BS8523

antibody from Bioworld Technology, Inc
Targeting: TUFM EF-TuMT, EFTu
Provider product page for BS8523
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8523 - Provider product page
Provider
Bioworld Technology, Inc
Product name
EF Tu polyclonal antibody
Antibody type
Polyclonal
Antigen
Elongation factor Tu, mitochondrial; EFTu; P43; TUFM
Description
EF-Ts, also known as TSFM (Ts translation elongation factor, mitochondrial) or COXPD3, is a 325 amino acid protein that is one of 13 mitochondrial-encoded proteins that work together during the elongation phase of protein biosynthesis on the ribosome. Expressed ubiquitously with highest levels present in liver, kidney and skeletal muscle, EF-Ts associates with EF-Tu, a multidomain GTPase with essential functions in translation, and, via this interaction, facilitates the exchange of GDP for GTP, thereby inducing protein elongation. Mutations in the gene encoding EF-Ts are the cause of combined oxidative phosphorylation deficiency type 3 (COXPD3), a condition characterized by defects in the mitochondrial oxidative phosphorylation system and often characterized by severe metabolic acidosis with encephalomyopathy or with hypertrophic cardiomyopathy. Multiple isoforms of EF-Ts exist due to alternative splicing events.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TUFM protein structure - BS8523 shown in red.