Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN393521 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-E2F Transcription Factor 6 (E2F6) (AA 1-282) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-282
- Isotype
- IgG
- Antibody clone number
- 1F7-A9
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis.
E2F6 inhibits cobalt chloride-mimetic hypoxia-induced apoptosis through E2F1.
E2F-6 suppresses growth-associated apoptosis of human hematopoietic progenitor cells by counteracting proapoptotic activity of E2F-1.
A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members.
The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation.
Cunningham JM, Vierkant RA, Sellers TA, Phelan C, Rider DN, Liebow M, Schildkraut J, Berchuck A, Couch FJ, Wang X, Fridley BL, Ovarian Cancer Association Consortium., Gentry-Maharaj A, Menon U, Hogdall E, Kjaer S, Whittemore A, DiCioccio R, Song H, Gayther SA, Ramus SJ, Pharaoh PD, Goode EL
British journal of cancer 2009 Oct 20;101(8):1461-8
British journal of cancer 2009 Oct 20;101(8):1461-8
E2F6 inhibits cobalt chloride-mimetic hypoxia-induced apoptosis through E2F1.
Yang WW, Shu B, Zhu Y, Yang HT
Molecular biology of the cell 2008 Sep;19(9):3691-700
Molecular biology of the cell 2008 Sep;19(9):3691-700
E2F-6 suppresses growth-associated apoptosis of human hematopoietic progenitor cells by counteracting proapoptotic activity of E2F-1.
Kikuchi J, Shimizu R, Wada T, Ando H, Nakamura M, Ozawa K, Furukawa Y
Stem cells (Dayton, Ohio) 2007 Oct;25(10):2439-47
Stem cells (Dayton, Ohio) 2007 Oct;25(10):2439-47
A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members.
Xu X, Bieda M, Jin VX, Rabinovich A, Oberley MJ, Green R, Farnham PJ
Genome research 2007 Nov;17(11):1550-61
Genome research 2007 Nov;17(11):1550-61
The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation.
Tahiliani M, Mei P, Fang R, Leonor T, Rutenberg M, Shimizu F, Li J, Rao A, Shi Y
Nature 2007 May 31;447(7144):601-5
Nature 2007 May 31;447(7144):601-5
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Supportive validation
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- IHC