MAB307

antibody from R&D Systems

Targeting: EPOR

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

MAB307

Provider

R&D Systems

Product name

Anti-Human Erythropoietin R Monoclonal Antibody (Clone 38409)

Antibody type

Monoclonal

Antigen

Mouse myeloma cell line NS0-derived recombinant human Erythropoietin R, Pro26-Pro250

Description

Protein A or G purified from ascites

Reactivity

Human

Host

Mouse

Antigen sequence

P19235


Isotype

IgG

Vial size

500 µg

References

Submitted references

Functional EpoR pathway utilization is not detected in primary tumor cells isolated from human breast, non-small cell lung, colorectal, and ovarian tumor tissues.

Patterson SD, Rossi JM, Paweletz KL, Fitzpatrick VD, Begley CG, Busse L, Elliott S, McCaffery I
PloS one 2015;10(3):e0122149

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JAK2V617F activates Lu/BCAM-mediated red cell adhesion in polycythemia vera through an EpoR-independent Rap1/Akt pathway.

De Grandis M, Cambot M, Wautier MP, Cassinat B, Chomienne C, Colin Y, Wautier JL, Le Van Kim C, El Nemer W
Blood 2013 Jan 24;121(4):658-65

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Soluble erythropoietin receptor contributes to erythropoietin resistance in end-stage renal disease.

Khankin EV, Mutter WP, Tamez H, Yuan HT, Karumanchi SA, Thadhani R
PloS one 2010 Feb 16;5(2):e9246

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Functional and immunochemical characterisation of different antibodies against the erythropoietin receptor.

Kirkeby A, van Beek J, Nielsen J, Leist M, Helboe L
Journal of neuroscience methods 2007 Aug 15;164(1):50-8