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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations [0]
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- Product number
- HPA021662 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA021662, RRID:AB_1858760
- Product name
- Anti-VPS13A
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human VPS13A, Gene description: vacuolar protein sorting 13 homolog A (S. cerevisiae), Alternative Gene Names: CHAC, KIAA0986, Validated applications: IHC, Uniprot ID: Q96RL7, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Chorein deficiency promotes ferroptosis.
Preserved VPS13A distribution and expression in Huntington’s disease: divergent mechanisms of action for similar movement disorders?
Case report: Neuroacanthocytosis associated with novel variants in the VPS13A gene with concomitant nucleotide expansion for CANVAS and assessment with osmotic gradient ektacytometry
Novel Biallelic Synonymous Exonic Variant in VPS13A Affecting mRNA Splicing
The association of lipid transfer protein VPS13A with endosomes is mediated by sorting nexin SNX5
Effect of rapamycin on lysosomal accumulation in a CRISPR/Cas9‐based cellular model of VPS13A deficiency
Interaction between VPS13A and the XK scramblase is important for VPS13A function in humans
Unraveling the Spatiotemporal Distribution of VPS13A in the Mouse Brain
Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility
Novel pathogenic XK mutations in McLeod syndrome and interaction between XK protein and chorein.
VPS13A, a closely associated mitochondrial protein, is required for efficient lysosomal degradation
Drosophila Vps13 Is Required for Protein Homeostasis in the Brain
Nishizawa Y, Sakimoto H, Nagata O, Sasaki N, Urata Y, Arai K, Hiwatashi H, Yokoyama I, Kishida S, Sano A, Nakamura M
FEBS open bio 2025 Jan;15(1):58-68
FEBS open bio 2025 Jan;15(1):58-68
Preserved VPS13A distribution and expression in Huntington’s disease: divergent mechanisms of action for similar movement disorders?
García-García E, Carreras-Caballé M, Coll-Manzano A, Ramón-Lainez A, Besa-Selva G, Pérez-Navarro E, Malagelada C, Alberch J, Masana M, Rodríguez M
Frontiers in Neuroscience 2024;18
Frontiers in Neuroscience 2024;18
Case report: Neuroacanthocytosis associated with novel variants in the VPS13A gene with concomitant nucleotide expansion for CANVAS and assessment with osmotic gradient ektacytometry
Paucar M, Wincent J, Rubin C, Peikert K, Kyhle J, Hertegård S, Möller R, Beshara S, Svenningsson P
Frontiers in Neuroscience 2024;18
Frontiers in Neuroscience 2024;18
Novel Biallelic Synonymous Exonic Variant in VPS13A Affecting mRNA Splicing
Hoe R, Zhao Y, Ong H, Tay K, Tan N, Khor M, Fan B, Peikert K, Hermann A, Neo S, Chen Z
Neurology Genetics 2024;10(6)
Neurology Genetics 2024;10(6)
The association of lipid transfer protein VPS13A with endosomes is mediated by sorting nexin SNX5
Tornero-Écija A, Zapata-del-Baño A, Antón-Esteban L, Vincent O, Escalante R
Life Science Alliance 2023;6(6):e202201852
Life Science Alliance 2023;6(6):e202201852
Effect of rapamycin on lysosomal accumulation in a CRISPR/Cas9‐based cellular model of VPS13A deficiency
Tornero‐Écija A, Navas M, Muñoz‐Braceras S, Vincent O, Escalante R
Journal of Cellular and Molecular Medicine 2023;27(11):1557-1564
Journal of Cellular and Molecular Medicine 2023;27(11):1557-1564
Interaction between VPS13A and the XK scramblase is important for VPS13A function in humans
Park J, Hu Y, Hollingsworth N, Miltenberger-Miltenyi G, Neiman A
Journal of Cell Science 2022;135(17)
Journal of Cell Science 2022;135(17)
Unraveling the Spatiotemporal Distribution of VPS13A in the Mouse Brain
García-García E, Chaparro-Cabanillas N, Coll-Manzano A, Carreras-Caballé M, Giralt A, Del Toro D, Alberch J, Masana M, Rodríguez M
International Journal of Molecular Sciences 2021;22(23):13018
International Journal of Molecular Sciences 2021;22(23):13018
Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility
Yeshaw W, van der Zwaag M, Pinto F, Lahaye L, Faber A, Gómez-Sánchez R, Dolga A, Poland C, Monaco A, van IJzendoorn S, Grzeschik N, Velayos-Baeza A, Sibon O
eLife 2019;8
eLife 2019;8
Novel pathogenic XK mutations in McLeod syndrome and interaction between XK protein and chorein.
Urata Y, Nakamura M, Sasaki N, Shiokawa N, Nishida Y, Arai K, Hiwatashi H, Yokoyama I, Narumi S, Terayama Y, Murakami T, Ugawa Y, Sakamoto H, Kaneko S, Nakazawa Y, Yamasaki R, Sadashima S, Sakai T, Arai H, Sano A
Neurology. Genetics 2019 Jun;5(3):e328
Neurology. Genetics 2019 Jun;5(3):e328
VPS13A, a closely associated mitochondrial protein, is required for efficient lysosomal degradation
Muñoz-Braceras S, Tornero-Écija A, Vincent O, Escalante R
Disease Models & Mechanisms 2019
Disease Models & Mechanisms 2019
Drosophila Vps13 Is Required for Protein Homeostasis in the Brain
Missirlis F, Vonk J, Yeshaw W, Pinto F, Faber A, Lahaye L, Kanon B, van der Zwaag M, Velayos-Baeza A, Freire R, van IJzendoorn S, Grzeschik N, Sibon O
PLOS ONE 2017;12(1):e0170106
PLOS ONE 2017;12(1):e0170106
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