Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- NB100-74543 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-74543, RRID:AB_1049752
- Product name
- Rabbit Polyclonal SREBP2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. SREBP2
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ug
- Concentration
- 1 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Clinical relevance of cholesterol homeostasis genes in colorectal cancer.
Activation of LXR Receptors and Inhibition of TRAP1 Causes Synthetic Lethality in Solid Tumors.
Proteasome inhibition protects against diet-induced gallstone formation through modulation of cholesterol and bile acid homeostasis.
Senescence marker protein-30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis.
Ascorbic acid deficiency affects genes for oxidation-reduction and lipid metabolism in livers from SMP30/GNL knockout mice.
Peroxisome Proliferator-activated receptor γ activation by ligands and dephosphorylation induces proprotein convertase subtilisin kexin type 9 and low density lipoprotein receptor expression.
Persistence of Mycobacterium avium subsp. paratuberculosis at a farm-scale biogas plant supplied with manure from paratuberculosis-affected dairy cattle.
Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism.
High copper selectively alters lipid metabolism and cell cycle machinery in the mouse model of Wilson disease.
Sharma B, Gupta V, Dahiya D, Kumar H, Vaiphei K, Agnihotri N
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Oct;1864(10):1314-1327
Biochimica et biophysica acta. Molecular and cell biology of lipids 2019 Oct;1864(10):1314-1327
Activation of LXR Receptors and Inhibition of TRAP1 Causes Synthetic Lethality in Solid Tumors.
Nguyen TTT, Ishida CT, Shang E, Shu C, Bianchetti E, Karpel-Massler G, Siegelin MD
Cancers 2019 Jun 7;11(6)
Cancers 2019 Jun 7;11(6)
Proteasome inhibition protects against diet-induced gallstone formation through modulation of cholesterol and bile acid homeostasis.
Lee EJ, Kim MH, Kim YR, Park JW, Park WJ
International journal of molecular medicine 2018 Mar;41(3):1715-1723
International journal of molecular medicine 2018 Mar;41(3):1715-1723
Senescence marker protein-30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis.
Kondo Y, Masutomi H, Noda Y, Ozawa Y, Takahashi K, Handa S, Maruyama N, Shimizu T, Ishigami A
FEBS open bio 2014;4:522-32
FEBS open bio 2014;4:522-32
Ascorbic acid deficiency affects genes for oxidation-reduction and lipid metabolism in livers from SMP30/GNL knockout mice.
Takahashi K, Kishimoto Y, Konishi T, Fujita Y, Ito M, Shimokado K, Maruyama N, Ishigami A
Biochimica et biophysica acta 2014 Jul;1840(7):2289-98
Biochimica et biophysica acta 2014 Jul;1840(7):2289-98
Peroxisome Proliferator-activated receptor γ activation by ligands and dephosphorylation induces proprotein convertase subtilisin kexin type 9 and low density lipoprotein receptor expression.
Duan Y, Chen Y, Hu W, Li X, Yang X, Zhou X, Yin Z, Kong D, Yao Z, Hajjar DP, Liu L, Liu Q, Han J
The Journal of biological chemistry 2012 Jul 6;287(28):23667-77
The Journal of biological chemistry 2012 Jul 6;287(28):23667-77
Persistence of Mycobacterium avium subsp. paratuberculosis at a farm-scale biogas plant supplied with manure from paratuberculosis-affected dairy cattle.
Slana I, Pribylova R, Kralova A, Pavlik I
Applied and environmental microbiology 2011 May;77(9):3115-9
Applied and environmental microbiology 2011 May;77(9):3115-9
Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism.
Rabot S, Membrez M, Bruneau A, Gérard P, Harach T, Moser M, Raymond F, Mansourian R, Chou CJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Dec;24(12):4948-59
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 Dec;24(12):4948-59
High copper selectively alters lipid metabolism and cell cycle machinery in the mouse model of Wilson disease.
Huster D, Purnat TD, Burkhead JL, Ralle M, Fiehn O, Stuckert F, Olson NE, Teupser D, Lutsenko S
The Journal of biological chemistry 2007 Mar 16;282(11):8343-55
The Journal of biological chemistry 2007 Mar 16;282(11):8343-55
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: SREBP2 Antibody [NB100-74543] - Analysis of 25 ug of mouse liver (lane 1), rat liver (lane 2) and HepG2 (lane 3) cell lysates.