Antibody data
- Antibody Data
- Antigen structure
- References [66]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
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- Product number
- 14700-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14700-1-AP, RRID:AB_2233347
- Product name
- GRP94 antibody
- Antibody type
- Polyclonal
- Description
- GRP94 antibody (Cat. #14700-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SIRT3 promotes oxaliplatin sensitivity in hepatocellular carcinoma by promoting ferroptosis through endoplasmic reticulum stress response.
Intelligent delivery of autophagy-targeting chimeric peptides by engineered exosomes for the degradation of α-synuclein.
Rab2A modulates liver fibroblast growth factor 21 (FGF21) expression and systemic metabolism via apolipoprotein B-CREBH signaling.
Chronic ER Stress Triggers Cell-Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia.
Type II Alveolar Epithelial Cells Promote Sepsis-Induced Immunosuppression in Alveolar Macrophages via Exosomal lncRNA Rmrp Release.
TMEDs mediate versatile cargo transport in vesicle-dependent unconventional secretion.
A New Histology-Based Prognostic Index for Acute Lymphoblastic Leukemia: Preliminary Results of the "ALL Urayasu Classification".
Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress.
MYH9 mutations differentially stabilize non-muscle myosin II filaments and induce distinct cellular aggregation phenotypes.
Conformational plasticity of a BiP-GRP94 chaperone complex.
Alterations in PD-L1 succinylation shape anti-tumor immune responses in melanoma.
Oroxylin A inhibits UVB-induced non-melanoma skin cancer by regulating XPA degradation.
Genome-wide screen based on 2DG activated NLRP3 inflammasome reveals the priming signal of TLR2/4 to IKKβ but not IKKα.
Improving Proteostasis of Trafficking-Deficient GABA(A) Receptor Variants by Activating IRE1.
Cochlear endoplasmic reticulum stress causes connexin 26 degradation is involved in age-related hearing loss.
ATF6 Alleviates Endothelial Inflammation Following Extended Hepatectomy Through Inhibition of TRIM10/NF-κB Signaling.
Engineered endoplasmic reticulum-targeting nanodrugs with Piezo1 inhibition and promotion of cell uptake for subarachnoid hemorrhage inflammation repair.
Prognosis and therapeutic significance of IGF-1R-related signaling pathway gene signature in glioma.
Exosomes Derived from Meningitic Escherichia coli-Infected Brain Microvascular Endothelial Cells Facilitate Astrocyte Activation.
Pharmacological chaperones restore proteostasis of epilepsy-associated GABA(A) receptor variants.
Quercetin inhibits endothelial & hepatocellular carcinoma cell crosstalk via reducing extracellular vesicle-mediated VEGFR2 mRNA transfer.
AUY922 improves sensitivity to sunitinib in clear cell renal cell carcinoma based on network pharmacology and in vitro experiments.
ATR induces hepatic lipid metabolism disorder in rats by activating IRE1α/XBP1 signaling pathway.
Proteolysis Targeting Chimeras (PROTACs) based on celastrol induce multiple protein degradation for triple-negative breast cancer treatment.
Rab2A-mediated Golgi-lipid droplet interactions support very-low-density lipoprotein secretion in hepatocytes.
Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage.
Cholesterol induces inflammation and reduces glucose utilization.
HSP90B1-mediated plasma membrane localization of GLUT1 promotes radioresistance of glioblastomas.
FTO-targeted siRNA delivery by MSC-derived exosomes synergistically alleviates dopaminergic neuronal death in Parkinson's disease via m6A-dependent regulation of ATM mRNA.
Lipid metabolism of plasma-derived small extracellular vesicles in COVID-19 convalescent patients.
Exosomal miR-222-3p contributes to castration-resistant prostate cancer by activating mTOR signaling.
Initial and ongoing tobacco smoking elicits vascular damage and distinct inflammatory response linked to neurodegeneration.
N(6)-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis.
4-phenylbutyric acid re-trafficking hERG/G572R channel protein by modulating the endoplasmic reticulum stress-associated chaperones and endoplasmic reticulum-associated degradation gene.
Pharmacological chaperones restore proteostasis of epilepsy-associated GABA(A) receptor variants.
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Severe Acute Respiratory Syndrome Coronavirus 2 ORF8 Protein Inhibits Type I Interferon Production by Targeting HSP90B1 Signaling.
Proteome and Glycoproteome Analyses Reveal the Protein N-Linked Glycosylation Specificity of STT3A and STT3B.
HSP90B1 overexpression is associated with poor prognosis in tongue squamous cell carcinoma.
Peste des petits ruminants virus induces ERS-mediated autophagy to promote virus replication.
TSG-6 released from adipose stem cells-derived small extracellular vesicle protects against spinal cord ischemia reperfusion injury by inhibiting endoplasmic reticulum stress.
ATF6-Mediated Unfolded Protein Response Facilitates Adeno-associated Virus 2 (AAV2) Transduction by Releasing the Suppression of the AAV Receptor on Endoplasmic Reticulum Stress.
Exercise-derived peptide protects against pathological cardiac remodeling.
Comparative analysis of ChAdOx1 nCoV-19 and Ad26.COV2.S SARS-CoV-2 vector vaccines.
miRNA-mRNA Regulatory Network Reveals miRNAs in HCT116 in Response to Folic Acid Deficiency via Regulating Vital Genes of Endoplasmic Reticulum Stress Pathway.
Xbp1s-Ddit3 promotes MCT-induced pulmonary hypertension.
Novel Role of HAX-1 in Neurons Protection After Spinal Cord Injury Involvement of IRE-1.
TRPV4 contributes to ER stress: Relation to apoptosis in the MPP(+)-induced cell model of Parkinson's disease.
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes.
A Translocation Pathway for Vesicle-Mediated Unconventional Protein Secretion.
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo.
Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3 and Mediating αVβ3/Src/E2F1 Signaling.
Co-downregulation of GRP78 and GRP94 Induces Apoptosis and Inhibits Migration in Prostate Cancer Cells.
Oxidative stress in the neurodegenerative brain following lifetime exposure to lead in rats: Changes in lifespan profiles.
GRP94 overexpression as an indicator of unfavorable outcomes in breast cancer patients.
Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway.
PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Dimethylarginine Dimethylaminohydrolase 1 Protects Against High-Fat Diet-Induced Hepatic Steatosis and Insulin Resistance in Mice.
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Endoplasmic reticulum (ER) stress protein responses in relation to spatio-temporal dynamics of astroglial responses to status epilepticus in rats.
Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
Reduction in heat shock protein 90 correlates to neuronal vulnerability in the rat piriform cortex following status epilepticus.
Upregulation of phosphorylated HSP27, PRDX2, GRP75, GRP78 and GRP94 in acquired middle ear cholesteatoma growth.
Cx31.1 acts as a tumour suppressor in non-small cell lung cancer (NSCLC) cell lines through inhibition of cell proliferation and metastasis.
Proteomics-based identification of a group of apoptosis-related proteins and biomarkers in gastric cancer.
Xu Y, Ma C, Xu X, Tu J, Chen X, Yang X, Sun D, Liu S, Wan Y, Qin L, Gu W, Qian H
Pathology, research and practice 2026 May;281:156400
Pathology, research and practice 2026 May;281:156400
Intelligent delivery of autophagy-targeting chimeric peptides by engineered exosomes for the degradation of α-synuclein.
Zeng Y, Lv Z, Liang J, Wu Y, Han L
Acta biomaterialia 2026 May;215:288-301
Acta biomaterialia 2026 May;215:288-301
Rab2A modulates liver fibroblast growth factor 21 (FGF21) expression and systemic metabolism via apolipoprotein B-CREBH signaling.
Chen ZY, Xu M, Chen S, Chen L
The Journal of biological chemistry 2026 Jan;302(1):110977
The Journal of biological chemistry 2026 Jan;302(1):110977
Chronic ER Stress Triggers Cell-Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia.
Zhou Y, Zhong Z, Hu P, Wang W, Song Y, Yang N, He F, Li Y, Sa Q, Yang Y, Sun Q, Yang T, Zhang B, Chen D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e11573
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e11573
Type II Alveolar Epithelial Cells Promote Sepsis-Induced Immunosuppression in Alveolar Macrophages via Exosomal lncRNA Rmrp Release.
Liu C, Xuan W, Cao S, Jia H, Wu Q, Tan X, Wang Q, Li X, Ding L, Xiong Y, Zhao M, Zheng L, Xi Y, Tan J, Li R, Zhang X, Liu W, Wu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e00376
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e00376
TMEDs mediate versatile cargo transport in vesicle-dependent unconventional secretion.
Zheng J, Wang H, Sun Y, Chang P, Deng X, Zhang L, Zhu L, Zhu K, Peng D, Deng H, Zhang M, Ge L
The Journal of cell biology 2026 Jan 5;225(1)
The Journal of cell biology 2026 Jan 5;225(1)
A New Histology-Based Prognostic Index for Acute Lymphoblastic Leukemia: Preliminary Results of the "ALL Urayasu Classification".
Mitsumori T, Nitta H, Takizawa H, Iizuka-Honma H, Furuya C, Maruo S, Fujishiro M, Tomita S, Hashizume A, Sawada T, Miyake K, Okubo M, Sekiguchi Y, Noguchi M
Journal of clinical medicine 2026 Jan 17;15(2)
Journal of clinical medicine 2026 Jan 17;15(2)
Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress.
Qiu QQ, Zhang N, Xu YY, Qin JW, Yu GF, Song XR
Molecular medicine reports 2026 Feb;33(2)
Molecular medicine reports 2026 Feb;33(2)
MYH9 mutations differentially stabilize non-muscle myosin II filaments and induce distinct cellular aggregation phenotypes.
Llorente-González C, Mustafina K, Asensio-Juárez G, Garrido-Casado M, Talayero VC, Pérez-Díaz R, Ramos-Solano H, Sellers JR, Chinthalapudi K, Wiseman PW, Heissler SM, Vicente-Manzanares M
Cellular and molecular life sciences : CMLS 2026 Feb 28;83(1)
Cellular and molecular life sciences : CMLS 2026 Feb 28;83(1)
Conformational plasticity of a BiP-GRP94 chaperone complex.
Brenner JC, Zirden LC, Buzuk L, Almeida-Hernandez Y, Radzuweit L, Diamantino J, Kaschani F, Kaiser M, Sanchez-Garcia E, Poepsel S, Hellerschmied D
Nature structural & molecular biology 2025 Oct;32(10):1947-1958
Nature structural & molecular biology 2025 Oct;32(10):1947-1958
Alterations in PD-L1 succinylation shape anti-tumor immune responses in melanoma.
Liang L, Kuang X, He Y, Zhu L, Lau P, Li X, Luo D, Gong L, Zhou W, Zhang F, Liang X, Li Z, Hu B, Liu D, Ding T, Li H, Zhao S, Su J, Hung MC, Liu J, Liu H, Chen X
Nature genetics 2025 Mar;57(3):680-693
Nature genetics 2025 Mar;57(3):680-693
Oroxylin A inhibits UVB-induced non-melanoma skin cancer by regulating XPA degradation.
Dou R, Sun J, Yang H, Zheng Y, Yuan K, Qiang L, Ma R, Liu Y
Chinese journal of natural medicines 2025 Jun;23(6):742-753
Chinese journal of natural medicines 2025 Jun;23(6):742-753
Genome-wide screen based on 2DG activated NLRP3 inflammasome reveals the priming signal of TLR2/4 to IKKβ but not IKKα.
Gao H, Sun M, Gao H, Sun Y, Chen W, Dong N
International immunopharmacology 2025 Jan 3;145:113781
International immunopharmacology 2025 Jan 3;145:113781
Improving Proteostasis of Trafficking-Deficient GABA(A) Receptor Variants by Activating IRE1.
Fu X, Wang YJ, Lee K, Ahn LY, Chen X, Harvey BT, Wang M, Seibert H, Zhang PP, Guerrero A, Schaffer AE, Richards CI, Wiseman RL, Kelly JW, Mu TW
ACS chemical neuroscience 2025 Dec 3;16(23):4429-4445
ACS chemical neuroscience 2025 Dec 3;16(23):4429-4445
Cochlear endoplasmic reticulum stress causes connexin 26 degradation is involved in age-related hearing loss.
Bai X, Liao B, Hu WH, Wang MQ, Sun Y, Chen XB, Xu K
iScience 2025 Dec 19;28(12):113891
iScience 2025 Dec 19;28(12):113891
ATF6 Alleviates Endothelial Inflammation Following Extended Hepatectomy Through Inhibition of TRIM10/NF-κB Signaling.
Shi CC, Yang DJ, Bai Y, Zhou B, Sun YH, Xu XR, Guo WZ, Zhang SJ, Liang Y, Jin Y, Shi JH
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70933
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70933
Engineered endoplasmic reticulum-targeting nanodrugs with Piezo1 inhibition and promotion of cell uptake for subarachnoid hemorrhage inflammation repair.
Zhang X, Jiang E, Fu W, Wang Y, Wang Y, Fang Z, Zhang Z, Duan J, Zeng J, Yan Y, Liu F
Journal of nanobiotechnology 2025 Apr 5;23(1):274
Journal of nanobiotechnology 2025 Apr 5;23(1):274
Prognosis and therapeutic significance of IGF-1R-related signaling pathway gene signature in glioma.
Liu Z, Yang L, Wu W, Chen Z, Xie Z, Shi D, Cai N, Zhuo S
Frontiers in cell and developmental biology 2024;12:1375030
Frontiers in cell and developmental biology 2024;12:1375030
Exosomes Derived from Meningitic Escherichia coli-Infected Brain Microvascular Endothelial Cells Facilitate Astrocyte Activation.
Yang R, Qu X, Zhi S, Wang J, Fu J, Tan C, Chen H, Wang X
Molecular neurobiology 2024 Sep;61(9):7195-7210
Molecular neurobiology 2024 Sep;61(9):7195-7210
Pharmacological chaperones restore proteostasis of epilepsy-associated GABA(A) receptor variants.
Wang YJ, Seibert H, Ahn LY, Schaffer AE, Mu TW
Pharmacological research 2024 Oct;208:107356
Pharmacological research 2024 Oct;208:107356
Quercetin inhibits endothelial & hepatocellular carcinoma cell crosstalk via reducing extracellular vesicle-mediated VEGFR2 mRNA transfer.
Xiong W, Zheng B, Liu D, Pu M, Zhou S, Deng Y
Molecular carcinogenesis 2024 Nov;63(11):2254-2268
Molecular carcinogenesis 2024 Nov;63(11):2254-2268
AUY922 improves sensitivity to sunitinib in clear cell renal cell carcinoma based on network pharmacology and in vitro experiments.
Chen Z, Jia X, Cai Y, Song Y, Tong Y, Cheng S, Liu M
Heliyon 2024 Jul 30;10(14):e34834
Heliyon 2024 Jul 30;10(14):e34834
ATR induces hepatic lipid metabolism disorder in rats by activating IRE1α/XBP1 signaling pathway.
Qian H, Zhao Y, Wang Y, Zhao H, Cui J, Wang Z, Ye H, Fang X, Ge Z, Zhang Y, Ye L
Toxicology 2024 Jan;501:153696
Toxicology 2024 Jan;501:153696
Proteolysis Targeting Chimeras (PROTACs) based on celastrol induce multiple protein degradation for triple-negative breast cancer treatment.
Gan X, Wang F, Luo J, Zhao Y, Wang Y, Yu C, Chen J
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Jan 1;192:106624
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Jan 1;192:106624
Rab2A-mediated Golgi-lipid droplet interactions support very-low-density lipoprotein secretion in hepatocytes.
Xu M, Chen ZY, Li Y, Li Y, Guo G, Dai RZ, Ni N, Tao J, Wang HY, Chen QL, Wang H, Zhou H, Yang YN, Chen S, Chen L
The EMBO journal 2024 Dec;43(24):6383-6409
The EMBO journal 2024 Dec;43(24):6383-6409
Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage.
Gong K, Xue C, Feng Z, Pan R, Wang M, Chen S, Chen Y, Guan Y, Dai L, Zhang S, Jiang L, Li L, Wang B, Yin Z, Ma L, Iwakiri Y, Tang J, Liao C, Chen H, Duan Y
Nature communications 2024 Aug 10;15(1):6845
Nature communications 2024 Aug 10;15(1):6845
Cholesterol induces inflammation and reduces glucose utilization.
Hong P, Wang Q, Chen G
Open medicine (Warsaw, Poland) 2023;18(1):20230701
Open medicine (Warsaw, Poland) 2023;18(1):20230701
HSP90B1-mediated plasma membrane localization of GLUT1 promotes radioresistance of glioblastomas.
Li Y, Ge Y, Zhao M, Ding F, Wang X, Shi Z, Ge X, Wang X, Qian X
Journal of biomedical research 2023 Sep 28;37(5):326-339
Journal of biomedical research 2023 Sep 28;37(5):326-339
FTO-targeted siRNA delivery by MSC-derived exosomes synergistically alleviates dopaminergic neuronal death in Parkinson's disease via m6A-dependent regulation of ATM mRNA.
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Journal of translational medicine 2023 Sep 22;21(1):652
Journal of translational medicine 2023 Sep 22;21(1):652
Lipid metabolism of plasma-derived small extracellular vesicles in COVID-19 convalescent patients.
Xiao W, Huang Q, Luo P, Tan X, Xia H, Wang S, Sun Y, Wang Z, Ma Y, Zhang J, Jin Y
Scientific reports 2023 Oct 3;13(1):16642
Scientific reports 2023 Oct 3;13(1):16642
Exosomal miR-222-3p contributes to castration-resistant prostate cancer by activating mTOR signaling.
Wang W, Kong P, Feng K, Liu C, Gong X, Sun T, Duan X, Sang Y, Jiang Y, Li X, Zhang L, Tao Z, Liu W
Cancer science 2023 Nov;114(11):4252-4269
Cancer science 2023 Nov;114(11):4252-4269
Initial and ongoing tobacco smoking elicits vascular damage and distinct inflammatory response linked to neurodegeneration.
Garza AP, Morton L, Pállinger É, Buzás EI, Schreiber S, Schott BH, Dunay IR
Brain, behavior, & immunity - health 2023 Mar;28:100597
Brain, behavior, & immunity - health 2023 Mar;28:100597
N(6)-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis.
Chen B, Huang Y, He S, Yu P, Wu L, Peng H
Cell chemical biology 2023 Feb 16;30(2):144-158.e10
Cell chemical biology 2023 Feb 16;30(2):144-158.e10
4-phenylbutyric acid re-trafficking hERG/G572R channel protein by modulating the endoplasmic reticulum stress-associated chaperones and endoplasmic reticulum-associated degradation gene.
Tang W, Cai D, Fu Y, Zheng Z, Huang X, Khouzam RN, Song Y, Lian J
Journal of thoracic disease 2023 Aug 31;15(8):4472-4485
Journal of thoracic disease 2023 Aug 31;15(8):4472-4485
Pharmacological chaperones restore proteostasis of epilepsy-associated GABA(A) receptor variants.
Wang YJ, Seibert H, Ahn LY, Schaffer AE, Mu TW
bioRxiv : the preprint server for biology 2023 Apr 19;
bioRxiv : the preprint server for biology 2023 Apr 19;
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Liu C, Lu J, Yuan T, Xie L, Zhang L
Scientific reports 2023 Apr 14;13(1):6126
Scientific reports 2023 Apr 14;13(1):6126
Severe Acute Respiratory Syndrome Coronavirus 2 ORF8 Protein Inhibits Type I Interferon Production by Targeting HSP90B1 Signaling.
Chen J, Lu Z, Yang X, Zhou Y, Gao J, Zhang S, Huang S, Cai J, Yu J, Zhao W, Zhang B
Frontiers in cellular and infection microbiology 2022;12:899546
Frontiers in cellular and infection microbiology 2022;12:899546
Proteome and Glycoproteome Analyses Reveal the Protein N-Linked Glycosylation Specificity of STT3A and STT3B.
Wen P, Chen J, Zuo C, Gao X, Fujita M, Yang G
Cells 2022 Sep 6;11(18)
Cells 2022 Sep 6;11(18)
HSP90B1 overexpression is associated with poor prognosis in tongue squamous cell carcinoma.
Chen YB, Feng YQ, Chen S
Journal of stomatology, oral and maxillofacial surgery 2022 Nov;123(6):e833-e838
Journal of stomatology, oral and maxillofacial surgery 2022 Nov;123(6):e833-e838
Peste des petits ruminants virus induces ERS-mediated autophagy to promote virus replication.
Wen B, Yang L, Guo J, Chang W, Wei S, Yu S, Qi X, Xue Q, Wang J
Veterinary microbiology 2022 Jul;270:109451
Veterinary microbiology 2022 Jul;270:109451
TSG-6 released from adipose stem cells-derived small extracellular vesicle protects against spinal cord ischemia reperfusion injury by inhibiting endoplasmic reticulum stress.
Lu X, Lv C, Zhao Y, Wang Y, Li Y, Ji C, Wang Z, Ye W, Yu S, Bai J, Cai W
Stem cell research & therapy 2022 Jul 13;13(1):291
Stem cell research & therapy 2022 Jul 13;13(1):291
ATF6-Mediated Unfolded Protein Response Facilitates Adeno-associated Virus 2 (AAV2) Transduction by Releasing the Suppression of the AAV Receptor on Endoplasmic Reticulum Stress.
Cui M, Zhao Q, Wang J, Si Y, Cheng S, Ding W
Journal of virology 2022 Feb 9;96(3):e0110321
Journal of virology 2022 Feb 9;96(3):e0110321
Exercise-derived peptide protects against pathological cardiac remodeling.
Yin A, Yuan R, Xiao Q, Zhang W, Xu K, Yang X, Yang W, Xu L, Wang X, Zhuang F, Li Y, Cai Z, Sun Z, Zhou B, He B, Shen L
EBioMedicine 2022 Aug;82:104164
EBioMedicine 2022 Aug;82:104164
Comparative analysis of ChAdOx1 nCoV-19 and Ad26.COV2.S SARS-CoV-2 vector vaccines.
Michalik S, Siegerist F, Palankar R, Franzke K, Schindler M, Reder A, Seifert U, Cammann C, Wesche J, Steil L, Hentschker C, Gesell-Salazar M, Reisinger E, Beer M, Endlich N, Greinacher A, Völker U
Haematologica 2022 Apr 1;107(4):947-957
Haematologica 2022 Apr 1;107(4):947-957
miRNA-mRNA Regulatory Network Reveals miRNAs in HCT116 in Response to Folic Acid Deficiency via Regulating Vital Genes of Endoplasmic Reticulum Stress Pathway.
Lu L, Zhao H, Liu J, Zhang Y, Wang X
BioMed research international 2021;2021:6650181
BioMed research international 2021;2021:6650181
Xbp1s-Ddit3 promotes MCT-induced pulmonary hypertension.
Jiang H, Ding D, He Y, Li X, Xu Y, Liu X
Clinical science (London, England : 1979) 2021 Nov 12;135(21):2467-2481
Clinical science (London, England : 1979) 2021 Nov 12;135(21):2467-2481
Novel Role of HAX-1 in Neurons Protection After Spinal Cord Injury Involvement of IRE-1.
Chen J, Yang S, Wu C, Cui Z, Wan Y, Xu G, Bao G, Zhang J, Chen C, Song D
Neurochemical research 2020 Oct;45(10):2302-2311
Neurochemical research 2020 Oct;45(10):2302-2311
TRPV4 contributes to ER stress: Relation to apoptosis in the MPP(+)-induced cell model of Parkinson's disease.
Liu N, Liu J, Wen X, Bai L, Shao R, Bai J
Life sciences 2020 Nov 15;261:118461
Life sciences 2020 Nov 15;261:118461
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, Shao X, Song N, Zhao Y, Li H, Yang G, Xu C, Wei C
Redox biology 2020 May;32:101514
Redox biology 2020 May;32:101514
Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes.
Han P, Hanlon D, Arshad N, Lee JS, Tatsuno K, Robinson E, Filler R, Sobolev O, Cote C, Rivera-Molina F, Toomre D, Fahmy T, Edelson R
Science advances 2020 Mar;6(11):eaaz1580
Science advances 2020 Mar;6(11):eaaz1580
A Translocation Pathway for Vesicle-Mediated Unconventional Protein Secretion.
Zhang M, Liu L, Lin X, Wang Y, Li Y, Guo Q, Li S, Sun Y, Tao X, Zhang D, Lv X, Zheng L, Ge L
Cell 2020 Apr 30;181(3):637-652.e15
Cell 2020 Apr 30;181(3):637-652.e15
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo.
Liao Z, Luo R, Li G, Song Y, Zhan S, Zhao K, Hua W, Zhang Y, Wu X, Yang C
Theranostics 2019;9(14):4084-4100
Theranostics 2019;9(14):4084-4100
Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3 and Mediating αVβ3/Src/E2F1 Signaling.
Pan TJ, Li LX, Zhang JW, Yang ZS, Shi DM, Yang YK, Wu WZ
Journal of Cancer 2019;10(20):4777-4792
Journal of Cancer 2019;10(20):4777-4792
Co-downregulation of GRP78 and GRP94 Induces Apoptosis and Inhibits Migration in Prostate Cancer Cells.
Lu T, Wang Y, Xu K, Zhou Z, Gong J, Zhang Y, Gong H, Dai Q, Yang J, Xiong B, Song Z, Yang G
Open life sciences 2019 Jan;14:384-391
Open life sciences 2019 Jan;14:384-391
Oxidative stress in the neurodegenerative brain following lifetime exposure to lead in rats: Changes in lifespan profiles.
Feng C, Liu S, Zhou F, Gao Y, Li Y, Du G, Chen Y, Jiao H, Feng J, Zhang Y, Bo D, Li Z, Fan G
Toxicology 2019 Jan 1;411:101-109
Toxicology 2019 Jan 1;411:101-109
GRP94 overexpression as an indicator of unfavorable outcomes in breast cancer patients.
Liu S, Li R, Zuo S, Luo R, Fang W, Xie Y
International journal of clinical and experimental pathology 2018;11(6):3061-3067
International journal of clinical and experimental pathology 2018;11(6):3061-3067
Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway.
Liu M, Li Y, Liang B, Li Z, Jiang Z, Chu C, Yang J
International journal of molecular medicine 2018 Apr;41(4):1867-1876
International journal of molecular medicine 2018 Apr;41(4):1867-1876
PCSK9 regulates apoptosis in human lung adenocarcinoma A549 cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Xu X, Cui Y, Cao L, Zhang Y, Yin Y, Hu X
Experimental and therapeutic medicine 2017 May;13(5):1993-1999
Experimental and therapeutic medicine 2017 May;13(5):1993-1999
Dimethylarginine Dimethylaminohydrolase 1 Protects Against High-Fat Diet-Induced Hepatic Steatosis and Insulin Resistance in Mice.
Li T, Feng R, Zhao C, Wang Y, Wang J, Liu S, Cao J, Wang H, Wang T, Guo Y, Lu Z
Antioxidants & redox signaling 2017 Apr 10;26(11):598-609
Antioxidants & redox signaling 2017 Apr 10;26(11):598-609
PACE4 regulates apoptosis in human prostate cancer cells via endoplasmic reticulum stress and mitochondrial signaling pathways.
Yao Z, Sun B, Hong Q, Yan J, Mu D, Li J, Sheng H, Guo H
Drug design, development and therapy 2015;9:5911-23
Drug design, development and therapy 2015;9:5911-23
Endoplasmic reticulum (ER) stress protein responses in relation to spatio-temporal dynamics of astroglial responses to status epilepticus in rats.
Ko AR, Kim JY, Hyun HW, Kim JE
Neuroscience 2015 Oct 29;307:199-214
Neuroscience 2015 Oct 29;307:199-214
Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
Xu D, Su C, Song X, Shi Q, Fu J, Hu L, Xia X, Song E, Song Y
Chemical research in toxicology 2015 Jun 15;28(6):1326-37
Chemical research in toxicology 2015 Jun 15;28(6):1326-37
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14700-1-AP(HSP90B1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunofluorescent analysis of A431 cells, using HSP90B1 antibody 14700-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 14700-1-AP(HSP90B1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 14700-1-AP(HSP90B1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue