ABIN257786
antibody from antibodies-online
Targeting: ELMO2
CED-12, CED12, ELMO-2, FLJ11656, KIAA1834
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN257786 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Engulfment and Cell Motility 2 (ELMO2) (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human
- Host
- Goat
- Epitope
- C-Term
- Vial size
- 0.1 mg
- Storage
- Store at -20°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock.
Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion.
ELMO recruits actin cross-linking family 7 (ACF7) at the cell membrane for microtubule capture and stabilization of cellular protrusions.
Epidermal growth factor induction of front-rear polarity and migration in keratinocytes is mediated by integrin-linked kinase and ELMO2.
CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.
Hernández-Vásquez MN, Adame-García SR, Hamoud N, Chidiac R, Reyes-Cruz G, Gratton JP, Côté JF, Vázquez-Prado J
The Journal of biological chemistry 2017 Jul 21;292(29):12178-12191
The Journal of biological chemistry 2017 Jul 21;292(29):12178-12191
Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion.
Abu-Thuraia A, Gauthier R, Chidiac R, Fukui Y, Screaton RA, Gratton JP, Côté JF
Molecular and cellular biology 2015 Jan;35(1):76-87
Molecular and cellular biology 2015 Jan;35(1):76-87
ELMO recruits actin cross-linking family 7 (ACF7) at the cell membrane for microtubule capture and stabilization of cellular protrusions.
Margaron Y, Fradet N, Côté JF
The Journal of biological chemistry 2013 Jan 11;288(2):1184-99
The Journal of biological chemistry 2013 Jan 11;288(2):1184-99
Epidermal growth factor induction of front-rear polarity and migration in keratinocytes is mediated by integrin-linked kinase and ELMO2.
Ho E, Dagnino L
Molecular biology of the cell 2012 Feb;23(3):492-502
Molecular biology of the cell 2012 Feb;23(3):492-502
CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.
Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS
Cell 2001 Oct 5;107(1):27-41
Cell 2001 Oct 5;107(1):27-41
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC