Tissue expression
Cell line expression
Protein structure
MYCN
MYCN proto-oncogene, bHLH transcription factorbHLHe37, MYCNOT, N-myc, NMYC
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Top validated antibodies |
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Novus Biologicals | ![]() |
5 references | Monoclonal |
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GeneTex | ![]() |
Monoclonal |
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Proteintech Group | ![]() |
18 references | Polyclonal |
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antibodies-online | ![]() |
3 references | Monoclonal |
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LSBio | ![]() |
Polyclonal |
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