BS8500

antibody from Bioworld Technology, Inc

Targeting: INHBA

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS8500

Provider

Bioworld Technology, Inc

Product name

Inhibin ÉÇ A polyclonal antibody

Antibody type

Polyclonal

Antigen

Inhibin beta A chain; Activin beta-A chain; Erythroid differentiation protein; EDF; INHBA; Inhibin ³Úa; InhibinÉÇ A; InhibinÉÇ-A

Description

The TGFÉÇ superfamily is composed of numerous growth and differentiation factors, including transforming growth factor ÉÇ (TGFÉÇ) 1, 2 and 3; growth/differentiation factor (GDF) 1 through 8; Mullerian inhibiting substance (MIS); bone morphogenic protein (BMP) 2 through 8; glial cell line-derived neurotrophic factor (GDNF); Inhibins (Ï«, ÉÇ-A, ÉÇ-B and ÉÇ-C), Lefty and Nodal. Members of the TGFÉÇ superfamily are involved in embryonic development and adult tissue homeostasis. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins and activins are involved in regulating a number of functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, Insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Activins oppose the funtions of Inhibins. Inhibins are predominantly expressed in liver, uterus and ovary tissue. Inhibin A, a dimer of Ï« and ÉÇ-A, and Inhibin B, a dimer of Ï« and ÉÇ-B, have been shown to inhibit the secretion of follicle stimulating hormone. Inhibin ÉÇ-C forms a homodimer and its expression is predominant in adult liver.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.