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- Product number
- ABIN952019 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-ECSIT Homolog (Drosophila) (ECSIT) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- Other
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 0.1 mg
Submitted references Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly.
Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis.
ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway.
Vogel RO, Janssen RJ, van den Brand MA, Dieteren CE, Verkaart S, Koopman WJ, Willems PH, Pluk W, van den Heuvel LP, Smeitink JA, Nijtmans LG
Genes & development 2007 Mar 1;21(5):615-24
Genes & development 2007 Mar 1;21(5):615-24
Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis.
Xiao C, Shim JH, Klüppel M, Zhang SS, Dong C, Flavell RA, Fu XY, Wrana JL, Hogan BL, Ghosh S
Genes & development 2003 Dec 1;17(23):2933-49
Genes & development 2003 Dec 1;17(23):2933-49
ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway.
Kopp E, Medzhitov R, Carothers J, Xiao C, Douglas I, Janeway CA, Ghosh S
Genes & development 1999 Aug 15;13(16):2059-71
Genes & development 1999 Aug 15;13(16):2059-71
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of ECSIT Antibody (C-term) Cat.-No AP51359PU-N in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the ECSIT antibody detected the ECSIT protein (arrow).
