Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 17869-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17869-1-AP, RRID:AB_10597697
- Product name
- MGAT3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MGAT3 antibody (Cat. #17869-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Bisecting GlcNAc enhances CD8(+) T cell-mediated killing of breast cancer by suppressing PD-L1 expression and its binding to PD-1.
FOXA2 Loss in TGF-β1-Induced EMT Suppresses Bisecting-GlcNAc N-Glycan Synthesis in Lung Adenocarcinoma.
Bisecting GlcNAc modification reverses the chemoresistance via attenuating the function of P-gp.
DHEC mesylate attenuates pathologies and aberrant bisecting N-glycosylation in Alzheimer's disease models.
LacdiNAc synthase B4GALNT3 has a unique PA14 domain and suppresses N-glycan capping.
Targeting aberrant glycosylation to modulate microglial response and improve cognition in models of Alzheimer's disease.
MGAT3-mediated glycosylation of tetraspanin CD82 at asparagine 157 suppresses ovarian cancer metastasis by inhibiting the integrin signaling pathway.
Ren X, Wu J, Li J, Zhai Z, Li X, Guan F, Wang M, Ma X, Tan Z, Kang H, Lin S
Experimental hematology & oncology 2025 Aug 4;14(1):102
Experimental hematology & oncology 2025 Aug 4;14(1):102
FOXA2 Loss in TGF-β1-Induced EMT Suppresses Bisecting-GlcNAc N-Glycan Synthesis in Lung Adenocarcinoma.
Ge W, Wen S, Zhou X, Chen Y, Zeng D, Jiang J, Yang S
Proteomics 2025 Apr;25(8):e202400216
Proteomics 2025 Apr;25(8):e202400216
Bisecting GlcNAc modification reverses the chemoresistance via attenuating the function of P-gp.
Tan Z, Ning L, Cao L, Zhou Y, Li J, Yang Y, Lin S, Ren X, Xue X, Kang H, Li X, Guan F
Theranostics 2024;14(13):5184-5199
Theranostics 2024;14(13):5184-5199
DHEC mesylate attenuates pathologies and aberrant bisecting N-glycosylation in Alzheimer's disease models.
Wang Y, Cao Y, Huang H, Xue Y, Chen S, Gao X
Neuropharmacology 2024 May 1;248:109863
Neuropharmacology 2024 May 1;248:109863
LacdiNAc synthase B4GALNT3 has a unique PA14 domain and suppresses N-glycan capping.
Tokoro Y, Nagae M, Nakano M, Harduin-Lepers A, Kizuka Y
The Journal of biological chemistry 2024 Jul;300(7):107450
The Journal of biological chemistry 2024 Jul;300(7):107450
Targeting aberrant glycosylation to modulate microglial response and improve cognition in models of Alzheimer's disease.
Wang Y, Du Y, Huang H, Cao Y, Pan K, Zhou Y, He J, Yao W, Chen S, Gao X
Pharmacological research 2024 Apr;202:107133
Pharmacological research 2024 Apr;202:107133
MGAT3-mediated glycosylation of tetraspanin CD82 at asparagine 157 suppresses ovarian cancer metastasis by inhibiting the integrin signaling pathway.
Li J, Xu J, Li L, Ianni A, Kumari P, Liu S, Sun P, Braun T, Tan X, Xiang R, Yue S
Theranostics 2020;10(14):6467-6482
Theranostics 2020;10(14):6467-6482
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- COLO 320 cells were subjected to SDS PAGE followed by western blot with 17869-1-AP(MGAT3 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 17869-1-AP(MGAT3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The MGAT3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MGAT3. This antibody recognizes human, mouse, rat antigen. The MGAT3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.