orb67106

antibody from Biorbyt

Targeting: NUMB C14orf41

Western blot (Data presented on provider website)

Antibody Data

Product number

orb67106

Provider

Biorbyt

Product name

NUMB antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal to NUMB.NUMB is a membrane-bound protein that has been shown to associate with EPS15, LNX1, andNOTCH1. NUMB is required throughout embryonic neurogenesis to maintain neural progenitor cells,also called radial glial cells GCs), by allowing their daughter cells to choose progenitor overneuronal cell fate. NUMB is not required for the proliferation of neural progenitor cells before the onsetof neurogenesis. NUMB is also involved postnatally in the subventricular zone (SVZ) neurogenesis byregulating SVZ neuroblasts survival and ependymal wall integrity. In addition, NUMB may mediatelocal repair of brain ventricular wall damage.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Vial size

100 ul

Storage

-20°C