Ab114573

antibody from Aladdin Scientific

Targeting: MCM7 CDC47, MCM2, PPP1R104

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Product number: Ab114573 - Provider product page
Provider: Aladdin Scientific
Product name: Recombinant MCM7/PRL Antibody
Antibody type: Recombinant
Description: Rabbit anti Human MCM7/PRL Antibody, Recombinant, could be used for WB, IHC and so on.Application:WB: 1/500-1/1000 IHC: 1/50-1/100Protein FunctionActs as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: AA 671-683
Vial size: 100_l,10_l,1ml,50_l
Concentration: 0,3 mg/ml
Storage: Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

MCM7 protein structure - Ab114573 shown in red.