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- References [17]
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- Product number
- 15366-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15366-1-AP, RRID:AB_2253650
- Product name
- RIPK2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RIPK2 antibody (Cat. #15366-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Transdermal Delivery of Icariin via Microneedle Patches Attenuates Phthalate-Induced Testicular Injury.
The Mechanism of Xuanyu Tongjing Decoction Regulating NOD/NFκB Pathway to Inhibit Ectopic Tissue Inflammation to Reduce Ovarian Damage in Rats with Ovarian Endometriosis.
H3K18 lactylation-mediated nucleotide-binding oligomerization domain-2 (NOD2) expression promotes bilirubin-induced pyroptosis of astrocytes.
β-Glucan modulates trained immunity to inhibit osteoclast differentiation via NOD2/RIPK2 signaling pathway.
Juanbi Qianggu Formula inhibits fibroblast-like synovicytes activation via repressing LncRNA ITSN1-2 to promote RIP2 K48 ubiquitination.
Identification of hub six interferon alpha response genes and immune cell infiltration characteristics in low-grade glioma.
N4BP3 facilitates NOD2-MAPK/NF-κB pathway in inflammatory bowel disease through mediating K63-linked RIPK2 ubiquitination.
Saikosaponin A protects against uremic toxin indole‑3 acetic acid‑induced damage to the myocardium.
OTUD1 ameliorates cerebral ischemic injury through inhibiting inflammation by disrupting K63-linked deubiquitination of RIP2.
DBDPE upregulates NOD-like receptor signaling to induce NLRP3 inflammasome-mediated HAECs pyroptosis.
M(6)A RNA Methylation Mediates NOD1/NF-kB Signaling Activation in the Liver of Piglets Challenged with Lipopolysaccharide.
Suppression of RIP1 activity via S415 dephosphorylation ameliorates obesity-related hepatic insulin resistance.
Chemotherapeutic Drugs Induce Different Gut Microbiota Disorder Pattern and NOD/RIP2/NF-κB Signaling Pathway Activation That Lead to Different Degrees of Intestinal Injury.
A small molecule inhibitor of caspase-1 inhibits NLRP3 inflammasome activation and pyroptosis to alleviate gouty inflammation.
Knockdown of RIPK2 Inhibits Proliferation and Migration, and Induces Apoptosis via the NF-κB Signaling Pathway in Gastric Cancer.
Extracellular Histone H3 Induces Pyroptosis During Sepsis and May Act Through NOD2 and VSIG4/NLRP3 Pathways.
Identification and Characterization of Novel Receptor-Interacting Serine/Threonine-Protein Kinase 2 Inhibitors Using Structural Similarity Analysis.
Fang C, Li Y, You R, Wong KH, Cai T, Gan RY, Ye Y
Advanced healthcare materials 2026 Mar;15(9):e03925
Advanced healthcare materials 2026 Mar;15(9):e03925
The Mechanism of Xuanyu Tongjing Decoction Regulating NOD/NFκB Pathway to Inhibit Ectopic Tissue Inflammation to Reduce Ovarian Damage in Rats with Ovarian Endometriosis.
Fan W, Zhai F, Yuan Z, Hu G, Wang L
Drug design, development and therapy 2025;19:2717-2735
Drug design, development and therapy 2025;19:2717-2735
H3K18 lactylation-mediated nucleotide-binding oligomerization domain-2 (NOD2) expression promotes bilirubin-induced pyroptosis of astrocytes.
Li J, Li S, Sun Q, Li L, Zhang Y, Hua Z
Journal of neuroinflammation 2025 Mar 12;22(1):76
Journal of neuroinflammation 2025 Mar 12;22(1):76
β-Glucan modulates trained immunity to inhibit osteoclast differentiation via NOD2/RIPK2 signaling pathway.
Li Y, Chen M, Yang Z, Li J, Ma L, Bao G, Chen Y, Hu J
International immunopharmacology 2025 Jun 26;159:114886
International immunopharmacology 2025 Jun 26;159:114886
Juanbi Qianggu Formula inhibits fibroblast-like synovicytes activation via repressing LncRNA ITSN1-2 to promote RIP2 K48 ubiquitination.
Bian Y, Li F, A X, Xiang Z, Ma N, Wang J, Cao B, Xin P, Cheng X, Liu C, Xiang B, Shen J, Lu Q, Xiao L
Chinese medicine 2025 Jul 8;20(1):109
Chinese medicine 2025 Jul 8;20(1):109
Identification of hub six interferon alpha response genes and immune cell infiltration characteristics in low-grade glioma.
Zhang X, Song S, Zhou D, Cui H, Xie J
Scientific reports 2025 Jul 12;15(1):25210
Scientific reports 2025 Jul 12;15(1):25210
N4BP3 facilitates NOD2-MAPK/NF-κB pathway in inflammatory bowel disease through mediating K63-linked RIPK2 ubiquitination.
Jiang W, Zhao Y, Han M, Xu J, Chen K, Liang Y, Yin J, Hu J, Shen Y
Cell death discovery 2024 Oct 17;10(1):440
Cell death discovery 2024 Oct 17;10(1):440
Saikosaponin A protects against uremic toxin indole‑3 acetic acid‑induced damage to the myocardium.
Chen C, Hu X, Chen X
Molecular medicine reports 2023 Sep;28(3)
Molecular medicine reports 2023 Sep;28(3)
OTUD1 ameliorates cerebral ischemic injury through inhibiting inflammation by disrupting K63-linked deubiquitination of RIP2.
Zheng S, Li Y, Song X, Wu M, Yu L, Huang G, Liu T, Zhang L, Shang M, Zhu Q, Gao C, Chen L, Liu H
Journal of neuroinflammation 2023 Nov 27;20(1):281
Journal of neuroinflammation 2023 Nov 27;20(1):281
DBDPE upregulates NOD-like receptor signaling to induce NLRP3 inflammasome-mediated HAECs pyroptosis.
Jing L, Zheng D, Sun X, Shi Z
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120882
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120882
M(6)A RNA Methylation Mediates NOD1/NF-kB Signaling Activation in the Liver of Piglets Challenged with Lipopolysaccharide.
Xu M, Zhuo R, Tao S, Liang Y, Liu C, Liu Q, Wang T, Zhong X
Antioxidants (Basel, Switzerland) 2022 Sep 30;11(10)
Antioxidants (Basel, Switzerland) 2022 Sep 30;11(10)
Suppression of RIP1 activity via S415 dephosphorylation ameliorates obesity-related hepatic insulin resistance.
Wang Y, Xiong J, Yuan Y, Peng C, Wu P, Wang Y, Lu J, Yin Y, Xu J, Chen S, Liu J
Obesity (Silver Spring, Md.) 2022 Mar;30(3):680-693
Obesity (Silver Spring, Md.) 2022 Mar;30(3):680-693
Chemotherapeutic Drugs Induce Different Gut Microbiota Disorder Pattern and NOD/RIP2/NF-κB Signaling Pathway Activation That Lead to Different Degrees of Intestinal Injury.
Huang B, Gui M, Ni Z, He Y, Zhao J, Peng J, Lin J
Microbiology spectrum 2022 Dec 21;10(6):e0167722
Microbiology spectrum 2022 Dec 21;10(6):e0167722
A small molecule inhibitor of caspase-1 inhibits NLRP3 inflammasome activation and pyroptosis to alleviate gouty inflammation.
Cao DY, Zhang ZH, Li RZ, Shi XK, Xi RY, Zhang GL, Li F, Wang F
Immunology letters 2022 Apr;244:28-39
Immunology letters 2022 Apr;244:28-39
Knockdown of RIPK2 Inhibits Proliferation and Migration, and Induces Apoptosis via the NF-κB Signaling Pathway in Gastric Cancer.
Yang Q, Tian S, Liu Z, Dong W
Frontiers in genetics 2021;12:627464
Frontiers in genetics 2021;12:627464
Extracellular Histone H3 Induces Pyroptosis During Sepsis and May Act Through NOD2 and VSIG4/NLRP3 Pathways.
Shi CX, Wang Y, Chen Q, Jiao FZ, Pei MH, Gong ZJ
Frontiers in cellular and infection microbiology 2020;10:196
Frontiers in cellular and infection microbiology 2020;10:196
Identification and Characterization of Novel Receptor-Interacting Serine/Threonine-Protein Kinase 2 Inhibitors Using Structural Similarity Analysis.
Salla M, Aguayo-Ortiz R, Danmaliki GI, Zare A, Said A, Moore J, Pandya V, Manaloor R, Fong S, Blankstein AR, Gibson SB, Garcia LR, Meier P, Bhullar KS, Hubbard BP, Fiteh Y, Vliagoftis H, Goping IS, Brocks D, Hwang P, Velázquez-Martínez CA, Baksh S
The Journal of pharmacology and experimental therapeutics 2018 May;365(2):354-367
The Journal of pharmacology and experimental therapeutics 2018 May;365(2):354-367
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RIPK2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RIPK2. This antibody recognizes human,mouse,rat antigen. The RIPK2 antibody has been validated for the following applications: ELISA, WB analysis.
