Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 18701-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18701-1-AP, RRID:AB_2154286
- Product name
- NUMB antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NUMB antibody (Cat. #18701-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Therapeutic targeting m6A-guided miR-146a-5p signaling contributes to the melittin-induced selective suppression of bladder cancer.
IFT20 Mediates the Transport of Cell Migration Regulators From the Trans-Golgi Network to the Plasma Membrane in Breast Cancer Cells.
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
The polarity protein Par3 regulates APP trafficking and processing through the endocytic adaptor protein Numb.
Musashi2 predicts poor prognosis and invasion in hepatocellular carcinoma by driving epithelial-mesenchymal transition.
Regulation of lung cancer metastasis by Klf4-Numb-like signaling.
Yan R, Dai W, Wu R, Huang H, Shu M
Cancer letters 2022 May 28;534:215615
Cancer letters 2022 May 28;534:215615
IFT20 Mediates the Transport of Cell Migration Regulators From the Trans-Golgi Network to the Plasma Membrane in Breast Cancer Cells.
Yang H, Zhang F, Long H, Lin Y, Liao J, Xia H, Huang K
Frontiers in cell and developmental biology 2021;9:632198
Frontiers in cell and developmental biology 2021;9:632198
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
Yin LL, Wen XM, Li M, Xu YM, Zhao XF, Li J, Wang XW
Oncology letters 2018 Nov;16(5):6283-6292
Oncology letters 2018 Nov;16(5):6283-6292
The polarity protein Par3 regulates APP trafficking and processing through the endocytic adaptor protein Numb.
Sun M, Asghar SZ, Zhang H
Neurobiology of disease 2016 Sep;93:1-11
Neurobiology of disease 2016 Sep;93:1-11
Musashi2 predicts poor prognosis and invasion in hepatocellular carcinoma by driving epithelial-mesenchymal transition.
He L, Zhou X, Qu C, Hu L, Tang Y, Zhang Q, Liang M, Hong J
Journal of cellular and molecular medicine 2014 Jan;18(1):49-58
Journal of cellular and molecular medicine 2014 Jan;18(1):49-58
Regulation of lung cancer metastasis by Klf4-Numb-like signaling.
Vaira V, Faversani A, Martin NM, Garlick DS, Ferrero S, Nosotti M, Kissil JL, Bosari S, Altieri DC
Cancer research 2013 Apr 15;73(8):2695-705
Cancer research 2013 Apr 15;73(8):2695-705
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 18701-1-AP(NUMB antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NUMB antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human NUMB. This antibody recognizes human, mouse antigen. The NUMB antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 18701-1-AP(NUMB antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 18701-1-AP(NUMB antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue