NBP2-29408
antibody from Novus Biologicals
Targeting: MUC1
ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM
Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Flow cytometry [1]
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Validation data
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- Product number
- NBP2-29408 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal MUC1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. In Western blotting, it recognizes proteins in MW range of 265-400kDa, identified as different glycoforms of EMA. This MAb reacts with the DTRP epitope in the tandem repeats. The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C.
Submitted references Magnetic-Based Enrichment of Rare Cells from High Concentrated Blood Samples.
Wu J, Raba K, Guglielmi R, Behrens B, Van Dalum G, Flügen G, Koch A, Patel S, Knoefel WT, Stoecklein NH, Neves RPL
Cancers 2020 Apr 10;12(4)
Cancers 2020 Apr 10;12(4)
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MUC1 Antibody (GP1.4) [NBP2-29408] - Formalin-paraffin human breast cancer stained with EMA Ab (GP1.4). Note cytoplasmic and membrane staining.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: MUC1 Antibody (GP1.4) [NBP2-29408] - Analysis using the PE conjugate of NBP2-29408. Staining of NHBE cells with anti-MUC1 antibody [PE] (yellow line).