APR04127G

antibody from Leading Biology

Targeting: EPOR

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

APR04127G

Provider

Leading Biology

Product name

EPOR Antibody (Center)

Antibody type

Polyclonal

Description

This gene encodes the erythropoietin receptor which is amember of the cytokine receptor family. Upon erythropoietinbinding, this receptor activates Jak2 tyrosine kinase whichactivates different intracellular pathways including: Ras/MAPkinase, phosphatidylinositol 3-kinase and STAT transcriptionfactors. The stimulated erythropoietin receptor appears to have arole in erythroid cell survival. Defects in the erythropoietinreceptor may produce erythroleukemia and familial erythrocytosis.Dysregulation of this gene may affect the growth of certain tumors.Alternate splicing results in multiple transcript variants.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.