Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 13869-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13869-1-AP, RRID:AB_2215349
- Product name
- VPS41 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated VPS41 antibody (Cat. #13869-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Atractylenolide I inhibits angiogenesis and reverses sunitinib resistance in clear cell renal cell carcinoma through ATP6V0D2-mediated autophagic degradation of EPAS1/HIF2α.
Downregulation of MYBL1 in endothelial cells contributes to atherosclerosis by repressing PLEKHM1-inducing autophagy.
C9orf72-catalyzed GTP loading of Rab39A enables HOPS-mediated membrane tethering and fusion in mammalian autophagy.
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.
ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation.
The topology of the lymphotoxin β receptor that accumulates upon endolysosomal dysfunction dictates the NF-κB signaling outcome.
Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.
Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L.
Li Q, Zeng K, Chen Q, Han C, Wang X, Li B, Miao J, Zheng B, Liu J, Yuan X, Liu B
Autophagy 2025 Mar;21(3):619-638
Autophagy 2025 Mar;21(3):619-638
Downregulation of MYBL1 in endothelial cells contributes to atherosclerosis by repressing PLEKHM1-inducing autophagy.
Ding SA, Liu H, Zheng R, Ge Y, Fu Z, Mei J, Tang M
Cell biology and toxicology 2024 May 27;40(1):40
Cell biology and toxicology 2024 May 27;40(1):40
C9orf72-catalyzed GTP loading of Rab39A enables HOPS-mediated membrane tethering and fusion in mammalian autophagy.
Zhang S, Tong M, Zheng D, Huang H, Li L, Ungermann C, Pan Y, Luo H, Lei M, Tang Z, Fu W, Chen S, Liu X, Zhong Q
Nature communications 2023 Oct 11;14(1):6360
Nature communications 2023 Oct 11;14(1):6360
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.
Zheng W, Chen Q, Liu H, Zeng L, Zhou Y, Liu X, Bai Y, Zhang J, Pan Y, Shao C
Autophagy 2023 Mar;19(3):839-857
Autophagy 2023 Mar;19(3):839-857
ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation.
Miao G, Zhao H, Li Y, Ji M, Chen Y, Shi Y, Bi Y, Wang P, Zhang H
Developmental cell 2021 Feb 22;56(4):427-442.e5
Developmental cell 2021 Feb 22;56(4):427-442.e5
The topology of the lymphotoxin β receptor that accumulates upon endolysosomal dysfunction dictates the NF-κB signaling outcome.
Banach-Orłowska M, Jastrzębski K, Cendrowski J, Maksymowicz M, Wojciechowska K, Korostyński M, Moreau D, Gruenberg J, Miaczynska M
Journal of cell science 2018 Nov 21;131(22)
Journal of cell science 2018 Nov 21;131(22)
Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.
van der Kant R, Jonker CT, Wijdeven RH, Bakker J, Janssen L, Klumperman J, Neefjes J
The Journal of biological chemistry 2015 Dec 18;290(51):30280-90
The Journal of biological chemistry 2015 Dec 18;290(51):30280-90
Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L.
van der Kant R, Fish A, Janssen L, Janssen H, Krom S, Ho N, Brummelkamp T, Carette J, Rocha N, Neefjes J
Journal of cell science 2013 Aug 1;126(Pt 15):3462-74
Journal of cell science 2013 Aug 1;126(Pt 15):3462-74
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The VPS41 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human VPS41. This antibody recognizes human antigen. The VPS41 antibody has been validated for the following applications: ELISA, WB analysis.