BS8927

antibody from Bioworld Technology, Inc
Targeting: IL21R CD360
Provider product page for BS8927
Western blot
Immunohistochemistry

Antibody data

Product number
BS8927 - Provider product page
Provider
Bioworld Technology, Inc
Product name
IL21R polyclonal antibody
Antibody type
Polyclonal
Antigen
Interleukin-21 receptor; IL-21 receptor; IL-21R; Novel interleukin receptor; CD360; IL21R; NILR; UNQ3121/PRO10273
Description
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
IL21R protein structure - BS8927 shown in red.