Ab116370

antibody from Aladdin Scientific

Targeting: MUC1 ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM

Antibody data

Submit

Validation data

Product number: Ab116370 - Provider product page
Provider: Aladdin Scientific
Product name: MUC1 Mouse mAb
Antibody type: Monoclonal
Description: Mouse anti Human MUC1 antibody; , Monoclonal (C1), could be used for WB and so on.Application:WB: 0.01-2 µg/mLProtein FunctionThe alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: AA 1034~1151
Antibody clone number: C1
Vial size: 100_l,10_l,1ml,20_l,50_l
Concentration: Lot by Lot
Storage: Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

MUC1 protein structure - Ab116370 shown in red.