Explore
Validate
LearnAB-225-PB
antibody from Novus Biologicals
Targeting: TNFRSF1A
CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- AB-225-PB - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal TNF RI/TNFRSF1A Antibody
- Antibody type
- Polyclonal
- Description
- Protein A or G purified. Detects human TNF RI/TNFRSF1A in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) TNF RII, rhTNF-alpha , recombinant mouse TNF-alpha , recombinant rat TNF-alpha , and rhTNF-beta is observed. Because this antibody preparation is a total IgG fraction, complete monospecificity cannot be assumed.
- Reactivity
- Human
- Host
- Goat
- Isotype
- IgG
- Vial size
- 1 mg
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references CAR T Cells Targeting MISIIR for the Treatment of Ovarian Cancer and Other Gynecologic Malignancies.
Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer.
A class of small molecules that inhibit TNFalpha-induced survival and death pathways via prevention of interactions between TNFalphaRI, TRADD, and RIP1.
Rodriguez-Garcia A, Sharma P, Poussin M, Boesteanu AC, Minutolo NG, Gitto SB, Omran DK, Robinson MK, Adams GP, Simpkins F, Powell DJ Jr
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):548-560
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):548-560
Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer.
O'Connell J, Porter J, Kroeplien B, Norman T, Rapecki S, Davis R, McMillan D, Arakaki T, Burgin A, Fox Iii D, Ceska T, Lecomte F, Maloney A, Vugler A, Carrington B, Cossins BP, Bourne T, Lawson A
Nature communications 2019 Dec 19;10(1):5795
Nature communications 2019 Dec 19;10(1):5795
A class of small molecules that inhibit TNFalpha-induced survival and death pathways via prevention of interactions between TNFalphaRI, TRADD, and RIP1.
Gururaja TL, Yung S, Ding R, Huang J, Zhou X, McLaughlin J, Daniel-Issakani S, Singh R, Cooper RD, Payan DG, Masuda ES, Kinoshita T
Chemistry & biology 2007 Oct;14(10):1105-18
Chemistry & biology 2007 Oct;14(10):1105-18
No comments: Submit comment
No validations: Submit validation data