Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunohistochemistry [7]
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- Product number
- NBP1-89772 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-89772, RRID:AB_11032938
- Product name
- Rabbit Polyclonal Metallothionein-3 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human Metallothionein-3 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Metallothionein 3 Controls the Phenotype and Metabolic Programming of Alternatively Activated Macrophages.
The stoichiometric transition from Zn6Cu1-metallothionein to Zn7-metallothionein underlies the up-regulation of metallothionein (MT) expression: quantitative analysis of MT-metal load in eye cells.
Chowdhury D, Alrefai H, Landero Figueroa JA, Candor K, Porollo A, Fecher R, Divanovic S, Deepe GS Jr, Subramanian Vignesh K
Cell reports 2019 Jun 25;27(13):3873-3886.e7
Cell reports 2019 Jun 25;27(13):3873-3886.e7
The stoichiometric transition from Zn6Cu1-metallothionein to Zn7-metallothionein underlies the up-regulation of metallothionein (MT) expression: quantitative analysis of MT-metal load in eye cells.
Alvarez L, Gonzalez-Iglesias H, Garcia M, Ghosh S, Sanz-Medel A, Coca-Prados M
The Journal of biological chemistry 2012 Aug 17;287(34):28456-69
The Journal of biological chemistry 2012 Aug 17;287(34):28456-69
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Metallothionein-3 Antibody [NBP1-89772] - Staining of human cerebral cortex shows high expression.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Metallothionein-3 Antibody [NBP1-89772] - Staining of human pancreas shows low expression as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Metallothionein-3 Antibody [NBP1-89772] - Analysis in human cerebral cortex and pancreas tissues. Corresponding Metallothionein-3 RNA-seq data are presented for the same tissues.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Metallothionein-3 Antibody [NBP1-89772] - Staining of human cerebellum shows very strong cytoplasmic positivity in astrocytes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Metallothionein-3 Antibody [NBP1-89772] - Staining of human cerebral cortex shows strong cytoplasmic positivity in astrocytes.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Metallothionein-3 Antibody [NBP1-89772] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Metallothionein-3 Antibody [NBP1-89772] - Staining of human tonsil shows no positivity in non-germinal center cells as expected.