S, Jiang L, Li Q, Kong Y, Cao J
Ecotoxicology and environmental safety 2022 Oct 1;244:114085
Ecotoxicology and environmental safety 2022 Oct 1;244:114085
GRP75 Modulates Endoplasmic Reticulum-Mitochondria Coupling and Accelerates Ca(2+)-Dependent Endothelial Cell Apoptosis in Diabetic Retinopathy.
Li Y, Li HY, Shao J, Zhu L, Xie TH, Cai J, Wang W, Cai MX, Wang ZL, Yao Y, Wei TT
Biomolecules 2022 Nov 29;12(12)
Biomolecules 2022 Nov 29;12(12)
Nuclear Receptor NR1D1 Regulates Abdominal Aortic Aneurysm Development by Targeting the Mitochondrial Tricarboxylic Acid Cycle Enzyme Aconitase-2.
Sun LY, Lyu YY, Zhang HY, Shen Z, Lin GQ, Geng N, Wang YL, Huang L, Feng ZH, Guo X, Lin N, Ding S, Yuan AC, Zhang L, Qian K, Pu J
Circulation 2022 Nov 22;146(21):1591-1609
Circulation 2022 Nov 22;146(21):1591-1609
CircRNA Samd4 induces cardiac repair after myocardial infarction by blocking mitochondria-derived ROS output.
Zheng H, Huang S, Wei G, Sun Y, Li C, Si X, Chen Y, Tang Z, Li X, Chen Y, Liao W, Liao Y, Bin J
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Nov 2;30(11):3477-3498
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Nov 2;30(11):3477-3498
Pentatricopeptide Protein PTCD2 Regulates COIII Translation in Mitochondria of the HeLa Cell Line.
Baleva MV, Chicherin I, Piunova U, Zgoda V, Patrushev MV, Levitskii S, Kamenski P
International journal of molecular sciences 2022 Nov 17;23(22)
International journal of molecular sciences 2022 Nov 17;23(22)
Mitochondrial apolipoprotein A-I binding protein alleviates atherosclerosis by regulating mitophagy and macrophage polarization.
Duan M, Chen H, Yin L, Zhu X, Novák P, Lv Y, Zhao G, Yin K
Cell communication and signaling : CCS 2022 May 7;20(1):60
Cell communication and signaling : CCS 2022 May 7;20(1):60
The MFN1 and MFN2 mitofusins promote clustering between mitochondria and peroxisomes.
Huo Y, Sun W, Shi T, Gao S, Zhuang M
Communications biology 2022 May 6;5(1):423
Communications biology 2022 May 6;5(1):423
FNIP1 regulates adipocyte browning and systemic glucose homeostasis in mice by shaping intracellular calcium dynamics.
Yin Y, Xu D, Mao Y, Xiao L, Sun Z, Liu J, Zhou D, Xu Z, Liu L, Fu T, Ding C, Guo Q, Sun W, Zhou Z, Yang L, Jia Y, Chen X, Gan Z
The Journal of experimental medicine 2022 May 2;219(5)
The Journal of experimental medicine 2022 May 2;219(5)
Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas.
Wei S, Yin D, Yu S, Lin X, Savani MR, Du K, Ku Y, Wu D, Li S, Liu H, Tian M, Chen Y, Bowie M, Hariharan S, Waitkus M, Keir ST, Sugarman ET, Deek RA, Labrie M, Khasraw M, Lu Y, Mills GB, Herlyn M, Wu K, Liu L, Wei Z, Flaherty KT, Abdullah K, Zhang G, Ashley DM
Clinical cancer research : an official journal of the American Association for Cancer Research 2022 May 13;28(10):2180-2195
Clinical cancer research : an official journal of the American Association for Cancer Research 2022 May 13;28(10):2180-2195
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
Li C, Li L, Yang M, Yang J, Zhao C, Han Y, Zhao H, Jiang N, Wei L, Xiao Y, Liu Y, Xiong X, Xi Y, Luo S, Deng F, Chen W, Yuan S, Zhu X, Xiao L, Sun L
Diabetes 2022 May 1;71(5):1034-1050
Diabetes 2022 May 1;71(5):1034-1050
Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.
Shen R, Yang K, Cheng X, Guo C, Xing X, Sun H, Liu D, Liu X, Wang D
Environmental pollution (Barking, Essex : 1987) 2022 May 1;300:118986
Environmental pollution (Barking, Essex : 1987) 2022 May 1;300:118986
Sheng Mai San ameliorated heat stress-induced liver injury via regulating energy metabolism and AMPK/Drp1-dependent autophagy process.
Zhang X, Jia Y, Yuan Z, Wen Y, Zhang Y, Ren J, Ji P, Yao W, Hua Y, Wei Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Mar;97:153920
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Mar;97:153920
Ubiquitylation of cyclin C by HACE1 regulates cisplatin-associated sensitivity in gastric cancer.
Jiang HY, Chen YL, Xu XX, Li CY, Chen Y, Li DP, Zeng XQ, Gao H
Clinical and translational medicine 2022 Mar;12(3):e770
Clinical and translational medicine 2022 Mar;12(3):e770
LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Zhao K, Huang X, Zhao W, Lu B, Yang Z
Development (Cambridge, England) 2022 Mar 15;149(6)
Development (Cambridge, England) 2022 Mar 15;149(6)
Acetaldehyde Induces Cytotoxicity via Triggering Mitochondrial Dysfunction and Overactive Mitophagy.
Yan T, Zhao Y, Jiang Z, Chen J
Molecular neurobiology 2022 Jun;59(6):3933-3946
Molecular neurobiology 2022 Jun;59(6):3933-3946
Long-term exercise pre-training attenuates Alzheimer's disease-related pathology in a transgenic rat model of Alzheimer's disease.
Yang L, Wu C, Li Y, Dong Y, Wu CY, Lee RH, Brann DW, Lin HW, Zhang Q
GeroScience 2022 Jun;44(3):1457-1477
GeroScience 2022 Jun;44(3):1457-1477
Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations.
Zhang Y, Wu J, Fu Y, Yu R, Su H, Zheng Q, Wu H, Zhou S, Wang K, Zhao J, Shen S, Xu G, Wang L, Yan C, Zou X, Lv Y, Zhang S
Oncogene 2022 Jun;41(25):3394-3408
Oncogene 2022 Jun;41(25):3394-3408
An elemental diet protects mouse salivary glands from 5-fluorouracil-induced atrophy.
Harada K, Ferdous T, Fujiwara R, Watanabe K, Mizukami Y, Mishima K
Oncology letters 2022 Jun;23(6):178
Oncology letters 2022 Jun;23(6):178
Inhibition of Drp1 ameliorates diabetic retinopathy by regulating mitochondrial homeostasis.
Zhang MY, Zhu L, Bao X, Xie TH, Cai J, Zou J, Wang W, Gu S, Li Y, Li HY, Yao Y, Wei TT
Experimental eye research 2022 Jul;220:109095
Experimental eye research 2022 Jul;220:109095
Maternal Herpesviridae infection during pregnancy alters midbrain dopaminergic signatures in adult offspring.
Burmeister AR, Gordevicius J, Paul EN, Houck C, George S, Escobar Galvis ML, Sha Q, Brundin P, Pospisilik JA, Racicot K, Brundin L
Neurobiology of disease 2022 Jul;169:105720
Neurobiology of disease 2022 Jul;169:105720
Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4.
Guo Q, Xu Z, Zhou D, Fu T, Wang W, Sun W, Xiao L, Liu L, Ding C, Yin Y, Zhou Z, Sun Z, Zhu Y, Zhou W, Jia Y, Xue J, Chen Y, Chen XW, Piao HL, Lu B, Gan Z
Science advances 2022 Jul 29;8(30):eabo0340
Science advances 2022 Jul 29;8(30):eabo0340
Disrupted mitochondrial homeostasis coupled with mitotic arrest generates antineoplastic oxidative stress.
Hao X, Bu W, Lv G, Xu L, Hou D, Wang J, Liu X, Yang T, Zhang X, Liu Q, Gong Y, Shao C
Oncogene 2022 Jan;41(3):427-443
Oncogene 2022 Jan;41(3):427-443
Extracellular vesicles derived from endothelial cells in hypoxia contribute to pulmonary artery smooth muscle cell proliferation in-vitro and pulmonary hypertension in mice.
Chen T, Sun MR, Zhou Q, Guzman AM, Ramchandran R, Chen J, Ganesh B, Raj JU
Pulmonary circulation 2022 Jan;12(1):e12014
Pulmonary circulation 2022 Jan;12(1):e12014
Dopamine receptor D1 signaling stimulates lipolysis and browning of white adipocytes.
Yu J, Zhu J, Deng J, Shen J, Du F, Wu X, Chen Y, Li M, Wen Q, Xiao Z, Zhao Y
Biochemical and biophysical research communications 2022 Jan 15;588:83-89
Biochemical and biophysical research communications 2022 Jan 15;588:83-89
Theobromine enhances the conversion of white adipocytes into beige adipocytes in a PPARγ activation-dependent manner.
Tanaka E, Mitani T, Nakashima M, Yonemoto E, Fujii H, Ashida H
The Journal of nutritional biochemistry 2022 Feb;100:108898
The Journal of nutritional biochemistry 2022 Feb;100:108898
Phenotypic and genotypic changes in obesity and type 2 diabetes of male KK mice with aging.
Iizuka Y, Kim H, Nakasatomi M, Matsumoto A, Shimizu J
Experimental animals 2022 Feb 9;71(1):71-81
Experimental animals 2022 Feb 9;71(1):71-81
Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis.
Mise S, Matsumoto A, Shimada K, Hosaka T, Takahashi M, Ichihara K, Shimizu H, Shiraishi C, Saito D, Suyama M, Yasuda T, Ide T, Izumi Y, Bamba T, Kimura-Someya T, Shirouzu M, Miyata H, Ikawa M, Nakayama KI
Nature communications 2022 Feb 28;13(1):1071
Nature communications 2022 Feb 28;13(1):1071
PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease.
Li J, Lai M, Zhang X, Li Z, Yang D, Zhao M, Wang D, Sun Z, Ehsan S, Li W, Gao H, Zhao D, Yang L
Cell death & disease 2022 Feb 18;13(2):162
Cell death & disease 2022 Feb 18;13(2):162
Protein C receptor maintains cancer stem cell properties via activating lipid synthesis in nasopharyngeal carcinoma.
Zhang P, He Q, Wang Y, Zhou G, Chen Y, Tang L, Zhang Y, Hong X, Mao Y, He Q, Yang X, Liu N, Ma J
Signal transduction and targeted therapy 2022 Feb 16;7(1):46
Signal transduction and targeted therapy 2022 Feb 16;7(1):46
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
Xu Z, Fu T, Guo Q, Zhou D, Sun W, Zhou Z, Chen X, Zhang J, Liu L, Xiao L, Yin Y, Jia Y, Pang E, Chen Y, Pan X, Fang L, Zhu MS, Fei W, Lu B, Gan Z
Nature communications 2022 Feb 16;13(1):894
Nature communications 2022 Feb 16;13(1):894
The interaction between E3 ubiquitin ligase Parkin and mitophagy receptor PHB2 links inner mitochondrial membrane ubiquitination to efficient mitophagy.
Sun S, Hou H, Ma G, Ma Q, Li N, Zhang L, Dong C, Cao M, Tam KY, Ying Z, Wang H
The Journal of biological chemistry 2022 Dec;298(12):102704
The Journal of biological chemistry 2022 Dec;298(12):102704
The Absence of Parkin Does Not Promote Dopamine or Mitochondrial Dysfunction in PolgA(D257A/D257A) Mitochondrial Mutator Mice.
Scott L, Karuppagounder SS, Neifert S, Kang BG, Wang H, Dawson VL, Dawson TM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Dec 7;42(49):9263-9277
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Dec 7;42(49):9263-9277
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
Shu Y, Hao Y, Feng J, Liu H, Li ST, Feng J, Jiang Z, Ye L, Zhou Y, Sun Y, Zhou Z, Wei H, Gao P, Zhang H, Sun L
The EMBO journal 2022 Dec 1;41(23):e111550
The EMBO journal 2022 Dec 1;41(23):e111550
Glyphosate-induced mitochondrial reactive oxygen species overproduction activates parkin-dependent mitophagy to inhibit testosterone synthesis in mouse leydig cells.
Lu L, Liu JB, Wang JQ, Lian CY, Wang ZY, Wang L
Environmental pollution (Barking, Essex : 1987) 2022 Dec 1;314:120314
Environmental pollution (Barking, Essex : 1987) 2022 Dec 1;314:120314
Calenduloside E alleviates cerebral ischemia/reperfusion injury by preserving mitochondrial function.
Li J, Bu Y, Li B, Zhang H, Guo J, Hu J, Zhang Y
Journal of molecular histology 2022 Aug;53(4):713-727
Journal of molecular histology 2022 Aug;53(4):713-727
Direct Analysis of Mitochondrial Damage Caused by Misfolded/Destabilized Proteins.
Aklima J, Onchaiya S, Saotome T, Velmurugan P, Motoichi T, Naima J, Kuroda Y, Ohta Y
International journal of molecular sciences 2022 Aug 31;23(17)
International journal of molecular sciences 2022 Aug 31;23(17)
HIF-1α mediates renal fibrosis by regulating metabolic remodeling of renal tubule epithelial cells.
Liu D, Sun H, Li K, Zhao Z, Liu Z, Zhang G, Ge Y, Zhang J, Wang D, Leng Y
Biochemical and biophysical research communications 2022 Aug 27;618:15-23
Biochemical and biophysical research communications 2022 Aug 27;618:15-23
N(6)-adenomethylation of GsdmC is essential for Lgr5(+) stem cell survival to maintain normal colonic epithelial morphogenesis.
Du J, Sarkar R, Li Y, He L, Kang W, Liao W, Liu W, Nguyen T, Zhang L, Deng Z, Dougherty U, Kupfer SS, Chen M, Pekow J, Bissonnette M, He C, Li YC
Developmental cell 2022 Aug 22;57(16):1976-1994.e8
Developmental cell 2022 Aug 22;57(16):1976-1994.e8
Ketogenesis acts as an endogenous protective programme to restrain inflammatory macrophage activation during acute pancreatitis.
Zhang L, Shi J, Du D, Niu N, Liu S, Yang X, Lu P, Shen X, Shi N, Yao L, Zhang R, Hu G, Lu G, Zhu Q, Zeng T, Liu T, Xia Q, Huang W, Xue J
EBioMedicine 2022 Apr;78:103959
EBioMedicine 2022 Apr;78:103959
Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells.
Zeng L, He J, Liu C, Zhang F, Zhang Z, Chen H, Wang Q, Ding X, Luo H
Inflammation 2022 Apr;45(2):725-738
Inflammation 2022 Apr;45(2):725-738
Role of molybdenum in material immunomodulation and periodontal wound healing: Targeting immunometabolism and mitochondrial function for macrophage modulation.
He XT, Li X, Zhang M, Tian BM, Sun LJ, Bi CS, Deng DK, Zhou H, Qu HL, Wu C, Chen FM
Biomaterials 2022 Apr;283:121439
Biomaterials 2022 Apr;283:121439
Brown adipose tissue involution associated with progressive restriction in progenitor competence.
Huang Z, Zhang Z, Moazzami Z, Heck R, Hu P, Nanda H, Ren K, Sun Z, Bartolomucci A, Gao Y, Chung D, Zhu W, Shen S, Ruan HB
Cell reports 2022 Apr 12;39(2):110575
Cell reports 2022 Apr 12;39(2):110575
Microcystin-leucine arginine (MC-LR) induces mouse ovarian inflammation by promoting granulosa cells to produce inflammatory cytokine via activation of cGAS-STING signaling.
Liu K, Zhao X, Guo M, Zhu J, Li D, Ding J, Han X, Wu J
Toxicology letters 2022 Apr 1;358:6-16
Toxicology letters 2022 Apr 1;358:6-16
Adipose-derived stem cells alleviate liver injury induced by type 1 diabetes mellitus by inhibiting mitochondrial stress and attenuating inflammation.
Hou Y, Ding W, Wu P, Liu C, Ding L, Liu J, Wang X
Stem cell research & therapy 2022 Apr 1;13(1):132
Stem cell research & therapy 2022 Apr 1;13(1):132
TGR5 Activation Ameliorates Mitochondrial Homeostasis via Regulating the PKCδ/Drp1-HK2 Signaling in Diabetic Retinopathy.
Zhang MY, Zhu L, Zheng X, Xie TH, Wang W, Zou J, Li Y, Li HY, Cai J, Gu S, Yao Y, Wei TT
Frontiers in cell and developmental biology 2021;9:759421
Frontiers in cell and developmental biology 2021;9:759421
PINK1 Alleviates Cognitive Impairments via Attenuating Pathological Tau Aggregation in a Mouse Model of Tauopathy.
Jiang XJ, Wu YQ, Ma R, Chang YM, Li LL, Zhu JH, Liu GP, Li G
Frontiers in cell and developmental biology 2021;9:736267
Frontiers in cell and developmental biology 2021;9:736267
Transcription-Based Multidimensional Regulation of Fatty Acid Metabolism by HIF1α in Renal Tubules.
Li W, Duan A, Xing Y, Xu L, Yang J
Frontiers in cell and developmental biology 2021;9:690079
Frontiers in cell and developmental biology 2021;9:690079
Phosphorylation of Dynamin-Related Protein 1 (DRP1) Regulates Mitochondrial Dynamics and Skeletal Muscle Wasting in Cancer Cachexia.
Mao X, Gu Y, Sui X, Shen L, Han J, Wang H, Xi Q, Zhuang Q, Meng Q, Wu G
Frontiers in cell and developmental biology 2021;9:673618
Frontiers in cell and developmental biology 2021;9:673618
Mutations in RNA Methyltransferase Gene NSUN5 Confer High Risk of Outflow Tract Malformation.
Wang Y, Jiang T, Xu J, Gu Y, Zhou Y, Lin Y, Wu Y, Li W, Wang C, Shen B, Mo X, Wang X, Zhou B, Ding C, Hu Z
Frontiers in cell and developmental biology 2021;9:623394
Frontiers in cell and developmental biology 2021;9:623394
Samm50 Promotes Hypertrophy by Regulating Pink1-Dependent Mitophagy Signaling in Neonatal Cardiomyocytes.
Xu R, Kang L, Wei S, Yang C, Fu Y, Ding Z, Zou Y
Frontiers in cardiovascular medicine 2021;8:748156
Frontiers in cardiovascular medicine 2021;8:748156
Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy.
Zhao R, Wang B, Wang D, Wu B, Ji P, Tan D
Oxidative medicine and cellular longevity 2021;2021:6675264
Oxidative medicine and cellular longevity 2021;2021:6675264
Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke.
Yang DQ, Zuo QN, Wang T, Xu D, Lian L, Gao LJ, Wan C, Chen L, Wen FQ, Shen YC
Oxidative medicine and cellular longevity 2021;2021:6644238
Oxidative medicine and cellular longevity 2021;2021:6644238
Tubeimoside I Ameliorates Myocardial Ischemia-Reperfusion Injury through SIRT3-Dependent Regulation of Oxidative Stress and Apoptosis.
Lv D, Luo M, Cheng Z, Wang R, Yang X, Guo Y, Huang L, Li X, Huang B, Shen J, Luo S, Yan J
Oxidative medicine and cellular longevity 2021;2021:5577019
Oxidative medicine and cellular longevity 2021;2021:5577019
Inhibition of α-Synuclein Accumulation Improves Neuronal Apoptosis and Delayed Postoperative Cognitive Recovery in Aged Mice.
Li Y, Yuan Y, Li Y, Han D, Liu T, Yang N, Mi X, Hong J, Liu K, Song Y, He J, Zhou Y, Han Y, Shi C, Yu S, Zou P, Guo X, Li Z
Oxidative medicine and cellular longevity 2021;2021:5572899
Oxidative medicine and cellular longevity 2021;2021:5572899
miRNA-27a Transcription Activated by c-Fos Regulates Myocardial Ischemia-Reperfusion Injury by Targeting ATAD3a.
Bao Y, Qiao Y, Yu H, Zhang Z, Yang H, Xin X, Chen Y, Guo Y, Wu N, Jia D
Oxidative medicine and cellular longevity 2021;2021:2514947
Oxidative medicine and cellular longevity 2021;2021:2514947
Inhibition of PI3K/AKT signaling via ROS regulation is involved in Rhein-induced apoptosis and enhancement of oxaliplatin sensitivity in pancreatic cancer cells.
Liu Y, Shi C, He Z, Zhu F, Wang M, He R, Zhao C, Shi X, Zhou M, Pan S, Gao Y, Li X, Qin R
International journal of biological sciences 2021;17(2):589-602
International journal of biological sciences 2021;17(2):589-602
High-Fat Diet-Induced Mitochondrial Dysfunction Promotes Genioglossus Injury - A Potential Mechanism for Obstructive Sleep Apnea with Obesity.
Chen Q, Han X, Chen M, Zhao B, Sun B, Sun L, Zhang W, Yu L, Liu Y
Nature and science of sleep 2021;13:2203-2219
Nature and science of sleep 2021;13:2203-2219
Sympathetic Denervation Ameliorates Renal Fibrosis via Inhibition of Cellular Senescence.
Li Q, Deng Y, Liu L, Zhang C, Cai Y, Zhang T, Han M, Xu G
Frontiers in immunology 2021;12:823935
Frontiers in immunology 2021;12:823935
Cordycepin Decreases Ischemia/Reperfusion Injury in Diabetic Hearts via Upregulating AMPK/Mfn2-dependent Mitochondrial Fusion.
Yu H, Hong X, Liu L, Wu Y, Xie X, Fang G, Zhi S
Frontiers in pharmacology 2021;12:754005
Frontiers in pharmacology 2021;12:754005
Empagliflozin Induces White Adipocyte Browning and Modulates Mitochondrial Dynamics in KK Cg-Ay/J Mice and Mouse Adipocytes.
Xu L, Xu C, Liu X, Li X, Li T, Yu X, Xue M, Yang J, Kosmas CE, Moris D, Sanchis-Gomar F, Yoshida N, Berger NA, Aronow WS, Sun B, Chen L
Frontiers in physiology 2021;12:745058
Frontiers in physiology 2021;12:745058
Antioxidant activity of mesenchymal stem cell-derived extracellular vesicles restores hippocampal neurons following seizure damage.
Luo Q, Xian P, Wang T, Wu S, Sun T, Wang W, Wang B, Yang H, Yang Y, Wang H, Liu W, Long Q
Theranostics 2021;11(12):5986-6005
Theranostics 2021;11(12):5986-6005
Gastrodin protects against high glucose-induced cardiomyocyte toxicity via GSK-3β-mediated nuclear translocation of Nrf2.
Dong Z, Bian L, Wang YL, Sun LM
Human & experimental toxicology 2021 Sep;40(9):1584-1597
Human & experimental toxicology 2021 Sep;40(9):1584-1597
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Mitochondria transplantation protects traumatic brain injury via promoting neuronal survival and astrocytic BDNF.
Zhao J, Qu D, Xi Z, Huan Y, Zhang K, Yu C, Yang D, Kang J, Lin W, Wu S, Wang Y
Translational research : the journal of laboratory and clinical medicine 2021 Sep;235:102-114
Translational research : the journal of laboratory and clinical medicine 2021 Sep;235:102-114
PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma.
Wang B, Yin X, Gan W, Pan F, Li S, Xiang Z, Han X, Li D
Autophagy 2021 Sep;17(9):2475-2493
Autophagy 2021 Sep;17(9):2475-2493
3D-printing magnesium-polycaprolactone loaded with melatonin inhibits the development of osteosarcoma by regulating cell-in-cell structures.
Zhang W, Zhao W, Li Q, Zhao D, Qu J, Yuan Z, Cheng Z, Zhu X, Zhuang X, Zhang Z
Journal of nanobiotechnology 2021 Sep 4;19(1):263
Journal of nanobiotechnology 2021 Sep 4;19(1):263
Sigma-1 receptor regulates mitophagy in dopaminergic neurons and contributes to dopaminergic protection.
Wang M, Wan C, He T, Han C, Zhu K, Waddington JL, Zhen X
Neuropharmacology 2021 Sep 15;196:108360
Neuropharmacology 2021 Sep 15;196:108360
A requirement for autophagy in HMGA2-induced metabolic reprogramming to support Cd-induced migration.
Hasenbilige, Mei J, Dlamini MB, Gao Z, Jiang L, Li Q, Geng C, Shi X, Liu Y, Kong Y, Cao J
Toxicology 2021 Oct;462:152928
Toxicology 2021 Oct;462:152928
Load-matched acute and chronic exercise induce changes in mitochondrial biogenesis and metabolic markers.
Rodrigues NA, Gobatto CA, Forte LDM, Sousa FAB, Torsoni AS, Fante T, Manchado-Gobatto FB
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2021 Oct;46(10):1196-1206
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2021 Oct;46(10):1196-1206
Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca(2+) homeostasis.
Zhong Y, Jin C, Han J, Zhu J, Liu Q, Sun D, Xia X, Peng X
Cell biology and toxicology 2021 Oct;37(5):795-809
Cell biology and toxicology 2021 Oct;37(5):795-809
Chaperone-mediated autophagy controls the turnover of E3 ubiquitin ligase MARCHF5 and regulates mitochondrial dynamics.
Nie T, Tao K, Zhu L, Huang L, Hu S, Yang R, Xu P, Mao Z, Yang Q
Autophagy 2021 Oct;17(10):2923-2938
Autophagy 2021 Oct;17(10):2923-2938
Influence of psychostimulants and opioids on epigenetic modification of class III histone deacetylase (HDAC)-sirtuins in glial cells.
Sivalingam K, Doke M, Khan MA, Samikkannu T
Scientific reports 2021 Oct 29;11(1):21335
Scientific reports 2021 Oct 29;11(1):21335
EF24 exerts cytotoxicity against NSCLC via inducing ROS accumulation.
Chang M, Shang M, Yuan F, Guo W, Wang C
Cancer cell international 2021 Oct 12;21(1):531
Cancer cell international 2021 Oct 12;21(1):531
Kir6.2 is essential to maintain neurite features by modulating PM20D1-reduced mitochondrial ATP generation.
Song N, Fang Y, Zhu H, Liu J, Jiang S, Sun S, Xu R, Ding J, Hu G, Lu M
Redox biology 2021 Nov;47:102168
Redox biology 2021 Nov;47:102168
Methionine synthase supports tumour tetrahydrofolate pools.
Ghergurovich JM, Xu X, Wang JZ, Yang L, Ryseck RP, Wang L, Rabinowitz JD
Nature metabolism 2021 Nov;3(11):1512-1520
Nature metabolism 2021 Nov;3(11):1512-1520
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
Huang T, Xu T, Wang Y, Zhou Y, Yu D, Wang Z, He L, Chen Z, Zhang Y, Davidson D, Dai Y, Hang C, Liu X, Yan C
Autophagy 2021 Nov;17(11):3592-3606
Autophagy 2021 Nov;17(11):3592-3606
trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway.
Hirata Y, Takahashi M, Yamada Y, Matsui R, Inoue A, Ashida R, Noguchi T, Matsuzawa A
Scientific reports 2021 May 14;11(1):10350
Scientific reports 2021 May 14;11(1):10350
Preservation of mitochondrial homeostasis is responsible for the ameliorative effects of Suhuang antitussive capsule on non-resolving inflammation via inhibition of NF-κB signaling and NLRP3 inflammasome activation.
Qin W, Tong X, Liang R, Tang K, Wu X, Jia Y, Tan N
Journal of ethnopharmacology 2021 May 10;271:113827
Journal of ethnopharmacology 2021 May 10;271:113827
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Shi M, Huang XY, Ren XY, Wei XY, Ma Y, Lin ZZ, Liu DT, Song L, Zhao TJ, Li G, Yao L, Zhu M, Zhang C, Xie C, Wu Y, Wu HM, Fan LP, Ou J, Zhan YH, Lin SY, Lin SC
Nature cell biology 2021 Mar;23(3):268-277
Nature cell biology 2021 Mar;23(3):268-277
AMPK-dependent and -independent coordination of mitochondrial function and muscle fiber type by FNIP1.
Xiao L, Liu J, Sun Z, Yin Y, Mao Y, Xu D, Liu L, Xu Z, Guo Q, Ding C, Sun W, Yang L, Zhou Z, Zhou D, Fu T, Zhou W, Zhu Y, Chen XW, Li JZ, Chen S, Xie X, Gan Z
PLoS genetics 2021 Mar;17(3):e1009488
PLoS genetics 2021 Mar;17(3):e1009488
MiR-133a-3p relieves the oxidative stress induced trophoblast cell apoptosis through the BACH1/Nrf2/HO-1 signaling pathway.
Guo H, Wang Y, Jia W, Liu L
Physiological research 2021 Mar 17;70(1):67-78
Physiological research 2021 Mar 17;70(1):67-78
Empagliflozin alleviates ethanol-induced cardiomyocyte injury through inhibition of mitochondrial apoptosis via a SIRT1/PTEN/Akt pathway.
Tian G, Yu Y, Deng H, Yang L, Shi X, Yu B
Clinical and experimental pharmacology & physiology 2021 Jun;48(6):837-845
Clinical and experimental pharmacology & physiology 2021 Jun;48(6):837-845
ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.
Lin BC, Phung TH, Higgins NR, Greenslade JE, Prado MA, Finley D, Karbowski M, Polster BM, Monteiro MJ
Human molecular genetics 2021 Jun 17;30(13):1230-1246
Human molecular genetics 2021 Jun 17;30(13):1230-1246
Enzymatic activation of pyruvate kinase increases cytosolic oxaloacetate to inhibit the Warburg effect.
Wiese EK, Hitosugi S, Loa ST, Sreedhar A, Andres-Beck LG, Kurmi K, Pang YP, Karnitz LM, Gonsalves WI, Hitosugi T
Nature metabolism 2021 Jul;3(7):954-968
Nature metabolism 2021 Jul;3(7):954-968
S100B/RAGE/Ceramide signaling pathway is involved in sepsis-associated encephalopathy.
Zhang L, Jiang Y, Deng S, Mo Y, Huang Y, Li W, Ge C, Ren X, Zhang H, Zhang X, Peng Q, Liu Z, Huang L, Zhou F, Ai Y
Life sciences 2021 Jul 15;277:119490
Life sciences 2021 Jul 15;277:119490
miR-34a-5p regulates PINK1-mediated mitophagy via multiple modes.
Tai Y, Pu M, Yuan L, Guo H, Qiao J, Lu H, Wang G, Chen J, Qi X, Tao Z, Ren J
Life sciences 2021 Jul 1;276:119415
Life sciences 2021 Jul 1;276:119415
Selenium Deficiency-Induced Damage and Altered Expression of Mitochondrial Biogenesis Markers in the Kidneys of Mice.
Lai H, Nie T, Zhang Y, Chen Y, Tao J, Lin T, Ge T, Li F, Li H
Biological trace element research 2021 Jan;199(1):185-196
Biological trace element research 2021 Jan;199(1):185-196
OMA1 reprograms metabolism under hypoxia to promote colorectal cancer development.
Wu Z, Zuo M, Zeng L, Cui K, Liu B, Yan C, Chen L, Dong J, Shangguan F, Hu W, He H, Lu B, Song Z
EMBO reports 2021 Jan 7;22(1):e50827
EMBO reports 2021 Jan 7;22(1):e50827
Neuroprotection against cerebral ischemia/reperfusion by dietary phytochemical extracts from Tibetan turnip (Brassica rapa L.).
Hua H, Zhang W, Li J, Li J, Liu C, Guo Y, Cheng Y, Pi F, Xie Y, Yao W, Gao Y, Qian H
Journal of ethnopharmacology 2021 Jan 30;265:113410
Journal of ethnopharmacology 2021 Jan 30;265:113410
The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling.
Li S, Kuang M, Chen L, Li Y, Liu S, Du H, Cao L, You F
Cell reports 2021 Jan 19;34(3):108631
Cell reports 2021 Jan 19;34(3):108631
Bioactivation of clozapine by mitochondria of the murine heart: Possible cause of cardiotoxicity.
Arzuk E, Karakuş F, Orhan H
Toxicology 2021 Jan 15;447:152628
Toxicology 2021 Jan 15;447:152628
MiR-133a-3p relieves the oxidative stress induced trophoblast cell apoptosis through the BACH1/Nrf2/HO-1 signaling pathway.
Guo H, Wang Y, Jia W, Liu L
Physiological research 2021 Jan 14;70(1)
Physiological research 2021 Jan 14;70(1)
Remote Ischemic Postconditioning Inhibits Hippocampal Neuronal Apoptosis and Mitophagy After Cardiopulmonary Resuscitation in Rats.
Xie B, Gao X, Huang Y, Zhang Y, Zhu S
Shock (Augusta, Ga.) 2021 Jan 1;55(1):74-82
Shock (Augusta, Ga.) 2021 Jan 1;55(1):74-82
Involvement of miR-27a-3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress.
Wu L, Wang Q, Guo F, Ma X, Wang J, Zhao Y, Yan Y, Qin G
Journal of cellular physiology 2021 Feb;236(2):1454-1468
Journal of cellular physiology 2021 Feb;236(2):1454-1468
p53 induces ARTS to promote mitochondrial apoptosis.
Hao Q, Chen J, Liao J, Huang Y, Gan Y, Larisch S, Zeng SX, Lu H, Zhou X
Cell death & disease 2021 Feb 24;12(2):204
Cell death & disease 2021 Feb 24;12(2):204
Lobetyolin inhibits the proliferation of breast cancer cells via ASCT2 down-regulation-induced apoptosis.
Chen Y, Tian Y, Jin G, Cui Z, Guo W, Zhang X, Liu X
Human & experimental toxicology 2021 Dec;40(12):2074-2086
Human & experimental toxicology 2021 Dec;40(12):2074-2086
UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesothelioma.
Liu F, Pan R, Ding H, Gu L, Yang Y, Li C, Xu Y, Hu R, Chen H, Zhang X, Nie Y
Molecular oncology 2021 Dec;15(12):3738-3752
Molecular oncology 2021 Dec;15(12):3738-3752
SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species.
Moustaqil M, Ollivier E, Chiu HP, Van Tol S, Rudolffi-Soto P, Stevens C, Bhumkar A, Hunter DJB, Freiberg AN, Jacques D, Lee B, Sierecki E, Gambin Y
Emerging microbes & infections 2021 Dec;10(1):178-195
Emerging microbes & infections 2021 Dec;10(1):178-195
USP30-AS1 contributes to mitochondrial quality control in glioblastoma cells.
Wang N, Li J, Xin Q, Xu N
Biochemical and biophysical research communications 2021 Dec 3;581:31-37
Biochemical and biophysical research communications 2021 Dec 3;581:31-37
Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis.
Zou Q, Yang L, Shi R, Qi Y, Zhang X, Qi H
iScience 2021 Dec 17;24(12):103396
iScience 2021 Dec 17;24(12):103396
A novel protoapigenone analog RY10-4 induces apoptosis of breast cancer cells by exacerbating mitochondrial Ca(2+) influx through mitochondrial calcium uniporter.
Xue P, Chen Q, Ren X, Liu D, Yang X
Toxicology and applied pharmacology 2021 Dec 15;433:115776
Toxicology and applied pharmacology 2021 Dec 15;433:115776
Docosahexaenoic acid promotes the formation of autophagosomes in MCF-7 breast cancer cells through oxidative stress-induced growth inhibitor 1 mediated activation of AMPK/mTOR pathway.
Tsai CH, Lii CK, Wang TS, Liu KL, Chen HW, Huang CS, Li CC
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Aug;154:112318
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Aug;154:112318
Cypermethrin induces Sertoli cell apoptosis through mitochondrial pathway associated with calcium.
Wang HX, Zhang R, Li Z, Wang LS, Yu Y, Wang Q, Ding Z, Zhang JP, Zhang MR, Xu LC
Toxicology research 2021 Aug;10(4):742-750
Toxicology research 2021 Aug;10(4):742-750
SESN2 protects against denervated muscle atrophy through unfolded protein response and mitophagy.
Yang X, Xue P, Yuan M, Xu X, Wang C, Li W, Machens HG, Chen Z
Cell death & disease 2021 Aug 24;12(9):805
Cell death & disease 2021 Aug 24;12(9):805
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
Lei Y, Zhang X, Xu Q, Liu S, Li C, Jiang H, Lin H, Kong E, Liu J, Qi S, Li H, Xu W, Lu K
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
Protective autophagy attenuates soft substrate-induced apoptosis through ROS/JNK signaling pathway in breast cancer cells.
Chen Y, Li P, Peng Y, Xie X, Zhang Y, Jiang Y, Li T, Qin X, Li S, Yang H, Wu C, Zheng C, Zhu J, You F, Liu Y
Free radical biology & medicine 2021 Aug 20;172:590-603
Free radical biology & medicine 2021 Aug 20;172:590-603
Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells.
Xiaoli F, Yaqing Z, Ruhui L, Xuan L, Aijie C, Yanli Z, Chen H, Lili C, Longquan S
Journal of hazardous materials 2021 Aug 15;416:126158
Journal of hazardous materials 2021 Aug 15;416:126158
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions.
Du Y, Wang J, Xiong J, Fang N, Ji WK
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Molecular biology of the cell 2021 Aug 1;32(16):1474-1486
Bioactive compound from the Tibetan turnip (Brassica rapa L.) elicited anti-hypoxia effects in OGD/R-injured HT22 cells by activating the PI3K/AKT pathway.
Hua H, Zhu H, Liu C, Zhang W, Li J, Hu B, Guo Y, Cheng Y, Pi F, Xie Y, Yao W, Qian H
Food & function 2021 Apr 7;12(7):2901-2913
Food & function 2021 Apr 7;12(7):2901-2913
Raman Spectroscopic Assessment of Myocardial Viability in Langendorff-Perfused Ischemic Rat Hearts.
Ikemoto K, Hashimoto K, Harada Y, Kumamoto Y, Hayakawa M, Mochizuki K, Matsuo K, Yashiro K, Yaku H, Takamatsu T, Tanaka H
Acta histochemica et cytochemica 2021 Apr 28;54(2):65-72
Acta histochemica et cytochemica 2021 Apr 28;54(2):65-72
The positive regulation loop between NRF1 and NONO-TFE3 fusion promotes phase separation and aggregation of NONO-TFE3 in NONO-TFE3 tRCC.
Wang B, Gan W, Han X, Liu N, Ma T, Li D
International journal of biological macromolecules 2021 Apr 15;176:437-447
International journal of biological macromolecules 2021 Apr 15;176:437-447
RGS12 is required for the maintenance of mitochondrial function during skeletal development.
Yuan G, Yang S, Liu M, Yang S
Cell discovery 2020;6:59
Cell discovery 2020;6:59
Melatonin Protects Goat Spermatogonial Stem Cells against Oxidative Damage during Cryopreservation by Improving Antioxidant Capacity and Inhibiting Mitochondrial Apoptosis Pathway.
Feng TY, Li Q, Ren F, Xi HM, Lv DL, Li Y, Hu JH
Oxidative medicine and cellular longevity 2020;2020:5954635
Oxidative medicine and cellular longevity 2020;2020:5954635
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Deng X, Liu J, Liu L, Sun X, Huang J, Dong J
International journal of biological sciences 2020;16(8):1403-1416
International journal of biological sciences 2020;16(8):1403-1416
Hydrogen Sulfide Overproduction Is Involved in Acute Ischemic Cerebral Injury Under Hyperhomocysteinemia.
Ji Y, Li Y, Zhao Z, Li P, Xie Y
Frontiers in neuroscience 2020;14:582851
Frontiers in neuroscience 2020;14:582851
Lysophosphatidic Acid Induces Apoptosis of PC12 Cells Through LPA1 Receptor/LPA2 Receptor/MAPK Signaling Pathway.
Zhang J, Li Y, Wang C, Wang Y, Zhang Y, Huang L, Zhang Z
Frontiers in molecular neuroscience 2020;13:16
Frontiers in molecular neuroscience 2020;13:16
Perindopril Improves Cardiac Function by Enhancing the Expression of SIRT3 and PGC-1α in a Rat Model of Isoproterenol-Induced Cardiomyopathy.
Zhu Z, Li H, Chen W, Cui Y, Huang A, Qi X
Frontiers in pharmacology 2020;11:94
Frontiers in pharmacology 2020;11:94
Denervation drives skeletal muscle atrophy and induces mitochondrial dysfunction, mitophagy and apoptosis via miR-142a-5p/MFN1 axis.
Yang X, Xue P, Chen H, Yuan M, Kang Y, Duscher D, Machens HG, Chen Z
Theranostics 2020;10(3):1415-1432
Theranostics 2020;10(3):1415-1432
DW14006 as a Direct AMPKα Activator Ameliorates Diabetic Peripheral Neuropathy in Mice.
Xu X, Wang W, Wang Z, Lv J, Xu X, Xu J, Yang J, Zhu X, Lu Y, Duan W, Huang X, Wang J, Zhou J, Shen X
Diabetes 2020 Sep;69(9):1974-1988
Diabetes 2020 Sep;69(9):1974-1988
Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy.
Wu H, Wei H, Zhang D, Sehgal SA, Zhang D, Wang X, Qin Y, Liu L, Chen Q
Redox biology 2020 Sep;36:101661
Redox biology 2020 Sep;36:101661
Mitochondrial superoxide contributes to oxidative stress exacerbated by DNA damage response in RAD51-depleted ovarian cancer cells.
Xu L, Wu T, Lu S, Hao X, Qin J, Wang J, Zhang X, Liu Q, Kong B, Gong Y, Liu Z, Shao C
Redox biology 2020 Sep;36:101604
Redox biology 2020 Sep;36:101604
Dependence of PINK1 accumulation on mitochondrial redox system.
Gao F, Zhang Y, Hou X, Tao Z, Ren H, Wang G
Aging cell 2020 Sep;19(9):e13211
Aging cell 2020 Sep;19(9):e13211
Muscone suppresses inflammatory responses and neuronal damage in a rat model of cervical spondylotic myelopathy by regulating Drp1-dependent mitochondrial fission.
Zhou LY, Yao M, Tian ZR, Liu SF, Song YJ, Ye J, Li G, Sun YL, Cui XJ, Wang YJ
Journal of neurochemistry 2020 Sep;155(2):154-176
Journal of neurochemistry 2020 Sep;155(2):154-176
Mcl-1-mediated mitochondrial fission protects against stress but impairs cardiac adaptation to exercise.
Moyzis AG, Lally NS, Liang W, Leon LJ, Najor RH, Orogo AM, Gustafsson ÅB
Journal of molecular and cellular cardiology 2020 Sep;146:109-120
Journal of molecular and cellular cardiology 2020 Sep;146:109-120
Inhibition of miR-181a-5p reduces astrocyte and microglia activation and oxidative stress by activating SIRT1 in immature rats with epilepsy.
Kong H, Wang H, Zhuo Z, Li Z, Tian P, Wu J, Liu J, Chen Z, Zhang J, Luo Q
Laboratory investigation; a journal of technical methods and pathology 2020 Sep;100(9):1223-1237
Laboratory investigation; a journal of technical methods and pathology 2020 Sep;100(9):1223-1237
Neuroprotective Effect of Piracetam against Cocaine-Induced Neuro Epigenetic Modification of DNA Methylation in Astrocytes.
Sivalingam K, Samikkannu T
Brain sciences 2020 Sep 5;10(9)
Brain sciences 2020 Sep 5;10(9)
Immunoprecipitation of Acetyl-lysine And Western Blotting of Long-chain acyl-CoA Dehydrogenases and Beta-hydroxyacyl-CoA Dehydrogenase in Palmitic Acid Treated Human Renal Tubular Epithelial Cells.
Lv T, Zhu S, Ma Y, Feng H, Wan Q
Bio-protocol 2020 Sep 20;10(18):e3765
Bio-protocol 2020 Sep 20;10(18):e3765
DsbA-L mediated renal tubulointerstitial fibrosis in UUO mice.
Li X, Pan J, Li H, Li G, Liu X, Liu B, He Z, Peng Z, Zhang H, Li Y, Xiang X, Chai X, Yuan Y, Zheng P, Liu F, Zhang D
Nature communications 2020 Sep 18;11(1):4467
Nature communications 2020 Sep 18;11(1):4467
Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras-Driven Tumor Growth or Metastasis.
Ghergurovich JM, Esposito M, Chen Z, Wang JZ, Bhatt V, Lan T, White E, Kang Y, Guo JY, Rabinowitz JD
Cancer research 2020 Sep 15;80(18):3820-3829
Cancer research 2020 Sep 15;80(18):3820-3829
1-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)-3-(2-(dimethylamino)ethyl)imidazolidin-2-one (ZX-42), a novel ALK inhibitor, induces apoptosis and protective autophagy in H2228 cells.
Wang L, Xu X, Liu T, Wang J, Shen J, Guo M, Wu Y, Zhai X, Zuo D
The Journal of pharmacy and pharmacology 2020 Oct;72(10):1370-1382
The Journal of pharmacy and pharmacology 2020 Oct;72(10):1370-1382
V-ATPase blockade reduces renal gluconeogenesis and improves insulin secretion in type 2 diabetic rats.
Hirao J, Tojo A, Hatakeyama S, Satonaka H, Ishimitsu T
Hypertension research : official journal of the Japanese Society of Hypertension 2020 Oct;43(10):1079-1088
Hypertension research : official journal of the Japanese Society of Hypertension 2020 Oct;43(10):1079-1088
OPA1 and MICOS Regulate mitochondrial crista dynamics and formation.
Hu C, Shu L, Huang X, Yu J, Li L, Gong L, Yang M, Wu Z, Gao Z, Zhao Y, Chen L, Song Z
Cell death & disease 2020 Oct 31;11(10):940
Cell death & disease 2020 Oct 31;11(10):940
Melatonin suppresses ER stress-dependent proapoptotic effects via AMPK in bone mesenchymal stem cells during mitochondrial oxidative damage.
Fan C, Feng J, Tang C, Zhang Z, Feng Y, Duan W, Zhai M, Yan Z, Zhu L, Feng L, Zhu H, Luo E
Stem cell research & therapy 2020 Oct 15;11(1):442
Stem cell research & therapy 2020 Oct 15;11(1):442
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
Jiang N, Zhao H, Han Y, Li L, Xiong S, Zeng L, Xiao Y, Wei L, Xiong X, Gao P, Yang M, Liu Y, Sun L
Cell proliferation 2020 Nov;53(11):e12909
Cell proliferation 2020 Nov;53(11):e12909
Berberine protects against diabetic retinopathy by inhibiting cell apoptosis via deactivation of the NF‑κB signaling pathway.
Zhai J, Li Z, Zhang H, Ma L, Ma Z, Zhang Y, Zou J, Li M, Ma L, Wang X, Li X
Molecular medicine reports 2020 Nov;22(5):4227-4235
Molecular medicine reports 2020 Nov;22(5):4227-4235
Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
Liu YC, Wang HL, Huang YZ, Weng YH, Chen RS, Tsai WC, Yeh TH, Lu CS, Chen YL, Lin YW, Chen YJ, Hsu CC, Chiu CH, Chiu CC
Biochemical pharmacology 2020 May;175:113919
Biochemical pharmacology 2020 May;175:113919
Inhibition of thioredoxin reductase 1 correlates with platinum-based chemotherapeutic induced tissue injury.
Cheng P, Liu H, Li Y, Pi P, Jiang Y, Zang S, Li X, Fu A, Ren X, Xu J, Holmgren A, Lu J
Biochemical pharmacology 2020 May;175:113873
Biochemical pharmacology 2020 May;175:113873
Echinacoside attenuates inflammatory response in a rat model of cervical spondylotic myelopathy via inhibition of excessive mitochondrial fission.
Zhou L, Yao M, Tian Z, Song Y, Sun Y, Ye J, Li G, Sng KS, Xu L, Cui X, Wang Y
Free radical biology & medicine 2020 May 20;152:697-714
Free radical biology & medicine 2020 May 20;152:697-714
Overexpression of endogenous lipoic acid synthase attenuates pulmonary fibrosis induced by crystalline silica in mice.
Zhao Y, Xu G, Li H, Chang M, Guan Y, Li Y, Wu W, Yao S
Toxicology letters 2020 May 1;323:57-66
Toxicology letters 2020 May 1;323:57-66
The mitochondria-targeted anti-oxidant MitoQ protects against intervertebral disc degeneration by ameliorating mitochondrial dysfunction and redox imbalance.
Kang L, Liu S, Li J, Tian Y, Xue Y, Liu X
Cell proliferation 2020 Mar;53(3):e12779
Cell proliferation 2020 Mar;53(3):e12779
FSH prevents porcine granulosa cells from hypoxia-induced apoptosis via activating mitophagy through the HIF-1α-PINK1-Parkin pathway.
Li C, Zhou J, Liu Z, Zhou J, Yao W, Tao J, Shen M, Liu H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):3631-3645
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):3631-3645
Dynamic PGAM5 multimers dephosphorylate BCL-xL or FUNDC1 to regulate mitochondrial and cellular fate.
Ma K, Zhang Z, Chang R, Cheng H, Mu C, Zhao T, Chen L, Zhang C, Luo Q, Lin J, Zhu Y, Chen Q
Cell death and differentiation 2020 Mar;27(3):1036-1051
Cell death and differentiation 2020 Mar;27(3):1036-1051
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis.
Li ST, Huang D, Shen S, Cai Y, Xing S, Wu G, Jiang Z, Hao Y, Yuan M, Wang N, Zhu L, Yan R, Yang D, Wang L, Liu Z, Hu X, Zhou R, Qu K, Li A, Duan X, Zhang H, Gao P
Nature metabolism 2020 Mar;2(3):256-269
Nature metabolism 2020 Mar;2(3):256-269
Quantitative Mitochondrial Proteomics Reveals ANXA7 as a Crucial Factor in Mitophagy.
Meng K, Lu S, Yan X, Sun Y, Gao J, Wang Y, Yin X, Sun Z, He QY
Journal of proteome research 2020 Mar 6;19(3):1275-1284
Journal of proteome research 2020 Mar 6;19(3):1275-1284
Drp1, a potential therapeutic target for Parkinson's disease, is involved in olfactory bulb pathological alteration in the Rotenone-induced rat model.
Zhang X, Huang W, Shao Q, Yang Y, Xu Z, Chen J, Zhang X, Ge X
Toxicology letters 2020 Jun 1;325:1-13
Toxicology letters 2020 Jun 1;325:1-13
Prenatal High-Salt Diet-Induced Metabolic Disorders via Decreasing Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1α in Adult Male Rat Offspring.
Liu Y, Yang C, Feng X, Qi L, Guo J, Zhu D, Thai PN, Zhang Y, Zhang P, Sun M, Lv J, Zhang L, Xu Z, Lu X
Molecular nutrition & food research 2020 Jul;64(14):e2000196
Molecular nutrition & food research 2020 Jul;64(14):e2000196
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway.
Ghergurovich JM, García-Cañaveras JC, Wang J, Schmidt E, Zhang Z, TeSlaa T, Patel H, Chen L, Britt EC, Piqueras-Nebot M, Gomez-Cabrera MC, Lahoz A, Fan J, Beier UH, Kim H, Rabinowitz JD
Nature chemical biology 2020 Jul;16(7):731-739
Nature chemical biology 2020 Jul;16(7):731-739
Cortistatin ameliorates Ang II-induced proliferation of vascular smooth muscle cells by inhibiting autophagy through SSTR3 and SSTR5.
Wang Y, Zhang X, Chen W, Gao L, Li J, Song T, Chi J, Zhang X, Shi Z, Dong Y, Yin X, Liu Y
Life sciences 2020 Jul 15;253:117726
Life sciences 2020 Jul 15;253:117726
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.
Lou F, Sun Y, Xu Z, Niu L, Wang Z, Deng S, Liu Z, Zhou H, Bai J, Yin Q, Cai X, Sun L, Wang H, Li Q, Wu Z, Chen X, Gu J, Shi YL, Tao W, Ginhoux F, Wang H
Immunity 2020 Jul 14;53(1):204-216.e10
Immunity 2020 Jul 14;53(1):204-216.e10
Mitochondrial miR-181a-5p promotes glucose metabolism reprogramming in liver cancer by regulating the electron transport chain.
Zhuang X, Chen Y, Wu Z, Xu Q, Chen M, Shao M, Cao X, Zhou Y, Xie M, Shi Y, Zeng Y, Bu H
Carcinogenesis 2020 Jul 14;41(7):972-983
Carcinogenesis 2020 Jul 14;41(7):972-983
Fluoride-induced renal dysfunction via respiratory chain complex abnormal expression and fusion elevation in mice.
Wang HW, Zhu SQ, Liu J, Miao CY, Zhang Y, Zhou BH
Chemosphere 2020 Jan;238:124607
Chemosphere 2020 Jan;238:124607
Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA(2) phosphorylation in experimental ischemic stroke.
Cao C, Zhou J, Wu X, Qian Y, Hong Y, Mu J, Jin L, Zhu C, Li S
Cellular signalling 2020 Feb;66:109467
Cellular signalling 2020 Feb;66:109467
Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.
Wang HW, Liu J, Wei SS, Zhao WP, Zhu SQ, Zhou BH
Chemosphere 2020 Feb;241:125099
Chemosphere 2020 Feb;241:125099
Magnetic Susceptibility Difference-Induced Nucleus Positioning in Gradient Ultrahigh Magnetic Field.
Tao Q, Zhang L, Han X, Chen H, Ji X, Zhang X
Biophysical journal 2020 Feb 4;118(3):578-585
Biophysical journal 2020 Feb 4;118(3):578-585
Bruceine D induces lung cancer cell apoptosis and autophagy via the ROS/MAPK signaling pathway in vitro and in vivo.
Fan J, Ren D, Wang J, Liu X, Zhang H, Wu M, Yang G
Cell death & disease 2020 Feb 18;11(2):126
Cell death & disease 2020 Feb 18;11(2):126
trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop.
Hirata Y, Inoue A, Suzuki S, Takahashi M, Matsui R, Kono N, Noguchi T, Matsuzawa A
Scientific reports 2020 Feb 17;10(1):2743
Scientific reports 2020 Feb 17;10(1):2743
Parkin and Nrf2 prevent oxidative stress-induced apoptosis in intervertebral endplate chondrocytes via inducing mitophagy and anti-oxidant defenses.
Kang L, Liu S, Li J, Tian Y, Xue Y, Liu X
Life sciences 2020 Feb 15;243:117244
Life sciences 2020 Feb 15;243:117244
Flavonoids extracted from mulberry (Morus alba L.) leaf improve skeletal muscle mitochondrial function by activating AMPK in type 2 diabetes.
Meng Q, Qi X, Fu Y, Chen Q, Cheng P, Yu X, Sun X, Wu J, Li W, Zhang Q, Li Y, Wang A, Bian H
Journal of ethnopharmacology 2020 Feb 10;248:112326
Journal of ethnopharmacology 2020 Feb 10;248:112326
Silibinin ameliorats H(2)O(2)-induced cell apoptosis and oxidative stress response by activating Nrf2 signaling in trophoblast cells.
Guo H, Wang Y, Liu D
Acta histochemica 2020 Dec;122(8):151620
Acta histochemica 2020 Dec;122(8):151620
Brain-Specific Serine-47 Modification of Cytochrome c Regulates Cytochrome c Oxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling.
Kalpage HA, Wan J, Morse PT, Lee I, Hüttemann M
Cells 2020 Aug 6;9(8)
Cells 2020 Aug 6;9(8)
16-Hydroxycleroda-3,13-dien-15,16-olide Induces Apoptosis in Human Bladder Cancer Cells through Cell Cycle Arrest, Mitochondria ROS Overproduction, and Inactivation of EGFR-Related Signalling Pathways.
Chen YC, Wang PY, Huang BM, Chen YJ, Lee WC, Chen YC
Molecules (Basel, Switzerland) 2020 Aug 30;25(17)
Molecules (Basel, Switzerland) 2020 Aug 30;25(17)
Transplantation of platelet-derived mitochondria alleviates cognitive impairment and mitochondrial dysfunction in db/db mice.
Ma H, Jiang T, Tang W, Ma Z, Pu K, Xu F, Chang H, Zhao G, Gao W, Li Y, Wang Q
Clinical science (London, England : 1979) 2020 Aug 28;134(16):2161-2175
Clinical science (London, England : 1979) 2020 Aug 28;134(16):2161-2175
Antagomirs targeting miR-142-5p attenuate pilocarpine-induced status epilepticus in mice.
Zhang H, Lian Y, Xie N, Cheng X, Chen C, Xu H, Zheng Y
Experimental cell research 2020 Aug 15;393(2):112089
Experimental cell research 2020 Aug 15;393(2):112089
Deregulated MTOR (mechanistic target of rapamycin kinase) is responsible for autophagy defects exacerbating kidney stone development.
Unno R, Kawabata T, Taguchi K, Sugino T, Hamamoto S, Ando R, Okada A, Kohri K, Yoshimori T, Yasui T
Autophagy 2020 Apr;16(4):709-723
Autophagy 2020 Apr;16(4):709-723
Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells.
Yang X, Chen G, Yu KN, Yang M, Peng S, Ma J, Qin F, Cao W, Cui S, Nie L, Han W
Cell death & disease 2020 Apr 27;11(4):295
Cell death & disease 2020 Apr 27;11(4):295
Lanthanum chloride impairs spatial learning and memory by inducing [Ca(2+)](m) overload, mitochondrial fission-fusion disorder and excessive mitophagy in hippocampal nerve cells of rats.
Yu M, Yang J, Gao X, Sun W, Liu S, Han Y, Lu X, Jin C, Wu S, Cai Y
Metallomics : integrated biometal science 2020 Apr 1;12(4):592-606
Metallomics : integrated biometal science 2020 Apr 1;12(4):592-606
A novel STAT3 inhibitor, HJC0152, exerts potent antitumor activity in glioblastoma.
Li Z, Zhu T, Xu Y, Wu C, Chen J, Ren Y, Kong L, Sun S, Guo W, Wang Y, Jing C, Dong J, Zhou J, Zhang L, Shen Q, Zhou X
American journal of cancer research 2019;9(4):699-713
American journal of cancer research 2019;9(4):699-713
Mitochondrial DNA 3,860-bp Deletion Increases with Aging in the Auditory Nervous System of C57BL/6J Mice.
Du ZD, He L, Tu C, Guo XA, Yu S, Liu K, Gong S
ORL; journal for oto-rhino-laryngology and its related specialties 2019;81(2-3):92-100
ORL; journal for oto-rhino-laryngology and its related specialties 2019;81(2-3):92-100
Modulations of Histone Deacetylase 2 Offer a Protective Effect through the Mitochondrial Apoptosis Pathway in Acute Liver Failure.
Wang Y, Yang F, Jiao FZ, Chen Q, Zhang WB, Wang LW, Gong ZJ
Oxidative medicine and cellular longevity 2019;2019:8173016
Oxidative medicine and cellular longevity 2019;2019:8173016
Determination of the Molecular Mechanism of Torularhodin against Hepatic Oxidative Damage by Transcriptome Analysis.
Li J, Guo Y, Cheng Y, Pi F, Yao W, Xie Y, Qian H
Oxidative medicine and cellular longevity 2019;2019:7417263
Oxidative medicine and cellular longevity 2019;2019:7417263
NADPH Oxidase 2-Mediated Insult in the Auditory Cortex of Zucker Diabetic Fatty Rats.
Du ZD, Wei W, Yu S, Song QL, Liu K, Gong SS
Neural plasticity 2019;2019:3591605
Neural plasticity 2019;2019:3591605
Upregulation of UCP2 Expression Protects against LPS-Induced Oxidative Stress and Apoptosis in Cardiomyocytes.
Huang J, Peng W, Zheng Y, Hao H, Li S, Yao Y, Ding Y, Zhang J, Lyu J, Zeng Q
Oxidative medicine and cellular longevity 2019;2019:2758262
Oxidative medicine and cellular longevity 2019;2019:2758262
Fetal bovine serum inhibits neomycin-induced apoptosis of hair cell-like HEI-OC-1 cells by maintaining mitochondrial function.
Guan M, Zhang Y, Huang Q, He L, Fang Q, Zhang J, Gao S, Fang J, Ma Y, Su K, Gao X
American journal of translational research 2019;11(3):1343-1358
American journal of translational research 2019;11(3):1343-1358
SIRT5 Promotes Hepatocellular Carcinoma Progression by Regulating Mitochondrial Apoptosis.
Zhang R, Wang C, Tian Y, Yao Y, Mao J, Wang H, Li Z, Xu Y, Ye M, Wang L
Journal of Cancer 2019;10(16):3871-3882
Journal of Cancer 2019;10(16):3871-3882
NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly.
Hou T, Zhang R, Jian C, Ding W, Wang Y, Ling S, Ma Q, Hu X, Cheng H, Wang X
Cell research 2019 Sep;29(9):754-766
Cell research 2019 Sep;29(9):754-766
Bone marrow adipose tissue-derived stem cell factor mediates metabolic regulation of hematopoiesis.
Zhang Z, Huang Z, Ong B, Sahu C, Zeng H, Ruan HB
Haematologica 2019 Sep;104(9):1731-1743
Haematologica 2019 Sep;104(9):1731-1743
Mitochondria-Targeting Thermosensitive Initiator with Enhanced Anticancer Efficiency.
Peng M, Wang XQ, Zhang Y, Li CX, Zhang M, Cheng H, Zhang XZ
ACS applied bio materials 2019 Oct 21;2(10):4656-4666
ACS applied bio materials 2019 Oct 21;2(10):4656-4666
GCN5L1 controls renal lipotoxicity through regulating acetylation of fatty acid oxidation enzymes.
Lv T, Hu Y, Ma Y, Zhen J, Xin W, Wan Q
Journal of physiology and biochemistry 2019 Nov;75(4):597-606
Journal of physiology and biochemistry 2019 Nov;75(4):597-606
Deficiency of mitophagy receptor FUNDC1 impairs mitochondrial quality and aggravates dietary-induced obesity and metabolic syndrome.
Wu H, Wang Y, Li W, Chen H, Du L, Liu D, Wang X, Xu T, Liu L, Chen Q
Autophagy 2019 Nov;15(11):1882-1898
Autophagy 2019 Nov;15(11):1882-1898
Viral Nonstructural Protein 1 Induces Mitochondrion-Mediated Apoptosis in Mink Enteritis Virus Infection.
Lin P, Cheng Y, Song S, Qiu J, Yi L, Cao Z, Li J, Cheng S, Wang J
Journal of virology 2019 Nov 15;93(22)
Journal of virology 2019 Nov 15;93(22)
A novel ALK inhibitor ZYY inhibits Karpas299 cell growth in vitro and in a mouse xenograft model and induces protective autophagy.
Shen J, Wang J, Du J, Wang L, Zhou X, Chang X, Li Z, Zhai X, Zuo D, Wu Y
Toxicology and applied pharmacology 2019 Nov 15;383:114781
Toxicology and applied pharmacology 2019 Nov 15;383:114781
Benzoylaconine induces mitochondrial biogenesis in mice via activating AMPK signaling cascade.
Deng XH, Liu JJ, Sun XJ, Dong JC, Huang JH
Acta pharmacologica Sinica 2019 May;40(5):658-665
Acta pharmacologica Sinica 2019 May;40(5):658-665
Mutations in the MRPS28 gene encoding the small mitoribosomal subunit protein bS1m in a patient with intrauterine growth retardation, craniofacial dysmorphism and multisystemic involvement.
Pulman J, Ruzzenente B, Bianchi L, Rio M, Boddaert N, Munnich A, Rötig A, Metodiev MD
Human molecular genetics 2019 May 1;28(9):1445-1462
Human molecular genetics 2019 May 1;28(9):1445-1462
NADPH oxidase inhibitor apocynin decreases mitochondrial dysfunction and apoptosis in the ventral cochlear nucleus of D-galactose-induced aging model in rats.
Du ZD, Yu S, Qi Y, Qu TF, He L, Wei W, Liu K, Gong SS
Neurochemistry international 2019 Mar;124:31-40
Neurochemistry international 2019 Mar;124:31-40
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression.
Ma B, Cheng H, Mu C, Geng G, Zhao T, Luo Q, Ma K, Chang R, Liu Q, Gao R, Nie J, Xie J, Han J, Chen L, Ma G, Zhu Y, Chen Q
Nature communications 2019 Mar 4;10(1):1034
Nature communications 2019 Mar 4;10(1):1034
Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales.
Du Y, Hu H, Pei X, Du K, Wei T
Bioconjugate chemistry 2019 Mar 20;30(3):826-832
Bioconjugate chemistry 2019 Mar 20;30(3):826-832
2-D08 as a SUMOylation inhibitor induced ROS accumulation mediates apoptosis of acute myeloid leukemia cells possibly through the deSUMOylation of NOX2.
Zhou P, Chen X, Li M, Tan J, Zhang Y, Yuan W, Zhou J, Wang G
Biochemical and biophysical research communications 2019 Jun 11;513(4):1063-1069
Biochemical and biophysical research communications 2019 Jun 11;513(4):1063-1069
Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy.
Guo T, Liu T, Sun Y, Liu X, Xiong R, Li H, Li Z, Zhang Z, Tian Z, Tian Y
Cell death & disease 2019 Jun 11;10(6):457
Cell death & disease 2019 Jun 11;10(6):457
Phosphorylation of MAVS/VISA by Nemo-like kinase (NLK) for degradation regulates the antiviral innate immune response.
Li SZ, Shu QP, Song Y, Zhang HH, Liu Y, Jin BX, Liuyu TZ, Li C, Huang XC, Du RL, Song W, Zhong B, Zhang XD
Nature communications 2019 Jul 19;10(1):3233
Nature communications 2019 Jul 19;10(1):3233
Phenylephrine Alleviates (131)I Radiation Damage in Submandibular Gland Through Maintaining Mitochondrial Homeostasis.
Wang XY, Yu J, Zhang FY, Liu KJ, Xiang B
International journal of radiation oncology, biology, physics 2019 Jul 1;104(3):644-655
International journal of radiation oncology, biology, physics 2019 Jul 1;104(3):644-655
Effects of resveratrol on regulation on UCP2 and cardiac function in diabetic rats.
Diao J, Wei J, Yan R, Fan G, Lin L, Chen M
Journal of physiology and biochemistry 2019 Feb;75(1):39-51
Journal of physiology and biochemistry 2019 Feb;75(1):39-51
Brain microvascular endothelial cell exosome-mediated S100A16 up-regulation confers small-cell lung cancer cell survival in brain.
Xu ZH, Miao ZW, Jiang QZ, Gan DX, Wei XG, Xue XZ, Li JQ, Zheng F, Qin XX, Fang WG, Chen YH, Li B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Feb;33(2):1742-1757
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Feb;33(2):1742-1757
NDUFAB1 protects against obesity and insulin resistance by enhancing mitochondrial metabolism.
Zhang R, Hou T, Cheng H, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):13310-13322
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Dec;33(12):13310-13322
Mitochondrial respiratory chain dysfunction mediated by ROS is a primary point of fluoride-induced damage in Hepa1-6 cells.
Wang HW, Zhang Y, Tan PP, Jia LS, Chen Y, Zhou BH
Environmental pollution (Barking, Essex : 1987) 2019 Dec;255(Pt 3):113359
Environmental pollution (Barking, Essex : 1987) 2019 Dec;255(Pt 3):113359
Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum.
Tang Z, Zhang Z, Zhang H, Wang Y, Zhang Y, Zhao J, Yang H, Wang Z
Cells 2019 Dec 27;9(1)
Cells 2019 Dec 27;9(1)
Liraglutide ameliorates non-alcoholic steatohepatitis by inhibiting NLRP3 inflammasome and pyroptosis activation via mitophagy.
Yu X, Hao M, Liu Y, Ma X, Lin W, Xu Q, Zhou H, Shao N, Kuang H
European journal of pharmacology 2019 Dec 1;864:172715
European journal of pharmacology 2019 Dec 1;864:172715
Promotion of Mitochondrial Biogenesis via Activation of AMPK-PGC1ɑ Signaling Pathway by Ginger (Zingiber officinale Roscoe) Extract, and Its Major Active Component 6-Gingerol.
Deng X, Zhang S, Wu J, Sun X, Shen Z, Dong J, Huang J
Journal of food science 2019 Aug;84(8):2101-2111
Journal of food science 2019 Aug;84(8):2101-2111
EIF4G1 is a novel candidate gene associated with severe asthenozoospermia.
Sha Y, Liu W, Huang X, Li Y, Ji Z, Mei L, Lin S, Kong S, Lu J, Kong L, Zhu X, Lu Z, Ding L
Molecular genetics & genomic medicine 2019 Aug;7(8):e807
Molecular genetics & genomic medicine 2019 Aug;7(8):e807
Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes.
Kang Y, Li Y, Zhang T, Chi Y, Liu M
International journal of molecular medicine 2019 Aug;44(2):447-456
International journal of molecular medicine 2019 Aug;44(2):447-456
MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1.
Zhao X, Jin Y, Li L, Xu L, Tang Z, Qi Y, Yin L, Peng J
Pharmacological research 2019 Aug;146:104276
Pharmacological research 2019 Aug;146:104276
Zinc accumulation in mitochondria promotes ischemia-induced BBB disruption through Drp1-dependent mitochondria fission.
Qi Z, Shi W, Zhao Y, Ji X, Liu KJ
Toxicology and applied pharmacology 2019 Aug 15;377:114601
Toxicology and applied pharmacology 2019 Aug 15;377:114601
Increased Dynamin-Related Protein 1-Dependent Mitochondrial Fission Contributes to High-Fat-Diet-Induced Cardiac Dysfunction and Insulin Resistance by Elevating Tafazzin in Mouse Hearts.
Chang W, Xiao D, Ao X, Li M, Xu T, Wang J
Molecular nutrition & food research 2019 Apr;63(7):e1801322
Molecular nutrition & food research 2019 Apr;63(7):e1801322
O-GlcNAcylation on Rab3A attenuates its effects on mitochondrial oxidative phosphorylation and metastasis in hepatocellular carcinoma.
Wu W, Zheng X, Wang J, Yang T, Dai W, Song S, Fang L, Wang Y, Gu J
Cell death & disease 2018 Sep 20;9(10):970
Cell death & disease 2018 Sep 20;9(10):970
SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice.
Du Y, Hu H, Qu S, Wang J, Hua C, Zhang J, Wei P, He X, Hao J, Liu P, Yang F, Li T, Wei T
EBioMedicine 2018 Oct;36:347-357
EBioMedicine 2018 Oct;36:347-357
A high-fat diet impairs mitochondrial biogenesis, mitochondrial dynamics, and the respiratory chain complex in rat myocardial tissues.
Chen D, Li X, Zhang L, Zhu M, Gao L
Journal of cellular biochemistry 2018 Nov;119(11):9602
Journal of cellular biochemistry 2018 Nov;119(11):9602
Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance.
Kou G, Li Z, Wu C, Liu Y, Hu Y, Guo L, Xu X, Zhou Z
Journal of agricultural and food chemistry 2018 Nov 14;66(45):11917-11925
Journal of agricultural and food chemistry 2018 Nov 14;66(45):11917-11925
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
Aulas A, Lyons SM, Fay MM, Anderson P, Ivanov P
Cell death & disease 2018 Nov 13;9(11):1129
Cell death & disease 2018 Nov 13;9(11):1129
PDGFRβ translocates to the nucleus and regulates chromatin remodeling via TATA element-modifying factor 1.
Papadopoulos N, Lennartsson J, Heldin CH
The Journal of cell biology 2018 May 7;217(5):1701-1717
The Journal of cell biology 2018 May 7;217(5):1701-1717
Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity.
Fu T, Xu Z, Liu L, Guo Q, Wu H, Liang X, Zhou D, Xiao L, Liu L, Liu Y, Zhu MS, Chen Q, Gan Z
Cell reports 2018 May 1;23(5):1357-1372
Cell reports 2018 May 1;23(5):1357-1372
Modulation of sphingosine 1-phosphate (S1P) attenuates spatial learning and memory impairments in the valproic acid rat model of autism.
Wu H, Zhang Q, Gao J, Sun C, Wang J, Xia W, Cao Y, Hao Y, Wu L
Psychopharmacology 2018 Mar;235(3):873-886
Psychopharmacology 2018 Mar;235(3):873-886
Hyper-acetylation contributes to the sensitivity of chemo-resistant prostate cancer cells to histone deacetylase inhibitor Trichostatin A.
Xu Q, Liu X, Zhu S, Hu X, Niu H, Zhang X, Zhu D, Nesa EU, Tian K, Yuan H
Journal of cellular and molecular medicine 2018 Mar;22(3):1909-1922
Journal of cellular and molecular medicine 2018 Mar;22(3):1909-1922
Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology.
Jian F, Chen D, Chen L, Yan C, Lu B, Zhu Y, Chen S, Shi A, Chan DC, Song Z
Cell reports 2018 Jun 5;23(10):2989-3005
Cell reports 2018 Jun 5;23(10):2989-3005
NF-κB and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis.
Zeng GZ, Wang Z, Zhao LM, Fan JT, Tan NH
Journal of ethnopharmacology 2018 Jun 28;220:220-227
Journal of ethnopharmacology 2018 Jun 28;220:220-227
Flavagline analog FL3 induces cell cycle arrest in urothelial carcinoma cell of the bladder by inhibiting the Akt/PHB interaction to activate the GADD45α pathway.
Yuan G, Chen X, Liu Z, Wei W, Shu Q, Abou-Hamdan H, Jiang L, Li X, Chen R, Désaubry L, Zhou F, Xie D
Journal of experimental & clinical cancer research : CR 2018 Feb 7;37(1):21
Journal of experimental & clinical cancer research : CR 2018 Feb 7;37(1):21
Involvement of impaired autophagy and mitophagy in Neuro-2a cell damage under hypoxic and/or high-glucose conditions.
Song Y, Du Y, Zou W, Luo Y, Zhang X, Fu J
Scientific reports 2018 Feb 19;8(1):3301
Scientific reports 2018 Feb 19;8(1):3301
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells.
Sun DZ, Song CQ, Xu YM, Wang R, Liu W, Liu Z, Dong XS
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159
Toxicology in vitro : an international journal published in association with BIBRA 2018 Dec;53:148-159
Inhibition of mitochondrial translation in fibroblasts from a patient expressing the KARS p.(Pro228Leu) variant and presenting with sensorineural deafness, developmental delay, and lactic acidosis.
Ruzzenente B, Assouline Z, Barcia G, Rio M, Boddaert N, Munnich A, Rötig A, Metodiev MD
Human mutation 2018 Dec;39(12):2047-2059
Human mutation 2018 Dec;39(12):2047-2059
Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis.
Liu L, Sun Y, Zhao Y, Wang Q, Guo H, Guo R, Liu Y, Fu S, Zhang L, Li Y, Meng Y
Cancer science 2018 Dec;109(12):3762-3773
Cancer science 2018 Dec;109(12):3762-3773
Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway.
Kurmi K, Hitosugi S, Yu J, Boakye-Agyeman F, Wiese EK, Larson TR, Dai Q, Machida YJ, Lou Z, Wang L, Boughey JC, Kaufmann SH, Goetz MP, Karnitz LM, Hitosugi T
Cell metabolism 2018 Dec 4;28(6):833-847.e8
Cell metabolism 2018 Dec 4;28(6):833-847.e8
Overcoming resistance to mitochondrial apoptosis by BZML-induced mitotic catastrophe is enhanced by inhibition of autophagy in A549/Taxol cells.
Bai Z, Gao M, Xu X, Zhang H, Xu J, Guan Q, Wang Q, Du J, Li Z, Zuo D, Zhang W, Wu Y
Cell proliferation 2018 Aug;51(4):e12450
Cell proliferation 2018 Aug;51(4):e12450
Curcumin inhibits the growth of liver cancer stem cells through the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway.
Wang J, Wang C, Bu G
Experimental and therapeutic medicine 2018 Apr;15(4):3650-3658
Experimental and therapeutic medicine 2018 Apr;15(4):3650-3658
The dual role of poly(ADP-ribose) polymerase-1 in modulating parthanatos and autophagy under oxidative stress in rat cochlear marginal cells of the stria vascularis.
Jiang HY, Yang Y, Zhang YY, Xie Z, Zhao XY, Sun Y, Kong WJ
Redox biology 2018 Apr;14:361-370
Redox biology 2018 Apr;14:361-370
The cellular stress proteins CHCHD10 and MNRR1 (CHCHD2): Partners in mitochondrial and nuclear function and dysfunction.
Purandare N, Somayajulu M, Hüttemann M, Grossman LI, Aras S
The Journal of biological chemistry 2018 Apr 27;293(17):6517-6529
The Journal of biological chemistry 2018 Apr 27;293(17):6517-6529
Propofol Through Upregulating Caveolin-3 Attenuates Post-Hypoxic Mitochondrial Damage and Cell Death in H9C2 Cardiomyocytes During Hyperglycemia.
Deng F, Wang S, Zhang L, Xie X, Cai S, Li H, Xie GL, Miao HL, Yang C, Liu X, Xia Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(1):279-292
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(1):279-292
Fish oil feeding reverses hepatomegaly and disrupted hepatic function due to the lack of FXR signaling.
Miyata M, Shinno K, Kinoshita T, Kinoshita Y, Sugiura Y
The Journal of toxicological sciences 2017;42(6):671-681
The Journal of toxicological sciences 2017;42(6):671-681
Inhibition of Caveolae Contributes to Propofol Preconditioning-Suppressed Microvesicles Release and Cell Injury by Hypoxia-Reoxygenation.
Deng F, Wang S, Cai S, Hu Z, Xu R, Wang J, Feng D, Zhang L
Oxidative medicine and cellular longevity 2017;2017:3542149
Oxidative medicine and cellular longevity 2017;2017:3542149
A unique polysaccharide purified from Hericium erinaceus mycelium prevents oxidative stress induced by H2O2 in human gastric mucosa epithelium cell.
Wang M, Kanako N, Zhang Y, Xiao X, Gao Q, Tetsuya K
PloS one 2017;12(7):e0181546
PloS one 2017;12(7):e0181546
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome.
Sbardella D, Tundo GR, Campagnolo L, Valacchi G, Orlandi A, Curatolo P, Borsellino G, D'Esposito M, Ciaccio C, Cesare SD, Pierro DD, Galasso C, Santarone ME, Hayek J, Coletta M, Marini S
Scientific reports 2017 Sep 26;7(1):12297
Scientific reports 2017 Sep 26;7(1):12297
Docosahexaenoic acid increases the expression of oxidative stress-induced growth inhibitor 1 through the PI3K/Akt/Nrf2 signaling pathway in breast cancer cells.
Tsai CH, Shen YC, Chen HW, Liu KL, Chang JW, Chen PY, Lin CY, Yao HT, Li CC
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Oct;108(Pt A):276-288
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Oct;108(Pt A):276-288
Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts.
Hu D, Cao S, Zhang G, Xiao Y, Liu S, Shang Y
Scientific reports 2017 Oct 19;7(1):13554
Scientific reports 2017 Oct 19;7(1):13554
Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.
Liu Z, Wang Y, Wang Y, Dong W, Xia X, Song E, Song Y
Chemical research in toxicology 2017 Oct 16;30(10):1804-1814
Chemical research in toxicology 2017 Oct 16;30(10):1804-1814
Impaired mitochondrial fusion, autophagy, biogenesis and dysregulated lipid metabolism is associated with preeclampsia.
Zhou X, Han TL, Chen H, Baker PN, Qi H, Zhang H
Experimental cell research 2017 Oct 1;359(1):195-204
Experimental cell research 2017 Oct 1;359(1):195-204
PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Xu X, Cui Y, Cao L, Zhang Y, Yin Y, Hu X
Experimental and therapeutic medicine 2017 May;13(5):1993-1999
Experimental and therapeutic medicine 2017 May;13(5):1993-1999
MICU1 Alleviates Diabetic Cardiomyopathy Through Mitochondrial Ca(2+)-Dependent Antioxidant Response.
Ji L, Liu F, Jing Z, Huang Q, Zhao Y, Cao H, Li J, Yin C, Xing J, Li F
Diabetes 2017 Jun;66(6):1586-1600
Diabetes 2017 Jun;66(6):1586-1600
The changes in glucose metabolism and cell proliferation in the kidneys of polycystic kidney disease mini-pig models.
Lian X, Zhao J, Wu X, Zhang Y, Li Q, Lin S, Bai XY, Chen X
Biochemical and biophysical research communications 2017 Jun 24;488(2):374-381
Biochemical and biophysical research communications 2017 Jun 24;488(2):374-381
CSFV induced mitochondrial fission and mitophagy to inhibit apoptosis.
Gou H, Zhao M, Xu H, Yuan J, He W, Zhu M, Ding H, Yi L, Chen J
Oncotarget 2017 Jun 13;8(24):39382-39400
Oncotarget 2017 Jun 13;8(24):39382-39400
Polyphyllin I induces G2/M phase arrest and apoptosis in U251 human glioma cells via mitochondrial dysfunction and the JNK signaling pathway.
Liu J, Zhang Y, Chen L, Yu F, Li X, Dan Tao, Zhao J, Zhou S
Acta biochimica et biophysica Sinica 2017 Jun 1;49(6):479-486
Acta biochimica et biophysica Sinica 2017 Jun 1;49(6):479-486
Mitochondria-Associated Apoptosis in Human Melanoma Cells Induced by Cardanol Monoene from Cashew Nut Shell Liquid.
Su WC, Lin YF, Yu XP, Wang YX, Lin XD, Su QZ, Shen DY, Chen QX
Journal of agricultural and food chemistry 2017 Jul 19;65(28):5620-5631
Journal of agricultural and food chemistry 2017 Jul 19;65(28):5620-5631
Low-level laser therapy for beta amyloid toxicity in rat hippocampus.
Lu Y, Wang R, Dong Y, Tucker D, Zhao N, Ahmed ME, Zhu L, Liu TC, Cohen RM, Zhang Q
Neurobiology of aging 2017 Jan;49:165-182
Neurobiology of aging 2017 Jan;49:165-182
ABT737 induces mitochondrial pathway apoptosis and mitophagy by regulating DRP1-dependent mitochondrial fission in human ovarian cancer cells.
Yu Y, Xu L, Qi L, Wang C, Xu N, Liu S, Li S, Tian H, Liu W, Xu Y, Li Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:22-29
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:22-29
Deficiency of PHB complex impairs respiratory supercomplex formation and activates mitochondrial flashes.
Jian C, Xu F, Hou T, Sun T, Li J, Cheng H, Wang X
Journal of cell science 2017 Aug 1;130(15):2620-2630
Journal of cell science 2017 Aug 1;130(15):2620-2630
CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.
Han Y, Sun S, Zhao M, Zhang Z, Gong S, Gao P, Liu J, Zhou J, Ma D, Gao Q, Wu P
Disease markers 2016;2016:3528064
Disease markers 2016;2016:3528064
Vitamin K2 Induces Mitochondria-Related Apoptosis in Human Bladder Cancer Cells via ROS and JNK/p38 MAPK Signal Pathways.
Duan F, Yu Y, Guan R, Xu Z, Liang H, Hong L
PloS one 2016;11(8):e0161886
PloS one 2016;11(8):e0161886
Mir143-BBC3 cascade reduces microglial survival via interplay between apoptosis and autophagy: Implications for methamphetamine-mediated neurotoxicity.
Zhang Y, Shen K, Bai Y, Lv X, Huang R, Zhang W, Chao J, Nguyen LK, Hua J, Gan G, Hu G, Yao H
Autophagy 2016 Sep;12(9):1538-59
Autophagy 2016 Sep;12(9):1538-59
Oral quercetin administration transiently protects respiratory function in dystrophin-deficient mice.
Selsby JT, Ballmann CG, Spaulding HR, Ross JW, Quindry JC
The Journal of physiology 2016 Oct 15;594(20):6037-6053
The Journal of physiology 2016 Oct 15;594(20):6037-6053
ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy.
Li TY, Sun Y, Liang Y, Liu Q, Shi Y, Zhang CS, Zhang C, Song L, Zhang P, Zhang X, Li X, Chen T, Huang HY, He X, Wang Y, Wu YQ, Chen S, Jiang M, Chen C, Xie C, Yang JY, Lin Y, Zhao S, Ye Z, Lin SY, Chiu DT, Lin SC
Molecular cell 2016 May 5;62(3):359-370
Molecular cell 2016 May 5;62(3):359-370
Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway.
Li X, Song Y, Zhang P, Zhu H, Chen L, Xiao Y, Xing Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jun;37(6):7599-613
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jun;37(6):7599-613
Effects of a block in cysteine catabolism on energy balance and fat metabolism in mice.
Niewiadomski J, Zhou JQ, Roman HB, Liu X, Hirschberger LL, Locasale JW, Stipanuk MH
Annals of the New York Academy of Sciences 2016 Jan;1363(1):99-115
Annals of the New York Academy of Sciences 2016 Jan;1363(1):99-115
Identification of a novel mitochondrial interacting protein of C1QBP using subcellular fractionation coupled with CoIP-MS.
Chen R, Xiao M, Gao H, Chen Y, Li Y, Liu Y, Zhang N
Analytical and bioanalytical chemistry 2016 Feb;408(6):1557-64
Analytical and bioanalytical chemistry 2016 Feb;408(6):1557-64
HDAC4 mediates IFN-γ induced disruption of energy expenditure-related gene expression by repressing SIRT1 transcription in skeletal muscle cells.
Fang M, Fan Z, Tian W, Zhao Y, Li P, Xu H, Zhou B, Zhang L, Wu X, Xu Y
Biochimica et biophysica acta 2016 Feb;1859(2):294-305
Biochimica et biophysica acta 2016 Feb;1859(2):294-305
Liraglutide suppresses obesity and induces brown fat-like phenotype via Soluble Guanylyl Cyclase mediated pathway in vivo and in vitro.
Zhu E, Yang Y, Zhang J, Li Y, Li C, Chen L, Sun B
Oncotarget 2016 Dec 6;7(49):81077-81089
Oncotarget 2016 Dec 6;7(49):81077-81089
Pseudolaric acid B induces mitotic arrest and apoptosis in both 5-fluorouracil-sensitive and -resistant colorectal cancer cells.
Wen C, Chen J, Zhang D, Wang H, Che J, Qin Q, He L, Cai Z, Lin M, Lou Q, Huang L, Chen D, Iwamoto A, Ren D, Wang L, Lan P, Wang J, Liu H, Yang X
Cancer letters 2016 Dec 28;383(2):295-308
Cancer letters 2016 Dec 28;383(2):295-308
Exercise Inducible Lactate Dehydrogenase B Regulates Mitochondrial Function in Skeletal Muscle.
Liang X, Liu L, Fu T, Zhou Q, Zhou D, Xiao L, Liu J, Kong Y, Xie H, Yi F, Lai L, Vega RB, Kelly DP, Smith SR, Gan Z
The Journal of biological chemistry 2016 Dec 2;291(49):25306-25318
The Journal of biological chemistry 2016 Dec 2;291(49):25306-25318
Acetyl-coenzyme A carboxylase alpha promotion of glucose-mediated fatty acid synthesis enhances survival of hepatocellular carcinoma in mice and patients.
Wang MD, Wu H, Fu GB, Zhang HL, Zhou X, Tang L, Dong LW, Qin CJ, Huang S, Zhao LH, Zeng M, Wu MC, Yan HX, Wang HY
Hepatology (Baltimore, Md.) 2016 Apr;63(4):1272-86
Hepatology (Baltimore, Md.) 2016 Apr;63(4):1272-86
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Yao Z, Sun B, Hong Q, Yan J, Mu D, Li J, Sheng H, Guo H
Drug design, development and therapy 2015;9:5911-23
Drug design, development and therapy 2015;9:5911-23
PCSK9 regulates apoptosis in human neuroglioma u251 cells via mitochondrial signaling pathways.
Piao MX, Bai JW, Zhang PF, Zhang YZ
International journal of clinical and experimental pathology 2015;8(3):2787-94
International journal of clinical and experimental pathology 2015;8(3):2787-94
8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition.
Yang H, Xiong J, Luo W, Yang J, Xi T
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;37(1):361-74
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;37(1):361-74
FUS Interacts with HSP60 to Promote Mitochondrial Damage.
Deng J, Yang M, Chen Y, Chen X, Liu J, Sun S, Cheng H, Li Y, Bigio EH, Mesulam M, Xu Q, Du S, Fushimi K, Zhu L, Wu JY
PLoS genetics 2015 Sep;11(9):e1005357
PLoS genetics 2015 Sep;11(9):e1005357
Development of a mitochondria-based centrifugal ultrafiltration/liquid chromatography/mass spectrometry method for screening mitochondria-targeted bioactive constituents from complex matrixes: Herbal medicines as a case study.
Yang XX, Xu F, Wang D, Yang ZW, Tan HR, Shang MY, Wang X, Cai SQ
Journal of chromatography. A 2015 Sep 25;1413:33-46
Journal of chromatography. A 2015 Sep 25;1413:33-46
Reduction of zinc accumulation in mitochondria contributes to decreased cerebral ischemic injury by normobaric hyperoxia treatment in an experimental stroke model.
Dong W, Qi Z, Liang J, Shi W, Zhao Y, Luo Y, Ji X, Liu KJ
Experimental neurology 2015 Oct;272:181-9
Experimental neurology 2015 Oct;272:181-9
Bcl-2 phosphorylation triggers autophagy switch and reduces mitochondrial damage in limb remote ischemic conditioned rats after ischemic stroke.
Qi Z, Dong W, Shi W, Wang R, Zhang C, Zhao Y, Ji X, Liu KJ, Luo Y
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N -methyl- N -nitrosourea-induced retinal degeneration in mice.
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Mitochondrial bioenergetic deficits in the hippocampi of rats with chronic ischemia-induced vascular dementia.
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 11242-1-AP(COXIV antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using COX4I1 antibody 11242-1-AP at 1:50 dilution and FITC-labeled donkey anti-rabbit IgG(green).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-COXIV (IP:11242-1-AP, 3ug; Detection:11242-1-AP 1:1000) with mouse skeletal muscle tissue lysate 3500ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 11242-1-AP(COXIV antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
