11-8060

KDM8 antibody from ABEOMICS Inc.
FLJ13798, JMJD5

Antibody data

Product number
11-8060
Provider
ABEOMICS Inc.
Product name
Anti-JMJD5 Antibody
Provider product page
ABEOMICS Inc. - 11-8060
Antibody type
Polyclonal
Description
JMJD5 (Jumonji domain-containing protein 5) or commonly called as Lysine-specific demethylase 8 is a histone lysine demethylase that specifically demethylates dimethylated Lys 36 of histone H3 (H3K36me2) thereby activating the target gene. JMJD5 is important for G2/M phase cell cycle progression. JMJD5 is also a potential tumor suppression protein. JMJD5 helps in regulation of cancer proliferation by regulating cyclin-A1. JMJD5 has three isoforms (47, 24, 50 kDa), all localized in nucleus. JMJD5 is weakly expressed in most normal cells but highly expressed in breast cancer cells.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant JMJD5
protein (amino acids 20-220) was us
ed as the immunogen for this antibo
dy.
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
Provider Type Product Number
- No reagents -