RA0516

antibody from Oursmab

Targeting: MUC1 ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0516

Provider

Oursmab

Product name

Gatipotuzumab (Biosimilar Reference Antibody) (MUC1)

Antibody type

Monoclonal

Description

Gatipotuzumab is an investigational, humanized monoclonal antibody developed for the treatment of solid tumors, with a focus on adenocarcinomas such as ovarian, breast, and endometrial cancers. It represents a novel approach due to its unique target specificity. Gatipotuzumab is engineered to recognize a specific tumor-associated glycoform of the MUC1 glycoprotein. By binding with high affinity to this aberrantly glycosylated form of MUC1, which is selectively expressed on cancer cells, the antibody aims to direct immune-mediated killing specifically to the tumor. Its proposed mechanisms of action include antibody-dependent cellular cytotoxicity (ADCC) and potentially the inhibition of tumor-promoting signaling pathways.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Gatipotuzumab (Biosimilar Reference Antibody) (MUC1)-RA0516-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Gatipotuzumab (Biosimilar Reference Antibody) (MUC1)-RA0516 in a linear range of 0.18¨C15 ng/mL.