19976-1-AP
antibody from Proteintech Group
Targeting: MUC1
ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM
Antibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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Validation data
Reference
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- Product number
- 19976-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19976-1-AP, RRID:AB_10646428
- Product name
- MUC1/CA15-3 N-terminal antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MUC1/CA15-3 N-terminal antibody (Cat. #19976-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Aptamer-bivalent-cholesterol-mediated proximity entropy-driven exosomal protein reporter for tumor diagnosis.
A novel ex vivo lung cancer model based on bioengineered rat lungs.
Establishment and characterization of a multi-drug resistant cell line for canine mammary tumors.
Ginsenoside Rg3 Ameliorates DSS-Induced Colitis by Inhibiting NLRP3 Inflammasome Activation and Regulating Microbial Homeostasis.
Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor.
LINC02535/miR-30a-5p/GALNT3 axis contributes to lung adenocarcinoma progression via the NF- κ B signaling pathway.
Integration of Dual Targeting and Dual Therapeutic Modules Endows Self-Assembled Nanoparticles with Anti-Tumor Growth and Metastasis Functions.
YBX1 Enhances Metastasis and Stemness by Transcriptionally Regulating MUC1 in Lung Adenocarcinoma.
Role of EIF4G1 network in non-small cell lung cancers (NSCLC) cell survival and disease progression.
Aptamer-Peptide Conjugates as Targeted Chemosensitizers for Breast Cancer Treatment.
Integrative Genomic Analysis of Gemcitabine Resistance in Pancreatic Cancer by Patient-derived Xenograft Models.
GalNAc-T3 and MUC1, a combined predictor of prognosis and recurrence in solitary pulmonary adenocarcinoma initially diagnosed as malignant solitary pulmonary nodule (≤ 3 cm).
CircWHSC1 promotes ovarian cancer progression by regulating MUC1 and hTERT through sponging miR-145 and miR-1182.
Effects of Levonorgestrel and progesterone on Oviductal physiology in mammals.
Endogenous and exogenous galectin-3 promote the adhesion of tumor cells with low expression of MUC1 to HUVECs through upregulation of N-cadherin and CD44.
Core 3 mucin-type O-glycan restoration in colorectal cancer cells promotes MUC1/p53/miR-200c-dependent epithelial identity.
Expression of MUC1 and CD176 (Thomsen-Friedenreich antigen) in papillary thyroid carcinomas.
Fan Z, Zhou J, Shu Q, Dong Y, Li Y, Zhang T, Bai G, Yu H, Lu F, Li J, Zhao X
Biosensors & bioelectronics 2024 May 1;251:116104
Biosensors & bioelectronics 2024 May 1;251:116104
A novel ex vivo lung cancer model based on bioengineered rat lungs.
Mizoguchi S, Tsuchiya T, Doi R, Obata T, Iwatake M, Hashimoto S, Matsumoto H, Yukawa H, Hayashi H, Li TS, Yamamoto K, Matsumoto K, Miyazaki T, Tomoshige K, Nagayasu T
Frontiers in bioengineering and biotechnology 2023;11:1179830
Frontiers in bioengineering and biotechnology 2023;11:1179830
Establishment and characterization of a multi-drug resistant cell line for canine mammary tumors.
Zhou C, Lin Z, Li X, Zhang D, Song P
Frontiers in veterinary science 2023;10:1129756
Frontiers in veterinary science 2023;10:1129756
Ginsenoside Rg3 Ameliorates DSS-Induced Colitis by Inhibiting NLRP3 Inflammasome Activation and Regulating Microbial Homeostasis.
Liu D, Tian Q, Liu K, Ren F, Liu G, Zhou J, Yuan L, Fang Z, Zou B, Wang S
Journal of agricultural and food chemistry 2023 Feb 8;
Journal of agricultural and food chemistry 2023 Feb 8;
Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor.
Giang LH, Wu KS, Lee WC, Chu SS, Do AD, Changou CA, Tran HM, Hsieh TH, Chen HH, Hsieh CL, Sung SY, Yu AL, Yen Y, Wong TT, Chang CC
Journal of experimental & clinical cancer research : CR 2023 Dec 20;42(1):346
Journal of experimental & clinical cancer research : CR 2023 Dec 20;42(1):346
LINC02535/miR-30a-5p/GALNT3 axis contributes to lung adenocarcinoma progression via the NF- κ B signaling pathway.
Li Y, Zhao J, Zhang W, Wang A, Jiao M, Cai X, Zhu J, Liu Z, Huang JA
Cell cycle (Georgetown, Tex.) 2022 Dec;21(23):2455-2470
Cell cycle (Georgetown, Tex.) 2022 Dec;21(23):2455-2470
Integration of Dual Targeting and Dual Therapeutic Modules Endows Self-Assembled Nanoparticles with Anti-Tumor Growth and Metastasis Functions.
Chen B, Dong X, Dong X, Wang Q, Wu M, Wu J, Lou X, Xia F, Wang W, Dai J, Wang S
International journal of nanomedicine 2021;16:1361-1376
International journal of nanomedicine 2021;16:1361-1376
YBX1 Enhances Metastasis and Stemness by Transcriptionally Regulating MUC1 in Lung Adenocarcinoma.
Xie Q, Zhao S, Liu W, Cui Y, Li F, Li Z, Guo T, Yu W, Guo W, Deng W, Gu C
Frontiers in oncology 2021;11:702491
Frontiers in oncology 2021;11:702491
Role of EIF4G1 network in non-small cell lung cancers (NSCLC) cell survival and disease progression.
Del Valle L, Dai L, Lin HY, Lin Z, Chen J, Post SR, Qin Z
Journal of cellular and molecular medicine 2021 Mar;25(6):2795-2805
Journal of cellular and molecular medicine 2021 Mar;25(6):2795-2805
Aptamer-Peptide Conjugates as Targeted Chemosensitizers for Breast Cancer Treatment.
Tan Y, Li Y, Qu YX, Su Y, Peng Y, Zhao Z, Fu T, Wang XQ, Tan W
ACS applied materials & interfaces 2021 Mar 3;13(8):9436-9444
ACS applied materials & interfaces 2021 Mar 3;13(8):9436-9444
Integrative Genomic Analysis of Gemcitabine Resistance in Pancreatic Cancer by Patient-derived Xenograft Models.
Yang G, Guan W, Cao Z, Guo W, Xiong G, Zhao F, Feng M, Qiu J, Liu Y, Zhang MQ, You L, Zhang T, Zhao Y, Gu J
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Jun 15;27(12):3383-3396
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Jun 15;27(12):3383-3396
GalNAc-T3 and MUC1, a combined predictor of prognosis and recurrence in solitary pulmonary adenocarcinoma initially diagnosed as malignant solitary pulmonary nodule (≤ 3 cm).
Xie Q, Li F, Zhao S, Guo T, Li Z, Fang L, Wang S, Liu W, Gu C
Human cell 2020 Oct;33(4):1252-1263
Human cell 2020 Oct;33(4):1252-1263
CircWHSC1 promotes ovarian cancer progression by regulating MUC1 and hTERT through sponging miR-145 and miR-1182.
Zong ZH, Du YP, Guan X, Chen S, Zhao Y
Journal of experimental & clinical cancer research : CR 2019 Oct 30;38(1):437
Journal of experimental & clinical cancer research : CR 2019 Oct 30;38(1):437
Effects of Levonorgestrel and progesterone on Oviductal physiology in mammals.
Li C, Zhang HY, Liang Y, Xia W, Zhu Q, Zhang D, Huang Z, Liang GL, Xue RH, Qi H, He XQ, Yuan JJ, Tan YJ, Huang HF, Zhang J
Reproductive biology and endocrinology : RB&E 2018 Jun 20;16(1):59
Reproductive biology and endocrinology : RB&E 2018 Jun 20;16(1):59
Endogenous and exogenous galectin-3 promote the adhesion of tumor cells with low expression of MUC1 to HUVECs through upregulation of N-cadherin and CD44.
Cao Z, Hao Z, Xin M, Yu L, Wang L, Zhang Y, Zhang X, Guo X
Laboratory investigation; a journal of technical methods and pathology 2018 Dec;98(12):1642-1656
Laboratory investigation; a journal of technical methods and pathology 2018 Dec;98(12):1642-1656
Core 3 mucin-type O-glycan restoration in colorectal cancer cells promotes MUC1/p53/miR-200c-dependent epithelial identity.
Ye J, Wei X, Shang Y, Pan Q, Yang M, Tian Y, He Y, Peng Z, Chen L, Chen W, Wang R
Oncogene 2017 Nov 16;36(46):6391-6407
Oncogene 2017 Nov 16;36(46):6391-6407
Expression of MUC1 and CD176 (Thomsen-Friedenreich antigen) in papillary thyroid carcinomas.
Zhan XX, Zhao B, Diao C, Cao Y, Cheng RC
Endocrine pathology 2015 Mar;26(1):21-6
Endocrine pathology 2015 Mar;26(1):21-6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A431 cells were subjected to SDS PAGE followed by western blot with 19976-1-AP(CA15-3,MUC1 antibody) at dilution of 1:1500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 19976-1-AP(CA15-3,MUC1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 19976-1-AP(CA15-3,MUC1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MUC1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human MUC1. This antibody recognizes human antigen. The MUC1 antibody has been validated for the following applications: ELISA, WB, FC, IHC analysis.