Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 11304-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11304-1-AP, RRID:AB_2173932
- Product name
- Rab18 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Rab18 antibody (Cat. #11304-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references RINT1 deficiency disrupts lipid metabolism and underlies a complex hereditary spastic paraplegia.
Perilipin-2 promotes lipid droplet-plasma membrane interactions that facilitate apocrine lipid secretion in secretory epithelial cells of the mouse mammary gland.
KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice.
Pu-erh tea increases the metabolite Cinnabarinic acid to improve circadian rhythm disorder-induced obesity.
Fatty Acid Synthase Is Involved in Classical Swine Fever Virus Replication by Interaction with NS4B.
Rab18 Regulates Proliferation, Invasion and Cisplatin Sensitivity Through STAT3 Signaling in Head and Neck Squamous Cell Carcinoma.
Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B.
Rab18 overexpression promotes proliferation and chemoresistance through regulation of mitochondrial function in human gastric cancer.
Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells.
The RAB GTPase RAB18 modulates macroautophagy and proteostasis.
ENU mutagenesis identifies mice modeling Warburg Micro Syndrome with sensory axon degeneration caused by a deletion in Rab18.
MicroRNA-30b/c inhibits non-small cell lung cancer cell proliferation by targeting Rab18.
Rab18 and a Rab18 GEF complex are required for normal ER structure.
Rab18 binds to hepatitis C virus NS5A and promotes interaction between sites of viral replication and lipid droplets.
Hepatitis B virus X protein upregulates oncogene Rab18 to result in the dysregulation of lipogenesis and proliferation of hepatoma cells.
Launay N, Ruiz M, Planas-Serra L, Verdura E, Rodríguez-Palmero A, Schlüter A, Goicoechea L, Guilera C, Casas J, Campelo F, Jouanguy E, Casanova JL, Boespflug-Tanguy O, Vazquez Cancela M, Gutiérrez-Solana LG, Casasnovas C, Area-Gomez E, Pujol A
The Journal of clinical investigation 2023 Jul 17;133(14)
The Journal of clinical investigation 2023 Jul 17;133(14)
Perilipin-2 promotes lipid droplet-plasma membrane interactions that facilitate apocrine lipid secretion in secretory epithelial cells of the mouse mammary gland.
Monks J, Orlicky DJ, Libby AE, Dzieciatkowska M, Ladinsky MS, McManaman JL
Frontiers in cell and developmental biology 2022;10:958566
Frontiers in cell and developmental biology 2022;10:958566
KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice.
Wang S, Tanaka Y, Xu Y, Takeda S, Hirokawa N
Developmental cell 2022 Oct 10;57(19):2273-2289.e11
Developmental cell 2022 Oct 10;57(19):2273-2289.e11
Pu-erh tea increases the metabolite Cinnabarinic acid to improve circadian rhythm disorder-induced obesity.
Hu S, Hu C, Luo L, Zhang H, Zhao S, Liu Z, Zeng L
Food chemistry 2022 Nov 15;394:133500
Food chemistry 2022 Nov 15;394:133500
Fatty Acid Synthase Is Involved in Classical Swine Fever Virus Replication by Interaction with NS4B.
Liu YY, Liang XD, Liu CC, Cheng Y, Chen H, Baloch AS, Zhang J, Go YY, Zhou B
Journal of virology 2021 Aug 10;95(17):e0078121
Journal of virology 2021 Aug 10;95(17):e0078121
Rab18 Regulates Proliferation, Invasion and Cisplatin Sensitivity Through STAT3 Signaling in Head and Neck Squamous Cell Carcinoma.
Ji X, Guo X, Wang Y, Li X, Li H
OncoTargets and therapy 2020;13:4123-4134
OncoTargets and therapy 2020;13:4123-4134
Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B.
Nian FS, Li LL, Cheng CY, Wu PC, Lin YT, Tang CY, Ren BS, Tai CY, Fann MJ, Kao LS, Hong CJ, Tsai JW
Molecular neurobiology 2019 Sep;56(9):6095-6105
Molecular neurobiology 2019 Sep;56(9):6095-6105
Rab18 overexpression promotes proliferation and chemoresistance through regulation of mitochondrial function in human gastric cancer.
Wu B, Qi R, Liu X, Qian L, Wu Z
OncoTargets and therapy 2018;11:7805-7820
OncoTargets and therapy 2018;11:7805-7820
Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells.
Jayson CBK, Arlt H, Fischer AW, Lai ZW, Farese RV Jr, Walther TC
Molecular biology of the cell 2018 Aug 15;29(17):2045-2054
Molecular biology of the cell 2018 Aug 15;29(17):2045-2054
The RAB GTPase RAB18 modulates macroautophagy and proteostasis.
Feldmann A, Bekbulat F, Huesmann H, Ulbrich S, Tatzelt J, Behl C, Kern A
Biochemical and biophysical research communications 2017 May 6;486(3):738-743
Biochemical and biophysical research communications 2017 May 6;486(3):738-743
ENU mutagenesis identifies mice modeling Warburg Micro Syndrome with sensory axon degeneration caused by a deletion in Rab18.
Cheng CY, Wu JC, Tsai JW, Nian FS, Wu PC, Kao LS, Fann MJ, Tsai SJ, Liou YJ, Tai CY, Hong CJ
Experimental neurology 2015 May;267:143-51
Experimental neurology 2015 May;267:143-51
MicroRNA-30b/c inhibits non-small cell lung cancer cell proliferation by targeting Rab18.
Zhong K, Chen K, Han L, Li B
BMC cancer 2014 Sep 24;14:703
BMC cancer 2014 Sep 24;14:703
Rab18 and a Rab18 GEF complex are required for normal ER structure.
Gerondopoulos A, Bastos RN, Yoshimura S, Anderson R, Carpanini S, Aligianis I, Handley MT, Barr FA
The Journal of cell biology 2014 Jun 9;205(5):707-20
The Journal of cell biology 2014 Jun 9;205(5):707-20
Rab18 binds to hepatitis C virus NS5A and promotes interaction between sites of viral replication and lipid droplets.
Salloum S, Wang H, Ferguson C, Parton RG, Tai AW
PLoS pathogens 2013;9(8):e1003513
PLoS pathogens 2013;9(8):e1003513
Hepatitis B virus X protein upregulates oncogene Rab18 to result in the dysregulation of lipogenesis and proliferation of hepatoma cells.
You X, Liu F, Zhang T, Li Y, Ye L, Zhang X
Carcinogenesis 2013 Jul;34(7):1644-52
Carcinogenesis 2013 Jul;34(7):1644-52
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 11304-1-AP(RAB18 antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Rab18 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Rab18. This antibody recognizes human, mouse, rat antigen. The Rab18 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 11304-1-AP(RAB18 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue