DPABH-26620

antibody from Creative Diagnostics

Targeting: CCNH CycH, p34, p37

Western blot (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

DPABH-26620

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-26620, RRID:AB_2506888

Product name

Rabbit Anti-Human CCNH Polyclonal Antibody

Antibody type

Polyclonal

Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010]

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50ul, 100ul

Storage

Store at 4°C. Avoid freeze / thaw cycles.