Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- MAB2145-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse CXCR6 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Stains mouse CXCR6-transfected cells but not irrelevant transfectants.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Antigen sequence
Q9EQ16
- Isotype
- IgG
- Antibody clone number
- 221002
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Hepatectomy leads to loss of TRAIL-expressing liver NK cells via downregulation of the CXCL9-CXCR3 axis in mice.
The chemokine receptor CXCR6 contributes to recruitment of bone marrow-derived fibroblast precursors in renal fibrosis.
The chemokine CXCL16 induces migration and invasion of glial precursor cells via its receptor CXCR6.
Yano T, Ohira M, Nakano R, Tanaka Y, Ohdan H
PloS one 2017;12(10):e0186997
PloS one 2017;12(10):e0186997
The chemokine receptor CXCR6 contributes to recruitment of bone marrow-derived fibroblast precursors in renal fibrosis.
Xia Y, Yan J, Jin X, Entman ML, Wang Y
Kidney international 2014 Aug;86(2):327-37
Kidney international 2014 Aug;86(2):327-37
The chemokine CXCL16 induces migration and invasion of glial precursor cells via its receptor CXCR6.
Hattermann K, Ludwig A, Gieselmann V, Held-Feindt J, Mentlein R
Molecular and cellular neurosciences 2008 Sep;39(1):133-41
Molecular and cellular neurosciences 2008 Sep;39(1):133-41
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Supportive validation
- Submitted by
- R&D Systems (provider)
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- Experimental details
- Detection of CXCR6 in BaF3 Mouse Cell Line Transfected with Mouse CXCR6 and eGFP by Flow Cytometry. BaF3 mouse pro-B cell line transfected with mouse CXCR6 and eGFP was stained with and either (A) Rat Anti-Mouse CXCR6 Monoclonal Antibody (Catalog # MAB2145) or (B) Rat IgG2B Isotype Control (Catalog # MAB0061) followed by Allophycocyanin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0113). View our protocol for Staining Membrane-associated Proteins.