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Learn21574-1-AP
antibody from Proteintech Group
Targeting: TNFRSF1A
CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60
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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 21574-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21574-1-AP, RRID:AB_10734433
- Product name
- TNFR1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TNFR1 antibody (Cat. #21574-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The Impact of β-1,4-Galactosyltransferase V on Microglial Function.
Identification of a Novel Gene Correlated With Vascular Smooth Muscle Cells Proliferation and Migration in Chronic Thromboembolic Pulmonary Hypertension.
SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.
A unique death pathway keeps RIPK1 D325A mutant mice in check at embryonic day 10.5.
Orientia tsutsugamushi modulates cellular levels of NF-κB inhibitor p105.
The Herbal Medicine Scutellaria-Coptis Alleviates Intestinal Mucosal Barrier Damage in Diabetic Rats by Inhibiting Inflammation and Modulating the Gut Microbiota.
KIAA1522 potentiates TNFα-NFκB signaling to antagonize platinum-based chemotherapy in lung adenocarcinoma.
Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment.
The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway in Breast Cancer Cells.
Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation.
TRADD mediates the tumor necrosis factor-induced apoptosis of L929 cells in the absence of RIP3.
Up-regulation of OLR1 expression by TBC1D3 through activation of TNFα/NF-κB pathway promotes the migration of human breast cancer cells.
Tripartite motif-containing 28 bridges endothelial inflammation and angiogenic activity by retaining expression of TNFR-1 and -2 and VEGFR2 in endothelial cells.
Gene expression comparison reveals distinct basal expression of HOX members and differential TNF-induced response between brain- and spinal cord-derived microvascular endothelial cells.
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Effect of acute lipopolysaccharide-induced inflammation in intracerebroventricular-streptozotocin injected rats.
Huachansu suppresses human bladder cancer cell growth through the Fas/Fasl and TNF- alpha/TNFR1 pathway in vitro and in vivo.
Nox2-dependent signaling between macrophages and sensory neurons contributes to neuropathic pain hypersensitivity.
TNFR1/TNF-α and mitochondria interrelated signaling pathway mediates quinocetone-induced apoptosis in HepG2 cells.
Wang X, Shi N, Hui M, Jin H, Gao S, Zhou Q, Zhang L, Yan M, Shen H
Frontiers in cellular neuroscience 2021;15:723308
Frontiers in cellular neuroscience 2021;15:723308
Identification of a Novel Gene Correlated With Vascular Smooth Muscle Cells Proliferation and Migration in Chronic Thromboembolic Pulmonary Hypertension.
Wang F, Sun C, Lv X, Sun M, Si C, Zhen Y, Guo J, Sun W, Ye Z, Wen J, Liu P
Frontiers in physiology 2021;12:744219
Frontiers in physiology 2021;12:744219
SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.
Shi R, Shi X, Qin D, Tang S, Vermeulen M, Zhang X
Cell & bioscience 2021 Jul 27;11(1):146
Cell & bioscience 2021 Jul 27;11(1):146
A unique death pathway keeps RIPK1 D325A mutant mice in check at embryonic day 10.5.
Zhang Y, Huang K, Zhang Y, Han T, Li L, Ruan C, Sun YH, Shi W, Han W, Wu SQ, Song J, Liu J, Han J
PLoS biology 2021 Aug;19(8):e3001304
PLoS biology 2021 Aug;19(8):e3001304
Orientia tsutsugamushi modulates cellular levels of NF-κB inhibitor p105.
Wangsanut T, Brann KR, Adcox HE, Carlyon JA
PLoS neglected tropical diseases 2021 Apr;15(4):e0009339
PLoS neglected tropical diseases 2021 Apr;15(4):e0009339
The Herbal Medicine Scutellaria-Coptis Alleviates Intestinal Mucosal Barrier Damage in Diabetic Rats by Inhibiting Inflammation and Modulating the Gut Microbiota.
Zhang B, Yue R, Chen Y, Huang X, Yang M, Shui J, Peng Y
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4568629
Evidence-based complementary and alternative medicine : eCAM 2020;2020:4568629
KIAA1522 potentiates TNFα-NFκB signaling to antagonize platinum-based chemotherapy in lung adenocarcinoma.
Wang B, Jing T, Jin W, Chen J, Wu C, Wang M, Liu Y
Journal of experimental & clinical cancer research : CR 2020 Aug 27;39(1):170
Journal of experimental & clinical cancer research : CR 2020 Aug 27;39(1):170
Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment.
Jiang LL, Zhu B, Zhao Y, Li X, Liu T, Pina-Crespo J, Zhou L, Xu W, Rodriguez MJ, Yu H, Cleveland DW, Ravits J, Da Cruz S, Long T, Zhang D, Huang TY, Xu H
The Journal of clinical investigation 2019 May 21;129(8):3103-3120
The Journal of clinical investigation 2019 May 21;129(8):3103-3120
The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway in Breast Cancer Cells.
Egusquiaguirre SP, Yeh JE, Walker SR, Liu S, Frank DA
Neoplasia (New York, N.Y.) 2018 May;20(5):489-498
Neoplasia (New York, N.Y.) 2018 May;20(5):489-498
Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation.
Yang JG, Sun YF, He KF, Ren JG, Liu ZJ, Liu B, Zhang W, Zhao YF
The American journal of pathology 2017 Nov;187(11):2602-2615
The American journal of pathology 2017 Nov;187(11):2602-2615
TRADD mediates the tumor necrosis factor-induced apoptosis of L929 cells in the absence of RIP3.
Chang X, Wang L, Wang Z, Wu S, Zhu X, Hu S, Wang Y, Yu J, Chen G
Scientific reports 2017 Nov 23;7(1):16111
Scientific reports 2017 Nov 23;7(1):16111
Up-regulation of OLR1 expression by TBC1D3 through activation of TNFα/NF-κB pathway promotes the migration of human breast cancer cells.
Wang B, Zhao H, Zhao L, Zhang Y, Wan Q, Shen Y, Bu X, Wan M, Shen C
Cancer letters 2017 Nov 1;408:60-70
Cancer letters 2017 Nov 1;408:60-70
Tripartite motif-containing 28 bridges endothelial inflammation and angiogenic activity by retaining expression of TNFR-1 and -2 and VEGFR2 in endothelial cells.
Wang Y, Li J, Huang Y, Dai X, Liu Y, Liu Z, Wang Y, Wang N, Zhang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 May;31(5):2026-2036
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 May;31(5):2026-2036
Gene expression comparison reveals distinct basal expression of HOX members and differential TNF-induced response between brain- and spinal cord-derived microvascular endothelial cells.
Molino Y, Jabès F, Bonnet A, Gaudin N, Bernard A, Benech P, Khrestchatisky M
Journal of neuroinflammation 2016 Nov 10;13(1):290
Journal of neuroinflammation 2016 Nov 10;13(1):290
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Nie D, Zhang D, Dai J, Zhang M, Zhao X, Xu W, Chen Z, Wang L, Wang Z, Qiao Z
Biology of reproduction 2016 Feb;94(2):31
Biology of reproduction 2016 Feb;94(2):31
Effect of acute lipopolysaccharide-induced inflammation in intracerebroventricular-streptozotocin injected rats.
Murtishaw AS, Heaney CF, Bolton MM, Sabbagh JJ, Langhardt MA, Kinney JW
Neuropharmacology 2016 Feb;101:110-22
Neuropharmacology 2016 Feb;101:110-22
Huachansu suppresses human bladder cancer cell growth through the Fas/Fasl and TNF- alpha/TNFR1 pathway in vitro and in vivo.
Yang T, Shi R, Chang L, Tang K, Chen K, Yu G, Tian Y, Guo Y, He W, Song X, Xu H, Ye Z
Journal of experimental & clinical cancer research : CR 2015 Feb 25;34:21
Journal of experimental & clinical cancer research : CR 2015 Feb 25;34:21
Nox2-dependent signaling between macrophages and sensory neurons contributes to neuropathic pain hypersensitivity.
Kallenborn-Gerhardt W, Hohmann SW, Syhr KM, Schröder K, Sisignano M, Weigert A, Lorenz JE, Lu R, Brüne B, Brandes RP, Geisslinger G, Schmidtko A
Pain 2014 Oct;155(10):2161-70
Pain 2014 Oct;155(10):2161-70
TNFR1/TNF-α and mitochondria interrelated signaling pathway mediates quinocetone-induced apoptosis in HepG2 cells.
Zhang C, Wang C, Tang S, Sun Y, Zhao D, Zhang S, Deng S, Zhou Y, Xiao X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:825-38
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013 Dec;62:825-38
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TNFR1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TNFR1. This antibody recognizes human, mouse antigen. The TNFR1 antibody has been validated for the following applications: ELISA, WB analysis.
