DCABY-4141

IGFBP6 antibody from Creative Diagnostics

Western blot

Recommended by provider

ELISA

Recommended by provider

Provider product page for DCABY-4141

Antibody Data

Product number

DCABY-4141

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABY-4141, RRID:AB_2496213

Product name

Anti-IGFBP6 monoclonal antibody, clone 220322

Provider product page

Antibody type

Monoclonal

Description

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. ALS (Acid Labile Subunit) is a liver-derived protein that exists in a ternary complex with Insulin-like Growth Factor (IGF)-binding Protein-3 (IGFBP-3) or IGFBP-5, and either IGF-I or IGF-II. ALS increases the half-life of IGF/IGFBP complexes in circulation.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

220322

Vial size

500  mg

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month from date of receipt, 2 to 8°C, reconstituted. 6 months from date of receipt, -20 to -70 °C, reconstituted.

Handling

The antibody solution should be gently mixed before use.