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- Antibody Data
- Antigen structure
- References [137]
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- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 14742-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14742-1-AP, RRID:AB_2241442
- Product name
- UQCRC2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated UQCRC2 antibody (Cat. #14742-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Characterization of a UQCRC1 variant in a patient with progressive weakness, pain and sleep issues reveals a functional mitochondrial defect restored by mitochondrial transplantation.
Resveratrol alleviates neuropathic pain associated with restoration of mitochondrial fission-fusion balance in CCI mice.
Chronic cold exposure induces plasticity of mitochondrial calcium uptake in beige and brown fat of UCP1-deficient mice.
Hyperacetylation escalates myocardial susceptibility to ischemia reperfusion injury by mediating mitochondrial supercomplexes assembly in T2DM.
Echinacoside modulates PARP14-GLUD1 axis to mediate energy metabolism reprogramming and mitochondrial function in diminished ovarian reserve.
Evolutionarily conserved signaling intermediate in Toll pathways facilitates exercise-induced amelioration of skeletal muscle atrophy by maintaining mitochondrial quality control in middle-aged mice.
Mitochondrial remodeling in skeletal muscle underlies exercise-induced reversal of age-associated functional decline in mice and humans.
Loss of STARD7 Impairs Mitochondrial Phospholipid Homeostasis and Contributes to Mitochondrial Myopathy.
Exercise induces sex-specific assembly of mitochondrial supercomplexes.
Spatiotemporal controlled release of YCM/Cu(2)⁺ hydrogel microneedle system synergistically accelerates chronic wound healing in diabetes.
Comparative Proteomic Profiling of Microdissected Spindle and Epithelioid Uveal Melanoma Subtypes.
Hexokinase-2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis Through Metabolic Reprogramming.
Gut microbiota modified by Mulberry leaf water extract improves T2DM through browning of WAT/BAT activation mediated by SCFAs-AMPK/SIRT1/PGC-1α signaling pathway.
C19orf12 inhibits mitochondrial function and enhances the antitumor effects of metformin in non-small cell lung cancer.
Mdivi-1 promotes steroidogenesis in granulosa cells by inhibiting mitochondrial fission.
A galacturonan from sea buckthorn (Hippophae rhamnoides L.) berry modulates dyslipidemia by promoting hepatic lipolysis and mitochondrial oxidation.
Preconception paternal exposure to zearalenone impairs male fertility and IVF embryo survival in mice.
Iron accumulation in hypothalamus promotes age-dependent obesity and metabolic dysfunction of male mice.
TRAP1 inhibits KANSL3 acetylation to alleviate mitochondrial dysfunction by promoting mitophagy in cardiomyocytes under diabetic conditions.
FXR suppress Müller cell activation by regulating cGAS/STING pathway in diabetic retinopathy.
Targeting LARP1 to mitigate aging in lens epithelial cells: mechanistic insights into mitochondrial dysfunction.
Regulatory role of sirtuin-1 by targeting MDM2 to mitochondria-associated membranes formation in the treatment of NAFLD.
CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology.
P-Type Pentatricopeptide Repeat Proteins YS1 and YS2 Function in Splicing of petB Intron to Maintain Chloroplast Homeostasis During Rice Seedling Development.
Selenoprotein K Confers Protection against Iron Dyshomeostasis-Related Neurotoxicity by Regulating the Palmitoylation of TfR-1.
Targeting mitochondrial complex I of CD177(+) neutrophils alleviates lung ischemia-reperfusion injury.
Effects of polystyrene microparticles exposures on spermatogenic cell differentiation and reproductive endpoints in male mice.
Isolated Mitochondrial Transplantation as a Novel Treatment for Corneal Chemical Burns.
Neurotoxicity of Realgar: Crosstalk Between UBXD8-DRP1-Regulated Mitochondrial Fission and PINK1-Parkin-Mediated Mitophagy.
Peptide YY fragment PYY1-36 disrupts mitochondrial biogenesis via RBM43-dependent PGC-1α translation inhibition.
The crucial function of IDO1 in pulmonary fibrosis: From the perspective of mitochondrial fusion in lung fibroblasts and targeted molecular inhibition.
Corticosterone induces fatty liver syndrome in chickens via glucocorticoid receptor and inhibition of mitochondrial supercomplex formation.
hUC-MSC preserves erectile function by restoring mitochondrial mass of penile smooth muscle cells in a rat model of cavernous nerve injury via SIRT1/PGC-1a/TFAM signaling.
CISD2-mediated mitochondrial dysfunction and iron redistribution contributes to ferroptosis in arsenic-induced nonalcoholic steatohepatitis.
Triptolide exposure triggers ovarian inflammation by activating cGAS-STING pathway and decrease oocyte quality in mouse.
Aptamer-Conjugated Exosomes Ameliorate Diabetes-Induced Muscle Atrophy by Enhancing SIRT1/FoxO1/3a-Mediated Mitochondrial Function.
CRIP1 inhibits cutaneous melanoma progression through TFAM-mediated mitochondrial biogenesis.
Qihuang Zhuyu formula modulates mitochondrial function to inhibit platelet activation via endocannabinoid signaling mediated by the SIRT1/PPARα pathway.
MDPAO1 peptide from human milk enhances brown adipose tissue thermogenesis and mitigates obesity.
CD147 mitochondria translocation induced airway remodeling in asthmatic mouse models by regulating M2 macrophage polarization via ANT1-mediated mitophagy.
NAD(+) Enhanced Mesenchymal Stromal Cells Effect on Muscle Atrophy by Improving SIRT1-Mediated Mitochondrial Function via NAMPT.
Sexual dimorphism on the acute effect of exercise in the morning vs. evening: A randomized crossover study.
Kaempferol exerts anti-colorectal cancer effects through its multi-target mediated glucose metabolism remodeling.
Defective vascular smooth muscle cell tafazzin impairs mitochondrial function and promotes atherosclerosis in preclinical models.
Darunavir analog precursors target mitochondrial metabolism in multiple myeloma and CLL.
Liraglutide alleviates diabetic cardiomyopathy in streptozotocin-induced diabetic rats by enhancing mitophagy mediated by the AMPK-Parkin signaling pathway.
CX3CL1 deficiency ameliorates acute kidney injury by inhibiting macrophage mitochondrial dysfunction and mtDNA-cGAS-STING signaling.
Markers of mitochondrial function and oxidative metabolism in skeletal muscle do not display intrinsic circadian regulation in female mice.
Downhill running induced mitophagy in rat soleus muscle via the AMPK pathway.
HIF-1α mediates mitochondrial damage by down-regulating ALKBH7 expression to promote the aberrant activation of FLS in rheumatoid arthritis.
Supercomplex Restructuring in Heart Mitochondria of COX7A1-Deficient Mice.
A robust method for assessing mitochondrial function in healthy and diseased frozen cardiac tissue.
Clioquinol induces mitochondrial toxicity in SH-SY5Y neuroblastoma cells by affecting the respiratory chain complex IV and OPA1 dynamin-like GTPase.
Idebenone improves mitochondrial respiratory activity and attenuates oxidative damage via the SIRT3-SOD2 pathway in a prion disease cell model.
Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue.
Nucleophosmin 1 promotes mucosal immunity by supporting mitochondrial oxidative phosphorylation and ILC3 activity.
Early heart and skeletal muscle mitochondrial response to a moderate hypobaric hypoxia environment.
Acrylamide Exposure Impairs Ovarian Tricarboxylic Acid Cycle and Reduces Oocyte Quality in Mouse.
Integrated analyses of multi-omic data derived from paired primary lung cancer and brain metastasis reveal the metabolic vulnerability as a novel therapeutic target.
A transmitochondrial sodium gradient controls membrane potential in mammalian mitochondria.
Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway.
Defective mitochondria remodelling in B cells leads to an aged immune response.
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
Nmnat1 Deficiency Causes Mitoribosome Excess in Diabetic Nephropathy Mediated by Transcriptional Repressor HIC1.
Redistribution of defective mitochondria-mediated dihydroorotate dehydrogenase imparts 5-fluorouracil resistance in colorectal cancer.
SCAF1 drives the compositional diversity of mammalian respirasomes.
Cox7a1 controls skeletal muscle physiology and heart regeneration through complex IV dimerization.
Radiation-induced changes in energy metabolism result in mitochondrial dysfunction in salivary glands.
Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease.
Mitochondria isolated from lipid droplets of white adipose tissue reveal functional differences based on lipid droplet size.
AMPK phosphorylation of FNIP1 (S220) controls mitochondrial function and muscle fuel utilization during exercise.
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.
CHCHD10(P80L) knock-in zebrafish display a mild ALS-like phenotype.
KARS Mutations Impair Brain Myelination by Inducing Oligodendrocyte Deficiency: One Potential Mechanism and Improvement by Melatonin.
Lysosomes drive the piecemeal removal of mitochondrial inner membrane.
Mitochondrial translation is the primary determinant of secondary mitochondrial complex I deficiencies.
Mesenchymal stromal cells ameliorate mitochondrial dysfunction in α cells and hyperglucagonemia in type 2 diabetes via SIRT1/FoxO3a signaling.
Mitochondria-mediated ferroptosis induced by CARD9 ablation prevents MDSCs-dependent antifungal immunity.
Aerobic exercise enhances mitochondrial homeostasis to counteract D-galactose-induced sarcopenia in zebrafish.
Oat β-D-glucan ameliorates type II diabetes through TLR4/PI3K/AKT mediated metabolic axis.
TGR5 supresses cGAS/STING pathway by inhibiting GRP75-mediated endoplasmic reticulum-mitochondrial coupling in diabetic retinopathy.
A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation.
Radiation-Induced Changes in Energy Metabolism Result in Mitochondrial Dysfunction in Salivary Glands.
Iron derived from NCOA4-mediated ferritinophagy causes cellular senescence via the cGAS-STING pathway.
FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.
Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies.
Impairment of adrenergically-regulated thermogenesis in brown fat of obesity-resistant mice is compensated by non-shivering thermogenesis in skeletal muscle.
The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.
5-HEPE reduces obesity and insulin resistance by promoting adipose tissue browning through GPR119/AMPK/PGC1α activation.
A high-fat diet increases hepatic mitochondrial turnover through restricted acetylation in a NAFLD mouse model.
Loss of mitochondrial Chchd10 or Chchd2 in zebrafish leads to an ALS-like phenotype and Complex I deficiency independent of the mitochondrial integrated stress response.
Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle.
Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1.
Aristolochic acid I exposure triggers ovarian dysfunction by activating NLRP3 inflammasome and affecting mitochondrial homeostasis.
Diosgenin Inhibits ROS Generation by Modulating NOX4 and Mitochondrial Respiratory Chain and Suppresses Apoptosis in Diabetic Nephropathy.
Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats.
Oncometabolite d-2HG alters T cell metabolism to impair CD8(+) T cell function.
Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene.
FNIP1 regulates adipocyte browning and systemic glucose homeostasis in mice by shaping intracellular calcium dynamics.
Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.
Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I.
LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
MDH2 produced OAA is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle.
Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4.
Slc25a5 regulates adipogenesis by modulating ERK signaling in OP9 cells.
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
The Absence of Parkin Does Not Promote Dopamine or Mitochondrial Dysfunction in PolgA(D257A/D257A) Mitochondrial Mutator Mice.
Biochanin A Inhibits Glioblastoma Growth via Restricting Glycolysis and Mitochondrial Oxidative Phosphorylation.
Punicalagin Protects Against Diabetic Cardiomyopathy by Promoting Opa1-Mediated Mitochondrial Fusion via Regulating PTP1B-Stat3 Pathway.
Imatinib Regulates miR-483-3p and Mitochondrial Respiratory Complexes in Gastrointestinal Stromal Tumors.
Structure and assembly of the mammalian mitochondrial supercomplex CIII(2)CIV.
Single-cell analysis reveals androgen receptor regulates the ER-to-Golgi trafficking pathway with CREB3L2 to drive prostate cancer progression.
Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2.
Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
AMPK-dependent and -independent coordination of mitochondrial function and muscle fiber type by FNIP1.
Predominant cellular mitochondrial dysfunction in the TOP3A gene-caused Bloom syndrome-like disorder.
OMA1 reprograms metabolism under hypoxia to promote colorectal cancer development.
Deficiency of β-carotene oxygenase 2 induces mitochondrial fragmentation and activates the STING-IRF3 pathway in the mouse hypothalamus.
Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca(2+) Homeostasis, and Bcl2 Expression.
Analyzing electron transport chain supercomplexes.
Functional role of respiratory supercomplexes in mice: SCAF1 relevance and segmentation of the Q(pool).
Scaf1 promotes respiratory supercomplexes and metabolic efficiency in zebrafish.
NCLX prevents cell death during adrenergic activation of the brown adipose tissue.
A novel approach to measure mitochondrial respiration in frozen biological samples.
Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function.
Romo1 is involved in the immune response of glioblastoma by regulating the function of macrophages.
Mitochondria in Embryogenesis: An Organellogenesis Perspective.
Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy.
A Novel Tumor-Suppressor, CDH18, Inhibits Glioma Cell Invasiveness Via UQCRC2 and Correlates with the Prognosis of Glioma Patients.
Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity.
Glutathione Reduction of Patulin-Evoked Cytotoxicity in HEK293 Cells by the Prevention of Oxidative Damage and the Mitochondrial Apoptotic Pathway.
CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.
Mitochondrial Sirtuin Network Reveals Dynamic SIRT3-Dependent Deacetylation in Response to Membrane Depolarization.
Mechanism of super-assembly of respiratory complexes III and IV.
COA7 (C1orf163/RESA1) mutations associated with mitochondrial leukoencephalopathy and cytochrome c oxidase deficiency.
Piroli GG, Myers R, Holloway L, Hayek A, Linebaugh E, Jones JR, Skinner C, Skinner SA, Frizzell N, Steet R
Molecular genetics and metabolism reports 2026 Mar;46:101302
Molecular genetics and metabolism reports 2026 Mar;46:101302
Resveratrol alleviates neuropathic pain associated with restoration of mitochondrial fission-fusion balance in CCI mice.
Xie L, Xu Y, Yang Q, Chang W, Song L, Sun Y
Scientific reports 2026 Mar 4;16(1)
Scientific reports 2026 Mar 4;16(1)
Chronic cold exposure induces plasticity of mitochondrial calcium uptake in beige and brown fat of UCP1-deficient mice.
Chamorro CG, Pathuri S, Acin-Perez R, Chhan M, Milner MG, Ermolova N, Jones AE, Divakaruni AS, Stiles L, Hevener AL, Zhou Z, Shirihai OS, Kirichok Y, Bertholet AM
bioRxiv : the preprint server for biology 2026 Mar 18;
bioRxiv : the preprint server for biology 2026 Mar 18;
Hyperacetylation escalates myocardial susceptibility to ischemia reperfusion injury by mediating mitochondrial supercomplexes assembly in T2DM.
Deng Y, Yang W, Yang J, Ji L, Xie M, Tang K, He Q, Hu G, Shangguan W, Jiang C, Li T
Redox biology 2026 Jun;93:104163
Redox biology 2026 Jun;93:104163
Echinacoside modulates PARP14-GLUD1 axis to mediate energy metabolism reprogramming and mitochondrial function in diminished ovarian reserve.
Liang H, Shu C, Huang Z, Yuan S, Yang Q, Chen S, Zhou X, Yang N, Xiang X, Xia Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158100
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158100
Evolutionarily conserved signaling intermediate in Toll pathways facilitates exercise-induced amelioration of skeletal muscle atrophy by maintaining mitochondrial quality control in middle-aged mice.
Fan J, Wen X, Duan X, Zhang X, Zhang T
The journals of gerontology. Series A, Biological sciences and medical sciences 2026 Apr 7;81(5)
The journals of gerontology. Series A, Biological sciences and medical sciences 2026 Apr 7;81(5)
Mitochondrial remodeling in skeletal muscle underlies exercise-induced reversal of age-associated functional decline in mice and humans.
García-Domínguez E, García-Domínguez C, Cabrera-Alarcón JL, Muñoz-Hernández MDM, Hernansanz-Agustín P, Curtabbi A, Domenech-Fernandez J, Calvo E, Vázquez J, Serrano AL, Muñoz-Cánoves P, Olaso-González G, Enríquez JA, Gómez-Cabrera MC
Proceedings of the National Academy of Sciences of the United States of America 2026 Apr 7;123(14):e2508286123
Proceedings of the National Academy of Sciences of the United States of America 2026 Apr 7;123(14):e2508286123
Loss of STARD7 Impairs Mitochondrial Phospholipid Homeostasis and Contributes to Mitochondrial Myopathy.
Horibata Y, Sato T, Ohyama M, Yuyama S, Itoh M, Miura S, Konishi A, Sugimoto H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71777
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71777
Exercise induces sex-specific assembly of mitochondrial supercomplexes.
Huertas JR, Aragón-Vela J, Breenfeldt Andersen A, Bejder J, Nybo L, Nordsborg NB, Rodríguez-Carrillo A, Enriquez JA, Cogliati S, Casuso RA
Cell reports 2026 Apr 3;45(4):117217
Cell reports 2026 Apr 3;45(4):117217
Spatiotemporal controlled release of YCM/Cu(2)⁺ hydrogel microneedle system synergistically accelerates chronic wound healing in diabetes.
Zhang M, Pang Q, Wang Q, Zhong Z, Yin Q, Gao M, Zhang X, Xie S
Journal of nanobiotechnology 2026 Apr 14;
Journal of nanobiotechnology 2026 Apr 14;
Comparative Proteomic Profiling of Microdissected Spindle and Epithelioid Uveal Melanoma Subtypes.
Luan Y, Tang J, Zhu T, Gu X, Chen Y, Wu P, Ding X, Yang L, Ye L, Zhang W, Zhuang A, Jia R, Chai P, Fan X
Investigative ophthalmology & visual science 2026 Apr 1;67(4):32
Investigative ophthalmology & visual science 2026 Apr 1;67(4):32
Hexokinase-2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis Through Metabolic Reprogramming.
Jiang D, Sun Y, Yu X, Wang R, Zhang Y, Yu J, Xie S, Cai Y, Luo Y, Chen W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e03690
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e03690
Gut microbiota modified by Mulberry leaf water extract improves T2DM through browning of WAT/BAT activation mediated by SCFAs-AMPK/SIRT1/PGC-1α signaling pathway.
Du Y, He C, An Y, Zhao Y, Zhang H, Shan Z, Yang Y, Wang M, Xie J, Huang Y, Fu W, Yuan Y, Zhao B
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120408
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120408
C19orf12 inhibits mitochondrial function and enhances the antitumor effects of metformin in non-small cell lung cancer.
Liu R, Zhao M, Zhang X, Wu H, Ren L, Lv J, Liu Z, Wang Q, Yao Z
Cell reports 2025 Sep 23;44(9):116163
Cell reports 2025 Sep 23;44(9):116163
Mdivi-1 promotes steroidogenesis in granulosa cells by inhibiting mitochondrial fission.
He Y, Li X, Kuai D, Zhang H, Wang Y, Wang K, Tian W
Molecular and cellular endocrinology 2025 Sep 15;607:112606
Molecular and cellular endocrinology 2025 Sep 15;607:112606
A galacturonan from sea buckthorn (Hippophae rhamnoides L.) berry modulates dyslipidemia by promoting hepatic lipolysis and mitochondrial oxidation.
Sun Y, Ni W, Wang D, Ren J, Zhao D, Yu S, Liu S, Zhang S, Wang S, Wang W, Liu M
Carbohydrate polymers 2025 Sep 1;363:123708
Carbohydrate polymers 2025 Sep 1;363:123708
Preconception paternal exposure to zearalenone impairs male fertility and IVF embryo survival in mice.
Wang P, Chen Y, Jiao Y, Zhu Y, Wang M, Ji D, Zou W, Cao Y, Liu Y, Liang D
Chemico-biological interactions 2025 Oct 22;420:111646
Chemico-biological interactions 2025 Oct 22;420:111646
Iron accumulation in hypothalamus promotes age-dependent obesity and metabolic dysfunction of male mice.
Wang X, Xiong X, Xuan Y, Tian W, Chen L, Chen Z, Zhang Y, Shen WL, Hu C
Molecular biomedicine 2025 Oct 2;6(1):75
Molecular biomedicine 2025 Oct 2;6(1):75
TRAP1 inhibits KANSL3 acetylation to alleviate mitochondrial dysfunction by promoting mitophagy in cardiomyocytes under diabetic conditions.
Zhang X, Cheng S, Li W, Xu X, Huang X, Chen Z, Li Q, Huang W, Zhang L, Ouyang M
Cell communication and signaling : CCS 2025 Oct 2;23(1):414
Cell communication and signaling : CCS 2025 Oct 2;23(1):414
FXR suppress Müller cell activation by regulating cGAS/STING pathway in diabetic retinopathy.
Wang ZL, Zhang XY, Tan CY, Zhuang M, Zhu L, Zheng XH, Yao Y, Wei TT
The FEBS journal 2025 Nov;292(22):6035-6053
The FEBS journal 2025 Nov;292(22):6035-6053
Targeting LARP1 to mitigate aging in lens epithelial cells: mechanistic insights into mitochondrial dysfunction.
Qi H, Sun L, Chai J, Ma J, Yu H, Xia M, Hu X
Experimental eye research 2025 Nov;260:110582
Experimental eye research 2025 Nov;260:110582
Regulatory role of sirtuin-1 by targeting MDM2 to mitochondria-associated membranes formation in the treatment of NAFLD.
Zhang R, Zhang Q, Cui Z, Huang B, Li M, Ma H
Cell communication and signaling : CCS 2025 Nov 28;23(1):514
Cell communication and signaling : CCS 2025 Nov 28;23(1):514
CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology.
Liao SC, Kano K, Phanse S, Nguyen M, Margolis E, Fu Y, X Meng J, Moutaoufik MT, Chatterton Z, Saccon T, Broderick K, Aoki H, Simms J, Suteja FX, Sei Y, Huang EJ, McAvoy K, Manfredi G, Halliday G, Babu M, Nakamura K
Science advances 2025 Nov 14;11(46):eadu0726
Science advances 2025 Nov 14;11(46):eadu0726
P-Type Pentatricopeptide Repeat Proteins YS1 and YS2 Function in Splicing of petB Intron to Maintain Chloroplast Homeostasis During Rice Seedling Development.
Sun H, Nie Y, Yu L, Yue X, Hou X, Zhao J
International journal of molecular sciences 2025 May 7;26(9)
International journal of molecular sciences 2025 May 7;26(9)
Selenoprotein K Confers Protection against Iron Dyshomeostasis-Related Neurotoxicity by Regulating the Palmitoylation of TfR-1.
Jia SZ, Li Y, Xu XW, Huang YP, Deng XY, Zhang ZH, Song GL
Journal of agricultural and food chemistry 2025 May 21;73(20):12233-12246
Journal of agricultural and food chemistry 2025 May 21;73(20):12233-12246
Targeting mitochondrial complex I of CD177(+) neutrophils alleviates lung ischemia-reperfusion injury.
Wu J, Gao P, Yang C, Zhuang F, Luo Y, Wen F, Zhang P, Wang L, Xie H, Dai C, Zhao D, Li C, Deng H, Deng Z, Chen C
Cell reports. Medicine 2025 May 20;6(5):102140
Cell reports. Medicine 2025 May 20;6(5):102140
Effects of polystyrene microparticles exposures on spermatogenic cell differentiation and reproductive endpoints in male mice.
Shen R, Xia P, Guo Y, Ji P, Yuan X, Wang L, Shuang S, Zhou L, Tong R, Zhang L, Liu D, Wang D
Environmental pollution (Barking, Essex : 1987) 2025 May 15;373:126200
Environmental pollution (Barking, Essex : 1987) 2025 May 15;373:126200
Isolated Mitochondrial Transplantation as a Novel Treatment for Corneal Chemical Burns.
Jiang D, Yu J, Wu X, Yu X, Jin P, Zheng H, Liu H, Xu W, Lian Q, Chen W
Investigative ophthalmology & visual science 2025 Mar 3;66(3):14
Investigative ophthalmology & visual science 2025 Mar 3;66(3):14
Neurotoxicity of Realgar: Crosstalk Between UBXD8-DRP1-Regulated Mitochondrial Fission and PINK1-Parkin-Mediated Mitophagy.
Feng R, Liu J, Yao T, Yang Z, Jiang H
Molecular neurobiology 2025 Jun;62(6):7041-7053
Molecular neurobiology 2025 Jun;62(6):7041-7053
Peptide YY fragment PYY1-36 disrupts mitochondrial biogenesis via RBM43-dependent PGC-1α translation inhibition.
Liu B, Zhou F, Shi B, Yan Y, Wang Y, Wang J, Lang Y, Xu S
Investigational new drugs 2025 Jun;43(3):669-678
Investigational new drugs 2025 Jun;43(3):669-678
The crucial function of IDO1 in pulmonary fibrosis: From the perspective of mitochondrial fusion in lung fibroblasts and targeted molecular inhibition.
Wang L, Ge S, Zhang Y, Feng D, Zhu T, Zhang L, Zhang C
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3125-3148
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3125-3148
Corticosterone induces fatty liver syndrome in chickens via glucocorticoid receptor and inhibition of mitochondrial supercomplex formation.
Chen H, Zhang K, Yu H, Guan Z, Zhao R, Wu L
American journal of physiology. Regulatory, integrative and comparative physiology 2025 Jun 1;328(6):R770-R782
American journal of physiology. Regulatory, integrative and comparative physiology 2025 Jun 1;328(6):R770-R782
hUC-MSC preserves erectile function by restoring mitochondrial mass of penile smooth muscle cells in a rat model of cavernous nerve injury via SIRT1/PGC-1a/TFAM signaling.
Yang M, Chen X, Zhang M, Zhang X, Xiao D, Xu H, Lu M
Biological research 2025 Jan 27;58(1):8
Biological research 2025 Jan 27;58(1):8
CISD2-mediated mitochondrial dysfunction and iron redistribution contributes to ferroptosis in arsenic-induced nonalcoholic steatohepatitis.
Zhang J, Wang L, Lu Y, Zheng F, Ding X, Yao X, Bai J, Wang N, Yang G, Qiu T, Sun X
Ecotoxicology and environmental safety 2025 Jan 1;289:117694
Ecotoxicology and environmental safety 2025 Jan 1;289:117694
Triptolide exposure triggers ovarian inflammation by activating cGAS-STING pathway and decrease oocyte quality in mouse.
Cheng SY, Yang YF, Wang YL, Yue ZP, Chen YZ, Wang WK, Xu ZR, Li LF, Shen H, Qi ZM, Xu CL, Liu Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Feb;196:115201
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Feb;196:115201
Aptamer-Conjugated Exosomes Ameliorate Diabetes-Induced Muscle Atrophy by Enhancing SIRT1/FoxO1/3a-Mediated Mitochondrial Function.
Song J, Yang M, Xia L, Wang L, Wang K, Xiang Y, Cheng J, Chen J, Liu J, Zhao R, Liu F, Sun Z, Hou X, Zang N, Chen L
Journal of cachexia, sarcopenia and muscle 2025 Feb;16(1):e13717
Journal of cachexia, sarcopenia and muscle 2025 Feb;16(1):e13717
CRIP1 inhibits cutaneous melanoma progression through TFAM-mediated mitochondrial biogenesis.
Wu J, Chen L, Wen P
Scientific reports 2025 Feb 4;15(1):4298
Scientific reports 2025 Feb 4;15(1):4298
Qihuang Zhuyu formula modulates mitochondrial function to inhibit platelet activation via endocannabinoid signaling mediated by the SIRT1/PPARα pathway.
Shi R, Sun W, Yin S, Sun T, Yang N, Zhang H, Yao Y, Lai K, Chen X, Yu P
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119006
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119006
MDPAO1 peptide from human milk enhances brown adipose tissue thermogenesis and mitigates obesity.
Gao Y, Zhang J, Cao M, Zhang Y, Cao M, Gu W, Wang M
Molecular and cellular endocrinology 2025 Feb 1;597:112443
Molecular and cellular endocrinology 2025 Feb 1;597:112443
CD147 mitochondria translocation induced airway remodeling in asthmatic mouse models by regulating M2 macrophage polarization via ANT1-mediated mitophagy.
Zhu G, Yu H, Li X, Ye W, Chen X, Gu W
American journal of physiology. Cell physiology 2025 Feb 1;328(2):C604-C616
American journal of physiology. Cell physiology 2025 Feb 1;328(2):C604-C616
NAD(+) Enhanced Mesenchymal Stromal Cells Effect on Muscle Atrophy by Improving SIRT1-Mediated Mitochondrial Function via NAMPT.
Song J, Sun Y, Zang N, Liu X, Chen J, Wang K, Xia L, Chen J, Zhao R, Liu F, Hou X, Chen L, Cheng J, Zhang W
Journal of cachexia, sarcopenia and muscle 2025 Dec;16(6):e70142
Journal of cachexia, sarcopenia and muscle 2025 Dec;16(6):e70142
Sexual dimorphism on the acute effect of exercise in the morning vs. evening: A randomized crossover study.
Sevilla-Lorente R, Marmol-Perez A, Gonzalez-Garcia P, Rodríguez-Miranda MLN, Riquelme-Gallego B, Aragon-Vela J, Martinez-Gálvez JM, Molina-Garcia P, Alcantara JMA, Garcia-Consuegra J, Cogliati S, Salmeron LM, Huertas JR, Lopez LC, Ruiz JR, Amaro-Gahete FJ
Journal of sport and health science 2025 Dec;14:101021
Journal of sport and health science 2025 Dec;14:101021
Kaempferol exerts anti-colorectal cancer effects through its multi-target mediated glucose metabolism remodeling.
Wu H, Guo Z, Hu P, Du J, Wang P, Ma J, Zhao B, Wei J, Li Z
Food & function 2025 Dec 8;16(24):9593-9608
Food & function 2025 Dec 8;16(24):9593-9608
Defective vascular smooth muscle cell tafazzin impairs mitochondrial function and promotes atherosclerosis in preclinical models.
Dong C, Finigan A, Figg N, Jenkins B, Koulman A, Chowdhury SR, Tricolici AM, Lambert J, Oc S, Jørgensen HF, Prudent J, Murphy MP, Bennett M, Yu E
Nature communications 2025 Dec 4;16(1):10909
Nature communications 2025 Dec 4;16(1):10909
Darunavir analog precursors target mitochondrial metabolism in multiple myeloma and CLL.
Mecca M, Sichetti M, Spina E, Giuseffi M, Giglio E, Picerno S, Valvano L, Statuto T, Santarsiere A, Funicello M, Armentano MF, Chiummiento L, Lupattelli P, Romano A, Giordano A, Cortellino S
Cancer cell international 2025 Dec 23;26(1):44
Cancer cell international 2025 Dec 23;26(1):44
Liraglutide alleviates diabetic cardiomyopathy in streptozotocin-induced diabetic rats by enhancing mitophagy mediated by the AMPK-Parkin signaling pathway.
Zhu YX, Zhang W, Qu HL, Zhang Y, Zhou RQ, Li P, Wang F, Zhang Y, Liu HH, Li S, Dong Q, Dou KF, Guo YL, Li JJ, Xu RX
World journal of diabetes 2025 Dec 15;16(12):112423
World journal of diabetes 2025 Dec 15;16(12):112423
CX3CL1 deficiency ameliorates acute kidney injury by inhibiting macrophage mitochondrial dysfunction and mtDNA-cGAS-STING signaling.
Gong Q, Liu F, Huang Y, Li D, Zhou T, Zeng C, Jiang Y, Wei H, Xu Y
Cell death discovery 2025 Dec 13;12(1):69
Cell death discovery 2025 Dec 13;12(1):69
Markers of mitochondrial function and oxidative metabolism in skeletal muscle do not display intrinsic circadian regulation in female mice.
Fitzgerald LS, Reynoso Spurrier CS, Lau NJ, Melamed MD, Burnett LA, Meyer GA, Gui C, Hevener AL, Sanford JA, Schenk S
American journal of physiology. Endocrinology and metabolism 2025 Dec 1;329(6):E828-E838
American journal of physiology. Endocrinology and metabolism 2025 Dec 1;329(6):E828-E838
Downhill running induced mitophagy in rat soleus muscle via the AMPK pathway.
Shang H, Ma R, Chen S, Deng H, Li M, Zheng S, Zhang H, Zhang D, Yang T, Yang Y, Xia Z
Journal of physiology and biochemistry 2025 Aug;81(3):673-685
Journal of physiology and biochemistry 2025 Aug;81(3):673-685
HIF-1α mediates mitochondrial damage by down-regulating ALKBH7 expression to promote the aberrant activation of FLS in rheumatoid arthritis.
Wang H, Zhao YC, Xu L, Zhang TJ, Liu LH, Zhou MQ, Zhang H, Yang YN, Pan P, Jin L, Zhang ZW, Zhang XZ, Zhang LL
Acta pharmacologica Sinica 2025 Aug;46(8):2225-2236
Acta pharmacologica Sinica 2025 Aug;46(8):2225-2236
Supercomplex Restructuring in Heart Mitochondria of COX7A1-Deficient Mice.
Pavelich L, Pham L, Stemmer P, Lee I, Grossman LI, Hüttemann M, Arroum T
Biomolecules 2025 Aug 22;15(9)
Biomolecules 2025 Aug 22;15(9)
A robust method for assessing mitochondrial function in healthy and diseased frozen cardiac tissue.
Hu L, van Rinsum A, Caliandro R, Qi X, Fan S, Jiang X, Massop J, Bekkenkamp-Grovenstein M, Ott C, Grune T, van de Wal MAE, Koopman WJH, Giesbers M, Gladka M, Keijer J, Zhang D
Communications biology 2025 Aug 19;8(1):1249
Communications biology 2025 Aug 19;8(1):1249
Clioquinol induces mitochondrial toxicity in SH-SY5Y neuroblastoma cells by affecting the respiratory chain complex IV and OPA1 dynamin-like GTPase.
Katsuyama M, Arakawa N, Yaoi T, Kimura E, Matsumoto M, Iwata K, Umemura A, Yabe-Nishimura C
FEBS letters 2025 Apr;599(8):1135-1145
FEBS letters 2025 Apr;599(8):1135-1145
Idebenone improves mitochondrial respiratory activity and attenuates oxidative damage via the SIRT3-SOD2 pathway in a prion disease cell model.
Sun Z, Wen P, Yang D, Li J, Li Z, Zhao M, Wang D, Gou F, Wang J, Fan Q, Dai Y, Ji Y, Li X, Tu Y, Ma T, Wang X, Zhao D, Yang L
Life sciences 2025 Apr 1;366-367:123481
Life sciences 2025 Apr 1;366-367:123481
Xiasangju alleviate metabolic syndrome by enhancing noradrenaline biosynthesis and activating brown adipose tissue.
He C, An Y, Shi L, Huang Y, Zhang H, Fu W, Wang M, Shan Z, Du Y, Xie J, Huang Z, Sun W, Zhao Y, Zhao B
Frontiers in pharmacology 2024;15:1371929
Frontiers in pharmacology 2024;15:1371929
Nucleophosmin 1 promotes mucosal immunity by supporting mitochondrial oxidative phosphorylation and ILC3 activity.
Zhao R, Yang J, Zhai Y, Zhang H, Zhou Y, Hong L, Yuan D, Xia R, Liu Y, Pan J, Shafi S, Shi G, Zhang R, Luo D, Yuan J, Pan D, Peng C, Li S, Sun M
Nature immunology 2024 Sep;25(9):1565-1579
Nature immunology 2024 Sep;25(9):1565-1579
Early heart and skeletal muscle mitochondrial response to a moderate hypobaric hypoxia environment.
Aragón-Vela J, Casuso RA, Aparisi AS, Plaza-Díaz J, Rueda-Robles A, Hidalgo-Gutiérrez A, López LC, Rodríguez-Carrillo A, Enriquez JA, Cogliati S, Huertas JR
The Journal of physiology 2024 Nov;602(21):5631-5641
The Journal of physiology 2024 Nov;602(21):5631-5641
Acrylamide Exposure Impairs Ovarian Tricarboxylic Acid Cycle and Reduces Oocyte Quality in Mouse.
Liu YC, Li RC, Wang WK, Chen YZ, He QK, Xu ZR, Yang YF, Cheng SY, Wang HL, Qi ZQ, Xu CL, Liu Y
Environmental toxicology 2024 Nov;39(11):5074-5085
Environmental toxicology 2024 Nov;39(11):5074-5085
Integrated analyses of multi-omic data derived from paired primary lung cancer and brain metastasis reveal the metabolic vulnerability as a novel therapeutic target.
Duan H, Ren J, Wei S, Yang Z, Li C, Wang Z, Li M, Wei Z, Liu Y, Wang X, Lan H, Zeng Z, Xie M, Xie Y, Wu S, Hu W, Guo C, Zhang X, Liang L, Yu C, Mou Y, Jiang Y, Li H, Sugarman E, Deek RA, Chen Z, Li T, Chen Y, Yao M, Chen L, Liu L, Zhang G, Mou Y
Genome medicine 2024 Nov 26;16(1):138
Genome medicine 2024 Nov 26;16(1):138
A transmitochondrial sodium gradient controls membrane potential in mammalian mitochondria.
Hernansanz-Agustín P, Morales-Vidal C, Calvo E, Natale P, Martí-Mateos Y, Jaroszewicz SN, Cabrera-Alarcón JL, Acín-Pérez R, López-Montero I, Vázquez J, Enríquez JA
Cell 2024 Nov 14;187(23):6599-6613.e21
Cell 2024 Nov 14;187(23):6599-6613.e21
Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway.
Miao ZF, Sun JX, Huang XZ, Bai S, Pang MJ, Li JY, Chen HY, Tong QY, Ye SY, Wang XY, Hu XH, Li JY, Zou JW, Xu W, Yang JH, Lu X, Mills JC, Wang ZN
Developmental cell 2024 May 6;59(9):1175-1191.e7
Developmental cell 2024 May 6;59(9):1175-1191.e7
Defective mitochondria remodelling in B cells leads to an aged immune response.
Iborra-Pernichi M, Ruiz García J, Velasco de la Esperanza M, Estrada BS, Bovolenta ER, Cifuentes C, Prieto Carro C, González Martínez T, García-Consuegra J, Rey-Stolle MF, Rupérez FJ, Guerra Rodriguez M, Argüello RJ, Cogliati S, Martín-Belmonte F, Martínez-Martín N
Nature communications 2024 Mar 22;15(1):2569
Nature communications 2024 Mar 22;15(1):2569
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
Huang W, Wang L, Huang Z, Sun Z, Zheng B
Respiratory research 2024 Mar 2;25(1):110
Respiratory research 2024 Mar 2;25(1):110
Nmnat1 Deficiency Causes Mitoribosome Excess in Diabetic Nephropathy Mediated by Transcriptional Repressor HIC1.
Hasegawa K, Tamaki M, Sakamaki Y, Wakino S
International journal of molecular sciences 2024 Jun 9;25(12)
International journal of molecular sciences 2024 Jun 9;25(12)
Redistribution of defective mitochondria-mediated dihydroorotate dehydrogenase imparts 5-fluorouracil resistance in colorectal cancer.
Dong S, Zhang M, Cheng Z, Zhang X, Liang W, Li S, Li L, Xu Q, Song S, Liu Z, Yang G, Zhao X, Tao Z, Liang S, Wang K, Zhang G, Hu S
Redox biology 2024 Jul;73:103207
Redox biology 2024 Jul;73:103207
SCAF1 drives the compositional diversity of mammalian respirasomes.
Vercellino I, Sazanov LA
Nature structural & molecular biology 2024 Jul;31(7):1061-1071
Nature structural & molecular biology 2024 Jul;31(7):1061-1071
Cox7a1 controls skeletal muscle physiology and heart regeneration through complex IV dimerization.
García-Poyatos C, Arora P, Calvo E, Marques IJ, Kirschke N, Galardi-Castilla M, Lembke C, Meer M, Fernández-Montes P, Ernst A, Haberthür D, Hlushchuk R, Vázquez J, Vermathen P, Enríquez JA, Mercader N
Developmental cell 2024 Jul 22;59(14):1824-1841.e10
Developmental cell 2024 Jul 22;59(14):1824-1841.e10
Radiation-induced changes in energy metabolism result in mitochondrial dysfunction in salivary glands.
Buss LG, Rheinheimer BA, Limesand KH
Scientific reports 2024 Jan 8;14(1):845
Scientific reports 2024 Jan 8;14(1):845
Mic19 depletion impairs endoplasmic reticulum-mitochondrial contacts and mitochondrial lipid metabolism and triggers liver disease.
Dong J, Chen L, Ye F, Tang J, Liu B, Lin J, Zhou PH, Lu B, Wu M, Lu JH, He JJ, Engelender S, Meng Q, Song Z, He H
Nature communications 2024 Jan 2;15(1):168
Nature communications 2024 Jan 2;15(1):168
Mitochondria isolated from lipid droplets of white adipose tissue reveal functional differences based on lipid droplet size.
Brownstein AJ, Veliova M, Acin-Perez R, Villalobos F, Petcherski A, Tombolato A, Liesa M, Shirihai OS
Life science alliance 2024 Feb;7(2)
Life science alliance 2024 Feb;7(2)
AMPK phosphorylation of FNIP1 (S220) controls mitochondrial function and muscle fuel utilization during exercise.
Xiao L, Yin Y, Sun Z, Liu J, Jia Y, Yang L, Mao Y, Peng S, Xie Z, Fang L, Li J, Xie X, Gan Z
Science advances 2024 Feb 9;10(6):eadj2752
Science advances 2024 Feb 9;10(6):eadj2752
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis.
He Y, Zhu G, Li X, Zhou M, Guan MX
iScience 2024 Feb 16;27(2):108883
iScience 2024 Feb 16;27(2):108883
CHCHD10(P80L) knock-in zebrafish display a mild ALS-like phenotype.
Petel Légaré V, Harji ZA, Rampal CJ, Antonicka H, Gurberg TJN, Persia O, Rodríguez EC, Shoubridge EA, Armstrong GAB
Experimental neurology 2024 Dec;382:114945
Experimental neurology 2024 Dec;382:114945
KARS Mutations Impair Brain Myelination by Inducing Oligodendrocyte Deficiency: One Potential Mechanism and Improvement by Melatonin.
Yu L, Chen Z, Zhou X, Teng F, Bai QR, Li L, Li Y, Liu Y, Zeng Q, Wang Y, Wang M, Xu Y, Tang X, Wang X
Journal of pineal research 2024 Aug;76(5):e12998
Journal of pineal research 2024 Aug;76(5):e12998
Lysosomes drive the piecemeal removal of mitochondrial inner membrane.
Prashar A, Bussi C, Fearns A, Capurro MI, Gao X, Sesaki H, Gutierrez MG, Jones NL
Nature 2024 Aug;632(8027):1110-1117
Nature 2024 Aug;632(8027):1110-1117
Mitochondrial translation is the primary determinant of secondary mitochondrial complex I deficiencies.
Čunátová K, Vrbacký M, Puertas-Frias G, Alán L, Vanišová M, Saucedo-Rodríguez MJ, Houštěk J, Fernández-Vizarra E, Neužil J, Pecinová A, Pecina P, Mráček T
iScience 2024 Aug 16;27(8):110560
iScience 2024 Aug 16;27(8):110560
Mesenchymal stromal cells ameliorate mitochondrial dysfunction in α cells and hyperglucagonemia in type 2 diabetes via SIRT1/FoxO3a signaling.
Song J, Wang L, Wang L, Guo X, He Q, Cui C, Hu H, Zang N, Yang M, Yan F, Liang K, Wang C, Liu F, Sun Y, Sun Z, Lai H, Hou X, Chen L
Stem cells translational medicine 2024 Aug 16;13(8):776-790
Stem cells translational medicine 2024 Aug 16;13(8):776-790
Mitochondria-mediated ferroptosis induced by CARD9 ablation prevents MDSCs-dependent antifungal immunity.
Zhang Z, Li P, Chen Y, Chen Y, Wang X, Shen S, Zhao Y, Zhu Y, Wang T
Cell communication and signaling : CCS 2024 Apr 2;22(1):210
Cell communication and signaling : CCS 2024 Apr 2;22(1):210
Aerobic exercise enhances mitochondrial homeostasis to counteract D-galactose-induced sarcopenia in zebrafish.
Chen ZL, Guo C, Zou YY, Feng C, Yang DX, Sun CC, Wen W, Jian ZJ, Zhao Z, Xiao Q, Zheng L, Peng XY, Zhou ZQ, Tang CF
Experimental gerontology 2023 Sep;180:112265
Experimental gerontology 2023 Sep;180:112265
Oat β-D-glucan ameliorates type II diabetes through TLR4/PI3K/AKT mediated metabolic axis.
Guo H, Wu H, Hou Y, Hu P, Du J, Cao L, Yang R, Dong X, Li Z
International journal of biological macromolecules 2023 Sep 30;249:126039
International journal of biological macromolecules 2023 Sep 30;249:126039
TGR5 supresses cGAS/STING pathway by inhibiting GRP75-mediated endoplasmic reticulum-mitochondrial coupling in diabetic retinopathy.
Li Y, Zhu L, Cai MX, Wang ZL, Zhuang M, Tan CY, Xie TH, Yao Y, Wei TT
Cell death & disease 2023 Sep 1;14(9):583
Cell death & disease 2023 Sep 1;14(9):583
A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation.
Palermo A, Li S, Ten Hoeve J, Chellappa A, Morris A, Dillon B, Ma F, Wang Y, Cao E, Shabane B, Acín-Perez R, Petcherski A, Lusis AJ, Hazen S, Shirihai OS, Pellegrini M, Arumugaswami V, Graeber TG, Deb A
Communications biology 2023 Nov 3;6(1):1115
Communications biology 2023 Nov 3;6(1):1115
Radiation-Induced Changes in Energy Metabolism Result in Mitochondrial Dysfunction in Salivary Glands.
Buss LG, Rheinheimer BA, Limesand KH
bioRxiv : the preprint server for biology 2023 Nov 27;
bioRxiv : the preprint server for biology 2023 Nov 27;
Iron derived from NCOA4-mediated ferritinophagy causes cellular senescence via the cGAS-STING pathway.
Li HY, Wei TT, Zhuang M, Tan CY, Xie TH, Cai J, Yao Y, Zhu L
Cell death discovery 2023 Nov 18;9(1):419
Cell death discovery 2023 Nov 18;9(1):419
FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.
Wu J, Subbaiah KCV, Hedaya O, Chen S, Munger J, Tang WHW, Yan C, Yao P
bioRxiv : the preprint server for biology 2023 May 22;
bioRxiv : the preprint server for biology 2023 May 22;
Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies.
Acin-Perez R, Benincá C, Fernandez Del Rio L, Shu C, Baghdasarian S, Zanette V, Gerle C, Jiko C, Khairallah R, Khan S, Rincon Fernandez Pacheco D, Shabane B, Erion K, Masand R, Dugar S, Ghenoiu C, Schreiner G, Stiles L, Liesa M, Shirihai OS
The EMBO journal 2023 May 15;42(10):e111699
The EMBO journal 2023 May 15;42(10):e111699
Impairment of adrenergically-regulated thermogenesis in brown fat of obesity-resistant mice is compensated by non-shivering thermogenesis in skeletal muscle.
Janovska P, Zouhar P, Bardova K, Otahal J, Vrbacky M, Mracek T, Adamcova K, Lenkova L, Funda J, Cajka T, Drahota Z, Stanic S, Rustan AC, Horakova O, Houstek J, Rossmeisl M, Kopecky J
Molecular metabolism 2023 Mar;69:101683
Molecular metabolism 2023 Mar;69:101683
The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.
Lavie J, Lalou C, Mahfouf W, Dupuy JW, Lacaule A, Cywinska AA, Lacombe D, Duchêne AM, Raymond AA, Rezvani HR, Ngondo RP, Bénard G
Cell reports 2023 Jun 27;42(6):112579
Cell reports 2023 Jun 27;42(6):112579
5-HEPE reduces obesity and insulin resistance by promoting adipose tissue browning through GPR119/AMPK/PGC1α activation.
Zong Y, Wang M, Liu Y, Suo X, Fan G, Yang X
Life sciences 2023 Jun 15;323:121703
Life sciences 2023 Jun 15;323:121703
A high-fat diet increases hepatic mitochondrial turnover through restricted acetylation in a NAFLD mouse model.
Aghayev M, Arias-Alvarado A, Ilchenko S, Lepp J, Scott I, Chen YR, Zhang GF, Tsai TH, Kasumov T
American journal of physiology. Endocrinology and metabolism 2023 Jul 1;325(1):E83-E98
American journal of physiology. Endocrinology and metabolism 2023 Jul 1;325(1):E83-E98
Loss of mitochondrial Chchd10 or Chchd2 in zebrafish leads to an ALS-like phenotype and Complex I deficiency independent of the mitochondrial integrated stress response.
Petel Légaré V, Rampal CJ, Gurberg TJN, Aaltonen MJ, Janer A, Zinman L, Shoubridge EA, Armstrong GAB
Developmental neurobiology 2023 Jan;83(1-2):54-69
Developmental neurobiology 2023 Jan;83(1-2):54-69
Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle.
Ouyang Q, Chen Q, Ke S, Ding L, Yang X, Rong P, Feng W, Cao Y, Wang Q, Li M, Su S, Wei W, Liu M, Liu J, Zhang X, Li JZ, Wang HY, Chen S
Developmental cell 2023 Feb 27;58(4):289-305.e6
Developmental cell 2023 Feb 27;58(4):289-305.e6
Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1.
Tong L, Rao J, Yang C, Xu J, Lu Y, Zhang Y, Cang X, Xie S, Mao J, Jiang P
iScience 2023 Aug 18;26(8):107446
iScience 2023 Aug 18;26(8):107446
Aristolochic acid I exposure triggers ovarian dysfunction by activating NLRP3 inflammasome and affecting mitochondrial homeostasis.
Sun MX, Qiao FX, Xu ZR, Liu YC, Xu CL, Wang HL, Qi ZQ, Liu Y
Free radical biology & medicine 2023 Aug 1;204:313-324
Free radical biology & medicine 2023 Aug 1;204:313-324
Diosgenin Inhibits ROS Generation by Modulating NOX4 and Mitochondrial Respiratory Chain and Suppresses Apoptosis in Diabetic Nephropathy.
Zhong Y, Wang L, Jin R, Liu J, Luo R, Zhang Y, Zhu L, Peng X
Nutrients 2023 Apr 30;15(9)
Nutrients 2023 Apr 30;15(9)
Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats.
Li S, Dong S, Xu Q, Shi B, Li L, Zhang W, Zhu J, Cheng Y, Zhang G, Zhong M
Frontiers in physiology 2022;13:837798
Frontiers in physiology 2022;13:837798
Oncometabolite d-2HG alters T cell metabolism to impair CD8(+) T cell function.
Notarangelo G, Spinelli JB, Perez EM, Baker GJ, Kurmi K, Elia I, Stopka SA, Baquer G, Lin JR, Golby AJ, Joshi S, Baron HF, Drijvers JM, Georgiev P, Ringel AE, Zaganjor E, McBrayer SK, Sorger PK, Sharpe AH, Wucherpfennig KW, Santagata S, Agar NYR, Suvà ML, Haigis MC
Science (New York, N.Y.) 2022 Sep 30;377(6614):1519-1529
Science (New York, N.Y.) 2022 Sep 30;377(6614):1519-1529
Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene.
Novakova Z, Milosevic M, Kutil Z, Ondrakova M, Havlinova B, Kasparek P, Sandoval-Acuña C, Korandova Z, Truksa J, Vrbacky M, Rohlena J, Barinka C
Scientific reports 2022 Oct 12;12(1):17081
Scientific reports 2022 Oct 12;12(1):17081
FNIP1 regulates adipocyte browning and systemic glucose homeostasis in mice by shaping intracellular calcium dynamics.
Yin Y, Xu D, Mao Y, Xiao L, Sun Z, Liu J, Zhou D, Xu Z, Liu L, Fu T, Ding C, Guo Q, Sun W, Zhou Z, Yang L, Jia Y, Chen X, Gan Z
The Journal of experimental medicine 2022 May 2;219(5)
The Journal of experimental medicine 2022 May 2;219(5)
Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.
Shen R, Yang K, Cheng X, Guo C, Xing X, Sun H, Liu D, Liu X, Wang D
Environmental pollution (Barking, Essex : 1987) 2022 May 1;300:118986
Environmental pollution (Barking, Essex : 1987) 2022 May 1;300:118986
Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I.
Jain S, Hu C, Kluza J, Ke W, Tian G, Giurgiu M, Bleilevens A, Campos AR, Charbono A, Stickeler E, Maurer J, Holinski-Feder E, Vaisburg A, Bureik M, Luo G, Marchetti P, Cheng Y, Wolf DA
Cell chemical biology 2022 Mar 17;29(3):436-450.e15
Cell chemical biology 2022 Mar 17;29(3):436-450.e15
LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Zhao K, Huang X, Zhao W, Lu B, Yang Z
Development (Cambridge, England) 2022 Mar 15;149(6)
Development (Cambridge, England) 2022 Mar 15;149(6)
MDH2 produced OAA is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle.
Molinié T, Cougouilles E, David C, Cahoreau E, Portais JC, Mourier A
Biochimica et biophysica acta. Bioenergetics 2022 Mar 1;1863(3):148532
Biochimica et biophysica acta. Bioenergetics 2022 Mar 1;1863(3):148532
Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4.
Guo Q, Xu Z, Zhou D, Fu T, Wang W, Sun W, Xiao L, Liu L, Ding C, Yin Y, Zhou Z, Sun Z, Zhu Y, Zhou W, Jia Y, Xue J, Chen Y, Chen XW, Piao HL, Lu B, Gan Z
Science advances 2022 Jul 29;8(30):eabo0340
Science advances 2022 Jul 29;8(30):eabo0340
Slc25a5 regulates adipogenesis by modulating ERK signaling in OP9 cells.
Zhu S, Wang W, Zhang J, Ji S, Jing Z, Chen YQ
Cellular & molecular biology letters 2022 Feb 2;27(1):11
Cellular & molecular biology letters 2022 Feb 2;27(1):11
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
Xu Z, Fu T, Guo Q, Zhou D, Sun W, Zhou Z, Chen X, Zhang J, Liu L, Xiao L, Yin Y, Jia Y, Pang E, Chen Y, Pan X, Fang L, Zhu MS, Fei W, Lu B, Gan Z
Nature communications 2022 Feb 16;13(1):894
Nature communications 2022 Feb 16;13(1):894
The Absence of Parkin Does Not Promote Dopamine or Mitochondrial Dysfunction in PolgA(D257A/D257A) Mitochondrial Mutator Mice.
Scott L, Karuppagounder SS, Neifert S, Kang BG, Wang H, Dawson VL, Dawson TM
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Dec 7;42(49):9263-9277
The Journal of neuroscience : the official journal of the Society for Neuroscience 2022 Dec 7;42(49):9263-9277
Biochanin A Inhibits Glioblastoma Growth via Restricting Glycolysis and Mitochondrial Oxidative Phosphorylation.
Dong Q, Li Q, Duan L, Yin H, Wang X, Liu Y, Wang B, Li K, Yao X, Yuan G, Pan Y
Frontiers in oncology 2021;11:652008
Frontiers in oncology 2021;11:652008
Punicalagin Protects Against Diabetic Cardiomyopathy by Promoting Opa1-Mediated Mitochondrial Fusion via Regulating PTP1B-Stat3 Pathway.
Fu F, Liu C, Shi R, Li M, Zhang M, Du Y, Wang Q, Li J, Wang G, Pei J, Ding M
Antioxidants & redox signaling 2021 Sep;35(8):618-641
Antioxidants & redox signaling 2021 Sep;35(8):618-641
Imatinib Regulates miR-483-3p and Mitochondrial Respiratory Complexes in Gastrointestinal Stromal Tumors.
Huang WK, Shi H, Akçakaya P, Zeljic K, Gangaev A, Caramuta S, Yeh CN, Bränström R, Larsson C, Lui WO
International journal of molecular sciences 2021 Sep 30;22(19)
International journal of molecular sciences 2021 Sep 30;22(19)
Structure and assembly of the mammalian mitochondrial supercomplex CIII(2)CIV.
Vercellino I, Sazanov LA
Nature 2021 Oct;598(7880):364-367
Nature 2021 Oct;598(7880):364-367
Single-cell analysis reveals androgen receptor regulates the ER-to-Golgi trafficking pathway with CREB3L2 to drive prostate cancer progression.
Hu L, Chen X, Narwade N, Lim MGL, Chen Z, Tennakoon C, Guan P, Chan UI, Zhao Z, Deng M, Xu X, Sung WK, Cheung E
Oncogene 2021 Nov;40(47):6479-6493
Oncogene 2021 Nov;40(47):6479-6493
Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2.
Chella Krishnan K, Vergnes L, Acín-Pérez R, Stiles L, Shum M, Ma L, Mouisel E, Pan C, Moore TM, Péterfy M, Romanoski CE, Reue K, Björkegren JLM, Laakso M, Liesa M, Lusis AJ
Nature metabolism 2021 Nov;3(11):1552-1568
Nature metabolism 2021 Nov;3(11):1552-1568
Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.
Le Vasseur M, Friedman J, Jost M, Xu J, Yamada J, Kampmann M, Horlbeck MA, Salemi MR, Phinney BS, Weissman JS, Nunnari J
eLife 2021 May 26;10
eLife 2021 May 26;10
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Shi M, Huang XY, Ren XY, Wei XY, Ma Y, Lin ZZ, Liu DT, Song L, Zhao TJ, Li G, Yao L, Zhu M, Zhang C, Xie C, Wu Y, Wu HM, Fan LP, Ou J, Zhan YH, Lin SY, Lin SC
Nature cell biology 2021 Mar;23(3):268-277
Nature cell biology 2021 Mar;23(3):268-277
AMPK-dependent and -independent coordination of mitochondrial function and muscle fiber type by FNIP1.
Xiao L, Liu J, Sun Z, Yin Y, Mao Y, Xu D, Liu L, Xu Z, Guo Q, Ding C, Sun W, Yang L, Zhou Z, Zhou D, Fu T, Zhou W, Zhu Y, Chen XW, Li JZ, Chen S, Xie X, Gan Z
PLoS genetics 2021 Mar;17(3):e1009488
PLoS genetics 2021 Mar;17(3):e1009488
Predominant cellular mitochondrial dysfunction in the TOP3A gene-caused Bloom syndrome-like disorder.
Jiang W, Jia N, Guo C, Wen J, Wu L, Ogi T, Zhang H
Biochimica et biophysica acta. Molecular basis of disease 2021 Jun 1;1867(6):166106
Biochimica et biophysica acta. Molecular basis of disease 2021 Jun 1;1867(6):166106
OMA1 reprograms metabolism under hypoxia to promote colorectal cancer development.
Wu Z, Zuo M, Zeng L, Cui K, Liu B, Yan C, Chen L, Dong J, Shangguan F, Hu W, He H, Lu B, Song Z
EMBO reports 2021 Jan 7;22(1):e50827
EMBO reports 2021 Jan 7;22(1):e50827
Deficiency of β-carotene oxygenase 2 induces mitochondrial fragmentation and activates the STING-IRF3 pathway in the mouse hypothalamus.
Wu L, Guo X, Wong SY, Lu P, Hartson SD, Medeiros DM, Wang W, Clarke SL, Lucas EA, Smith BJ, Chowanadisai W, Lin D
The Journal of nutritional biochemistry 2021 Feb;88:108542
The Journal of nutritional biochemistry 2021 Feb;88:108542
Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca(2+) Homeostasis, and Bcl2 Expression.
Zhong Y, Jin C, Han J, Zhu J, Liu Q, Sun D, Xia X, Zhang Y, Peng X
Molecular nutrition & food research 2021 Aug;65(15):e2001202
Molecular nutrition & food research 2021 Aug;65(15):e2001202
Analyzing electron transport chain supercomplexes.
Acín-Pérez R, Hernansanz-Agustín P, Enríquez JA
Methods in cell biology 2020;155:181-197
Methods in cell biology 2020;155:181-197
Functional role of respiratory supercomplexes in mice: SCAF1 relevance and segmentation of the Q(pool).
Calvo E, Cogliati S, Hernansanz-Agustín P, Loureiro-López M, Guarás A, Casuso RA, García-Marqués F, Acín-Pérez R, Martí-Mateos Y, Silla-Castro JC, Carro-Alvarellos M, Huertas JR, Vázquez J, Enríquez JA
Science advances 2020 Jun;6(26):eaba7509
Science advances 2020 Jun;6(26):eaba7509
Scaf1 promotes respiratory supercomplexes and metabolic efficiency in zebrafish.
García-Poyatos C, Cogliati S, Calvo E, Hernansanz-Agustín P, Lagarrigue S, Magni R, Botos M, Langa X, Amati F, Vázquez J, Mercader N, Enríquez JA
EMBO reports 2020 Jul 3;21(7):e50287
EMBO reports 2020 Jul 3;21(7):e50287
NCLX prevents cell death during adrenergic activation of the brown adipose tissue.
Assali EA, Jones AE, Veliova M, Acín-Pérez R, Taha M, Miller N, Shum M, Oliveira MF, Las G, Liesa M, Sekler I, Shirihai OS
Nature communications 2020 Jul 3;11(1):3347
Nature communications 2020 Jul 3;11(1):3347
A novel approach to measure mitochondrial respiration in frozen biological samples.
Acin-Perez R, Benador IY, Petcherski A, Veliova M, Benavides GA, Lagarrigue S, Caudal A, Vergnes L, Murphy AN, Karamanlidis G, Tian R, Reue K, Wanagat J, Sacks H, Amati F, Darley-Usmar VM, Liesa M, Divakaruni AS, Stiles L, Shirihai OS
The EMBO journal 2020 Jul 1;39(13):e104073
The EMBO journal 2020 Jul 1;39(13):e104073
Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function.
Wang J, Li S, Wang J, Wu F, Chen Y, Zhang H, Guo Y, Lin Y, Li L, Yu X, Liu T, Zhao Y
Aging 2020 Jan 6;12(1):650-671
Aging 2020 Jan 6;12(1):650-671
Romo1 is involved in the immune response of glioblastoma by regulating the function of macrophages.
Sun G, Cao Y, Qian C, Wan Z, Zhu J, Guo J, Shi L
Aging 2020 Jan 16;12(2):1114-1127
Aging 2020 Jan 16;12(2):1114-1127
Mitochondria in Embryogenesis: An Organellogenesis Perspective.
Arribat Y, Grepper D, Lagarrigue S, Richard J, Gachet M, Gut P, Amati F
Frontiers in cell and developmental biology 2019;7:282
Frontiers in cell and developmental biology 2019;7:282
Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.
Han Y, Wu P, Wang Z, Zhang Z, Sun S, Liu J, Gong S, Gao P, Iwakuma T, Molina-Vila MA, Chen BP, Zhang Y, Ji T, Mo Q, Chen P, Hu J, Wang S, Zhou J, Lu H, Gao Q
EBioMedicine 2019 Feb;40:92-105
EBioMedicine 2019 Feb;40:92-105
Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy.
Latorre-Pellicer A, Lechuga-Vieco AV, Johnston IG, Hämäläinen RH, Pellico J, Justo-Méndez R, Fernández-Toro JM, Clavería C, Guaras A, Sierra R, Llop J, Torres M, Criado LM, Suomalainen A, Jones NS, Ruíz-Cabello J, Enríquez JA
Cell metabolism 2019 Dec 3;30(6):1120-1130.e5
Cell metabolism 2019 Dec 3;30(6):1120-1130.e5
A Novel Tumor-Suppressor, CDH18, Inhibits Glioma Cell Invasiveness Via UQCRC2 and Correlates with the Prognosis of Glioma Patients.
Bai YH, Zhan YB, Yu B, Wang WW, Wang L, Zhou JQ, Chen RK, Zhang FJ, Zhao XW, Duan WC, Wang YM, Liu J, Bao JJ, Zhang ZY, Liu XZ
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(4):1755-1770
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(4):1755-1770
Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity.
Fu T, Xu Z, Liu L, Guo Q, Wu H, Liang X, Zhou D, Xiao L, Liu L, Liu Y, Zhu MS, Chen Q, Gan Z
Cell reports 2018 May 1;23(5):1357-1372
Cell reports 2018 May 1;23(5):1357-1372
Glutathione Reduction of Patulin-Evoked Cytotoxicity in HEK293 Cells by the Prevention of Oxidative Damage and the Mitochondrial Apoptotic Pathway.
Wang X, Jin C, Zhong Y, Li X, Han J, Xue W, Wu P, Xia X, Peng X
Journal of agricultural and food chemistry 2018 Jul 25;66(29):7775-7785
Journal of agricultural and food chemistry 2018 Jul 25;66(29):7775-7785
CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.
Han Y, Sun S, Zhao M, Zhang Z, Gong S, Gao P, Liu J, Zhou J, Ma D, Gao Q, Wu P
Disease markers 2016;2016:3528064
Disease markers 2016;2016:3528064
Mitochondrial Sirtuin Network Reveals Dynamic SIRT3-Dependent Deacetylation in Response to Membrane Depolarization.
Yang W, Nagasawa K, Münch C, Xu Y, Satterstrom K, Jeong S, Hayes SD, Jedrychowski MP, Vyas FS, Zaganjor E, Guarani V, Ringel AE, Gygi SP, Harper JW, Haigis MC
Cell 2016 Nov 3;167(4):985-1000.e21
Cell 2016 Nov 3;167(4):985-1000.e21
Mechanism of super-assembly of respiratory complexes III and IV.
Cogliati S, Calvo E, Loureiro M, Guaras AM, Nieto-Arellano R, Garcia-Poyatos C, Ezkurdia I, Mercader N, Vázquez J, Enriquez JA
Nature 2016 Nov 24;539(7630):579-582
Nature 2016 Nov 24;539(7630):579-582
COA7 (C1orf163/RESA1) mutations associated with mitochondrial leukoencephalopathy and cytochrome c oxidase deficiency.
Martinez Lyons A, Ardissone A, Reyes A, Robinson AJ, Moroni I, Ghezzi D, Fernandez-Vizarra E, Zeviani M
Journal of medical genetics 2016 Dec;53(12):846-849
Journal of medical genetics 2016 Dec;53(12):846-849
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 14742-1-AP(UQCRC2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using UQCRC2 antibody 14742-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 14742-1-AP(UQCRC2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 14742-1-AP(UQCRC2 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
