Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN2845506 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) (AA 171-198), (Center) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 171-198, Center
- Antibody clone number
- RB32222
- Vial size
- 80 μL
- Storage
- ATF4 Antibody (Center) can be refrigerated at 2-8°C for up to 6 months. For long term storage, place the at -20°C.
Submitted references Control of activating transcription factor 4 (ATF4) persistence by multisite phosphorylation impacts cell cycle progression and neurogenesis.
Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response.
How do tumours adapt to nutrient stress?
The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells.
Regulation of autophagy by ATF4 in response to severe hypoxia.
Frank CL, Ge X, Xie Z, Zhou Y, Tsai LH
The Journal of biological chemistry 2010 Oct 22;285(43):33324-37
The Journal of biological chemistry 2010 Oct 22;285(43):33324-37
Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response.
Dey S, Baird TD, Zhou D, Palam LR, Spandau DF, Wek RC
The Journal of biological chemistry 2010 Oct 22;285(43):33165-74
The Journal of biological chemistry 2010 Oct 22;285(43):33165-74
How do tumours adapt to nutrient stress?
Wek RC, Staschke KA
The EMBO journal 2010 Jun 16;29(12):1946-7
The EMBO journal 2010 Jun 16;29(12):1946-7
The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells.
Liew CW, Bochenski J, Kawamori D, Hu J, Leech CA, Wanic K, Malecki M, Warram JH, Qi L, Krolewski AS, Kulkarni RN
The Journal of clinical investigation 2010 Aug;120(8):2876-88
The Journal of clinical investigation 2010 Aug;120(8):2876-88
Regulation of autophagy by ATF4 in response to severe hypoxia.
Rzymski T, Milani M, Pike L, Buffa F, Mellor HR, Winchester L, Pires I, Hammond E, Ragoussis I, Harris AL
Oncogene 2010 Aug 5;29(31):4424-35
Oncogene 2010 Aug 5;29(31):4424-35
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