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- References [5]
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- Product number
- 60137-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60137-1-Ig, RRID:AB_10598775
- Product name
- NUMB antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated NUMB antibody (Cat. #60137-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2G12B7
- Vial size
- 20ul, 150ul
Submitted references BM-MSCs overexpressing the Numb enhance the therapeutic effect on cholestatic liver fibrosis by inhibiting the ductular reaction.
Stabilizing vimentin phosphorylation inhibits stem-like cell properties and metastasis of hybrid epithelial/mesenchymal carcinomas.
Different roles of Numb-p72 and Numb-p65 on the trafficking of metabotropic glutamate receptor 5.
Hepatic stem cell Numb gene is a potential target of Huang Qi Decoction against cholestatic liver fibrosis.
Numb deficiency causes impaired trafficking of mGlu5 in neurons and autistic-like behaviors.
Xu YN, Xu W, Zhang X, Wang DY, Zheng XR, Liu W, Chen JM, Chen GF, Liu CH, Liu P, Mu YP
Stem cell research & therapy 2023 Mar 20;14(1):45
Stem cell research & therapy 2023 Mar 20;14(1):45
Stabilizing vimentin phosphorylation inhibits stem-like cell properties and metastasis of hybrid epithelial/mesenchymal carcinomas.
Kuburich NA, den Hollander P, Castaneda M, Pietilä M, Tang X, Batra H, Martínez-Peña F, Visal TH, Zhou T, Demestichas BR, Dontula RV, Liu JY, Maddela JJ, Padmanabhan RS, Phi LTH, Rosolen MJ, Sabapathy T, Kumar D, Giancotti FG, Lairson LL, Raso MG, Soundararajan R, Mani SA
Cell reports 2023 Dec 26;42(12):113470
Cell reports 2023 Dec 26;42(12):113470
Different roles of Numb-p72 and Numb-p65 on the trafficking of metabotropic glutamate receptor 5.
Wang N, Wang DD, Hou X, Li X, Shen Y
Molecular biology reports 2021 Jan;48(1):595-600
Molecular biology reports 2021 Jan;48(1):595-600
Hepatic stem cell Numb gene is a potential target of Huang Qi Decoction against cholestatic liver fibrosis.
Xu W, Xu YN, Zhang X, Xu Y, Jian X, Chen JM, Chen GF, Zhang H, Liu P, Mu YP
Scientific reports 2020 Oct 15;10(1):17486
Scientific reports 2020 Oct 15;10(1):17486
Numb deficiency causes impaired trafficking of mGlu5 in neurons and autistic-like behaviors.
Wang N, Wang DD, Shen Y
Neuroscience letters 2019 Aug 10;707:134291
Neuroscience letters 2019 Aug 10;707:134291
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NUMB antibody from Proteintech is a mouse monoclonal antibody to a peptide of human NUMB. This antibody recognizes human, mouse antigen. The NUMB antibody has been validated for the following applications: ELISA, WB analysis.
