Antibody data
- Antibody Data
- Antigen structure
- References [0]
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- Validations
- Western blot [1]
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- Product number
- BS8286 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- GLP2R polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human GLP2R.
- Description
- Glucagon, a pancreatic hormone, functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior. Both Glucagon and GLP-1 function through their specific binding to the Glucagon Receptor or GLP-1R, respectively. The Glucagon Receptor is expressed in liver, kidney and adipose tissue. The GLP-1R expression primarily localizes to areas of the hypothalamus involved in feeding behavior. Both receptors and their ligands serve as potential targets for the therapeutic treatment of diabetes. Glucagon-like peptide 2 receptor, also designated GLP-2 receptor or glp-2r, acts as a receptor for Glucagon-like peptide 2 (GLP-2). GLP-2 is a nutrient-responsive hormone that has various functions in the gastrointestinal tract. The activity of GLP-2R, which is a multi-pass membrane protein, is mediated by G-proteins which activate adenylyl cyclase.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- WesternBlot (WB) analysis of GLP2R polyclonal antibody