PAB2352
antibody from Abnova Corporation
Targeting: NCOR1
hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- PAB2352 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2352, RRID:AB_1577611
- Product name
- NCOR1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of NCOR1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The nuclear receptor corepressor (N-CoR) modulates basal and activated transcription of genes controlled by retinoic acid.
The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor.
CHD1 associates with NCoR and histone deacetylase as well as with RNA splicing proteins.
Loinder K, Söderström M
The Journal of steroid biochemistry and molecular biology 2003 Jan;84(1):15-21
The Journal of steroid biochemistry and molecular biology 2003 Jan;84(1):15-21
The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor.
Ishizuka T, Lazar MA
Molecular and cellular biology 2003 Aug;23(15):5122-31
Molecular and cellular biology 2003 Aug;23(15):5122-31
CHD1 associates with NCoR and histone deacetylase as well as with RNA splicing proteins.
Tai HH, Geisterfer M, Bell JC, Moniwa M, Davie JR, Boucher L, McBurney MW
Biochemical and biophysical research communications 2003 Aug 15;308(1):170-6
Biochemical and biophysical research communications 2003 Aug 15;308(1):170-6
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The NCOR1 polyclonal antibody (Cat # PAB2352) is used in Western blot to detect NCOR1 in mouse thymus tissue lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with the NCOR1 polyclonal antibody (Cat # PAB2352) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)