130-10029-100

antibody from RayBiotech, Inc.

Targeting: INHBA

ELISA (Recommended by provider)

Antibody Data

Product number

130-10029-100

Provider

RayBiotech, Inc.

Product name

Rabbit Anti-Human Inhibin

Antibody type

Polyclonal

Antigen

Synthetic peptide derived from Human inhibin beta.

Description

Inhibin, which belong to the TGF-? protein superfamily, inhibits FSH production and GnRH release from the hypothalamus. Inhibins are dimeric peptide hormones produced by female ovarian granulose cells and male Sertoli cells as well as a variety of other tissues. Inhibins have two isoforms, A and B, with the same alpha subunit but different beta subunits. Inhibin A is a dimer of alpha and beta A subunits, inhibin B is a dimer of alpha and beta B subunits. Inhibins can inhibit the production of follicle-stimulating hormone (FSH) by the pituitary gland. In addition, Inhibins also play a role in the control of gametogenesis, and embryonic and fetal development. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbitt serum by ammonium sulphate precipitation followed by Protein A/G affinity chromatography.

Reactivity

Human

Host

Rabbit

Antigen sequence

This antibody was produced from a r
abbit immunized with the immunogen.
The IgG fraction was purified from
rabbitt serum by ammonium sulphate
precipitation followed by Protein
A/G affinity chromatography.


Isotype

IgG

Vial size

100 µg

Handling

Supplied as lyophilized and purified antibody originally containing PBS, without Preservative Stabilizers, such as Sodium Azide. Its final concentration is indicated on the shipping vial. The antibody is stable for at least years from the data of receipt when stored at -20°C to -70°C. Reconstituted antibody (suggesting with sterile PBS) can also be aliquotted and stored frozen at -20°C to -70°C in a manual defrost freezer for months without detectable loss activity. Upon reconstitution, the antibody can also be stored over months at 4°C. Please avoid freeze-thaw cycles.