Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- H00079977-A01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00079977-A01, RRID:AB_2113415
- Product name
- Mouse Polyclonal GRHL2 Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified. GRHL2 - grainyhead-like 2 (Drosophila)
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Grainyhead-like 2 (GRHL2) knockout abolishes oral cancer development through reciprocal regulation of the MAP kinase and TGF-β signaling pathways.
hTERT peptide fragment GV1001 demonstrates radioprotective and antifibrotic effects through suppression of TGF‑β signaling.
Human Papillomavirus 16 E6 Induces FoxM1B in Oral Keratinocytes through GRHL2.
Grainyhead-like 2 regulates epithelial plasticity and stemness in oral cancer cells.
Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer.
Grainyhead-like 2 (GRHL2) inhibits keratinocyte differentiation through epigenetic mechanism.
Grainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5'-CpG island in normal human keratinocytes.
Regulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cells.
Chen W, Kang KL, Alshaikh A, Varma S, Lin YL, Shin KH, Kim R, Wang CY, Park NH, Walentin K, Schmidt-Ott KM, Kang MK
Oncogenesis 2018 May 8;7(5):38
Oncogenesis 2018 May 8;7(5):38
hTERT peptide fragment GV1001 demonstrates radioprotective and antifibrotic effects through suppression of TGF‑β signaling.
Chen W, Shin KH, Kim S, Shon WJ, Kim RH, Park NH, Kang MK
International journal of molecular medicine 2018 Jun;41(6):3211-3220
International journal of molecular medicine 2018 Jun;41(6):3211-3220
Human Papillomavirus 16 E6 Induces FoxM1B in Oral Keratinocytes through GRHL2.
Chen W, Shimane T, Kawano S, Alshaikh A, Kim SY, Chung SH, Kim RH, Shin KH, Walentin K, Park NH, Schmidt-Ott KM, Kang MK
Journal of dental research 2018 Jul;97(7):795-802
Journal of dental research 2018 Jul;97(7):795-802
Grainyhead-like 2 regulates epithelial plasticity and stemness in oral cancer cells.
Chen W, Yi JK, Shimane T, Mehrazarin S, Lin YL, Shin KH, Kim RH, Park NH, Kang MK
Carcinogenesis 2016 May;37(5):500-10
Carcinogenesis 2016 May;37(5):500-10
Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer.
Werner S, Frey S, Riethdorf S, Schulze C, Alawi M, Kling L, Vafaizadeh V, Sauter G, Terracciano L, Schumacher U, Pantel K, Assmann V
The Journal of biological chemistry 2013 Aug 9;288(32):22993-3008
The Journal of biological chemistry 2013 Aug 9;288(32):22993-3008
Grainyhead-like 2 (GRHL2) inhibits keratinocyte differentiation through epigenetic mechanism.
Chen W, Xiao Liu Z, Oh JE, Shin KH, Kim RH, Jiang M, Park NH, Kang MK
Cell death & disease 2012 Dec 20;3:e450
Cell death & disease 2012 Dec 20;3:e450
Grainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5'-CpG island in normal human keratinocytes.
Chen W, Dong Q, Shin KH, Kim RH, Oh JE, Park NH, Kang MK
The Journal of biological chemistry 2010 Dec 24;285(52):40852-63
The Journal of biological chemistry 2010 Dec 24;285(52):40852-63
Regulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cells.
Kang X, Chen W, Kim RH, Kang MK, Park NH
Oncogene 2009 Jan 29;28(4):565-74
Oncogene 2009 Jan 29;28(4):565-74
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: GRHL2 Antibody [H00079977-A01] - Detection against Immunogen (37.11 KDa) .