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- Antibody Data
- Antigen structure
- References [6]
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- Product number
- ABIN374159 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Engulfment and Cell Motility 1 (ELMO1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide from C-Terminus of the protein sequence according to NP_055615.8, NP_569709.1, NP_001034548.1 Genename: ELMO1
- Description
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Zebrafish
- Host
- Goat
- Antigen sequence
PKEPSNYDFVYDCN- Epitope
- C-Term
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The Rac1 regulator ELMO controls basal body migration and docking in multiciliated cells through interaction with Ezrin.
The Rac1 regulator ELMO1 controls vascular morphogenesis in zebrafish.
Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis.
ELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion.
Elmo1 inhibits ubiquitylation of Dock180.
A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling.
Epting D, Slanchev K, Boehlke C, Hoff S, Loges NT, Yasunaga T, Indorf L, Nestel S, Lienkamp SS, Omran H, Kuehn EW, Ronneberger O, Walz G, Kramer-Zucker A
Development (Cambridge, England) 2015 Jan 1;142(1):174-84
Development (Cambridge, England) 2015 Jan 1;142(1):174-84
The Rac1 regulator ELMO1 controls vascular morphogenesis in zebrafish.
Epting D, Wendik B, Bennewitz K, Dietz CT, Driever W, Kroll J
Circulation research 2010 Jul 9;107(1):45-55
Circulation research 2010 Jul 9;107(1):45-55
Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis.
Sai J, Raman D, Liu Y, Wikswo J, Richmond A
The Journal of biological chemistry 2008 Sep 26;283(39):26538-47
The Journal of biological chemistry 2008 Sep 26;283(39):26538-47
ELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion.
Jarzynka MJ, Hu B, Hui KM, Bar-Joseph I, Gu W, Hirose T, Haney LB, Ravichandran KS, Nishikawa R, Cheng SY
Cancer research 2007 Aug 1;67(15):7203-11
Cancer research 2007 Aug 1;67(15):7203-11
Elmo1 inhibits ubiquitylation of Dock180.
Makino Y, Tsuda M, Ichihara S, Watanabe T, Sakai M, Sawa H, Nagashima K, Hatakeyama S, Tanaka S
Journal of cell science 2006 Mar 1;119(Pt 5):923-32
Journal of cell science 2006 Mar 1;119(Pt 5):923-32
A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling.
Côté JF, Motoyama AB, Bush JA, Vuori K
Nature cell biology 2005 Aug;7(8):797-807
Nature cell biology 2005 Aug;7(8):797-807
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