Ab114573

antibody from Aladdin Scientific Corporation

Targeting: MCM7 CDC47, MCM2, PPP1R104

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

Ab114573

Provider

Aladdin Scientific Corporation

Product name

Recombinant MCM7/PRL Antibody

Antibody type

Recombinant

Description

Rabbit anti Human MCM7/PRL Antibody, Recombinant (R02-7D2), could be used for WB, IHC and so on.Application:WB: 1/500-1/1000 IHC: 1/50-1/100Protein FunctionActs as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AA 671-683


Antibody clone number

R02-7D2

Vial size

100μl,10μl,1ml,50μl

Concentration

0,3 mg/ml

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.