66670-1-Ig

antibody from Proteintech Group

Targeting: IRF3

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66670-1-Ig

Provider

Proteintech Group

Product name

IRF3 antibody

Antibody type

Monoclonal

Description

IRF3 antibody (Cat. #66670-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1E6G8

Vial size

20ul, 150ul

References

Submitted references

Deubiquitinase USP4 suppresses antitumor immunity by inhibiting IRF3 activation and tumor cell-intrinsic interferon response in colorectal cancer.

Zhou Y, Li H, Zhang Y, Zhao E, Huang C, Pan X, Shu F, Liu Z, Tang N, Li F, Liao W
Cancer letters 2024 May 1;589:216836

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CKLF induces microglial activation via triggering defective mitophagy and mitochondrial dysfunction.

Wang H, Ye J, Peng Y, Ma W, Chen H, Sun H, Feng Z, He W, Li G, Chu S, Zhang Z, Chen N
Autophagy 2024 Mar;20(3):590-613

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IDI1 inhibits the cGAS-Sting signaling pathway in hepatocellular carcinoma.

Fu L, Ding H, Bai Y, Cheng L, Hu S, Guo Q
Heliyon 2024 Mar 15;10(5):e27205

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Mammalian orthoreovirus capsid protein σ3 antagonizes RLR-mediated antiviral responses by degrading MAVS.

Li D, Mo R, Li X, Cheng R, Xie J, Li H, Yang Y, Li S, Li H, Yan Z, Wei S, Idris A, Li X, Feng R
mSphere 2024 Jun 25;9(6):e0023624

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Anemoside B4 inhibits SARS-CoV-2 replication in vitro and in vivo.

Xiao M, Luo R, Liang Q, Jiang H, Liu Y, Xu G, Gao H, Zheng Y, Xu Q, Yang S
Chinese herbal medicines 2024 Jan;16(1):106-112

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SADS-CoV nsp1 inhibits the IFN-β production by preventing TBK1 phosphorylation and inducing CBP degradation.

Xiang Y, Mou C, Shi K, Chen X, Meng X, Bao W, Chen Z
Journal of medical virology 2023 Sep;95(9):e29104

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Bacterial vesicles block viral replication in macrophages via TLR4-TRIF-axis.

Bierwagen J, Wiegand M, Laakmann K, Danov O, Limburg H, Herbel SM, Heimerl T, Dorna J, Jonigk D, Preußer C, Bertrams W, Braun A, Sewald K, Schulte LN, Bauer S, Pogge von Strandmann E, Böttcher-Friebertshäuser E, Schmeck B, Jung AL
Cell communication and signaling : CCS 2023 Mar 28;21(1):65

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Nuclear translocation of cGAS orchestrates VEGF-A-mediated angiogenesis.

Luo J, Lu C, Chen Y, Wu X, Zhu C, Cui W, Yu S, Li N, Pan Y, Zhao W, Yang Q, Yang X
Cell reports 2023 Apr 25;42(4):112328

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DDX56 antagonizes IFN-β production to enhance EMCV replication by inhibiting IRF3 nuclear translocation.

Xu S, Xie J, Zhang X, Chen L, Bi Y, Li X, Idris A, Feng R
Veterinary microbiology 2022 Jan;264:109304

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MIR155HG Plays a Bivalent Role in Regulating Innate Antiviral Immunity by Encoding Long Noncoding RNA-155 and microRNA-155-5p.

Rai KR, Liao Y, Cai M, Qiu H, Wen F, Peng M, Wang S, Liu S, Guo G, Chi X, Maarouf M, Chen Y, Huang S, Chen JL
mBio 2022 Dec 20;13(6):e0251022

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Swine Acute Diarrhea Syndrome Coronavirus Nucleocapsid Protein Antagonizes Interferon-β Production via Blocking the Interaction Between TRAF3 and TBK1.

Zhou Z, Sun Y, Xu J, Tang X, Zhou L, Li Q, Lan T, Ma J
Frontiers in immunology 2021;12:573078