MAB3381

antibody from R&D Systems

Targeting: INHBA

ELISA (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

MAB3381

Provider

R&D Systems

Product name

Anti-Human/Mouse/Rat Activin A βA subunit Monoclonal Antibody (Clone 69403)

Antibody type

Monoclonal

Antigen

Chinese hamster ovary cell line CHO-derived recombinant human Activin A

Description

Protein A or G purified from hybridoma culture supernatant

Reactivity

Human, Mouse, Rat

Host

Mouse

Isotype

IgG

Vial size

500 µg

References

Submitted references

Activin A programs the differentiation of human TFH cells.

Locci M, Wu JE, Arumemi F, Mikulski Z, Dahlberg C, Miller AT, Crotty S
Nature immunology 2016 Aug;17(8):976-84

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Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor Prognosis.

Bufalino A, Cervigne NK, de Oliveira CE, Fonseca FP, Rodrigues PC, Macedo CC, Sobral LM, Miguel MC, Lopes MA, Paes Leme AF, Lambert DW, Salo TA, Kowalski LP, Graner E, Coletta RD
PloS one 2015;10(8):e0136599

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Adipose Stromal Cell Contact with Endothelial Cells Results in Loss of Complementary Vasculogenic Activity Mediated by Induction of Activin A.

Merfeld-Clauss S, Lupov IP, Lu H, March KL, Traktuev DO
Stem cells (Dayton, Ohio) 2015 Oct;33(10):3039-51

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Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers.

Sierra-Filardi E, Puig-Kröger A, Blanco FJ, Nieto C, Bragado R, Palomero MI, Bernabéu C, Vega MA, Corbí AL
Blood 2011 May 12;117(19):5092-101

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Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappaB.

Alexander S, Watt F, Sawaji Y, Hermansson M, Saklatvala J
Arthritis and rheumatism 2007 Nov;56(11):3715-25

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The neuroprotective effect of Activin A and B: implication for neurodegenerative diseases.

Kupershmidt L, Amit T, Bar-Am O, Youdim MB, Blumenfeld Z
Journal of neurochemistry 2007 Nov;103(3):962-71

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Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal.

Greber B, Lehrach H, Adjaye J
Stem cells (Dayton, Ohio) 2007 Feb;25(2):455-64

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Requirement of Smad3 for mast cell growth.

Funaba M, Nakaya K, Ikeda T, Murakami M, Tsuchida K, Sugino H
Cellular immunology 2006 Mar;240(1):47-52

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N-cadherin is regulated by activin A and associated with tumor aggressiveness in esophageal carcinoma.

Yoshinaga K, Inoue H, Utsunomiya T, Sonoda H, Masuda T, Mimori K, Tanaka Y, Mori M
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Sep 1;10(17):5702-7