20150-1-AP

antibody from Proteintech Group

Targeting: LGR4 GPR48

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

20150-1-AP

Provider

Proteintech Group

Product name

LGR4 antibody

Antibody type

Polyclonal

Description

LGR4 antibody (Cat. #20150-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Construction and clinical validation of a machine-learning-based consensus prognostic signature (MLPS) for osteosarcoma via multi-cohort data integration.

Chen L, Wu H, Ren R, Zhang Y, Zhu Z, Chen X, Wang L, Gan X, Kang H, Pu H, Xiong W
International immunopharmacology 2026 Jan 1;168(Pt 1):115831

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Electromagnetic field-inducible in vivo gene switch for remote spatiotemporal control of gene expression.

Kim J, Hwang Y, Kim S, Kwon D, Park J, Cho B, An S, Kang S, Kim Y, Kim S, Lengner CJ, Kim S, Kwon Y, Sung JS, Kim J
Cell 2026 Apr 14;

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Deficiency of Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 in Pancreas Reduces β Cell Mass.

Luo C, Feng Y, Min J, Zhao Y, Zhu Z, Sun L, Yin H, Yin Y, Zhang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e08858

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Leucine-rich repeat-containing G protein-coupled receptor 4 promotes proliferation, invasion and migration, and inhibits apoptosis in non-small cell lung cancer cells.

Duan X, Liu X, Shan Y, Zhou S, Lou M, Gao Z, Yuan K
Oncology letters 2025 Dec;30(6):558

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Multi-omics analysis reveals that ALYREF-mediated m(5)C modification promotes platinum resistance in ovarian cancer via the NSUN2/ALYREF/LGR4 axis.

Yang S, He P, Wang W, Xu X, Xi X, Li Y
Cell death & disease 2025 Dec 5;17(1):77

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LGR4 attenuates MGP expression and suppresses EGFR activation-induced triple-negative breast cancer metastasis.

Li Q, Gao Y, Huo Z, Liu J, Zhang P, Wang Y
American journal of cancer research 2024;14(7):3419-3432

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SOX2 suppresses osteoblast differentiation of MC3T3-E1 cells through activating the transcription of LGR4.

Chen S, Xiao Z, Jiang W
In vitro cellular & developmental biology. Animal 2023 Jan;59(1):1-9

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DNA methylation mediated RSPO2 to promote follicular development in mammals.

Zhou X, He Y, Li N, Bai G, Pan X, Zhang Z, Zhang H, Li J, Yuan X
Cell death & disease 2021 Jun 26;12(7):653

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Silencing of RSPO1 mitigates obesity-related renal fibrosis in mice by deactivating Wnt/β-catenin pathway.

Su X, Zhou G, Tian M, Wu S, Wang Y
Experimental cell research 2021 Aug 15;405(2):112713

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LGR4 overexpression is associated with clinical parameters and poor prognosis of serous ovarian cancer.

Zeng Z, Ji N, Yi J, Lv J, Yuan J, Lin Z, Liu L, Feng X
Cancer biomarkers : section A of Disease markers 2020;28(1):65-72

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Silencing LGR6 Attenuates Stemness and Chemoresistance via Inhibiting Wnt/β-Catenin Signaling in Ovarian Cancer.

Ruan X, Liu A, Zhong M, Wei J, Zhang W, Rong Y, Liu W, Li M, Qing X, Chen G, Li R, Liao Y, Liu Q, Zhang X, Ren D, Wang Y
Molecular therapy oncolytics 2019 Sep 27;14:94-106

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LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis.

Zhu P, Wu J, Wang Y, Zhu X, Lu T, Liu B, He L, Ye B, Wang S, Meng S, Fan D, Wang J, Yang L, Qin X, Du Y, Li C, He L, Ren W, Wu X, Tian Y, Fan Z
Nature cell biology 2018 Oct;20(10):1134-1144