MA5-14947

antibody from Invitrogen Antibodies

Targeting: IRF3

Western blot (Recommended by provider)

Other assay (Supportive data in Antibodypedia)

Antibody Data

Product number

MA5-14947

Provider

Invitrogen Antibodies

Product name

Phospho-IRF3 (Ser396) Monoclonal Antibody (E.875.8)

Antibody type

Monoclonal

Antigen

Synthetic peptide

Description

It is not recommended to aliquot this antibody.

Reactivity

Human, Mouse

Host

Rabbit

Isotype

IgG

Antibody clone number

E.875.8

Vial size

100 µL

Concentration

46 µg/mL

Storage

-20°C

References

Submitted references

Mechanism of selenomethionine inhibiting of PDCoV replication in LLC-PK1 cells based on STAT3/miR-125b-5p-1/HK2 signaling.

Ren Z, Ding T, He H, Wei Z, Shi R, Deng J
Frontiers in immunology 2022;13:952852

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African Swine Fever Virus Structural Protein p17 Inhibits cGAS-STING Signaling Pathway Through Interacting With STING.

Zheng W, Xia N, Zhang J, Cao Q, Jiang S, Luo J, Wang H, Chen N, Zhang Q, Meurens F, Zhu J
Frontiers in immunology 2022;13:941579

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Antiviral Effect of Selenomethionine on Porcine Deltacoronavirus in Pig Kidney Epithelial Cells.

Ren Z, Jia G, He H, Ding T, Yu Y, Zuo Z, Hu Y, Zhong Z, Yu S, Deng H, Shen L, Cao S, Peng G, Wang Y, Cai D, Gou L, Ma X, Liu H, Zhou Z, Deng Y, Yang D, Deng J
Frontiers in microbiology 2022;13:846747

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An autoinhibitory mechanism modulates MAVS activity in antiviral innate immune response.

Shi Y, Yuan B, Qi N, Zhu W, Su J, Li X, Qi P, Zhang D, Hou F
Nature communications 2015 Jul 17;6:7811

Other assay

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

FIGURE 2 Effects of Set-Met on the expression of MAVS protein and the phosphorylation of IRF-3 induced by PDCoV. LLC-PK cells were incubated with PDCoV for 1 h, and 2, 4, 8, and 16 muM of Se-Met was added. The expression of MAVS protein and the phosphorylation of IRF-3 were detected by western blot. Results were mean +- SD for three individual experiments.