Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN394905 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Apoptosis Inhibitor 5 (API5) (AA 400-504) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 400-504
- Isotype
- IgG
- Antibody clone number
- 1C2
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Pim-2 activates API-5 to inhibit the apoptosis of hepatocellular carcinoma cells through NF-kappaB pathway.
The antiapoptotic protein AAC-11 interacts with and regulates Acinus-mediated DNA fragmentation.
A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.
Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target.
Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo.
Ren K, Zhang W, Shi Y, Gong J
Pathology oncology research : POR 2010 Jun;16(2):229-37
Pathology oncology research : POR 2010 Jun;16(2):229-37
The antiapoptotic protein AAC-11 interacts with and regulates Acinus-mediated DNA fragmentation.
Rigou P, Piddubnyak V, Faye A, Rain JC, Michel L, Calvo F, Poyet JL
The EMBO journal 2009 Jun 3;28(11):1576-88
The EMBO journal 2009 Jun 3;28(11):1576-88
A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.
Need AC, Attix DK, McEvoy JM, Cirulli ET, Linney KL, Hunt P, Ge D, Heinzen EL, Maia JM, Shianna KV, Weale ME, Cherkas LF, Clement G, Spector TD, Gibson G, Goldstein DB
Human molecular genetics 2009 Dec 1;18(23):4650-61
Human molecular genetics 2009 Dec 1;18(23):4650-61
Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target.
Wang Y, Lee AT, Ma JZ, Wang J, Ren J, Yang Y, Tantoso E, Li KB, Ooi LL, Tan P, Lee CG
The Journal of biological chemistry 2008 May 9;283(19):13205-15
The Journal of biological chemistry 2008 May 9;283(19):13205-15
Functional identification of Api5 as a suppressor of E2F-dependent apoptosis in vivo.
Morris EJ, Michaud WA, Ji JY, Moon NS, Rocco JW, Dyson NJ
PLoS genetics 2006 Nov 17;2(11):e196
PLoS genetics 2006 Nov 17;2(11):e196
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- WB
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- WB
Supportive validation
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- ELISA
Supportive validation
- Submitted by
- antibodies-online (provider)
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- Experimental details
- IHC