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- References [21]
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- Western blot [1]
- Immunoprecipitation [1]
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- Product number
- 18099-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18099-1-AP, RRID:AB_10837364
- Product name
- TRAF3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TRAF3 antibody (Cat. #18099-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TRAIP suppressed apoptosis and cell cycle to promote prostate cancer proliferation via TRAF2-PI3K-AKT pathway activation.
Estrogen receptor alpha signaling in dendritic cells modulates autoimmune disease phenotype in mice.
TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion.
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
TDRD3 is an antiviral restriction factor that promotes IFN signaling with G3BP1.
The N6-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response.
Evolutionary history and functional characterization of Lj-TICAM-a and Lj-TICAM-b formed via lineage-specific tandem duplication in lamprey (Lampetra japonica).
TNF receptor-associated factor 3 restrains B-cell receptor signaling in normal and malignant B cells.
Expression of miRNA-29 in Pancreatic β Cells Promotes Inflammation and Diabetes via TRAF3.
Enterovirus D68 Protease 2A(pro) Targets TRAF3 To Subvert Host Innate Immune Responses.
Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.
The Nucleoprotein of H7N9 Influenza Virus Positively Regulates TRAF3-Mediated Innate Signaling and Attenuates Viral Virulence in Mice.
TRIM24 facilitates antiviral immunity through mediating K63-linked TRAF3 ubiquitination.
Decreased miR-218-5p Levels as a Serum Biomarker in Bone Metastasis of Prostate Cancer.
TRAF3 Is Required for NF-κB Pathway Activation Mediated by HTLV Tax Proteins.
Dimer-specific immunoprecipitation of active caspase-2 identifies TRAF proteins as novel activators.
The C-Terminal Effector Domain of Non-Structural Protein 1 of Influenza A Virus Blocks IFN-β Production by Targeting TNF Receptor-Associated Factor 3.
Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation.
Capsular Polysaccharide is a Main Component of Mycoplasma ovipneumoniae in the Pathogen-Induced Toll-Like Receptor-Mediated Inflammatory Responses in Sheep Airway Epithelial Cells.
Up-regulation of OLR1 expression by TBC1D3 through activation of TNFα/NF-κB pathway promotes the migration of human breast cancer cells.
Ring finger protein 166 potentiates RNA virus-induced interferon-β production via enhancing the ubiquitination of TRAF3 and TRAF6.
Gu Y, Liang C
International urology and nephrology 2024 May;56(5):1639-1648
International urology and nephrology 2024 May;56(5):1639-1648
Estrogen receptor alpha signaling in dendritic cells modulates autoimmune disease phenotype in mice.
Khaw YM, Anwar S, Zhou J, Kawano T, Lin PC, Otero A, Barakat R, Drnevich J, Takahashi T, Ko CJ, Inoue M
EMBO reports 2023 Mar 6;24(3):e54228
EMBO reports 2023 Mar 6;24(3):e54228
TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion.
Zheng W, Zhou Z, Rui Y, Ye R, Xia F, Guo F, Liu X, Su J, Lou M, Yu XF
Signal transduction and targeted therapy 2023 Feb 24;8(1):79
Signal transduction and targeted therapy 2023 Feb 24;8(1):79
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
Gong X, He Y, Yang D, Yang S, Li J, Zhao H, Chen Q, Ren Q, Zhang B
Bioorganic chemistry 2022 Oct;127:105939
Bioorganic chemistry 2022 Oct;127:105939
TDRD3 is an antiviral restriction factor that promotes IFN signaling with G3BP1.
Deater M, Tamhankar M, Lloyd RE
PLoS pathogens 2022 Jan;18(1):e1010249
PLoS pathogens 2022 Jan;18(1):e1010249
The N6-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response.
Zong X, Xiao X, Shen B, Jiang Q, Wang H, Lu Z, Wang F, Jin M, Min J, Wang F, Wang Y
Nucleic acids research 2021 Jun 4;49(10):5537-5552
Nucleic acids research 2021 Jun 4;49(10):5537-5552
Evolutionary history and functional characterization of Lj-TICAM-a and Lj-TICAM-b formed via lineage-specific tandem duplication in lamprey (Lampetra japonica).
Geng M, Hua Y, Liu Y, Quan J, Hu X, Su P, Li Y, Liu X, Li Q, Zhu T
Genomics 2021 Jul;113(4):2756-2768
Genomics 2021 Jul;113(4):2756-2768
TNF receptor-associated factor 3 restrains B-cell receptor signaling in normal and malignant B cells.
Whillock AL, Ybarra TK, Bishop GA
The Journal of biological chemistry 2021 Jan-Jun;296:100465
The Journal of biological chemistry 2021 Jan-Jun;296:100465
Expression of miRNA-29 in Pancreatic β Cells Promotes Inflammation and Diabetes via TRAF3.
Sun Y, Zhou Y, Shi Y, Zhang Y, Liu K, Liang R, Sun P, Chang X, Tang W, Zhang Y, Li J, Wang S, Zhu Y, Han X
Cell reports 2021 Jan 5;34(1):108576
Cell reports 2021 Jan 5;34(1):108576
Enterovirus D68 Protease 2A(pro) Targets TRAF3 To Subvert Host Innate Immune Responses.
Kang J, Pang Z, Zhou Z, Li X, Liu S, Cheng J, Liu P, Tan W, Wang Z, Wang T
Journal of virology 2021 Jan 13;95(3)
Journal of virology 2021 Jan 13;95(3)
Hypothermic oxygenated perfusion inhibits HECTD3-mediated TRAF3 polyubiquitination to alleviate DCD liver ischemia-reperfusion injury.
Zhou W, Zhong Z, Lin D, Liu Z, Zhang Q, Xia H, Peng S, Liu A, Lu Z, Wang Y, Ye S, Ye Q
Cell death & disease 2021 Feb 24;12(2):211
Cell death & disease 2021 Feb 24;12(2):211
The Nucleoprotein of H7N9 Influenza Virus Positively Regulates TRAF3-Mediated Innate Signaling and Attenuates Viral Virulence in Mice.
Wei Y, Zeng Y, Zhang X, Xu S, Wang Z, Du Y, Zhang B, Lei CQ, Zhu Q
Journal of virology 2020 Nov 23;94(24)
Journal of virology 2020 Nov 23;94(24)
TRIM24 facilitates antiviral immunity through mediating K63-linked TRAF3 ubiquitination.
Zhu Q, Yu T, Gan S, Wang Y, Pei Y, Zhao Q, Pei S, Hao S, Yuan J, Xu J, Hou F, Wu X, Peng C, Wu P, Qin J, Xiao Y
The Journal of experimental medicine 2020 Jul 6;217(7)
The Journal of experimental medicine 2020 Jul 6;217(7)
Decreased miR-218-5p Levels as a Serum Biomarker in Bone Metastasis of Prostate Cancer.
Peng P, Chen T, Wang Q, Zhang Y, Zheng F, Huang S, Tang Y, Yang C, Ding W, Ren D, Huang Z, Guo Y
Oncology research and treatment 2019;42(4):165-185
Oncology research and treatment 2019;42(4):165-185
TRAF3 Is Required for NF-κB Pathway Activation Mediated by HTLV Tax Proteins.
Fochi S, Bergamo E, Serena M, Mutascio S, Journo C, Mahieux R, Ciminale V, Bertazzoni U, Zipeto D, Romanelli MG
Frontiers in microbiology 2019;10:1302
Frontiers in microbiology 2019;10:1302
Dimer-specific immunoprecipitation of active caspase-2 identifies TRAF proteins as novel activators.
Robeson AC, Lindblom KR, Wojton J, Kornbluth S, Matsuura K
The EMBO journal 2018 Jul 13;37(14)
The EMBO journal 2018 Jul 13;37(14)
The C-Terminal Effector Domain of Non-Structural Protein 1 of Influenza A Virus Blocks IFN-β Production by Targeting TNF Receptor-Associated Factor 3.
Qian W, Wei X, Guo K, Li Y, Lin X, Zou Z, Zhou H, Jin M
Frontiers in immunology 2017;8:779
Frontiers in immunology 2017;8:779
Protective Effects of Dioscin against Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Oxidative Stress and Inflammation.
Yao H, Sun Y, Song S, Qi Y, Tao X, Xu L, Yin L, Han X, Xu Y, Li H, Sun H, Peng J
Frontiers in pharmacology 2017;8:120
Frontiers in pharmacology 2017;8:120
Capsular Polysaccharide is a Main Component of Mycoplasma ovipneumoniae in the Pathogen-Induced Toll-Like Receptor-Mediated Inflammatory Responses in Sheep Airway Epithelial Cells.
Jiang Z, Song F, Li Y, Xue D, Deng G, Li M, Liu X, Wang Y
Mediators of inflammation 2017;2017:9891673
Mediators of inflammation 2017;2017:9891673
Up-regulation of OLR1 expression by TBC1D3 through activation of TNFα/NF-κB pathway promotes the migration of human breast cancer cells.
Wang B, Zhao H, Zhao L, Zhang Y, Wan Q, Shen Y, Bu X, Wan M, Shen C
Cancer letters 2017 Nov 1;408:60-70
Cancer letters 2017 Nov 1;408:60-70
Ring finger protein 166 potentiates RNA virus-induced interferon-β production via enhancing the ubiquitination of TRAF3 and TRAF6.
Chen HW, Yang YK, Xu H, Yang WW, Zhai ZH, Chen DY
Scientific reports 2015 Oct 12;5:14770
Scientific reports 2015 Oct 12;5:14770
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Raji cells were subjected to SDS PAGE followed by western blot with 18099-1-AP(TRAF3 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TRAF3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TRAF3. This antibody recognizes human,mouse,rat antigen. The TRAF3 antibody has been validated for the following applications: ELISA, WB, IP analysis.
