Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Immunohistochemistry [4]
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- Product number
- NBP1-85641 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-85641, RRID:AB_11008734
- Product name
- Rabbit Polyclonal Chorein Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human Chorein antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Chorea-acanthocytosis with a novel mutation in the vacuolar protein sorting 13 homolog a gene: A case report.
Novel pathogenic VPS13A gene mutations in Japanese patients with chorea-acanthocytosis.
Mouse model of chorea-acanthocytosis exhibits male infertility caused by impaired sperm motility as a result of ultrastructural morphological abnormalities in the mitochondrial sheath in the sperm midpiece.
VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites.
Chorein interacts with α-tubulin and histone deacetylase 6, and overexpression preserves cell viability during nutrient deprivation in human embryonic kidney 293 cells.
Tada Y, Hamaguchi T, Ikeda Y, Iwasa K, Nishida Y, Nakamura M, Sano A, Yamada M
Journal of the neurological sciences 2020 May 15;412:116731
Journal of the neurological sciences 2020 May 15;412:116731
Novel pathogenic VPS13A gene mutations in Japanese patients with chorea-acanthocytosis.
Nishida Y, Nakamura M, Urata Y, Kasamo K, Hiwatashi H, Yokoyama I, Mizobuchi M, Sakurai K, Osaki Y, Morita Y, Watanabe M, Yoshida K, Yamane K, Miyakoshi N, Okiyama R, Ueda T, Wakasugi N, Saitoh Y, Sakamoto T, Takahashi Y, Shibano K, Tokuoka H, Hara A, Monma K, Ogata K, Kakuda K, Mochizuki H, Arai T, Araki M, Fujii T, Tsukita K, Sakamaki-Tsukita H, Sano A
Neurology. Genetics 2019 Jun;5(3):e332
Neurology. Genetics 2019 Jun;5(3):e332
Mouse model of chorea-acanthocytosis exhibits male infertility caused by impaired sperm motility as a result of ultrastructural morphological abnormalities in the mitochondrial sheath in the sperm midpiece.
Nagata O, Nakamura M, Sakimoto H, Urata Y, Sasaki N, Shiokawa N, Sano A
Biochemical and biophysical research communications 2018 Sep 5;503(2):915-920
Biochemical and biophysical research communications 2018 Sep 5;503(2):915-920
VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites.
Kumar N, Leonzino M, Hancock-Cerutti W, Horenkamp FA, Li P, Lees JA, Wheeler H, Reinisch KM, De Camilli P
The Journal of cell biology 2018 Oct 1;217(10):3625-3639
The Journal of cell biology 2018 Oct 1;217(10):3625-3639
Chorein interacts with α-tubulin and histone deacetylase 6, and overexpression preserves cell viability during nutrient deprivation in human embryonic kidney 293 cells.
Sasaki N, Nakamura M, Kodama A, Urata Y, Shiokawa N, Hayashi T, Sano A
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2016 Nov;30(11):3726-3732
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2016 Nov;30(11):3726-3732
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Chorein Antibody [NBP1-85641] - Staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Chorein Antibody [NBP1-85641] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Chorein Antibody [NBP1-85641] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Chorein Antibody [NBP1-85641] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.