Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS60278 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- YAF2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human YAF2.
- Description
- Members of the myeloctyomatosis viral oncogene homologue (Myc) family, which include c-Myc, N-Myc and L-Myc, encode transcription factors that play a role in the acceleration of cell cycle progression and cell growth, inhibition of cell differentiation, and initiation of programmed cell death (apoptosis). YY1-associated factor 2, also known as YAF2, is a 180 amino acid protein that binds to c-Myc and inhibits c-Myc-mediated pathways. It also binds to N-Myc, enhancing N-Myc-dependent transcriptional activation. Furthermore, YAF2 interacts with YY1 to antagonize YY1 transactivation of muscle-specific promoters. Localized to the nucleus, YAF2 contains an N-terminal C2-X10-C2 zinc finger and exists as two isoforms.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of YAF2 pAb at 1:500 dilutionLane1:Jurkat whole cell lysateLane2:Raw264.7 whole cell lysateLane3:H9C2 whole cell lysate