ABIN1002558

antibody from antibodies-online

Targeting: IRF3

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1002558

Provider

antibodies-online

Product name

anti-Interferon Regulatory Factor 3 (IRF3) (C-Term) antibody

Antibody type

Polyclonal

Antigen

Rabbit polyclol IRF3 antibody was raised against a peptide corresponding to 14 amino acids near the carboxy-terminus of human IRF3 (GenBank accession no. AAO24761). IRF3 antibody is human and mouse reactive.

Reactivity

Human, Mouse

Host

Rabbit

Isotype

IgG

Vial size

100 µg

Storage

-20°C Shipping Temperature: 4°C

Handling

Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.

References

Submitted references

Induction and regulation of IFNs during viral infections.

Malmgaard L
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2004 Aug;24(8):439-54

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM, Maniatis T
Nature immunology 2003 May;4(5):491-6

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Triggering the interferon antiviral response through an IKK-related pathway.

Sharma S, tenOever BR, Grandvaux N, Zhou GP, Lin R, Hiscott J
Science (New York, N.Y.) 2003 May 16;300(5622):1148-51

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Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes.

Au WC, Moore PA, Lowther W, Juang YT, Pitha PM
Proceedings of the National Academy of Sciences of the United States of America 1995 Dec 5;92(25):11657-61